Agronin, ME (1998) Personality and psychopathology in late life. Geriatrics 53, Suppl. 1, S35–S40.
American Dietetic Association (1996) Positioning of the ADA: nutrition, aging, and the continuum of care. Journal of the American Dietetic Association 96, 1048–1052.
Araki, A, Sako, Y, lto, H & Orimo, H (1999) Plasma homocysteine, brain MR lesions, and cognitive functions in elderly diabetic patients. Amino Acids 17, 44, Abstr..
Basun, H, Fratiglioni, L & Winblad, B (1994) Cobalamin levels are not reduced in Alzheimer's disease: results from a population based study. Journal of the American Geriatric Society 42, 132–136.
Behl, C (1999) Vitamin E and other antioxidants in neuroprotection. International Journal of Vitamin and Nutrition Research 69, 213–219.
Behl, C & Holsboer, F (1998) Oxidative stress in the pathogenesis of Alzheimer's disease and antioxidant neuroprotection. Fortschrifte der Neurologie Psychiatrie 66, 113–121.
Bell, IR, Edman, JS, Selhub, J, Morrow, FD, Marby, DW, Kayne, HL & Cole, JO (1992) Plasma homocysteine in vascular disease and in nonvascular dementia of depressed elderly people. Acta Psychiatrica Scandinavica 86, 386–390.
Brige, SJ (1997) The role of estrogen in the treatment and prevention of dementia: introduction. American Journal of Medicine 22, 1S–2S.
Birge, SJ (1998) Hormones and the aging brain. Geriatrics 53, S28–S30.
Birkhäuser, MH, Strnad, J, Kämpf, C & Bahro, M (2000) Oestrogens and Alzheimer's disease. International Journal of Geriatric Psychiatry 15, 600–609.
Bonarek, M, Barberger-Gateau, P, Letenneur, L, Deschamps, V, Iron, A, Dubroca, B & Dartigues, JF (2000) Relationships between cholesterol, apolipoprotein E polymorphism and dementia: a cross-sectional analysis from the PAQUID study (2000). Neuroepidemiology 19, 141–148.
Botez, MI, Fontaine, F, Botez, T & Bachevalier, J (1977) Folate-responsive neurological and mental disorders: report of 16 cases. Neuropsychological correlates of computerized transaxial tomography and radionuclide cisternography in folic acid deficiencies. European Neurology 16, 230–246.
Bottiglieri, T (1996) Folic acid, vitamin B12, and neuropsychiatric disorders. Nutrition Reviews 54, 382–390.
Brönstrup, A, Hages, M & Pietrzik, K (1999) Lowering of homocysteine concentrations in elderly men and women. International Journal of Vitamin and Nutrition Research 69, 187–193.
Callahan, CM, Hendrie, HC & Tierney, WM (1995) Documentation and evaluation of cognitive impairment in elderly primary care patients. Annals of International Medicine 122, 422–429.
Carmel, R, Gott, PS, Waters, CH, Cairo, K, Green, R, Bondareff, W, De Giorgio, CM, Cummings, JL, Jacobsen, DW & Buckwalter, G (1995) The frequently low cobalamin levels in dementia usually signify treatable metabolic, neurologic and electrophysiologic abnormalities. European Journal of Haematology 54, 245–253.
Carr, DB, Goate, A, Phil, D & Morris, JC (1997) Current concepts in the pathogenesis of Alzheimer's disease. American Journal of Medicine 103, 3S–10S.
Cattin, L, Bordin, P, Fonda, M, Adams, C, Barbone, I, Bovenzi, M, Manto, A, Pedone, C & Pahor, M (1997) Factors associated with cognitive impairment among older italian inpatients. Journal of American Geriatric Society 45, 1324–1330.
Chandra, RK (1997) Graying of the immune system. Can nutrient supplements improve immunity in the elderly? Journal of the American Medical Association 277, 1398–1399.
Chandra, RK, Imbach, A, Moore, C, Skelton, D & Woolcott, D (1991) Nutrition of the elderly. Canadian Medical Association Journal 145, 1475–1487.
Chapman, J, Wang, N, Treves, TA, Korczyn, AD & Bornstein, NM (1998) ACE, MTHFR, factor V Leiden, and ApoE polymorphisms in patients with vascular and Alzheimer's dementia. Stroke 29, 1401–1404.
Chui, HC, Victoroff, JI, Jagust, W, Saakle, R & Katzman, R (1992) Criteria for the clinical diagnosis of ischemic vascular dementia prepared by the State of California Alzheimer's Disease Diagnostic and Treatment Centers. Neurology 42, 473–480.
Clarke, R, Smith, AD, Jobst, KA, Refsum, H, Sutton, L & Ueland, PM (1998) Folic acid, vitamin B12, and serum homocysteine levels in confirmed Alzheimer's disease. Archives of Neurology 55, 1449–1455.
Desmond, DW, Tatemichi, TK, Paik, M & Stern, Y (1993) Risk factors for cerebrovascular disease as correlates of cognitive function in a stroke-free cohort. Archives of Neurology 50, 162–166.
Diaz Brinton, R & Yamazaki, RS (1998) Advances and challenges in the prevention and treatment of Alzheimer's disease. Pharmaceutical Research 15, 386–398.
Doraiswamy, PM & Steffens, DC (1998) Combination therapy for early Alzheimer's disease: what are we waiting for? Journal of the American Geriatric Society 46, 1322–1324.
Doty, RL (1991) Olfactory capacities in aging and Alzheimer's disease:psychophysical and anatomic considerations. Annals of the New York Academy of Science 640, 20–27.
Durnbaugh, T, Haley, B & Roberts, S (1996) Assessing problem feeding behaviors in mid-stage Alzheimer's disease. Geriatric Nursing 17, 63–67.
Elias, MF (1998) Effects of chronic hypertension on cognitive functioning. Geriatrics 53, S49–S52.
Elsborg, L, Hansen, T & Rafaelsen, OJ (1979) Vitamin B12 concentrations in psychiatric patients. Acta Psychiatrica Scandinavica 59, 145–152.
Fassbender, K, Mielke, O, Bertsch, T, Nafe, B, Fröschen, S & Hennerici, M (1999) Homocysteine in cerebal macroangiography and microangiopathy. Lancet 353, 1586–1587.
Fekkes, D, van der Cammen, TJM, van Loon, CPM, Verschoor, C, van Harskamp, F, de Koning, I, Schudel, WJ & Pepplinkhuizen, L (1998) Abnormal amino acid metabolism in patients with early stage Alzheimer dementia. Journal of Neural Transmission 105, 287–294.
Fernström, JD & Wurtman, RJ (1972) Brain serotonin content: physiological regulation by plasma neutral amino acids. Science 178, 414–416.
Folstein, MF, Folstein, SE & McHugh, PR (1975) Mini Mental State. A practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatric Reasearch 12, 189–198.
Foy, CJ, Passmore, AP, Vahidassr, MD, Young, IS & Lawson, JT (1999) Plasma chain-breaking antioxidants in Alzheimer's disease, vascular dementia and Parkinson's disease. Quarterly Journal of Medicine 92, 39–45.
Fraser, GE, Singh, PN & Bennett, H (1996) Variables associated with cognitive function in elderly California Seventh-day adventist. American Journal of Epidemiology 143, 1181–1190.
Frey, WH 2nd, Najarian, MM, Kumar, KS, Emory, CR, Menning, PM, Frank, JC, Johnson, MN & Ala, TA (1996) Endogenous Alzheimer's brain factor and oxidized glutathione inhibit antagonist binding to the muscarinic receptor. Brain Research 714, 87–94.
Galan, P, Preziosi, P, Monget, AL, Richard, MJ, Arnaud, J & Lesourd, B, Girodon, F, Alfarez, MJ, Bourgeois, C, Keller, H, Iavier, A & Hercberg, S (1997) Effects of trace element and/or vitamin supplementation on vitamin and mineral status, free radical metabolism and immunological markers in elderly long term-hospitalized subjects. International Journal of Vitamin and Nutrition Research 67, 450–460.
Gale, CR, Martyn, CN & Cooper, C (1996) Cognitive impairment and mortality in a cohort of elderly people. British Medical Journal 312, 608–611.
Gomes-Trolin, C, Regland, B & Oreland, L (1995) Decreased methionine adenosyltransferase activity in erythrocytes of patients with dementia disorders. European Neuropsychopharmacology 5, 107–114.
Gomez de Caso, JA, Rodriguez-Artalejo, F, Claveria, LE & Coria, F (1994) Value of Hodkinson's test for detecting dementia and mild cognitive impairment in epidemiological surveys. Neuroepidemiology 13, 64–68.
Goodwin, J, Goodwin, J & Garry, P (1983) Association between nutritional status and cognitive functioning in a healthy elderly population. Journal of the American Medical Association 249, 2917–2921.
Gottfries, CG, Lehmann, W & Regland, B (1998) Early diagnosis of cognitive impairment in the elderly with the focus on Alzheimer's disease. Journal of Neural Transmission 105, 773–786.
Gray, GE (1989) Nutrition and dementia. Journal of the American Dietetic Association 89, 1795–1802.
Haller, J, Weggemans, RM, Ferry, M & Guigoz, Y (1996) Mental health: minimental state examination and geriatric depression score of elderly europeans in the SENECA study of 1993. European Journal of Clinical Nutrition 50, S112–S116.
Huijbregts, PPCW, Feskens, EJM, Räsänen, L, Fidanza, F, Alberti-Fidanza, A, Nissinen, A, Giampaoli, S & Kromhout, D (1998) Dietary patterns and cognitive function in elderly men in Finland, Italy and the Netherlands. European Journal of Clinical Nutrition 52, 826–831.
lhl, R, Brinkmeyer, J, Janner, M & Kerdar, MS (2000) A comparison of ADAS and EEG in the discrimination of patients with dementia of the Alzheimer type from healthy controls. Neuropsychobiology 41, 102–107.
Jama, I, Launer, LJ, Witterman, JCM, den Breeijen, JH, Breteler, MMB & Grobbee, DE (1996) Dietary antioxidants and cognitive function in a population-based sample of elder people. American Journal of Epidemiology 144, 275–280.
Joosten, E, Lesaffre, E, Riezler, R, Ghekiere, V, Dereymaeker, L, Pelemans, W & Dejaeger, E (1997) Is metabolic evidence for vitamin B-12 and folic acid deficiency more frequent in elderly patients with Alzheimer's disease? Journal of Gerontology A Biological Science and Medical Science 52, M76–M79.
Kalmijn, S, Fesikens, EJ, Launer, LJ & Kromhout, D (1997) Polyunsaturated fatty acids, antioxidants, and cognitive functions in very old men. American Journal of Epidemiology 145, 33–41.
Kelly, GS (1998) Folic acids: supplemental forms and therapeutic applications. Alternative Medicine Review 3, 208–220.
Knopman, DS (1998) Current pharmacotherapies for Alzheimer's disease. Geriatrics 53, S31–S34.
Koehler, KM, Pareo-Tubbeh, SL, Romero, LJ, Baumgartner, RN & Garry, PJ (1997) Folic acid nutrition and older adults: challenges and opportunities. Journal of American Dietetic Association 97, 167–173.
Lappalainen, R, Koikkalainen, M, Julkunen, J, Saarinen, T & Mykkänen, H (1998) Association of sociodemographic factors with barriers reported by patients receiving nutrition counselling as part of cardiac rehabilitation. Journal of American Dietetic Association 98, 1026–1029.
Launer, LJ (1992) Overview of incidence studies of dementia conducted in Europe. Neuroepidemiology 11, 2–13.
Lethem, R & Orrell, M (1997) Antioxidants and dementia. Lancet 349, 1189–1190.
Lewis, CJ, Crane, NT, Wilson, DB & Yetley, EA (1999) Estimated folic acid intakes: data updated to reflect food fortification, increased bioavailability, and dietary supplement use. American Journal of Clinical Nutrition 70, 198–207.
Lopez, GH, Ilincheta de Boschero, MG, Castagnet, PI & Giusto, NM (1995) Age-associated changes in the content and fatty acids composition of brain glycerophospholipids. Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology 112, 331–343.
Lutjohann, D, Papassotiropoulos, A, Bjorkhem, K, Locotelli, S, Bagli, M, Oehring, RD, Schlegel, U, Jessen, I, Rao, ML, von Bergmann, K & Heur, R (2000) Plasma 24S-hydroxycholesterol (cerebrosterol) is increased in Alzheimer and vascular demented patients. Journal of Lipid Research 41, 195–198.
McCaddon, A, Davies, G, Hudson, P, Tandy, S & Cattell, H (1998) Total serum homocysteine in senile dementia of Alzheimer type. International Journal of Geriatric Psychiatry 13, 235–239.
Marcus, EL & Berry, EM (1998) Refusal to eat in the elderly. Nutrition Reviews 56, 163–171.
Markesbery, WR & Carney, JM (1999) Oxidative alterations in Alzheimer's disease. Brain Pathology 9, 133–146.
Mattis, S (1976) Mental status examination for organic mental syndrome in the elderly patient. In Geriatric Psychiatry pp. 77–121 [Bellak, L and Karasu, TE, editors]. New York, NY: Grune & Stratton.
Maurer, K, Ihl, R, Dierks, T & Frolich, L (1997) Clinical efficacy of Ginkgo biloba special extract EGb761 in dementia of the Alzheimer type. Journal of Psychiatric Research 31, 645–655.
Miller, JW (1999) Homocysteine and Alzheimer's disease. Nutrition Reviews 57, 126–129.
Moroney, JT, Tang, MX, Berglund, L, Small, S, Merchant, C, Bell, K, Stern, Y & Mageux, R (1999) Low-density lipoprotein cholesterol and the risk of dementia with stroke. Journal of the American Medical Association 21, 254–260.
Morris, MC, Beckett, LA, Scherr, PA, Hebert, LE, Bennett, DA, Field, TS & Evans, DA (1998) Vitamin E and vitamin C supplement use and risk of incident Alzheimer disease. Alzheimer Disease and Associated Disorders 12, 121–126.
Nilsson, K, Gustafson, L, Faldt, R, Andersson, A, Brattstrom, L, Lindgren, A, Israelsson, B & Hultberg, B (1996) Hyperhomocysteinaemia – a common finding in a psychogeriatric population. European Journal of Clinical Investigation 26, 853–859.
Norberg, A & Athlin, E (1989) Eating problems in severely demented patients: issues and ethical dilemmas. Nursing Clinics of North America 24, 781–789.
Paleologos, M, Cumming, RG & Lazarus, R (1998) Cohort study of vitamin C intake and cognitive impairment. American Journal of Epidemiology 148, 45–50.
Parnetti, L, Bottiglieri, T & Lowenthal, D (1997) Role of homocysteine in age-related vascular and non-vascular diseases. Aging (Milano) 9, 241–257.
Pietrzik, K & Brönstrup, A (1997) Folic acid in preventive medicine: a new role in cardiovascular disease, neural tube defects and cancer. Annals of Nutrition and Metabolism 41, 331–343.
Pitchumoni, SS & Doraiswamy, PM (1998) Current status of antioxidant therapy for Alzheimer's disease. Journal of the American Geriatric Society 46, 1566–1572.
Prince, M, Lovestone, S, Cervilla, J, Joels, S, Powell, J, Russ, C & Mann, A (2000) The association between apoE and dementia does not seem to be mediated by vascular factors. Neurology 25, 397–402.
Ramirez-Lassepas, M (1998) Stroke and the aging of the brain and the arteries. Geriatrics 53, S44–S48.
Regland, B, Blennow, K, Germgard, T, Koch-Schmidt, AC & Gottfries, CG (1999) The role of the polymorphic genes apolipoprotein E and methylene-tetrahydrofolic acid reductase in the development of dementia of the Alzheimer type. Dementia and Geriatric Cognitive Disorders 10, 245–251.
Riggs, KM, Spiro, A, Tucker, K & Rush, D (1996) Relations of vitamin B12, vitamin B6, and homocysteine to cognitive performance in the Normative Aging Study. American Journal of Clinical Nutrition 63, 306–314.
Riviere, S, Birlouey-Aragon, I, Nourhashemi, F & Vellas, B (1998) Low plasma vitamin C in Alzheimer patients despite an adequate diet. International Journal of Geriatric Psychiatry 13, 749–754.
Rosenberg, IH & Miller, JW (1992) Nutritional factors in physical and cognitive functions of elderly people. American Journal of Clinical Nutrition 55, 1237S–1243S.
Rosler, M, Retz, W, Thome, J & Riederer, P (1998) Free radicals in Alzheimer's dementia: currently available therapeutic strategies. Journal of Neural Transmission 54, Suppl., 211–219.
Roth, M, Tym, E, Mountjoy, CQ, Huppert, FA, Hendrie, H, Verma, S & Goddard, R (1986) CAMEX: A standardised instrument for the diagnosis of medical disorder in the elderly with special reference to the early detection of dementia. British Journal of Psychiatry 149, 698–709.
Sano, M, Ernesto, C, Thomas, RG, Klauber, MR, Schafer, K, Grundmann, M, Woodbury, P, Growdon, J, Cotman, CW, Pfeiffer, E, Schneider, LS & Thal, LJ (1997) A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. New England Journal of Medicine 336, 1216–1222.
Schmidt, R, Haydn, M, Reinhard, B, Roob, G, Schmidt, H, Schumacher, M, Watzinger, N & Launer, LJ (1998) Plasma antioxidants and cognitive performance in middle-aged and older adults: results of the Austrian Stroke Prevention Study. Journal of American Geriatric Society 46, 1407–1410.
Schneider, LS (1998) New therapeutic approaches to cognitive impairment. Journal of Clinical Psychiatry 59, 8–13.
Selkoe, DJ (1997) Alzheimer's disease: genotypes, phenotype, and treatments. Science 275, 630–631.
Simonson, W (1998) Promising agents for treating Alzheimer's disease. American Journal of Health Systems Pharmacy 55, S11–S16.
Sinclair, AJ, Bayer, AJ, Johnston, J, Warner, C & Maxwell, SR (1998) Altered plasma antioxidant status in subjects with Alzheimer's disease and vascular dementia. International Journal of Geriatric Psychiatry 13, 840–845.
Skoog, I, Lernfelt, B, Landahl, S, Palmertz, B, Andreasson, LA, Nilsson, L, Persson, G, Oden, A & Svanborg, A (1996) Fifteen-year longitudinal study of blood pressure and dementia. Lancet 347, 1141–1145.
Small, GW & Leiter, F (1998) Neuroimaging for diagnosis of dementia. Journal of Clinical Psychiatry 59, 4–7.
Snowdon, DA, Tully, CL, Smith, CD, Perez Riley, K & Markesberry, WR (2000) Serum folate and the severity of atrophy of the neocortex in Alzheimer disease: findings from the Nun Study. American Journal of Clinical Nutrition 71, 993–998.
Solfrizzi, V, Panza, F, Torres, F, Mastroianni, F, Del Parigi, A, Venezia, A & Capurso, A (1999) High monounsaturated fatty acids intake protects against age-related cognitive decline. Neurology 52, 1563–1569.
Swain, R (1995) An update of vitamin B12 metabolism and deficiency states. Journal of Family Practice 41, 595–600.
Tang, JL, Armitage, JM, Lancaster, T, Silagy, CH, Fowler, GH & Neil, HA (1998) Systematic review of dietary intervention trials to lower blood total cholesterol in free-living subjects. British Medical Journal 18, 1213–1220.
Tysoe, C, Galinsky, D, Robinson, D, Brayne, CE, Easton, DF, Huppert, FA, Dening, T, Paybel, ES & Rubinstein, DC (1997) Analysis of alpha-1 antichymotrypsin, persenilin-1, angiotensin-converting enzyme, and methylenetetrahydrofolic acid reductase loci as candidates for dementia. American Journal of Medical Genetics 74, 207–212.
Varela, G (1992) La Dieta Mediterránea (The Mediterranean diet). In Aciete de Oliva de la Comunidad Europea (Olive Oil from the European Community),Madrid: Vegeland-Farma.
Venters, HD Jr, Bonilla, LE, Jensen, T, Garner, HP, Bordayo, EZ, Najarian, MM, Ala, TA, Mason, RP & Frey, WH 2nd (1997) Heme from Alzheimer's brain inhibits muscarinic receptor binding via thiyl radical generation. Brain Research 764, 93–100.
Wehr, H, Parnowski, T, Puzynski, S, Bednarska-Makanick, M, Bisko, M, Kotapka-Minc, S, Rodo, M, Wolkowska, M (2000) Apolipoprotein E genotype and lipid and lipoprotein levels in dementia. Dementia and Geriatric Cognitive Disorders 11, 70–73.
Wolfram, G (1995) Diet therapy in gout. Therapeutische Umshau 52, 524–527.
World Health Organization (1999) World Health Day will focus on ageing. Bulletin of the World Health Organization 77, 293–294.
World Health Organization (2000). The World Health Report 2000. www.who.int/whr