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Nutritional status of drug addicts undergoing detoxification: prevalence of malnutrition and influence of illicit drugs and lifestyle

  • S. K. Nazrul Islam (a1), Kazi Jahangir Hossain (a1), Afsaruddin Ahmed (a1) and Monira Ahsan (a2)
Abstract

The aim of the present study was to investigate the nutritional status of drug addicts, the prevalence of malnutrition among them and the influence of their drug habit and lifestyle factors on their nutritional indices. The study was conducted among 253 male drug addicts, who sought detoxification at the Central Drug Addiction Treatment Hospital, Dhaka, during the period of June 1998–July 1999. One hundred age-, height- and socioeconomic-matched non-addicted healthy men were recruited by convenience as cohort controls. Results showed that the drug addicts had significantly (P<0·001) lowered BMI, haemoglobin, and serum total protein and albumin levels. Clinical signs of nutrient deficiency were diagnosed in about 74 % of drug addicts. The BMI, biochemical values and nutrient deficiency signs indicated that more than 60 % of drug addicts were suffering from multiple malnutrition. One-way ANOVA demonstrated a significant (P<0·05) negative correlation between drug habit, sexually transmitted diseases and selected nutritional indices, and a positive correlation between education, income and the nutritional indices. A series of multiple regression analyses revealed that education, income and age showed significantly predicted BMI and biochemical indices, and the group (non-drug addicts or drug addicts) had a significant negative effect on these parameters in favour of controls.

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Corresponding author
*Corresponding author:Dr S. K. Nazrul Islam, fax +880 2 8615583, email Snislam@bangla.net
References
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Allard JP, Aghdassi E, Chau J, Salit I & Walmsley S (1998) Oxidative stress and plasma antioxidant micronutrients in humans with HIV infection.American Journal of Clinical Nutrition 67, 143147.
Baum MK, Shor-Posner G & Campa A (2000) Zinc status in human immunodeficiency virus infection. Journal of Nutrition 130, 1421S1423S.
Baum MK, Shor-Posner G, Lu Y, Rosner B, Sauberlich HE, Fletcher MA, Szapocznik J, Eisdorfer C, Buring JE & Hennekens CH (1995) Micronutrients and HIV-1 disease progression. AIDS 9, 10511056.
Beatty WW & Borrell GK (2000) Forms of knowledge, cognitive impairment and drug abuse: a demonstration. Progress in Neuro-psychopharmacology and Biological Psychiatry 24, 1722.
Beisel WR (1996) Nutrition in paediatric HIV infection: setting the research agenda Nutrition and immune function: Overview. Journal of Nutrition 126, Suppl., 2611S2615S.
Bluthenthal R, Kral A, Gee L, Erringer E & Edlin E (2000) The effect of syringe exchange use on high risk IDUs: a cohort study. AIDS 14, 605611.
Booth R, Kwiatkowski C & Chitwood D (2000) Sex-related HIV risk behaviors: differential risk among IDUs, crack smokers, and IDUs who smoke crack. Drug and Alcohol Dependence 58, 219226.
Brown SM, Stimmel BT & Taub RN (1974) Immunologic dysfunction in heroin addicts. Archives of Internal Medicine 134, 10011006.
Califano JA Jr (1998) Substance abuse and addiction - the need to know. American Journal of Public Health 88, 911.
Carr DJJ & Serou M (1995) Exogenous and endogenous opioids as biological response modifiers. Immunopharmacology 31, 5971.
Chandra RK (1997) Nutrition and the immune system: an introduction. American Journal of Clinical Nutrition 66, 460S463S.
Chandra RK (2001) Introduction and state of the art and science of nutrition and immunology (abstract). In The 17th International Congress of Nutrition, 2731 August 2001, Vienna, Austria, p. 288 [Elmadfa I and Konig J, editors]. New York and London: Medical and Science Publishers.
Chlebowski RT, Beall G & Grosvenor M (1993) Long term effects of early nutritional support with new enterotropic peptide-based formula vs standard enteral formula in HIV-infected patients: randomized prospective trial. Nutrition 9, 507512.
Choi KH, Xiwen Z, Shuquan Q, Yiee K & Mandel J (2000) HIV risk among patients attending sexually transmitted diseases clinic in China. AIDS and Behavior 4, 111119.
Courssons-Reed ME, Dykstra LA & Lystle DT (1994) Pavlovian conditioning of morphine induced alterations of immune status. Brain Behavior Immunology 8, 204217.
Finnegan LP (1998) Perinatal Morbidity and Mortality in Substance Using Families: Effects and Intervention Strategies, pp. 121. Rockville, MD: NIDA, NIH, US Department of Health and Human Services.
Food and Agriculture Organization (1994) BMI as an indicator of CED. In Body Mass Index: A Measure of Chronic Energy Deficiency in Adults, pp. 1720 [Shetty PS and James WPT, editors]. Rome: FAO.
Food and Agriculture Organization (1995) State of Nutrition in Bangladesh, pp. 166. Dhaka, Bangladesh: FAO.
Ganong WF (1997) Review of Medical Physiology, 18th ed. pp. 481508. New Jersey, USA: Prentice-Hall International, Inc.
Hegde HR, Woodman RC & Sankarn K (1999) Nutrients as modulators of energy in AIDS. Journal of the Association of Physicians of India 47, 318325.
Himmelgreen DA, Perez-Escamilla R, Segura-Millan S, Romero-Daza N, Tansescu M & Sin M (1998) A comparison of the nutritional status and food security of drug-using and non-drug-using Hispanic women in Hartford, Connecticut. American Journal of Physical Anthropology 107, 351361.
International Development Research Centre and World Health Organization (1991) Designing and Conducting Health System Research Projects, vol. 2, part 1, pp. 195218 [Varkevisser CM, Pathmanathan I and Brooconlee A, editors]. Geneva: WHO.
Islam SN, Hossain KJ & Ahsan M (2000) Sexual life style, drug habit and sociodemographic status of the drug addicts in Bangladesh. Public Health 114, 389392.
Islam SN, Hossain KJ & Ahsan M (2001) Original communication: Serum vitamin E, C and A status of the drug addicts undergoing detoxification: influence of drug habit, sexual practice and life style factors. European Journal of Clinical Nutrition 55, 10221027.
Johnson A & Gerstein DR (1998) Initiation of use of alcohol, cocaine, and other substances in US birth cohorts since 1919. American Journal of Public Health 88, 2733.
Kotler DP (1998) Antioxidant therapy and HIV infection. American Journal of Clinical Nutrition 67, 79.
Latham MC (1997) Human Nutrition in the Developing World FAO, Food and Nutrition Series no 29, pp. 147156. Rome: FAO.
Leklem JE (1996) Vitamin B6. In Present Knowledge in Nutrition, 7th ed. pp. 174183 [Ziegler EE and Filer LJ Jr, editors]. Washington, DC: ILSI Press.
Levine M, Rumsey S & Wang Y (1996) Vitamin C. In Present Knowledge in Nutrition, 7th ed. pp. 146159 [Ziegler EE and Filer LJ Jr, editors]. Washington, DC: ILSI Press.
Marangon K, Herbeth B, Lecomte E, Paul-Dauohin A, Grolier P, Chancerelle Y, Artur Y & Siest G (1998) Diet, antioxidant status, and smoking habits in French men. American Journal of Clinical Nutrition 67, 231239.
Mason S & Swash M (1980) The mouth and throat. In Hutchison's Clinical Method, 17th ed. pp. 6270 [Mason S and Swash M, editors]. London: ELBS, A Baillieze Tindall Publications.
Miyagi AU, Chuang T, Lam KM, Kung HF, Wang JM, Osburn BI & Chuang RY (2000) Opioids suppress chemokine-mediated migration of monkey neutrophils and monocytes – an instant response. Immunopharmacology 47, 5362.
Mohs ME, Watson RR & Leonard-Green T (1990) Nutritional effects of marijuana, heroin, cocaine and nicotine. Journal of the American Dietetic Association 90, 12611267.
Morabia A, Fabre J, Chee E, Zeger S, Orsat E & Robert A (1989) Diet and opiate addiction: a quantitative assessment of the diet of non-institutionalized opiate addicts. British Journal of Addicts 84, 173180.
Nagati K (2001) Multiple approaches to micronutrient deficiency in developing countries (abstract). In The 17th International Congress of Nutrition, 2731 August 2001, Vienna, Austria, p. 7 [Elmadfa I and Konig J, editors]. New York and London: Medical and Science Publishers.
Ogilvie C & Evans CC (1987) External manifestation of disease. In Chamberlain's Symptoms and Signs in Clinical Medicine, 11th ed. pp. 3670 [Ogilvie C and Evans CC, editors]. Bristol: ELBS, IOP Publishing Ltd.
Rand ML & Murray RK (2000) Plasma proteins, immunoglobulins, and blood coagulation. In Harpar's Biochemistry, 25th ed. pp. 737762 [Murray RK, Granner DK, Mayes PA and Rodwell VW, editors]. Stamford, CT: Appleton and Lange.
Rouveix B (1992) Opiates and immune function: consequence on infectious disease with special reference to AIDS. Therapie 47, 503512.
Scrimshaw NS & SanGiovanni JP (1997) Synergism of nutrition, infection, and immunity: an overview. American Journal of Clinical Nutrition 66, 464S477S.
Shearman DJC (1996) Disease of the alimentary tract and pancreas. In Davidson's Principle and Practice of Medicine, 17th ed. pp. 405482 [Edwards CRW, Bouchier D, Haslett C and Chilverse E, editors]. Edinburgh: ELBS, Churchill Livingstone.
Smith DK, Gwinn M, Selik RM, Miller KS, Dean-Gaitor HD, Ma'at PI, DeCock KM & Gayle HD (2000) HIV/AIDS among African Americans: progress or progression? AIDS 14, 12371248.
Solis-Pereyra B, Aattouri N & Lemonnier D (1997) Role of food in the stimulation of cytokine production. American Journal of Clinical Nutrition 66, 521S525S.
Thomas PT, Bhargana HN & House RV (1995) Immunomodulatory effects of in vitro exposure to morphine and its metabolites.Pharmacology 50, 5162.
United Nations International Drug Control Programme (1997) Recent trends and development in cultivation, production, trafficking and consumption: an overview. In World Drug Report, pp. 1643. New York: UNDCP, Oxford University Press.
Varela P, Marcos A, Ripoll S, Santacruz I & Requejo AM (1997a) Effects of human immunodeficiency virus infection and detoxification time on anthropometric measurements and dietary intake of male drug addicts. American Journal of Clinical Nutrition 66, 509S514S.
Varela P, Marcos A, Santacruz I, Ripoll S & Requejo AM (1997b) Human immunodeficiency virus infection and nutritional status in female drug addicts undergoing detoxification: anthropometric and immunologic assessments. American Journal of Clinical Nutrition 66, 504S508S.
Vasko ME (1992) Drug abuse and dependence. In Goth's Medical Pharmacology, 13th ed. pp. 336353 [Clerk WO, Brater DE and Johnson AR, editors]. St. Louis, USA: Mosby Year Book.
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British Journal of Nutrition
  • ISSN: 0007-1145
  • EISSN: 1475-2662
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