Skip to main content Accessibility help
×
×
Home

Oatmeal porridge: impact on microflora-associated characteristics in healthy subjects

  • Jørgen Valeur (a1), Nathalie G. Puaschitz (a2), Tore Midtvedt (a3) and Arnold Berstad (a1)
Abstract

Oatmeal porridge has been consumed for centuries and has several health benefits. We aimed to investigate the effect of oatmeal porridge on gut microflora functions. A total of ten healthy subjects ingested 60 g oatmeal porridge daily for 1 week. The following microflora-associated characteristics were assessed before and after the intervention: intestinal gas production following lactulose ingestion, faecal excretion of SCFA and faecal levels of urease and β-galactosidase. In addition, rectal levels of PGE2 were measured. Microbial fermentation as evaluated by intestinal gas production and excretion of SCFA did not change significantly following the dietary intervention. However, faecal levels of β-galactosidase and urease decreased after eating oatmeal porridge (P=0·049 and 0·031, respectively). Host inflammatory state, as measured by rectal levels of PGE2, also decreased, but the change was not significant (P=0·168). The results suggest that oatmeal porridge has an effect on gut microbial functions and may possess potential prebiotic properties that deserve to be investigated further.

  • View HTML
    • Send article to Kindle

      To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle.

      Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      Oatmeal porridge: impact on microflora-associated characteristics in healthy subjects
      Available formats
      ×
      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Dropbox.

      Oatmeal porridge: impact on microflora-associated characteristics in healthy subjects
      Available formats
      ×
      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Google Drive.

      Oatmeal porridge: impact on microflora-associated characteristics in healthy subjects
      Available formats
      ×
Copyright
Corresponding author
* Corresponding author: J. Valeur, email jorgen.valeur@lds.no
References
Hide All
1. Moore-Coyler, RJ (1995) Oats and oat production in history and pre-history. In The Oat Crop: Production and Utilization, pp. 133 [RW Welch, editor]. London: Chapman & Hall.
2. Fitzsimmons, R (2012) Oh, what those oats can do. Quaker oats, the Food and Drug Administration, and the market value of scientific evidence 1984 to 2010. Compr Rev Food Sci Food Saf 11, 5699.
3. Rasane, P, Jha, A, Sabikhi, L, et al. (2015) Nutritional advantages of oats and opportunities for its processing as value added foods – a review. J Food Sci Technol 52, 662675.
4. Cloetens, L, Ulmius, M, Johansson-Persson, A, et al. (2012) Role of dietary beta-glucans in the prevention of the metabolic syndrome. Nutr Rev 70, 444458.
5. Thies, F, Masson, LF, Boffetta, P, et al. (2014) Oats and bowel disease: a systematic literature review. Br J Nutr 112, Suppl. 2, S31S43.
6. Hughes, SA, Shewry, PR, Gibson, GR, et al. (2008) In vitro fermentation of oat and barley derived beta-glucans by human faecal microbiota. FEMS Microbiol Ecol 64, 482493.
7. Drzikova, B, Dongowski, G & Gebhardt, E (2005) Dietary fibre-rich oat-based products affect serum lipids, microbiota, formation of short-chain fatty acids and steroids in rats. Br J Nutr 94, 10121025.
8. Snart, J, Bibiloni, R, Grayson, T, et al. (2006) Supplementation of the diet with high-viscosity beta-glucan results in enrichment for lactobacilli in the rat cecum. Appl Environ Microbiol 72, 19251931.
9. Rose, DJ (2014) Impact of whole grains on the gut microbiota: the next frontier for oats? Br J Nutr 112, Suppl. 2, S44S49.
10. Midtvedt, T, Björneklett, A, Carlsten-Duke, B, et al. (1985) The influence of antibiotics upon microflora associated characteristics in man and animals. In Germfree Research; Microflora Control and Its Application to the Biochemical Sciences. Progress in Clinical and Biological Research, vol. 181, pp. 241244 [BS Wostman, editor]. New York: Alan R. Liss Corporation.
11. Longstreth, GF, Thompson, WG, Chey, WD, et al. (2006) Functional bowel disorders. Gastroenterology 130, 14801491.
12. Levitt, MD, Furne, JK, Kuskowski, M, et al. (2006) Stability of human methanogenic flora over 35 years and a review of insights obtained from breath methane measurements. Clin Gastroenterol Hepatol 4, 123129.
13. Zijlstra, JB, Beukema, J, Wolthers, BG, et al. (1977) Pretreatment methods prior to gaschromatographic analysis of volatile fatty acids from faecal samples. Clin Chim Acta 78, 243250.
14. Høverstad, T, Fausa, O, Bjørneklett, A, et al. (1984) Short-chain fatty acids in the normal human feces. Scand J Gastroenterol 19, 375381.
15. Tjellström, B, Högberg, L, Stenhammar, L, et al. (2012) Effect of exclusive enteral nutrition on gut microflora function in children with Crohn’s disease. Scand J Gastroenterol 47, 14541459.
16. Peters, TJ, Heath, JR, Wansbrough-Jones, MH, et al. (1975) Enzyme activities and properties of lysosomes and brush borders in jejunal biopsies from control subjects and patients with coeliac disease. Clin Sci Mol Med 48, 259267.
17. Andersen, KJ, Schjonsby, H & Skagen, DW (1983) Enzyme activities in human and rat jejunal mucosa. Scand J Gastroenterol 18, 241249.
18. Nysaeter, G, Berstad, K, Weberg, R, et al. (1992) [Diagnosis of Helicobacter pylori infection. Rapid urease test, microscopy of smears and culture from ventricular biopsy compared with the 14C-urea breath test]. Tidsskr Nor Laegeforen 112, 23562358.
19. Egan, LJ, Sandborn, WJ, Mays, DC, et al. (1998) Dialysis of the rectum for sampling drug concentrations in the luminal extracellular fluid of the gut: technique and precision. Aliment Pharmacol Ther 12, 679684.
20. Lauritsen, K, Laursen, LS, Bukhave, K, et al. (1986) Effects of topical 5-aminosalicylic acid and prednisolone on prostaglandin E2 and leukotriene B4 levels determined by equilibrium in vivo dialysis of rectum in relapsing ulcerative colitis. Gastroenterology 91, 837844.
21. David, LA, Maurice, CF, Carmody, RN, et al. (2014) Diet rapidly and reproducibly alters the human gut microbiome. Nature 505, 559563.
22. Kashtan, H, Stern, HS, Jenkins, DJ, et al. (1992) Colonic fermentation and markers of colorectal-cancer risk. Am J Clin Nutr 55, 723728.
23. Hallert, C, Bjorck, I, Nyman, M, et al. (2003) Increasing fecal butyrate in ulcerative colitis patients by diet: controlled pilot study. Inflamm Bowel Dis 9, 116121.
24. Noakes, M, Clifton, PM, Nestel, PJ, et al. (1996) Effect of high-amylose starch and oat bran on metabolic variables and bowel function in subjects with hypertriglyceridemia. Am J Clin Nutr 64, 944951.
25. Hertzler, SR & Savaiano, DA (1996) Colonic adaptation to daily lactose feeding in lactose maldigesters reduces lactose intolerance. Am J Clin Nutr 64, 232236.
26. Szilagyi, A, Rivard, J & Fokeeff, K (2001) Improved parameters of lactose maldigestion using lactulose. Dig Dis Sci 46, 15091519.
27. Brigidi, P, Vitali, B, Swennen, E, et al. (2001) Effects of probiotic administration upon the composition and enzymatic activity of human fecal microbiota in patients with irritable bowel syndrome or functional diarrhea. Res Microbiol 152, 735741.
28. Mobley, HL & Hausinger, RP (1989) Microbial ureases: significance, regulation, and molecular characterization. Microbiol Rev 53, 85108.
29. Shen, TC, Albenberg, L, Bittinger, K, et al. (2015) Engineering the gut microbiota to treat hyperammonemia. J Clin Invest 125, 28412850.
30. Langran, M, Moran, BJ, Murphy, JL, et al. (1992) Adaptation to a diet low in protein: effect of complex carbohydrate upon urea kinetics in normal man. Clin Sci (Lond) 82, 191198.
31. Chu, YF, Wise, ML, Gulvady, AA, et al. (2013) In vitro antioxidant capacity and anti-inflammatory activity of seven common oats. Food Chem 139, 426431.
32. Raa, J (2015) Immune modulation by non-digestible and non-absorbable beta-1,3/1,6-glucan. Microb Ecol Health Dis 26, 27824.
33. Wilczak, J, Blaszczyk, K, Kamola, D, et al. (2015) The effect of low or high molecular weight oat beta-glucans on the inflammatory and oxidative stress status in the colon of rats with LPS-induced enteritis. Food Funct 6, 590603.
Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

British Journal of Nutrition
  • ISSN: 0007-1145
  • EISSN: 1475-2662
  • URL: /core/journals/british-journal-of-nutrition
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Keywords

Metrics

Altmetric attention score

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed