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Guescini, Michele Tiano, Luca Genova, Maria Luisa Polidori, Emanuela Silvestri, Sonia Orlando, Patrik Fimognari, Carmela Calcabrini, Cinzia Stocchi, Vilberto and Sestili, Piero 2017. The Combination of Physical Exercise with Muscle-Directed Antioxidants to Counteract Sarcopenia: A Biomedical Rationale for Pleiotropic Treatment with Creatine and Coenzyme Q10. Oxidative Medicine and Cellular Longevity, Vol. 2017, p. 1.
Ranchordas, Mayur K Rogerson, David Soltani, Hora and Costello, Joseph T 2017. Antioxidants for preventing and reducing muscle soreness after exercise. Cochrane Database of Systematic Reviews,
Shimizu, Kazuhiro Kon, Michihiro Tanimura, Yuko Hanaoka, Yukichi Kimura, Fuminori Akama, Takao and Kono, Ichiro 2015. Coenzyme Q10 supplementation downregulates the increase of monocytes expressing toll-like receptor 4 in response to 6-day intensive training in kendo athletes. Applied Physiology, Nutrition, and Metabolism, Vol. 40, Issue. 6, p. 575.
Sincholle, Daniel 2015. Les compléments antioxydants. Pratiques en nutrition, Vol. 11, Issue. 44, p. 25.
Kim, Ji Yeon Jeong, Sewon Paek, Ju Eun Kim, Joohee Kwak, Jin Sook Lee, Yoon Jung Kang, Tae Seok and Kwon, Oran 2013. Systematic review of the effect of coenzyme Q10 on antioxidant capacity while focused on evaluation of claims for health functional food. Journal of Nutrition and Health, Vol. 46, Issue. 3, p. 218.
Östman, Bengt Sjödin, Anders Michaëlsson, Karl and Byberg, Liisa 2012. Coenzyme Q10 supplementation and exercise-induced oxidative stress in humans. Nutrition, Vol. 28, Issue. 4, p. 403.
Otsuki, Takeshi Shimizu, Kazuhiro Iemitsu, Motoyuki and Kono, Ichiro 2012. Chlorella intake attenuates reduced salivary SIgA secretion in kendotraining camp participants. Nutrition Journal, Vol. 11, Issue. 1,
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Intensive physical exercise may cause muscular injury and increase oxidative stress. The purpose of this study was to examine the effect of an antioxidant, coenzyme Q10 (CoQ10), on muscular injury and oxidative stress during exercise training. Eighteen male students, all elite Japanese kendo athletes, were randomly assigned to either a CoQ10 group (n 10) or a placebo group (n 8) in a double-blind manner. Subjects in the CoQ10 group took 300 mg CoQ10 per d for 20 d, while subjects in the placebo group took the same dosage of a placebo. All subjects practised kendo 5·5 h per d for 6 d during the experimental period. Blood samples were taken 2 weeks before, during (1 d, 3 d, 5 d) and 1 week after the training. Serum creatine kinase (CK) activity and myoglobin (Mb) concentration significantly increased in both groups (at 3 d and 5 d). Serum CK (at 3 d), Mb (at 3 d) and lipid peroxide (at 3 d and 5 d) of the CoQ10 group were lower than those of the placebo group. The leucocyte counts in the placebo group significantly increased (at 3 d) and neutrophils significantly increased in both groups (at 3 d and 5 d). Serum scavenging activity against superoxide anion did not change in either group. These results indicate that CoQ10 supplementation reduced exercise-induced muscular injury in athletes.
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