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    Simopoulos, Artemis 2013. Dietary Omega-3 Fatty Acid Deficiency and High Fructose Intake in the Development of Metabolic Syndrome Brain, Metabolic Abnormalities, and Non-Alcoholic Fatty Liver Disease. Nutrients, Vol. 5, Issue. 8, p. 2901.


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Relationships between dietary macronutrients and adult neurogenesis in the regulation of energy metabolism

  • Marianne A. Yon (a1), Suzanna L. Mauger (a2) and Lucy C. Pickavance (a1)
  • DOI: http://dx.doi.org/10.1017/S000711451200579X
  • Published online: 25 February 2013
Abstract

Of the environmental factors which have an impact on body weight, nutrients are most influential. Within normal limits, hypothalamic and related neuronal populations correct perturbations in energy metabolism, to return the body to its nutritional set-point, either through direct response to nutrients or indirectly via peripheral appetite signals. Excessive intake of certain macronutrients, such as simple carbohydrates and SFA, can lead to obesity and attendant metabolic dysfunction, also reflected in alterations in structural plasticity, and, intriguingly, neurogenesis, in some of these brain regions. Neurogenesis, previously thought to occur only in the embryo, is now known to take place in the adult brain, dependent on numerous stimulating and inhibiting factors, including dietary components. Because of classic associations between neurogenesis and the hippocampus, in learning and cognition, this brain region has also been the focus of attention in the study of links between diet and neurogenesis. Recently, however, a more complete picture of this relationship has been building: not only has the hypothalamus been shown to satisfy the criteria for a neurogenic niche, but appetite-related mediators, including circulating hormones, such as leptin and ghrelin, pro-inflammatory cytokines and the endocannabinoid intracellular messengers, are also being examined for their potential role in mediating neurogenic responses to macronutrients. The present review draws together these observations and investigates whether PUFA may exert their attenuating effects on body weight through the stimulation of adult neurogenesis. Exploration of the effects of nutraceuticals on neurogenic brain regions may encourage the development of new rational therapies in the fight against obesity.

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*Corresponding author: Dr L. C. Pickavance, fax +44 151 706 4080, email lucyp@liverpool.ac.uk
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This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

4AG Dulloo , J Jacquet , G Solinas , et al. (2010) Body composition phenotypes in pathways to obesity and the metabolic syndrome. Int J Obes 34, 417.

5A Fernández-Quintela , I Churruca & MP Portillo (2007) The role of dietary fat in adipose tissue metabolism. Public Health Nutr 10, 11261131.

6KL Stanhope (2012) Role of fructose-containing sugars in the epidemics of obesity and metabolic syndrome. Annu Rev Med 63, 329343.

9BE Levin , L Kang , NM Sanders , et al. (2006) Role of neuronal glucosensing in the regulation of energy homeostasis. Diabetes 55, 122130.

10S Migrenne , C Le Foll , BE Levin , et al. (2010) Brain lipid sensing and nervous control of energy balance. Diabetes Metab 37, 8388.

11HC Chen , JD Roth , BE Schroeder , et al. (2008) Role of islet-, gut-, and adipocyte-derived hormones in the central control of food intake and body weight: implications for an integrated neurohormonal approach to obesity pharmacotherapy. Curr Diabetes Rev 4, 7991.

12KC Berridge , C-Y Ho , JM Richard , et al. (2010) The tempted brain eats: pleasure and desire circuits in obesity and eating disorders. Brain Res 1350, 4364.

13D Pella , K Otsuka & RB Singh (2011) Metabolic syndrome: a disease of the brain. Open Nutraceut J 4, 107118.

14P Södersten , C Bergh , M Zandian , et al. (2011) Obesity and the brain. Med Hypotheses 77, 371373.

18DR LaBelle , JM Cox , AA Dunn-Meynell , et al. (2009) Genetic and dietary effects on dendrites in the rat hypothalamic ventromedial nucleus. Physiol Behav 98, 511516.

21G-Q Chang , V Gaysinskaya , O Karatayev , et al. (2008) Maternal high-fat diet and fetal programming: increased proliferation of hypothalamic peptide-producing neurons that increase risk for overeating and obesity. J Neurosci 28, 1210712119.

24J Li , Y Tang & D Cai (2012) IKKβ/NF-κB disrupts adult hypothalamic neural stem cells to mediate a neurodegenerative mechanism of dietary obesity and pre-diabetes. Nat Cell Biol 14, 9991012.

26DT Balu & I Lucki (2009) Adult hippocampal neurogenesis: regulation, functional implications, and contribution to disease pathology. Neurosci Biobehav Rev 33, 232252.

27PS Eriksson , E Perfilieva , T Bjork-Eriksson , et al. (1998) Neurogenesis in the adult human hippocampus. Nat Med 4, 13131317.

28L Bonfanti & P Peretto (2011) Adult neurogenesis in mammals – a theme with many variations. Eur J Neurosci 34, 930950.

30R Kageyama , I Imayoshi & M Sakamoto (2012) The role of neurogenesis in olfaction-dependent behaviors. Behav Brain Res 227, 459463.

33MP Mattson , W Duan & Z Guo (2003) Meal size and frequency affect neuronal plasticity and vulnerability to disease: cellular and molecular mechanisms. J Neurochem 84, 417431.

34HR Park & J Lee (2011) Neurogenic contributions made by dietary regulation to hippocampal neurogenesis. Ann N Y Acad Sci 1229, 2328.

35D Stangl & S Thuret (2009) Impact of diet on adult hippocampal neurogenesis. Genes Nutr 4, 271282.

36TL Davidson , SE Kanoski , LA Schier , et al. (2007) A potential role for the hippocampus in energy intake and body weight regulation. Curr Opin Pharmacol 7, 613616.

38TF Yuan & O Arias-Carrión (2011) Adult neurogenesis in the hypothalamus: evidence, functions and implications. CNS Neurol Disord Drug Targets 10, 433439.

39Y Xu , N Tamamaki , T Noda , et al. (2005) Neurogenesis in the ependymal layer of the adult rat 3rd ventricle. Exp Neurol 192, 251264.

40MV Kokoeva , H Yin & JS Flier (2007) Evidence for constitutive neural cell proliferation in the adult murine hypothalamus. J Comp Neurol 505, 209220.

42AA Pierce & AW Xu (2010) De novo neurogenesis in adult hypothalamus as a compensatory mechanism to regulate energy balance. J Neurosci 30, 723730.

43VA Rafalski & A Brunet (2011) Energy metabolism in adult neural stem cell fate. Prog Neurobiol 93, 182203.

45AJ Bruce-Keller , JN Keller & CD Morrison (2009) Obesity and vulnerability of the CNS. Biochim Biophys Acta 1792, 395400.

47FS Luppino , LM De Wit , PF Bouvy , et al. (2010) Overweight, obesity, and depression: a systematic review and meta-analysis of longitudinal studies. Arch Gen Psychiatry 67, 220229.

53S Vaynman & F Gomez-Pinilla (2006) Revenge of the “sit”: how lifestyle impacts neuronal and cognitive health through molecular systems that interface energy metabolism with neuronal plasticity. J Neurosci Res 84, 699715.

55VS Malik & FB Hu (2012) Sweeteners and risk of obesity and type 2 diabetes: the role of sugar-sweetened beverages. Curr Diab Rep 12, 195203.

56K Purcell , P Sumithran , C Haywood , et al. (2012) Nutrients that kill: is fructose guilty of causing the obesity epidemic? CAB Rev 7, ID 002.

57JL Sievenpiper , RJ de Souza , A Mirrahimi , et al. (2012) Effect of fructose on body weight in controlled feeding trials: a systematic review and meta-analysis. Ann Intern Med 156, 291304.

58EE Ventura , JN Davis & MI Goran (2011) Sugar content of popular sweetened beverages based on objective laboratory analysis: focus on fructose content. Obesity 19, 868874.

59ME Bocarsly , ES Powell , NM Avena , et al. (2010) High-fructose corn syrup causes characteristics of obesity in rats: increased body weight, body fat and triglyceride levels. Pharmacol Biochem Behav 97, 101106.

62WA Banks (2008) The blood–brain barrier as a cause of obesity. Curr Pharm Des 14, 16061614.

65M Moon , S Kim , L Hwang , et al. (2009) Ghrelin regulates hippocampal neurogenesis in adult mice. Endocr J 56, 525531.

66W Zhang , TR Lin , Y Hu , et al. (2004) Ghrelin stimulates neurogenesis in the dorsal motor nucleus of the vagus. J Physiol 559, 729737.

67W Zhang , Y Hu , TR Lin , et al. (2005) Stimulation of neurogenesis in rat nucleus of the solitary tract by ghrelin. Peptides 26, 22802288.

68J Guo , C Yu , H Li , et al. (2010) Impaired neural stem/progenitor cell proliferation in streptozotocin-induced and spontaneous diabetic mice. Neurosci Res 68, 329336.

70AM Stranahan , TV Arumugam , RG Cutler , et al. (2008) Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons. Nat Neurosci 11, 309317.

71J Cordeira & M Rios (2011) Weighing in the role of BDNF in the central control of eating behavior. Mol Neurobiol 44, 441448.

72EE Noble , CJ Billington , CM Kotz , et al. (2011) The lighter side of BDNF. Am J Physiol Regul Integr Comp Physiol 300, 10531069.

74N Zeeni , C Chaumontet , E Moyse , et al. (2009) A positive change in energy balance modulates TrkB expression in the hypothalamus and nodose ganglia of rats. Brain Res 1289, 4955.

75V Funari , J Crandall & D Tolan (2007) Fructose metabolism in the cerebellum. Cerebellum 6, 130140.

80Y Tozuka , E Wada & K Wada (2009) Diet-induced obesity in female mice leads to peroxidized lipid accumulations and impairment of hippocampal neurogenesis during the early life of their offspring. FASEB J 23, 19201934.

81Y Tozuka , M Kumon , E Wada , et al. (2010) Maternal obesity impairs hippocampal BDNF production and spatial learning performance in young mouse offspring. Neurochem Int 57, 235247.

82A Lindqvist , P Mohapel , B Bouter , et al. (2006) High-fat diet impairs hippocampal neurogenesis in male rats. Eur J Neurol 13, 13851388.

83JP Thaler , CX Yi , EA Schur , et al. (2012) Obesity is associated with hypothalamic injury in rodents and humans. J Clin Invest 122, 153162.

87SA Schreyer , DL Wilson & RC Leboeuf (1998) C57BL/6 mice fed high fat diets as models for diabetes-accelerated atherosclerosis. Atherosclerosis 136, 1724.

90HR Park , M Park , J Choi , et al. (2010) A high-fat diet impairs neurogenesis: involvement of lipid peroxidation and brain-derived neurotrophic factor. Neurosci Lett 482, 235239.

91S Mansouri , H Ortsäter , O Pintor Gallego , et al. (2012) Pituitary adenylate cyclase-activating polypeptide counteracts the impaired adult neural stem cell viability induced by palmitate. J Neurosci Res 90, 759768.

92C Boitard , N Etchamendy , J Sauvant , et al. (2012) Juvenile, but not adult exposure to high-fat diet impairs relational memory and hippocampal neurogenesis in mice. Hippocampus 22, 20952100.

94TF Gamage & AH Lichtman (2012) The endocannabinoid system: role in energy regulation. Pediatr Blood Cancer 58, 144148.

97K Jin , L Xie , SH Kim , et al. (2004) Defective adult neurogenesis in CB1 cannabinoid receptor knockout mice. Mol Pharmacol 66, 204208.

100PW Siri-Tarino , Q Sun , FB Hu , et al. (2010) Saturated fatty acids and risk of coronary heart disease: modulation by replacement nutrients. Curr Atheroscler Rep 12, 384390.

103AM Stranahan , RG Cutler , C Button , et al. (2011) Diet-induced elevations in serum cholesterol are associated with alterations in hippocampal lipid metabolism and increased oxidative stress. J Neurochem 118, 611615.

104IY Kim , IK Hwang , JW Choi , et al. (2009) Effects of high cholesterol diet on newly generated cells in the dentate gyrus of C57BL/6N and C3H/HeN mice. J Vet Med Sci 71, 753758.

105TD Perera , D Lu , L Thirumangalakudi , et al. (2011) Correlations between hippocampal neurogenesis and metabolic indices in adult nonhuman primates. Neural Plast 2011, 16.

106D Cota & G Marsicano (2011) New fat and new neurons: endocannabinoids control neurogenesis in obesity (commentary on Rivera et al.). Eur J Neurosci 33, 15751576.

108ML Monje , H Toda & TD Palmer (2003) Inflammatory blockade restores adult hippocampal neurogenesis. Science 302, 17601765.

109JD Buckley & PRC Howe (2010) Long-chain omega-3 polyunsaturated fatty acids may be beneficial for reducing obesity – a review. Nutrients 2, 12121230.

110DE Cintra , ER Ropelle , JC Moraes , et al. (2012) Unsaturated fatty acids revert diet-induced hypothalamic inflammation in obesity. PLoS One 7, 30571.

111F Gomez-Pinilla & AG Gomez (2011) The influence of dietary factors in central nervous system plasticity and injury recovery. PM R 3, 111116.

112H Poudyal , SK Panchal , V Diwan , et al. (2011) Omega-3 fatty acids and metabolic syndrome: effects and emerging mechanisms of action. Prog Lipid Res 50, 372387.

113HM Su (2010) Mechanisms of n-3 fatty acid-mediated development and maintenance of learning memory performance. J Nutr Biochem 21, 364373.

114A Bordoni , M Di Nunzio , F Danesi , et al. (2006) Polyunsaturated fatty acids: from diet to binding to PPARs and other nuclear receptors. Genes Nutr 1, 95106.

115SC Dyall , GJ Michael & AT Michael-Titus (2010) Omega-3 fatty acids reverse age-related decreases in nuclear receptors and increase neurogenesis in old rats. J Neurosci Res 88, 20912102.

116P Flachs , M Rossmeisl , M Bryhn , et al. (2009) Cellular and molecular effects of n-3 polyunsaturated fatty acids on adipose tissue biology and metabolism. Clin Sci 116, 116.

123VR Venna , D Deplanque , C Allet , et al. (2009) PUFA induce antidepressant-like effects in parallel to structural and molecular changes in the hippocampus. Psychoneuroendocrinology 34, 199211.

125A Wu , Z Ying & F Gomez-Pinilla (2004) Dietary omega-3 fatty acids normalize BDNF levels, reduce oxidative damage, and counteract learning disability after traumatic brain injury in rats. J Neurotrauma 21, 14571467.

127Y Matsuoka (2011) Clearance of fear memory from the hippocampus through neurogenesis by omega-3 fatty acids: a novel preventive strategy for posttraumatic stress disorder? Biopsychosoc Med 5, 18.

128BS Beltz , MF Tlusty , JL Benton , et al. (2007) Omega-3 fatty acids upregulate adult neurogenesis. Neurosci Lett 415, 154158.

130AP Simopoulos (2011) Evolutionary aspects of diet: the omega-6/omega-3 ratio and the brain. Mol Neurobiol 44, 203215.

131T Matsudaira (2007) Attention deficit disorders – drugs or nutrition? Nutr Health 19, 5760.

137MBCV Goncalves , M Agudo , S Connor , et al. (2009) Sequential RARbeta and alpha signalling in vivo can induce adult forebrain neural progenitor cells to differentiate into neurons through Shh and FGF signalling pathways. Dev Biol 326, 305313.

138H Katsuki , E Kurimoto , S Takemori , et al. (2009) Retinoic acid receptor stimulation protects midbrain dopaminergic neurons from inflammatory degeneration via BDNF-mediated signaling. J Neurochem 110, 707718.

139E Kawakita , M Hashimoto & O Shido (2006) Docosahexaenoic acid promotes neurogenesis in vitro and in vivo. Neuroscience 139, 991997.

140M Katakura , M Hashimoto , HM Shahdat , et al. (2009) Docosahexaenoic acid promotes neuronal differentiation by regulating basic helix-loop-helix transcription factors and cell cycle in neural stem cells. Neuroscience 160, 651660.

141AM De Urquiza , S Liu , M Sjoberg , et al. (2000) Docosahexaenoic acid, a ligand for the retinoid X receptor in mouse brain. Science 290, 21402144.

142F Calderon & HY Kim (2007) Role of RXR in neurite outgrowth induced by docosahexaenoic acid. Prostaglandins Leukot Essent Fatty Acids 77, 227232.

143A Cimini & MP Cerù (2008) Emerging roles of peroxisome proliferator-activated receptors (PPARs) in the regulation of neural stem cells proliferation and differentiation. Stem Cell Rev 4, 293303.

146NB Boneva & T Yamashima (2012) New insights into “GPR40–CREB interaction in adult neurogenesis” specific for primates. Hippocampus 22, 896905.

149T Yamashima (2008) A putative link of PUFA, GPR40 and adult-born hippocampal neurons for memory. Prog Neurobiol 84, 105115.

150F Gomez-Pinilla (2011) Collaborative effects of diet and exercise on cognitive enhancement. Nutr Health 20, 165170.

151M Cifuentes , M Pérez-Martín , JM Grondona , et al. (2011) A comparative analysis of intraperitoneal versus intracerebroventricular administration of bromodeoxyuridine for the study of cell proliferation in the adult rat brain. J Neurosci Methods 201, 307314.

156P Luciani , C Deledda , S Benvenuti , et al. (2010) Differentiating effects of the glucagon-like peptide-1 analogue exendin-4 in a human neuronal cell model. Cell Mol Life Sci 67, 37113723.

157E Mossello , E Ballini , M Boncinelli , et al. (2011) Glucagon-like peptide-1, diabetes, and cognitive decline: possible pathophysiological links and therapeutic opportunities. Exp Diabetes Res 2011, ID 281674.

158C Hischer (2012) Potential role of glucagon-like peptide-1 (GLP-1) in neuroprotection. CNS Drugs 26, 871882.

159CT De Souza , EP Araujo , S Bordin , et al. (2005) Consumption of a fat-rich diet activates a proinflammatory response and induces insulin resistance in the hypothalamus. Endocrinology 146, 41924199.

160S Fernández-Veledo , I Nieto-Vazquez , R Vila-Bedmar , et al. (2009) Molecular mechanisms involved in obesity-associated insulin resistance: therapeutical approach. Arch Physiol Biochem 115, 227239.

162C Stryjecki & DM Mutch (2011) Fatty acid–gene interactions, adipokines and obesity. Eur J Clin Nutr 65, 285297.

165PA Carpentier & TD Palmer (2009) Immune influence on adult neural stem cell regulation and function. Neuron 64, 7992.

168N Sinn & PRC Howe (2008) Mental health benefits of omega-3 fatty acids may be mediated by improvements in cerebral vascular function. Biosci Hypotheses 1, 103108.

169E London & TW Castonguay (2010) High fructose diets increase 11β-hydroxysteroid dehydrogenase type 1 in liver and visceral adipose in rats within 24-h exposure. Obesity 19, 925932.

171J Kim , Y Li & BA Watkins (2011) Endocannabinoid signaling and energy metabolism: a target for dietary intervention. Nutrition 27, 624632.

173S Diano , F Naftolin , F Goglia , et al. (1998) Monosynaptic pathway between the arcuate nucleus expressing glial type II iodothyronine 5′-deiodinase mRNA and the median eminence-projective TRH cells of the rat paraventricular nucleus. J Neuroendocrinol 10, 731742.

174N Blondeau , C Nguemeni , DN Debruyne , et al. (2009) Subchronic alpha-linolenic acid treatment enhances brain plasticity and exerts an antidepressant effect: a versatile potential therapy for stroke. Neuropsychopharmacol 34, 25482559.

177S Rössner , M Hammarstrand , E Hemmingsson , et al. (2008) Long-term weight loss and weight-loss maintenance strategies. Obes Rev 9, 624630.

178MM Kaczmarczyk , MJ Miller & GG Freund (2012) The health benefits of dietary fiber: beyond the usual suspects of type 2 diabetes mellitus, cardiovascular disease and color cancer. Metabolism 61, 10581066.

180JM Chell & AH Brand (2010) Nutrition-responsive glia control exit of neural stem cells from quiescence. Cell 143, 11611173.

181R Sousa-Nunes , LL Yee & AP Gould (2011) Fat cells reactivate quiescent neuroblasts via TOR and glial insulin relays in drosophila. Nature 471, 508512.

182AM Stranahan , D Khalil & E Gould (2006) Social isolation delays the positive effects of running on adult neurogenesis. Nat Neurosci 9, 526533.

185TL Davidson , A Monnot , AU Neal , et al. (2012) The effects of a high-energy diet on hippocampal-dependent discrimination performance and blood–brain barrier integrity differ for diet-induced obese and diet-resistant rats. Physiol Behav 107, 2633.

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