1 Renaud, S & de Lorgeril, M (1992) Wine, alcohol, platelets, and the French paradox for coronary heart disease. Lancet 339, 1523–1526.
2 Goldfinger, TM (2003) Beyond the French paradox: the impact of moderate beverage alcohol and wine consumption in the prevention of cardiovascular disease. Cardiol Clin 21, 449–457.
3 Cucciolla, V, Borriello, A, Oliva, A, et al. (2007) Resveratrol: from basic science to the clinic. Cell Cycle 6, 2495–2510.
4 Silan, C (2008) The effects of chronic resveratrol treatment on vascular responsiveness of streptozotocin-induced diabetic rats. Biol Pharm Bull 31, 897–902.
5 Ray, PS, Maulik, G, Cordis, GA, et al. (1999) The red wine antioxidant resveratrol protects isolated rat hearts from ischemia reperfusion injury. Free Radic Biol Med 27, 160–169.
6 Palfi, A, Bartha, E, Copf, L, et al. (2009) Alcohol-free red wine inhibits isoproterenol-induced cardiac remodeling in rats by the regulation of Akt1 and protein kinase C alpha/beta II. J Nutr Biochem 20, 418–425.
7 Wallerath, T, Deckert, G, Ternes, T, et al. (2002) Resveratrol, a polyphenolic phytoalexin present in red wine, enhances expression and activity of endothelial nitric oxide synthase. Circulation 106, 1652–1658.
8 Poussier, B, Cordova, AC, Becquemin, JP, et al. (2005) Resveratrol inhibits vascular smooth muscle cell proliferation and induces apoptosis. J Vasc Surg 42, 1190–1197.
9 Radnai, B, Tucsek, Z, Bognar, Z, et al. (2009) Ferulaldehyde, a water-soluble degradation product of polyphenols, inhibits the lipopolysaccharide-induced inflammatory response in mice. J Nutr 139, 291–297.
10 Delbosc, S, Paizanis, E, Magous, R, et al. (2005) Involvement of oxidative stress and NADPH oxidase activation in the development of cardiovascular complications in a model of insulin resistance, the fructose-fed rat. Atherosclerosis 179, 43–49.
11 Houstis, N, Rosen, ED & Lander, ES (2006) Reactive oxygen species have a causal role in multiple forms of insulin resistance. Nature 440, 944–948.
12 Wei, Y, Whaley-Connell, AT, Chen, K, et al. (2007) NADPH oxidase contributes to vascular inflammation, insulin resistance, and remodeling in the transgenic (mRen2) rat. Hypertension 50, 384–391.
13 Evans, JL, Maddux, BA & Goldfine, ID (2005) The molecular basis for oxidative stress-induced insulin resistance. Antioxid Redox Signal 7, 1040–1052.
14 Baynes, JW (1991) Role of oxidative stress in development of complications in diabetes. Diabetes 40, 405–412.
15 Rüweler, M, Gülden, M, Maser, E, et al. (2009) Cytotoxic, cytoprotective and antioxidant activities of resveratrol and analogues in C6 astroglioma cells in vitro. Chem Biol Interact 182, 128–135.
16 Bhavnani, BR, Cecutti, A, Gerulath, A, et al. (2001) Comparison of the antioxidant effects of equine estrogens, red wine components, vitamin E and probucol on low-density lipoprotein oxidation in postmenopausal women. Menopause 8, 408–419.
17 Sharma, S, Anjaneyulu, M, Kulkarni, SK, et al. (2006) Resveratrol, a polyphenolic phytoalexin, attenuates diabetic nephropathy in rats. Pharmacology 76, 69–75.
18 Kumar, A, Kaundal, RK, Iyer, S, et al. (2007) Effects of resveratrol on nerve functions, oxidative stress and DNA fragmentation in experimental diabetic neuropathy. Life Sci 80, 1236–1244.
19 Cockcroft, DW & Gault, MH (1976) Prediction of creatinine clearance from serum creatinine. Nephron 16, 31–41.
20 Nagaretani, H, Nakamura, T, Funahashi, T, et al. (2001) Visceral fat is a major contributor for multiple risk factor clustering in Japanese men with impaired glucose tolerance. Diabetes Care 24, 2127–2133.
21 Matthews, DR, Hosker, JP, Rudenski, AS, et al. (1985) Homeostasis model assessment: insulin resistance and B-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28, 412–419.
22 Stumvoll, M, Mitrakou, A, Pimenta, W, et al. (2000) Use of the oral glucose tolerance test to assess insulin release and insulin sensitivity. Diabetes Care 23, 295–301.
23 Molnár, GA, Wagner, Z, Markó, L, et al. (2005) Urinary ortho-tyrosine excretion in diabetes mellitus and renal failure: evidence for hydroxyl radical production. Kidney Int 68, 2281–2287.
24 Wagner, L, Laczy, B, Tamaskó, M, et al. (2007) Cigarette smoke-induced alterations in endothelial nitric oxide synthase phosphorylation: role of protein kinase C. Endothelium 4, 245–255.
25 Chan, WH (2005) Effect of resveratrol on high glucose-induced stress in human leukemia K562 cells. J Cell Biochem 94, 1267–1279.
26 Yen, GC, Duh, PD & Lin, CW (2003) Effects of resveratrol and 4-hexylresorcinol on hydrogen peroxide-induced oxidative DNA damage in human lymphocytes. Free Radic Res 37, 509–514.
27 Kanauchi, M, Kimura, K, Akai, Y, et al. (2004) Insulin resistance and pancreatic beta-cell function in patients with hypertensive kidney disease. Nephrol Dial Transplant 19, 2025–2029.
28 Thirunavukkarasu, M, Penumathsa, SV, Koneru, S, et al. (2007) Resveratrol alleviates cardiac dysfunction in streptozotocin-induced diabetes: role of nitric oxide, thioredoxin, and heme oxygenase. Free Radic Biol Med 43, 720–729.
29 Rivera, L, Morón, R, Zarzuelo, A, et al. (2009) Long-term resveratrol administration reduces metabolic disturbances and lowers blood pressure in obese Zucker rats. Biochem Pharmacol 77, 1053–1063.
30 Avogaro, A, de Kreutzenberg, SV & Fadini, GP (2008) Oxidative stress and vascular disease in diabetes: is the dichotomization of insulin signaling still valid? Free Radic Biol Med 44, 1209–1215.
31 Baur, JA & Sinclair, DA (2006) Therapeutic potential of resveratrol: the in vivo evidence. Nat Rev Drug Discov 5, 493–506.
32 Perdew, GH, Hollingshead, BD, Dinatale, BC, et al. (2010) Estrogen receptor expression is required for low-dose resveratrol-mediated repression of aryl hydrocarbon receptor activity. J Pharmacol Exp Ther 335, 273–283.