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Selenium in global food systems

  • Gerald F. Combs (a1)
Abstract

Food systems need to produce enough of the essential trace element Se to provide regular adult intakes of at least 40 μg/d to support the maximal expression of the Se enzymes, and perhaps as much as 300 μg/d to reduce risks of cancer. Deprivation of Se is associated with impairments in antioxidant protection, redox regulation and energy production as consequences of suboptimal expression of one or more of the Se-containing enzymes. These impairments may not cause deficiency signs in the classical sense, but instead contribute to health problems caused by physiological and environmental oxidative stresses and infections. At the same time, supranutritional intakes of Se, i.e. intakes greater than those required for selenocysteine enzyme expression, appear to reduce cancer risk. The lower, nutritional, level is greater than the typical intakes of many people in several parts of the world, and few populations have intakes approaching the latter, supranutritional, level. Accordingly, low Se status is likely to contribute to morbidity and mortality due to infectious as well as chronic diseases, and increasing Se intakes in all parts of the world can be expected to reduce cancer rates.

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*Corresponding author: Dr Gerald F. Combs Jr, fax +1 607 255 1033, email gfc2@cornell.edu
References
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Aaseth, J, Aadland, E & Thomassen, Y (1987) Serum selenium in patients with short bowel syndrome. In Selenium in Biology and Medicine vol. B, pp. 976980 [GF Combs, Jr, JE, Spallholz, OA, Levander & JE, Oldfield, editors]. Westport, CN: AVI Publishing Co.
Abdullev, GM (1976) Selenium levels in healthy subjects and those with certain haematological diseases. Selen v Biologii 1, 136139.
Ahlrot-Westerlund, B, Plantin, LO, Savic, I, Siden, A, Svensson, J (1987) Selenium in plasma, erythrocytes, and platelets from patients with multiple sclerosis. In Selenium in Biology and Medicine vol. B, pp. 981984 [GF Combs, Jr, JE, Spallholz, OA, Levander & JE, Oldfield, editors]. Westport, CN: AVI Publishing Co.
Aihara, K, Nishi, Y, Hatano, S, Kihura, M, Yoshimitsu, K, Takeichi, N, Ito, T, Ezaki, H & Usui, T(1984) Zinc, copper, manganese and selenium metabolism in thyroid disease. American Journal of Clinical Nutrition 40, 2635.
Åkesson, B, Johansson, U (1987) Selenium status in patients with liver cirrhosis. In Selenium in Biology and Medicine vol. B, pp. 968975 [GF Combs, Jr, Spallholz, JE, Levander, OA & Oldfield, JE, editors]. Westport, CN: AVI Publishing Co.
Alegria, A, Barbera, R, Farre, R, Ferrer, E, Legarda, MJ & Torres, MA (1998) Optimization of selenium determination in human milk and whole blood by flow injection hydride atomic absorption spectrometry. Journal of the Association of Analytical Chemists International 81, 457461.
Alfthan, G (1988) Longitudinal study on the selenium status of healthy adults in Finland during 1975–1984. Nutrition Research 8, 467476.
Alfthan, G, Aro, A, Arvilommi, H & Huttunen, JK (1991) Selenium metabolism and platelet glutathione peroxidase activity in health Finnish men: effects of selenium yeast, selenite, and selenate. American Journal of Clinical Nutrition 53, 120125.
Alfthan, G, Bogye, G, Aro, A & Feher, J (1992) The human selenium status in Hungary. Journal of Trace Elements and Electrolytes in Health and Disease 6, 233238.
Allan, CB, Lacourciere, GM & Stadtman, TC (1999) Responsiveness of selenoproteins to dietary selenium. Annual Reviews of Nutrition 19, 116.
Allard, JP, Aghdassi, E, Chau, J, Salit, I & Walmsley, S (1998) Oxidative stress and plasma antioxidant nutrients in humans with HIV infection. American Journal of Clinical Nutrition 57, 143147.
Allaway, WH, Cary, EE, Ehlig, CF (1967) The cycling of low levels of selenium in soils, plants and animals. In Selenium in Biomedicine, pp. 273296 [Muth, OH, Oldfield, JE & Weswig, PH, editors]. Westport, CN: AVI Publishing Co.
Allaway, WH, Kubota, J, Losee, F & Roth, M (1968) Selenium, molybdenum and vanadium in human blood. Archives in Environmental Health 16, 342348.
Allaway, WH, Moore, DP, Oldfield, JE & Muth, OH (1966) Movement of physiological levels of selenium from soils to plants to animals. Journal of Nutrition 88, 411418.
Anttolainen, M, Valsta, LM, Alfthan, G, Keemola, P, Salminen, I & Tamminen, M (1996) Effect of extreme fish consumption on dietary and plasma antioxidant levels and fatty acid composition. European Journal of Clinical Nutrition 50, 741746.
Arnaud, J, Favier, A, Zarski, JP, Rachall, M, Labadie, H, Beaugrand, M (1988) Serum selenium in alcoholic disease Selenium in Medicine and Biology, pp. 273276. [Neève, J, Favier, A, editors]. New York, NY: de Gruyter.
Arnaud, J, Prual, A, Preziosi, P, Cherouvrier, F, Favier, A, Galan, P & Hercberg, S (1993) Effect of iron supplementation during pregnancy on trace element (Cu, Se, Zn) concentrations in serum and breast milk from Nigerian women. Annals of Nutrition and Metabolism 37, 262271.
Aro, A & Alfthan, G (1998) Effects of selenium supplementation of fertilizers on human nutrition and selenium status. In Environmental Chemistry of Selenium, pp. 8197 [FrankenbergerJrand, WT, Engberg, RA, editors]. New York, NY: Marcel Dekker.
Aro, A, Alfthan, G, Varo, P (1989) Se supplementation of fertilizers has increased the Se intake and serum-Se concentration of Finnish people. In Selenium in Biology and Medicine pp. 242245 [Wendel, A, editors]. New York: Springer-Verlag.
Aro, A, Alfthan, G & Varo, P (1995) Effects of supplementation of fertilizers on human selenium status in Finland. Analyst 120, 841843.
Aro, A, Kumpulainen, J, Alfthan, G, Voshenko, A & Ivanov, V (1994) Factors affecting the selenium intake of people in Transbaikalian Russia. Biological Trace Elements Research 40, 277285.
Arthur, JR, Nicol, F & Beckett, GJ (1993) Selenium deficiency, thyroid hormone metabolism, and thyroid hormone deiodinases. American Journal of Clinical Nutrition 57, 236S239S.
Arvilommi, H, Poikonen, L, Jokinen, I, Muukkonen, O, Rasenen, L, Foreman, J & Huttenen, JK (1983) Selenium and immune functions in humans. Infection and Immunology 41, 185189.
Ashour, MN, Salem, SI, El-Gadban, HM, Elwan, NM & Basu, TK (1999) Antioxidant status in children with protein–calorie malnutrition (PEM) living in Cairo, Egypt. European Journal of Clinical Nutrition 52, 669673.
Aursnes, I, Smith, PB, Arnesen, H & Åkesson, B (1988) Correlation between plasma levels of selenium and antithrombin-III. European Journal of Haematology 40, 711.
Azzini, M, Girelli, D, Olivieri, O, Guarini, P, Stanzial, AM, Frigo, A, Milanino, R, Bambara, LM & Carrocher, R (1995) Fatty acids and antioxidant micronutrients in psoriatic arthritis. Journal of Rheumatology 22, 103108.
Backovic, D, Marinkovic, J, Jorga, J, Pavlica, M, Maksimovic, Z & Nikolic, M (1999) Environmental factors, health-related habits, and serum selenium levels in cancer patients and healthy controls. Biological Trace Elements Research 67, 5562.
Barclay, MNI, MacPherson, A & Dixon, J (1995) Selenium content of a range of UK foods. Journal of Food Composition and Analysis 8, 307318.
Barrington, JW, Lindsay, P, James, D, Smith, S & Roberts, A (1996) Selenium deficiency and miscarriage: a possible link?. British Journal of Obstetrics and Gynaecology 103, 130132.
Beck, MA (1997) Rapid genomic evolution of a non-virulent Coxsackievirus B3 in selenium-deficient mice. Biomedical and Environmental Science 10, 307315.
Beck, MA, Kolbeck, PC, Rohr, LH, Morris, VC & Levander, OA (1994) Benign human enterovirus becomes virulent in selenium-deficient mice. Journal of Medical Virology 43, 166170.
Beck, MA, Kolbeck, PC, Shi, Q, Rohr, LH, Morris, VC & Levander, OA (1994) Increased virulence of a human enterovirus (Coxsackievirus B3) in selenium-deficient mice. Journal of Infectious Diseases 170, 351357.
Beck, MA, Shi, Q, Morris, VC & Levander, OA (1995) Rapid genomic evolution of a non-virulent Coxsackievirus B3 in selenium-deficient mice results in selection of identical virulent isolates. Nature Medicine 1, 433436.
Beguin, Y, Bours, V, Delbrouck, JM, Robave, G, Roelands, I, Bury, J, Fillet, G & Weber, G (1989) Relationship of serum selenium levels to tumor activity in acute and non-lymphocytic leukemia. Carcinogenesis 10, 20892091.
Behne, D, Kyriakopoeulos, A, Weiss-Nowak, C, Kalckloesch, M, Westphal, C & Gessner, H (1996) Newly found selenium-containing proteins in the tissues of the rat. Biological Trace Elements Research 55, 99110.
Behne, D & Wolters, W (1979) Selenium content and glutathione peroxidase activity in the plasma and erythrocytes of non-pregnant and pregnant women. Journal of Clinical Chemistry and Clinical Biochemistry 17, 133135.
Bellisola, G, Perona, G, Galassini, S, Moschini, G & Guidi, GC (1993) Plasma selenium and glutathione peroxidase activities in individuals living in the Veneto region of Italy. Journal of Trace Elements and Electrolytes in Health and Disease 7, 242244.
Beker, D, Romíc, Z, KrŠnjavi, H & Zima, Z (1992) A contribution to the world selenium map. Biological Trace Elements Research 33, 4349.
Benemariya, H, Robercht, H & Deestra, H (1993) Daily dietary intake of copper, zinc and selenium by different population groups in Burundi, Africa. Science of the Total Environment 136, 4976.
Bergmann, S, Neumeister, V, Siekmeier, R, Mix, C, Wahrburg, U & Jaross, W (1998) Food supply abundant increase of serum selenium concentrations in middle-aged Dresden women between 1990 and 1996. Toxicology Letters 96-97, 181187.
Berry, MJ, Bannu, L, Harney, JW & Larsen, PR (1993) Functional characterization of the eukaryotic SECIS elements which direct selenocysteine insertion at UGA codons. EMBO Journal 12, 33153322.
Bibow, K, Meltzer, H, Holm, H, Norheim, G & A, Wendel (1989) Blood selenium levels of Norwegians compared to their Se intakes. In Selenium in Biology and Medicine 234237.
Bibow, K, Meltzer, H, Mundal, H, Paulsen, I & Holm, H (1993) Platelet selenium as indicator of wheat selenium intake. Journal of Trace Elements and Electrolytes in Health and Disease 7, 171176.
Bird, SM, Uden, PC, Tyson, JF, Block, E & Denoyer, E (1997) Speciation of selenoamino acids and organoselenium compounds in selenium-enriched yeast using high-performance liquid chromatography-inductively coupled mass spectrometry. Journal of Analytical Atomic Spectrometry 12, 785788.
Bjørneboe, G, Johnson, J, Bjørneboe, A, Bach-Wiig, J, Mørland, J & Drevon, CA (1988) Diminished serum concentration of vitamin E in alcoholics. Annals of Nutrition and Metabolism 32, 5661.
Blot, WJ, Li, JY, Taylor, PR, Guo, W, Dawsey, S, Wang, GQ, Yang, CS, Zheng, SF, Gail, M, Li, GY, Liu, BQ, Tangrea, J, Sun, YH, Liu, F, Fraumeni, F, Zhang, YH & Li, B (1993) Nutrition intervention trials in Linxian, China: supplementation with specific vitamin/mineral combinations, cancer incidence, and disease-specific mortality in the general population. Journal of the National Cancer Institute 85, 14831490.
Bonomini, M, Forster, S, Manfrini, V, De Risio, F, Steiner, MI, Vidovich, MI, Klinkmann, H, Ivanovich, P & Albertazzi, A (1996) Geographic factors and plasma seleniumin uremia and dialysis. Nephron 72, 197204.
Bonomini, M, Manfrini, V, Marini, A, De Risio, F, Niri, L, Klinkmann, H & Albertazzi, A (1995) Hemodialysis with regenerated cellulosic membrane does not reduce plasma selenium levels in chronic uremic patients. Artificial Organs 19, 8185.
Borglund, M & Åkesson, B (1987) Effect of selenium supplementation on the distribution of selenium in plasma proteins of healthy subjects. International Journal of Vitamin and Nutrition Research 58, 97102.
Bortoli, A, Fassin, G, Marchiori, M, Mellow, R, Brugiolo, R & Martelli, F (1990) Selenium status and effects of selenium supplementation in a group of elderly women. Journal of Trace Elements and Electrolytes in Health and Disease 5, 1921.
Bratakos, MS & Ioannou, P (1989) The regional distribution of selenium in Greek cereals. Science of the Total Environment 84, 237247.
Bratakos, MS, Kanaki, H, Vasiliov-Waite, A & Ioannou, P (1990) The nutritional selenium status of healthy Greeks. Science of the Total Environment 96, 161176.
Bratakos, MS, Vouterakos, TP & Ioannou, PV (1990) Selenium status of cancer patients in Greece. Science of the Total Environment 92, 207222.
BrNtter, P, Negretti, V, Rosick, V, Jaffé, W, Menez, H, Tovar, G (1984) Effect of selenium intake in man at high dietary levels of seleniferous areas of Venezuela. In Trace Element Analytical Chemistry in Medicine and Biology, vol. 3, pp. 2946 [Brätter, p & Schramel, P, editors]. New York, NY: de Gruyter.
Bro, S, Berendtsen, H, Norgaard, J, Host, A & Norgensen, P (1988) Serum selenium concentration in maternal and umbilical cord blood. Relation to course and outcome and pregnancy. Journal of Trace Elements and Electrolytes in Health and Disease 2, 165169.
Brtková, A, Magálová, T, Babinská, K & Béderová, A (1994) Serum selenium levels in Slovak population. Biological Trace Elements Research 46, 163171.
Brune, D, Samsahl, K & Wester, PO (1996) A comparison between the amounts of As, Au, Br, Cu, Fe, Mo, Se and Zn in normal and uraemic human whole blood by means of neutron activiation analysis. Clinica Chimica Acta 13, 285291.
Bukkens, S, de Vos, N, Kok, F, Schouten, E, de Bruijin, A & Hofman, A (1990) Selenium status and cardiovascular risk factors in healthy Dutch subjects. Journal of the American College of Nutrition 9, 128135.
Burguera, J, Burguera, M, Gallignani, M, Alarcon, O & Burguera, J (1990) Blood serum selenium in the province of Merida, Venezuela, related to sex, cancer incidence and soil selenium content. Journal of Trace Elements and Electrolytes in Health and Disease 4, 7377.
Burk, RF (1986) Selenium and cancer: meaning of serum selenium levels. Journal of Nutrition 116, 15841586.
Burk, KE, Bedford, RG, Combs, GF, French, I & Skeffington, DR (1992) The effect of topical L-selenomethionine on minimal erythema dose of ultraviolet irradiation in humans. Photodermatology, Photoimmunology Photomedicine 9, 16.
Burk, RF, Pearson, WN, Wood, RP & Viteri, F (1967) Blood selenium levels and in vitro red blood cell uptake of 75Se in kwashiorkor. American Journal of Clinical Nutrition 20, 723733.
Burrini, C, Ghinassi, A, Borghi, G & Fuzzi, G (1993) Determination of normal levels of selenium in blood serum by GFAAS. Giornale Ital in Chimica Clinica 18, 2733.
Butler, J, Thomson, C, Whanger, P & Robinson, M (1991) Selenium distribution in blood fractions of New Zealand women taking organic or inorganic selenium. American Journal of Clinical Nutrition 53, 748754.
Cai, XJ, Uden, PC, Block, E, Zhang, X, Sullivan, JJ & Quimby, BD (1994) Allium chemistry: identification of natural abundance organoselenium compounds volative from garlic, elephant garlic, onions, Chinese chives by headspace gas chromatography with atomic emission detection. Journal of Agricultural and Food Chemistry 42, 20812084.
Cai, XJ, Block, E, Uden, PC, Zhang, X, Sullivan, JJ & Quimby, BD (1995) Allium chemistry: identification of selenoamino acids in ordinary and selenium-enriched garlic, onion and broccoli using gas chromatography with atomic emission detection. Journal of Agricultural and Food Chemistry 43, 17541757.
Calautti, P, Moschine, G, Stievano, BM, Tomio, L, Calzarava, F & Perona, G (1980) Serum selenium levels in malignant lymphoproliferative diseases. Scandinavian Journal of Haematology 23, 6366.
Calomme, M, Hu, J, van den Branden, K & van den Berghe, DA (1995 a) Seleno-Lactobaccillus. An organic selenium source. Biological Trace Elements Research 47, 379383.
Calomme, M, van den Branden, K & Van den Berghe, DA (1995 b) Selenium and Lactobaccillus species. Journal of Applied Bacteriology 79, 331340.
Cao, Y, Liu, H, Xiang, C & Zhou, X (1997) Preparation of instant gruel for selenium supplement. Faming Sheqing Gongkai Shoumingshu.
Casaril, M, Stanzial, AM, Menini, C, Olivieri, O, Girelli, D, Corso, F, Gandini, G, Pinto, F & Corrocher, R (1995) Serum selenium in a healthy population in the Venetian region: relationships with age, sex, weight and alcohol intake. European Journal of Medicine 3, 3539.
Casiot, C, Vacchina, V, Chassaigne, H, Szpunar, J, Potin-Gautier, M & Lobinski, R (1999) An approach to the identification of selenium species in yeast extracts using pneumatically-assisted electrospray tandem mass spectrometry. Analytical Communications 36, 7780.
Ceballos-Picot, I, Merad-Boudia, M, Nicole, A, Thevenin, M, Hellier, G, Legrin, S & Berr, C (1996) Peripheral antioxidant enzyme activities and selenium in elderly subjects and in dementia of Alzheimer's type-place of the extracellular glutathione peroxidase. Free Radicals in Biology and Medicine 20, 579587.
Cenac, A, Simonoff, M, Moretto, P & Djibo, A (1992) A low plasma selenium is a risk factor for peripartum cardiomyopathy: A comparative study in Sahelian Africa. International Journal of Cardiology 36, 5759.
Chaitchik, S, Shenberg, C, Nir-El, Y & Mantel, M (1988) The distribution of selenium in human blood samples of Israeli population-comparison between normal and breast cancer cases. Biological Trace Elements Research 15, 205212.
Chen, CK, Liaw, JM, Juang, JC & Lin, TH (1997) Antioxidant enzymes and trace elements in hemodialyzed patients. Biological Trace Elements Research 58, 149157.
Chen, L (1999) Effect of selenium fertilizer on selenium amount and quality of kiwifruit. Jishou Daxue Xuebao, Ziran Kexueban 20, 5052.
Chou, HT, Yang, HL, Tsou, SS, Ho, RK, Pai, PY & Hsu, HB (1998) Status of trace elements in patients with idiopathic dilated cardiomyopathy in central Taiwan. Chug Hua I Hsueh Tsa Chih 61, 193198.
Chu, YJ, Liu, QY, Hou, C & Yu, SY (1984) Blood selenium concentration in residents of areas in China having a high incidence of lung cancer. Biological Trace Elements Research 6, 133137.
Clark, LC, Combs, GF, Turnbull, BW, Slate, E, Alberts, D, Abele, D, Allison, R, Bradshaw, J, Chalker, D, Chow, J, Curtis, D, Dalen, J, Davis, L, Deal, R & Dellasega, M (1996) The nutritional prevention of cancer with selenium 1983–1993: a randomized clinical trial. Journal of the American Medical Association 276, 19571963.
Clark, LC, Dalkin, B, Krongrad, A, Combs, GF, Turnbull, BW, Slate, EH, Witherington, R, Herlong, JH, Janosko, E, Carpenter, D, Borosso, C, Falk, S & Rounder, J (1998) Decreased incidence of prostate cancer with selenium supplementation: Results of a double-blind cancer prevention trial. British Journal of Urology 81, 730734.
Clark, L, Hixon, L, Combs, G, Patel, N, Reid, M & Sampliner, R (1993) Plasma selenium concentrations predict the rate of colorectal neoplastic polyps. Cancer Epidemiology Biomarkers and Prevention 2, 4146.
Clausen, J, Nielsen, SA & Kristensen, M (1989) Biochemical and clinical effects of an antioxidant supplementation of geriatric patients: A double blind study. Biological Trace Elements Research 20, 135151.
Combs GF, jr (1989) Selenium Nutrition and Cancer Prevention, pp. 389420 [T, Moon & M, Micozzi, editors]. New York, NY: Marcel Dekker.
Combs, GF jr (1994) Essentiality and toxicity of selenium: a critique of the recommended dietary allowance and the reference dose. In Risk Assessment of Essential Elements pp. 167183 [W, Mertz, CO, Abernathy & SS, Olin, editors]. Washington, DC: ILSI Press.
Combs, GF, Clark, LC (1999) Selenium and cancer. In Nutritional Oncology pp. 215222 [Heber, D, Blackburn, GL & Go, VLW, editors]. New York, NY: Academic Press.
Combs, GF & Combs, SB (1986 a) Selenium in the environment. In The Role of Selenium in Nutrition, pp. 1540,New York, NYAcademic Press.
Combs, GF & Combs, SB (1986 b) Selenium in foods and feeds. In The Role of Selenium in Nutrition pp. 41126,New York, NYAcademic Press.
Combs, GF & Combs, SB (1986 c) The biological availability of selenium in foods and feeds. In The Role of Selenium in Nutrition pp. 127177,New York, NYAcademic Press.
Combs, GF & Combs, SB (1986 d) Effects of selenium excesses. In The Role of Selenium in Nutrition pp. 463525,New York, NYAcademic Press.
Combs, GF & Gray, WP (1998) Chemopreventive agents: selenium. Pharmacology and Therapeutics 79, 179192.
Combs, GF & , J (2001) Mechanisms of selenium anticarcinogenesis Physiological Reviews (In the Press).
Coudry, C, Roussel, A, Arnaud, J & Favier, A (1997) EVA Study Group Selenium and antioxidant vitamin and lipoperoxidation levels in preaging French population. Biological Trace Elements Research 57, 183190.
Cser, MA, Sziklai-Laszlo, I, Menzel, H & Lombeck, I (1992) Elevated selenium and erythrocyte glutathione peroxidase activities correlate with HDL-cholesterol and triglycerides in juvenile diabetes. Proceedings of the Fifth International Symposium on Selenium in Biology and Medicine, Vanderbilt University. p. 127 (abstract).
Cser, MA, Sziklai-Laszlo, I, Menzel, H & Lombeck, I (1996) Selenium and glutathione peroxidase activity in Hungarian children. Journal of Trace Elements in Medicine and Biology 10, 167173.
Cumming, F, Fardy, JJ & Woodward, DR (1992) Selenium and human lactation in Australia: Milk and blood selenium levels in lactating women and selenium intakes of their breast-fed infants. Acta Paediatrica Scandinavica 81, 292295.
Damyanova, AA, Akanle, OB & Spyrov, M (1987) Changes in the elemental content of blood components by selenium supplementation in humans. Journal of Radioanalytical and Nuclear Chemistry 113, 431436.
Darling, G, Mathias, P, O'Regan, M & Naughten, E (1992) Serum selenium levels in individuals on PKU diets. Journal of Inherited Metabolic Disease 15, 769773.
Darlow, BA, Inder, TE, Graham, PJ, Sluis, KB, Malpas, TJ, Taylor, BJ & Winterborn, CC (1995) The relationship of selenium status to respiratory outcome in the very low birth weight infant. Pediatrics 96, 314319.
Dastych, M, Koutnik, V & Docekalova, H (1997) Selenium in human and food chain in south Moravian region. Klinische Biochemishe und Metabolism 5, 233236.
Demirci, A & Pometto, AL (1999) Production of organically bound selenium yeast by continuous fermentation. Journal of Agriculture and Food Chemistry 47, 24912495.
Dhindsa, HS, Bergmingham, MA, Mierzwa, J & Sullivan, D (1998) Plasma selenium concentrations in a Sikh population in Sydney, Australia. Analyst 123, 885887.
Dickson, R & Tomlinson, R (1967) Selenium in blood and human tissues. Clinica Chimica Acta 16, 311321.
Djujic, I, Djujic, B & Trajkovic, L (1995) Dietary intake of selenium in Serbia: results for 1991. Naucni Skupovi (Srpska Akademija Nauka i Umetnosti). Odeljenje Prirodno-Matematickih Nauka 6, 8187.
Drobner, C, Röhrig, B, Anke, M, Thomas, G (1997) Selenium intake of adults in Germany depending on sex, time, living area and type of diet. In Trace Elements in Man and Animals-9, pp. 158159 [Fischer, PWF, L'Abbé, MR, Cockell, KA, Gibson, RS, editors]. Ottawa: NRC Research Press.
Duan, Y & Fu, T (1997) Absorption of Se by garlic and effects of Se on growth of garlic. Guangdong Weiliang Yuansu Kexue 4, 5255.
Dubois, F, Nicholas, B, Hoffman, R, Belleville, F, Paysant, P, Kessler, M, Jonon, B, Cao-Huu, T (1988) Blood selenium glutathione peroxidase and cadmium in chronic renal failure patients. In Selenium in Medicine and Biology pp. 289292 [Nève, J & Favier, A, editors]. New York, NY: de Gruyter.
Ducros, V, Faure, P, Ferry, M, Couzy, F, Biajoux, I & Favier, A (1997) The sizes of the exchangeable pools of selenium in elderly women and their relation to institutionalization. British Journal of Nutrition 78, 379396.
Duffield, AJ & Thomson, CD (1999) A comparison of methods of assessment of dietary selenium intakes in Otago, New Zealand. British Journal of Nutrition 82, 131138.
Dutta, SK, Miller, PA, Greenberg, LB & Levander, OA (1983) Selenium and acute alcoholism. American Journal of Clinical Nutrition 38, 713718.
Dworkin, B, Newman, LJ, Berezin, S, Rosenthal, WS, Schwarz, SM & Weiss, L (1987) Low blood selenium levels in patients with cystic fibrosis compared to controls and healthy adults. Journal of Parenteral and Enteral Nutrition 11, 3841.
Dworkin, BM & Rosenthal, WS (1984) Selenium and the alcoholic. Lancet 31, 10151022.
El-Amri, FA, El-Saltani, HA, Dogadkin, NN & Ashour, IA (1994) Determination of trace elements in normal and diabetic whole blood by neutron activation analysis. Biological Trace Elements Research 43–45, 383388.
El-Bayoumy, K (1991) The role of selenium in cancer prevention. In Practice of Oncology, 4th ed., pp. 115 [DeVita, VT, Hellman, S & Rosenberg, SS, editors]. Philadelphia, PA: Lippincott.
Ellis, N, Lloyd, B, Lloyd, RS & Clayton, BE (1984) Selenium and vitamin E, in relation to risk factors for coronary heart disease. Journal of Clinical Pathology 37, 200206.
Ermakov, VV (1992) Biogeochemical regioning problems and the biochemical selenium provinces of the former USSR. Biological Trace Element Research 33, 171185.
Feldman, DS, Smith, DK (1987) Comparison of selenium status in healthy patients from a low-selenium area with that of multiple sclerosis. In Selenium in Biology and Medicine, vol. B, 985991 [Combs Jr, GF, Spallholz, JE, Levander, OA, Oldfield, JE, editors]. Westport, CN: AVI Publishing Co.
Fernandez-Banares, F, Dolz, C, Mingorance, MN, Cabre, E, Lachica, M, Abda-Lacruz, A, Gil, A, Estreve, M, Gine, J & Gassul, M (1990) Low serum selenium concentration in a healthy population resident in Catalunya: a preliminary report. European Journal of Clinical Nutrition 44, 225229.
Ferrer, E, Alegria, A, Barbera, R, Farre, R, Lagarda, MJ & Monleon, J (1999) Whole blood selenium content in pregnant women. Science of the Total Environment 227, 139143.
Finley, JW (1999) The retention and distribution by healthy young men of stable isotopes of selenium consumed as selenite, selenate or hydroponically-grown broccoli are dependent on the isotopic form. Journal of Nutrition 129, 865871.
Fleming, GA (1962) Selenium in Irish soils and plants. Soil Science 94, 2835.
Fleming, GA & Walsh, T (1957) Selenium occurrence in certain Irish soils and its toxic effect on animals. Royal Irish Academy Proceedings 58, 151156.
Fleming, C, Lie, J, McCall, J, O'Brien, J, Baille, E & Thistle, JL (1982) Selenium deficiency and fatal cardiomyopathy in a patient on home parenteral nutrition. Gastroenterology 83, 689693.
Foote, JW, Hinks, LJ & Lloyd, B (1987) Reduced plasma and white blood cell selenium levels in haemodialysis patients. Clinica Chimica Acta 164, 323328.
Forrer, R, Gautschi, K & Lutz, H (1991) Comparative determination of selenium in serum of various animal species and humans by means of electrothermal atomic absorption spectrometry. Journal of Trace Elements and Electrolytes in Health and Disease 5, 101113.
Gambhir, JK & Lali, P (1996) Blood selenium levels in Indians: Delhi area. Journal of Clinical Biochemistry 11, 148151.
Ganther, HE (1999) Selenium metabolism, selenoproteins and mechanisms of cancer prevention: complexities with thioredoxin reductase. Carcinogenesis 20, 16571666.
Gasmi, A, Garnier, R, Galliot-Guilley, M, Gaudillat, C, Quartenoud, B, Buisine, A & Djebbar, D (1997) Acute selenium poisoning. Veterinary and Human Toxicology 39, 304308.
Gebre-Medhin, M, Gustavson, KH, Gamstorp, I & Plantin, LO (1985) Selenium supplementation in X-linked muscular dystrophy. Acta Paediatrica Scandinavica 74, 886890.
Gerber, M, Richardson, S, Chappuis, P (1998) Selenium and other antioxidants in breast cancer. In Selenium in Medicine and Biology, pp. 263266 [J, Nève & A, Favier, editors]. New York, NY: de Gruyter.
Gibson, RS, Martinez, O & MacDonald, A (1985) The zinc, copper and selenium status of a selected sample of Canadian elderly women. Gerontology 40, 2630.
Gissel-Nielsen, G (1975) Selenium concentration in Danish forage crops. Acta Agricultura Scandinavica 25, 216220.
Gissel-Nielsen, G (1998) Effects of selenium supplementation of field crops. In Environmental Chemistry of Selenium, pp. 99112 [WT, Frankenberger #Jr & RA, Engberg, editors]. New York, NY: Marcel Dekker.
Gladyshev, VN, Jeang, KT, Wooton, JC & Hatfield, DL (1998) A new human selenium-containing protein. Purification, characterization and cDNA sequence. Journal of Biological Chemistry 273, 89108915.
Glattre, E, Thomassen, Y, Thoresen, S, Haldorsen, T, Lund-Larsen, P, Theodorsen, L & Aaseth, J (1989) Prediagnostic selenium in a case-control study of thyroid cancer. International Journal of Epidemiology 18, 4549.
Golubkina, NA (1994) Selenium intake of Briansk region population living in radionuclide-contaminated areas. Voprosy Pitania 4, 36.
Golubkina, NA (1997) Selenium content in wheat and rye flour of Russia, CSC and Baltic. Voprosy Pitania 7, 1720.
Golubkina, NA & Alfthan, GV (1999) The human selenium status in 27 regions of Russia. Journal of Trace Elements in Medicine and Biology 13, 1520.
Golubkina, NA, Baturin, AK, Shagova, MV & Martinchik, AN (1998) Human selenium status in Altay region. Voprosy Pitania 8, 1618.
Golubkina, NA, Mal'tsev, G, Bogdanov, NG, Vlaskina, S, Alekseeva, IA & Khotimchenko, SA (1995) Selenium status of the inhabitants in the Kaluga region. Voprosy Pitania 5, 1315.
Golubkina, NA, Parfenova, EO & Rehsetnik, LA (1998 b) The human selenium status in Irkutsk region. Voprosy Pitania 8, 2426.
Golubkina, NA, Shagova, MV & Spirichev, VB (1996) Selenium status of different population groups of the Bashkortostan Republic. Voprosy Pitania 6, 35.
Golubkina, NA, Shagova, MV, Spirichev, VB, Khristenko, PP, Alfthan, D, Laaksonsen, P, Muratov, IM & Vachaeva, NN (1992) The selenium content of food products and the blood of inhabitants of Norilsk. Voprosy Pitania 2, 4345.
Golubkina, NA & Sokolov, IA (1997) Level of selenium supply for inhabitants of the Northern economic area of Russia. Gigiena I Sanitariia 3, 2224.
Golubkina, NA, Sokolov, YA, Hotimchenko, SA, Tutelyan, VA, Zolotov, PA, Olezhko-Ozhevsky, YP, Zhminchenko, VM, Amanova, IY & Mepenzina, OL (1996) Selenium-enriched yeast Saccharomyces cerevisiae. Bioteckhnologiya 5, 5256.
Gondi, F, Pantó, G, Fehér, J, Bogye, G & Alfthan, G (1992) Selenium in Hungary: The rock-soil-human system. Biological Trace Elements Research 35, 299306.
Goodwin, WJ, Lane, HW, Bradford, K, Marshall, MV, Griffen, AC, Geopfert, H & Jesse, RH (1983) Selenium and glutathione peroxidase in patients with epidermoid carcinoma of the oral cavity and oropharynx. Cancer 51, 110115.
Grandjean, P, Nielsen, G, Jorgensen, P & Hormer, H (1992) Reference intervals for trace elements in blood: significance of risk factors. Scandinavian Journal of Clinical and Laboratory Investigation 52, 321337.
Griffiths, NM & Thomson, CD (1974) Selenium in whole blood of New Zealand residents. New Zealand Medical Journal 80, 199202.
Güneral, F & Sunguroğlu, (1995) Fluorometric determination of selenium in plasma, erythrocytes and urine. Tropical Journal of Medical Science 23, 151154.
Guo, P, Xu, JH, Chang, SY, Xu, SJ & Wang, K (1997) Hydrogen peroxide production in chondrocytes induced by fulvic acid and inhibited by selenium. Shengwu Huaxue Zazhi 13, 103107.
Guvenoc, H, Karataos, F & Guvenoc, M (1995) Low levels of selenium in mothers and their newborns in pregnancies with a neural tube defect. Pediatrics 95, 879882.
Hai, VD, Thuy, DH, Bao, DT & Vuong, DH (1984) First investigation on blood selenium of Vietnamese. Reviews in Pharmacology 24, 811.
Hansen, JC, Kromann, N, Wulf, HC & Albøge, K (1984) Selenium and interrelationship with mercury in whole blood and hair in an east Greenlandic population. Science of the Total Environment 38, 3340.
Hardell, L, Danell, M, Nngqvist, CA, Marklund, SL, Fredriksson, M, Zakari, A & Kjellgren, A (1993) Levels of selenium in plasma and glutathione peroxidase in erythrocytes and the risk of breast cancer: A case-control study. Biological Trace Elements Research 36, 99108.
Hardell, L, Degerman, A, Tomic, R, Marklund, SL & Bergors, M (1995) Levels of selenium in plasma and glutathione peroxidase in erythrocytes in patients with prostate cancer or benign hyperplasia. European Journal of Cancer Prevention 4, 9195.
Harrison, I, Littlejohn, D & Fell, GS (1996) Distribution of selenium in human blood plasma and serum. Analyst 121, 189194.
Hatano, S, Aihara, K, Nishi, Y & Usui, T (1985) Trace elements (copper, zinc, manganese, and selenium) in plasma and erythrocytes in relation to dietary intake during pregnancy. Journal of Pediatric Gastroenterology and Nutrition 4, 8792.
He, S (1996) Health margarine containing gamma-linoleic acid and selenium. Faming Sheqing Gongkai Shoumingshu.
Hegoczki, J, Suhajda, A, Janzso, B & Vereczky, G (1997) Yeast enriched with trace elements as a new type of trace element source. Elelmezesi Ipar 51, 338341.
Hill, KE, Lloyd, RS, Yang, JG, Read, R & Burk, RF (1991) The cDNA for rat selenoprotein P, contains 10 TGA codons in the open reading frame. Journal of Biological Chemistry 266, 1005010053.
Hill, KE, Xia, Y, Åkesson, B, Boeglin, ME & Burk, RF (1996) Selenoprotein P, concentration in plasma is an index of selenium status in selenium-deficient and selenium-supplemented Chinese subjects. Journal of Nutrition 126, 138145.
Hinks, LJ, Inwards, KD, Lloyd, B & Clayton, B (1988) Reduced concentrations of selenium in mild Crohn's disease. Journal of Clinical Pathology 41, 198201.
Hu, X & Ding, R (1998) Production of selenium-rich tea in selenium-low plantation. Turang (Nanjing) 30, 3135.
Huang, Y, Yan, G, Wang, G, Chen, Y & Luo, Q (1997) Selenium contents in Se-rich mushroom. Yunnan Daxue Xuebao, Ziran Kexueban 19, 341343.
Hughes, K & Ong, CN (1998) Vitamins, selenium, iron and coronary heart disease risk in Indians, Malays and Chinese in Singapore. Journal of Epidemiology Community Health 57, 181185.
Hussein, L & Bruggeman, J (1999) Selenium analysis of selected Egyptian foods and estimated daily intakes among a population group. Food Chemistry 65, 527532.
Imai, H, Kashiwazaki, H, Suzuki, T, Kabuto, M, Himeno, S, Watanabe, C, Moji, K, Kim, SW, Rivera, JO & Takemoto, TI (1995) Selenium levels and glutathione peroxidase activities in blood in an Andean high-altitude population. Journal of Nutritional Science and Vitaminology 41, 349361.
Imai, H, Suzuki, T, Kashiwazaki, H, Takemoto, T, Izumi, T & Moji, K (1990) Dietary habit and selenium concentrations in erythrocyte and serum in a group of middle-aged and elderly Japanese. Nutrition Research 10, 12051214.
Ip, C (1998) Lessons from basic research in selenium and cancer prevention. Journal of Nutrition 128, 18451854.
Ip, C, Birringer, M, Block, E, Kotrebai, M, Tyson, JF, Uden, PC & Lisk, DJ (2000 a) Chemical speciation influences comparative activity of selenium-enriched garlic and yeast in mammary cancer prevention. Journal of Agricultural and Food Chemistry 48, 20622070.
Ip, C & Ganther, H (1990 b) Activity of methylated forms of selenium in cancer prevention. Cancer Research 50, 12061211.
Ip, C, Ganther, H (1993) Novel strategies in selenium cancer chemoprevention research. In Selenium in Biology and Human Health pp. 170180 [Burk, RF, editor]. New York, NY: Springer-Verlag.
Ip, C & Lisk, D (1994) Characterization of tissue selenium profiles and anticarcinogenic responses in rats fed natural sources of selenium-rich products. Carcinogenesis 15, 573576.
Ip, C, Lisk, DJ & Stoewsand, GS (1992) Mammary cancer prevention by regular garlic and selenium-enriched garlic. Nutrition and Cancer 17, 279286.
Ip, C, Thompson, HJ, Zhu, Z & Ganther, HE (2000) In vitro and in vivo studies of methylselenic acid: evidence that a monomethylated selenium metabolite is critical for cancer chemoprevention. Cancer Research 60, 28822886.
Iwanier, K & Zachara, BA (1995) Selenium supplementation enhances the element concentration in blood and seminal fluid but does not change the spermatozoal quality characteristics in subfertile men. Journal of Andrology 16, 441447.
Iyengar, GV (1984) Reference values for elemental concentrations in some human samples of clinical interest: A preliminary evaluation. Science of the Total Environment 38, 125131.
Jacobson, S & Plantin, LO (1985) Concentration of selenium in plasma and erythrocytes during total parenteral nutrition in Crohn's disease. Gut 26, 5054.
Janghorbani, M, Xia, YM, Whanger, PD, Butler, JA, Olesik, JW & Grunwald, E (1999) Effect of dietary selenium restriction on selected parameters of selenium status in men with high life-long intake. Journal of Nutrition Biochemistry 10, 564572.
Jiang, Y & Xu, G (1989) The relativity between some epidemiological characteristics of Kaschin-Beck disease and selenium deficiency. In Selenium in Biology and Medicine 263269. [Wendel, A, editors]. New York, NY: Springer-Verlag.
Jochum, F, Terwolbeck, K, Meinhold, H, Behne, D, Menzel, H & Lombeck, I (1999) Is there any health risk of low dietary selenium supply in PKU-children?. Nutrition Research 19, 349360.
Joint FoodSafety and Standards Group (1999) Food Surveillance Information Sheet: Dietary Intake of Selenium, no. 126, LondonMinistry of Agriculture, Fisheries and Food.
Judson, GJ & Reuter, DJ (1998) Soil Analysis: An Interpretation Manual. 325329UrrbraeSouth Australia Research and Development Institute.
Kadrabová, J, Madaric, A & Ginter, E (1998) Determination of the daily selenium intake in Slovakia. Biological Trace Elements Research 61, 277286.
Kadrabová, J, Madárič, A, Kováčiková, Z & Ginter, E (1995) Selenium status, plasma zinc, copper and magnesium in vegetarians. Biological Trace Elements Research 50, 1324.
Kadrabová, J, Madárič, A, Kováčiková, Z, Podivínsky, F & Ginter, E (1996 a) Gazdík Selenium status is decreased in patients with intrinsic asthma. Biological Trace Elements Research 50, 241248.
Kadrabová, J, Madárič, A, Šustrová, M & Ginter, E (1996 b) Changed serum trace element profile in Down's syndrome. Biological Trace Elements Research 54, 201206.
Kant, AK, Moser-Veillon, PB & Reynolds, RD (1989) Dietary intakes and plasma concentrations of zinc, copper, iron, magnesium and selenium of young, middle-ages and older men. Nutrition Research 9, 717724.
Kantola, M, Mand, E, Viitak, A, Juravskaja, J, Purkunen, R, Vartianen, T, Saarikoski, S & Pasanen, M (1997) Selenium contents of serum and human milk from Finland and neighboring countries. Journal of Trace Elements in Experimental Medicine 10, 225232.
Karlsson, J, Lundgren, G & Rρnneberg, R (1996) Plasma selenium in healthy man before and after nutratherapy International Journal of Vitamin and Nutrition Research 67, 2733.
Kasperek, K, Lombeck, I, Keim, J, Iyengar, GV, Wang, YX, Feinendegen, LE & Bremer, HJ (1982) Platelet selenium in children with normal and low selenium intake. Biological Trace Elements Research 4, 2934.
Kauppila, A, MNkilN, U, Korpela, H, Viinikka, L, YrjNnheikki, E (1987) Relationship of serum selenium and lipid peroxidation in preeclampsia. In Selenium in Biology and Medicine vol. B, 9961001 [GF Combs, Jr, Spallholz, JE, Levander, OA & Oldfield, JE, editors]. Westport, CN: AVI Publishing Co.
Kauppila, A, Sundström, H, Korpela, H, Viinikka, L, YrjNnheikki, E & HT, haler-Dao (1984) Serum selenium and gynecological cancer: Effect of selenium supplementation on plasma malondialdehyde and serum glutathione peroxidase. In Icosanoids and Cancer, pp. 263266 [Thaler-Dao, H, editor]. New York, NY: Raven Press.
Kavas-Ogly, AA, Lutfullaev, FE, Rafiev, AN, Onishenko, VA, Abbasova, BA, Rish, MA (1995) Selenium intakes by inhabitants of the Samarkland oasis. In Mengen-Spurenelem., Arbeitstag 18th pp. 395399 [Anke, M, editor]. Leipsig: Verlag Harald Schubert.
Keshan Disease Research Group (1979) Observations on effect of sodium selenite in prevention of Keshan Disease. Acta Academia Medica Sinica 1, 7583.
KivelN, SL, MNenpNN, P, Nissinen, A, Alfthan, G, Punsar, S, Enlund, H & Puska, P (1989) Vitamin A, vitamin, E, and selenium status in an aged Finnish male population. International Journal of Vitamin and Nutrition Research 59, 373380.
Klapec, T, Mandic, ML, Grigic, J, Primorac, L, Ikic, M, Lovric, T, Grigic, Z & Herceg, Z (1998) Daily dietary intake of selenium in eastern Croatia. Science of the Total Environment 217, 127136.
Knekt, P, Aromaa, A, Maatela, J, Alfthan, G, Aaran, RK, Hakama, M, Hakulinen, T, Peto, R & Teppo, L (1990) Serum selenium and subsequent risk of cancer among Finnish men and women. Journal of the National Cancer Institute 82, 864868.
Kocyigit, A, Erel, O, Gurel, MS, Avci, S & Aktepe, N (1998) Alterations of serum selenium, zinc, copper and iron concentrations and some related antioxidant activities in patients with cutaneous Leishmaniasis. Biological Trace Elements Research 65, 271281.
Koehler, H, Peters, H, Pankau, H & Duck, HJ (1988) Selenium in cardiology and angiology. Biological Trace Elements Research 15, 157166.
Kok, FJ, Hofman, A (1989) Selenium status and cardiovascular disease: Dutch epidemiologic data. In Selenium in Biology and Medicine, pp. 214218 [Wendel, A, editors]. New York, NY: Springer-Verlag.
Kopsell, DA & Randall, WM (1999) Selenium accumulation in a rapid-cycling Brassica oleracea population responds to increasing sodium selenate concentrations. Journal of Plant Nutrition 22, 927937.
Korpela, H, Loueniva, R, Yrajanheikki, E & Kauppila, A (1984) Selenium concentration in maternal and umbilical cord blood, placenta and amniotic membranes. International Journal of Vitamin and Nutrition Research 54, 257261.
Korpela, H, Nuutinen, LS & Kumpulainen, J (1989) Low serum selenium and glutathione peroxidase activity in patients receiving short-term total parenteral nutrition. International Journal of Vitamin and Nutrition Research 59, 8084.
Koranova, V, Skodova, Z, Dedina, J, Valenta, Z, , Parizek, Pisa, Z & Styblo, M (1993) Serum selenium in adult Czechoslovakia (Central Bohemia) population. Biological Trace Elements Research 37, 91100.
Köse, K, Dogan, P, Kardas, Y & Saraymen, R (1996) Plasma selenium levels in rheumatoid arthritis. Biological Trace Elements Research 53, 5156.
Kotrebai, M, Birringer, M, Tyson, JH, Block, E & Uden, PC (2000 a) Selenium speciation in enriched and natural samples by HPLC–ICP–MS and HPLC–ESI–MS with perfluorinated carboxylic acid ion-pairing agents. Analyst 125, 7178.
Kotrebai, M, Tyson, JH, Block, E & Uden, PC (2000 b) High-performance liquid chromatography of selenium compounds utilizing perfluorinated carboxylic acid ion-pairing agents and inductively coupled plasma and electrospray ionization mass spectrometric detection. Journal of Chromatography 866, 5163.
Koyama, H, Watanabe, C, Satoh, H, Hosokai, H & Tamura, S (1995) Consistent relationship between selenium and apolipoprotein A-II concentrations in the sera of fasting middle-aged male abstainers and regular consumers of alcohol. Biological Trace Elements Research 50, 3342.
KrNmer, K, Look, MP, Chrissafidou, A, Karsten, S & Areads, J (1996) Selen und tumarerkrankugen (Selenium and tumourigenesis. Aktuelle Ernahrungsmedizin 21, 103113.
Krajčovičová-Kudláčková, M, Šimončič, R, Babinska, K, Béderová, A, Brtková, A, Magálová, T & Grančičová, E (1995) Selected vitamins and trace elements in blood of vegetarians. Annals of Nutrition and Metabolism 39, 334339.
Krsnjavi, H, Grgurevic-Batinica, A, Beker, D, Romic, Z & Krsnjavi, A (1992) Selenium and fertility in men. Trace Elements in Medicine 9, 107108.
Kurahashi, K, Inoue, S, Yonekura, S, Shimoshi, Y & Toei, K (1980) Determination of selenium in human blood by gas chromatography with electron-capture detection. Analyst 105, 690695.
Kvíčala, V, Zamrazil, H & čermák, J (1994) Levels of some trace elements in serum of Prague inhabitants measured by INAA. Biological Trace Elements Research 43–45, 497502.
Kvíčala, V, , Zamrazil, če[rcaron]ovska, J, Bedná[rcaron], J & Janda, J (1995) Evaluation of selenium supply and status of inhabitants of three selected rural and urban regions of the Czech Republic. Biological Trace Elements Research 47, 365375.
Kyriakopoulos, A, Rothlein, D, Pfeifer, H, Gessner, H, Behne, (1998) Selenium-containing compounds in baker's yeast (Saccharomycese cerevisiae). In Mengen-Spurenelem., Arbeitstag 18th pp. 740745 [Anke, M, editor]. Leipsig: Verlag Harald Schubert.
Lag, J (1998) Germedical aspects of selenium: Norwegian investigations. Journal of Environmental Pathology, Toxicology and Oncology 17, 229232.
Lahermo, P, Alfthan, G & Wang, D (1998) Selenium and arsenic in the environment in Finland. Journal of Environmental Pathology, Toxicology and Oncology 17, 205216.
Lal, M, Joseph, D, Choudhury, KK, Bajpai, HN, Gauba, I, Lokeshwar, MR & Wagle, CS (1991) Studies of blood lead levels in children by proton-induced X-ray emission (PIXE). Science of the Total Environment 103, 209214.
Lamand, M, Tressol, JC & Bellanger, J (1994) The mineral and trace element composition in French food items and intake levels in France. Journal of Trace Elements and Electrolytes in Health and Disease 8, 195202.
Lane, HW, Barroso, AO, Dudrick, SJ, Englert, DA, MacFadyen, BV (1982) Selenium status of seven IVH patients. In Trace Element Metabolism in Man and Animals, pp. 3033 [McHowell, J & White, CL, editors]. New York, NY: Springer-Verlag.
Lane, HW, Lotspeich, CA, Moore, CE, Ballard, J, Dudrick, SJ & Warren, DC (1987) The effect of selenium supplementation on selenium status of patients receiving total parenteral nutrition. Journal of Parenteral and Enteral Nutrition 11, 177182.
Lane, HW, Warren, DC, Martin, E & McCowan, J (1983 a) Selenium status of industrial workers. Nutrition Research 3, 805817.
Lane, HW, Warren, DC, Taylor, BJ & Stool, E (1983 b) Blood selenium and glutathione peroxidase levels and dietary selenium of free-living and institutionalized elderly subjects. Proceedings of the Society for Experimental Biology and Medicine 173, 8795.
Lee, AM, Huel, G, Godin, J, Hellier, G, Sahuquillo, J, Moreau, T & Blot, P (1995) Inter-individual variation of selenium in maternal plasma, cord blood and placenta. Science of the Total Environment 159, 119127.
Lee, GP & Park, KW (1999) Quality improvement of 'Seoul' celery by selenium in the nutrient solution culture. Acta Horticultura 483, 185192.
Lemoyne, M, van Gossum, A, Kurian, R & Jeejeebhoy, KN (1988) Plasma vitamin E, and selenium and breath pentane in home parenteral nutrition patients. American Journal of Clinical Nutrition 48, 13101315.
Levander, OA, Alfthan, G, Arvilommi, H, Gref, CG, Huttunen, JK, Kataja, M, Koivistoinen, P & Pikkarainen, J (1983) Bioavailability of selenium to Finnish men as assessed by platelet glutathione peroxidase activity and other blood parameters. American Journal of Clinical Nutrition 37, 887897.
Levander, OA & Morris, VC (1984) Dietary selenium levels needed to maintain balance in North American adults consuming self-selected diets. American Journal of Clinical Nutrition 39, 809815.
Levander, OA, Moser, PB & Morris, VC (1987) Dietary selenium intake and selenium concentrations of plasma, erythrocytes, and breast milk in pregnant and postpartum lactating and nonlactating women. American Journal of Clinical Nutrition 46, 694698.
Levander, OA, Sutherland, B, Morris, VC & King, JC (1981) Selenium metabolism in human nutrition. In Selenium in Biology and Medicine pp. 256268 [Spallholz, JE, Martin, JL & , Ganther, editors]. Westport, CN: AVI Publishing Co.
Li, JY, Taylor, PR, Li, B, Blot, WJ, Guo, W, Dawsey, S, Wang, GQ, Yang, CS, Zheng, SF, Gail, M, Li, GY, Liu, B, Tangrea, J, Sun, Y, Liu, F, Fraumeni, F & Zhang, YH (1993) Nutrition intervention trials in Linxian, China. Journal of the National Cancer Institute 85, 14921498.
Lin, TH, Tseng, WC & Cheng, SY (1998) Direct determination of selenium in human blood plasma and seminal plasma by graphite furnace atomic absorption spectrophotometry and clinical application. Biological Trace Elements Research 64, 133149.
Liou, JJ, Chen, WL, Chen, RLC & Yang, JPW (1998) Screening and cultivation of a yeast strain with high organoselenium yields. Taiwan Tangy Yangjiuso Yanjiu Huibao 162, 5163.
Liu, S (1997) Selenium-containing anticancer beer Faming Sheqing Gongkai Shoumingshu CN, 1,160.079. Cl. C12C5/02.
Liu, BS & Li, SS (1987) Primary study of relationship between endemic selenosis and fluorosis. Selenium in Biology and Medicine vol. B, 708711 [GF Combs, Jr, Spallholz, JE, Levander, OA & Oldfield, JE, editors]. Westport, CN: AVI Publishing Co.
Liu, CH, Lu, ZH, Su, Q & Duan, YQ (1987) Regional selenium deficiency of feeds in China. In Selenium in Biology and Medicine vol. B, pp. 4752 [GF Combs, Jr, Spallholz, JE, Levander, OA & Oldfield, JE, editors]. Westport, CN: AVI Publishing Co.
Lloyd, B, Holt, RS & Delves, HT (1983) The determination of selenium in plasma and whole egg. In Trace Element Analytical Chemistry in Medicine and Biology vol. 2, pp. 11291141 [Brätter, p & Schramel, P, editors]. New York, NY: de Gruyter.
Lloyd, B, Lloyd, RS & Clayton, BE (1983 b) Effect of smoking, alcohol and other factors on the selenium status of a healthy population. Journal of Epidemiology and Community Health 37, 213217.
Lombeck, I, Kasperek, K, Menzel, H (1987) Selenium status of pediatric patients. In Selenium in Biology and Medicine vol. B, pp. 619630 [GF Combs, Jr, Spallholz, JE, Levander, OA & Oldfield, JE, editors]. Westport, CN: AVI Publishing Co.
Lombeck, I, Menzel, H & Frosch, D (1987) Acute selenium poisioning of a 2-year-old child. European Journal of Pediatrics 146, 308312.
Longnecker, MP, Taylor, PR, Levander, OA, Howe, SM, Veillon, C, McAdam, PA, Patterson, KY, Holden, JM, Stampfer, MJ, Morris, JS & Willett, WC (1991) Selenium in diet, blood and toenails in relation to human health in a seleniferous area. American Journal of Clinical Nutrition 53, 12881294.
, JZ, Zhang, BZ & Milner, JA (1994) Dietary selenite modifies glutathione metabolism and 7,12-dimethylbenz(a)anthracene conjugation in rats. Journal of Nutrition 124, 172180.
Lundberg, AC, Åkesson, A & Åkesson, B (1992) Dietary intake and nutritional status in patients with systemic sclerosis. Annals of Rheumatic Diseases 51, 11431148.
Luo, X, Wei, H, Yang, C, Xing, J, Qiao, C, Feng, Y, Liu, J, Liu, Z, Wu, Q, Liu, Y, Stoecker, BJ, Spallholz, JW & Yang, SP (1985) Selenium intake and metabolic balance of 10 men from a low selenium area of China. American Journal of Clinical Nutrition 42, 3137.
Luoma, PV, Korpela, H, Sotaniemi, EA & Kumpaulainen, J (1985) Serum selenium, glutathione peroxidase, lipids, and human liver microsomal enzyme activity. A double-blind controlled trial of selenium supplementation. Biological Trace Elements Research 8, 113121.
Lux, O & Naidoo, D (1995) The assessment of biological variation components of copper, zinc and selenium. Journal of Nutritional Biochemistry 6, 4347.
McAdam, PA, Smith, DK, Feldman, EB & Hames, C (1984) Effect of age, sex and race on selenium status of healthy residents of Augusta, Georgia. Biological Trace Elements Research 6, 39.
McConnell, KP, Broghamer, WL, Blotcky, AJ & Hurt, OJ (1975) Selenium levels in human blood and tissues in health and in disease. Journal of Nutrition 105, 10261031.
McConnell, KP, Jager, RR, Bland, KI & Blotcky, AJ (1980) The relationship of dietary selenium and breast cancer. Journal of Surgery and Oncology 15, 6770.
McCray, CWR & Hurwood, ID (1963) Selenosis in northwestern Queensland associated with a marine cretaceous formation. Queensland Journal of Agricultural Science 20, 475498.
McKenzie, RL, Rea, HM, Thomson, CD & Robinson, MF (1978) Selenium concentration and glutathione peroxidase activity in blood of New Zealand infants and children. American Journal of Clinical Nutrition 31, 14131418.
McOrist, GD & Fardy, JJ (1989) Selenium status in the blood of Australians using neutron activation analysis. Journal of Radioanalytical and Nuclear Chemistry 134, 6572.
MacPherson, A, Barclay, MNI, Scott, R, Yates, RWS (1997) Loss of Canadian wheat imports lowers selenium intake and status of the Scottish population. In Trace Elements in Man and Animals-9, pp. 203205 [Fischer, PWF, L'Abbé, MR, Cockell, KA & Gibson, RS, editors]. Ottawa: NRC Research Press.
Madaric, A, Kadrabova, J & Ginter, A (1994) Selenium concentration in plasma and erythrocytes in a healthy Slovak population. Journal of Trace Elements and Electrolytes in Health and Disease 8, 4347.
Magalova, T, Be'no, I, Brtkova, T, Meki'nova, D, Volkovona, KM, Staruchova, M & Tatara, M (1997) Levels of Cu, Zn, Se and their relation to levels of ceruloplasmin and the activity of antioxidant enzymes. Bratisl Lek Listy 7, 9881011.
Mahalingam, TR, Vijayalakshmi, S, Krishna Prabhu, S, Thiruvengadasami, A, Murthy, KSR, Sen, D, Mathews, CK & Shanmugasundarum, KR (1997) Studies of some trace and minor elements in blood. A survey of the Kalpakkam (India) population Part II: reference values for plasma and red cells, and correlation with coronary risk index. Biological Trace Elements Research 57, 207221.
Maier, KJ, Nelson, CR, Bailey, FC, Klaine, SJ & Knight, AW (1998) Accumulation of selenium in aquatic biota of a watershed treated with seleniferous fertilizer. Bulletin of Environmental Contamination and Toxicology 60, 409416.
MNkelN, AL, NNnto, V & MNkelN Wang, W (1993) The effect of nationwide selenium-enrichment of fertilizers on selenium status of healthy Finnish medical students living in southwestern Finland. Biological Trace Elements Research 36, 121157.
Maksimovíc, ZJ, Djujić, I, Jović, V & RŠumović, M (1992) Selenium deficiency in Yugoslavia. Biological Trace Elements Research 33, 187196.
Maksimovíc, ZJ, Jović, V, Djujić, I & RŠumović, M (1992) Selenium deficiency in Yugoslavia and possible effects on health. Environmental Geochemistry and Health 14, 107111.
Maksimovíc, ZJ, Rsumovic, M, , Jović, Kosanovic, M & Jovanovic, T (1998) Selenium in soil, grass, and human serum in the Zlatobor mountain area (Serbia): geomedical aspects. Journal of Environmental Pathology ,Toxicology and Oncology 17, 221227.
Maksimovíc, Z, Vlimirovic, D, Djujić, I, Radosevic, P, Bukvic, D, Maric, I & RŠumović, M (1995) Selenium status in patients with Balkan Endemic Nephropathy in Serbia. Naucni Skupovi Srpske Akademije Nauka i Umetnosti,Odeljenje prirodno-matematickih nauka 6, 177181.
Mao, WJ, Li, Y, Li, BF & Liu, YH (1997) Study on biological activity of selenium-enriched mussel extract. Chinese Journal of Oceanology and Limonology 15, 304307.
Marchante-Gayon, JM, Sanchez-Uria, JE & Sanz-Medel, A (1996) Serum and tissue selenium contents related to renal disease and colon cancer as determined by electrothermal atomic absorption spectrometry. Journal of Trace Elements in Medicine and Biology 10, 229236.
Marinov, B, Tsachev, K & Koleva, V (1998) The concentration of selenium in the maternal serum in cases of missed abortion. Akush Ginekologia (Sophia) 37, 1516.
Marklund, SL, Repo, H & Koskimies, S (1987) Superoxide dismutase isoenzymes, glutathione peroxidase and selenium in blood from HLA-B27-positive and -negative subjects. Acta Pathologica Microbiologica et Immunologica Scandanavia 95, 107111.
Marzec, Z (1999) Analytical and estimated values of chromium, nickel and selenium intakes with adult daily food rations. Bromatologi Chemicale Toksykologi 32, 185189.
Masiak, M & Herzyk, D (1984) Behaviour of microelements in lung cancer patients. Fresenius Z. Analytical Chemistry 317, 661662.
Mask, G & Lane, HW (1993) Selected measures of selenium status in full-term and pre-term neonates and their mothers and non-pregnant women. Nutrition Research 13, 901911.
Matsuda, A, Kimura, M & Itokawa, Y (1997) Selenium level and glutathione peroxidase activity in plasma, erythrocytes and platelets of healthy Japanese volunteers. Journal of Nutritional Science and Vitaminology 43, 497504.
Maxia, V, Meloni, S, Rollier, MA, Brandone, A, Patwardhan, VN, Waslien, CI & El Shami, S (1972) Selenium and chromium assay in Egyptian foods and in blood of Egyptian children by activation analysis. Nuclear Activation Techniques in the Life Sciences, pp. 527550, ViennaInternational Atomic Energy Agency.
Mazzella, GL, Sinfurianai, E, Savoldi, F, Allagrine, M, Lanzola, E & Scelsi, R (1983) Blood cells glutathione peroxidase activity and selenium in multiple sclerosis. Experimental Neurology 22, 442446.
Meissner, D (1997) Reference values for blood and serum selenium in the Dresden area. Medicine Klinische 92 Suppl. 3, 4142.
Meltzer, HM, Bibow, K, Paulsen, IT, Mundal, H, Norheim, G & Holm, H (1993) Different bioavailability in humans of wheat and fish selenium as measured by blood platelet response to increased dietary Se. Biological Trace Elements Research 36, 229241.
Meltzer, HM & Huang, E (1995) Oral intake of selenium has no effect on the serum concentrations of growth hormone, insulin-like growth factor-1, insulin-like growth factor-binding proteins 1 and 3 in healthy women. European Journal of Clinical Biochemistry 33, 411415.
Menditto, A, Chiodo, F, Giampaoli, S & Morisi, G (1995) Association of serum selenium with selected cardiovascular risk factors. Microchemical Journal 51, 170180.
Menkes, MS, Comstock, GW, Vuilleumier, JP, Helsing, KJ, Rider, AA & Brookmeyer, R (1986) Serum beta-carotene, vitamin, A and, E, selenium and the risk of lung cancer. New England Journal of Medicine 315, 12501254.
Michaelsson, G, Berne, B, Calmark, B & Strand, A (1989) Selenium in whole blood and plasma is decreased in patients with moderate and severe psoriasis. Acta Dermatologica et Venerologica 69, 2934.
Mihailovic, M, Lindberg, P, Janovic, I & Antic, D (1992) Selenium status of patients with Balkan endemic nephropathy. Biological Trace Elements Research 33, 771777.
Mikac-Dević, ZJ, Vukelić, N & Kljaić, J (1992) Serum selenium level in patients with colorectal cancer. Biological Trace Elements Research 33, 8794.
Miller, L, Mills, BJ, Blotcky, AJ & Lindeman, RD (1983) Red blood cell and serum selenium concentrations as influenced by age and selected diseases. Journal of the American College of Nutrition 4, 331341.
Milly, K, Wit, L, Diskin, C & Tulley, R (1992) Selenium in renal failure patients. Nephron 61, 139144.
Monget, AL, Galan, P, Preziosi, P, Keller, H, Bourgeois, C, Arnaud, J, Favier, A & Hercberg, S (1996) Micronutrient status in elderly people. Geriatrie/Min. Vit. Aux Network. International Journal of Vitamin and Nutrition Research 66, 7176.
Moreno, MA, Marin, C, Vinagre, F & Ostapczuk, P (1999) Trace element levels in whole blood samples from residents of the city of Badajoz, Spain. Science of the Total Environment 229, 209215.
Moore, JA, Noiva, R & Wells, IC (1984) Selenium concentration in plasma of patients with arteriographically defined coronary atherosclerosis. Clinical Chemistry 30, 11711173.
Morisi, G, Patriarca, M & Menotti, A (1988) Improved determination of selenium in serum by Zeeman atomic absorption spectrometry. Clinical Chemistry 34, 127130.
Morris, JS, Stampfer, MJ & Willett, W (1983) Dietary selenium in humans. Toenails as an indicator. Biological Trace Elements Research 5, 529537.
Mosulishvili, LM, Shonia, NI, Ginturi, EN, Efremova, EY & Kharabadze, NE (1985) INAA results for metal traces in human whole blood. Frequency and age characteristics of the distribution. Journal of Radioanalytical and Nuclear Chemistry 88, 121134.
Munz, B, Frank, S, Hubner, G, Olsen, E & Werner, S (1997) A novel type of glutathione peroxidase: expression and regulation during wound repair. Biochemical Journal 326, 579585.
Murphy, C, Golden, B, Ramdath, D, Golden, M (1988) Selenium status during recovery from malnutrition: Effect of selenium supplementation. In Trace Element Metabolism in Man and Animals, vol. 6, pp. 1114 [LS, Hurley, CL, Keen, B, Lönnerdal & RB, Rucker, editors]. New York, NY: Plenum Press.
Mutanen, M (1984) Dietary intake and sources of selenium in young Finnish women Human Nutrition: Applied Nutrition 38A, 265269.
Mutanen, M, Viita, L & MykkNnen, H (1989) Selenium supplementation does not alter platelet activation in subjects with normal selenium status. International Journal of Vitamin and Nutrition Research 59, 309313.
Nakamura, H, Kudo, H, Muramatsu, H, Masago, K, Murakami, Y (1980) Activation analysis of trace elements in the human blood serum of some specific diseases. In Trace Element Analytical Chemistry in Medicine and Biology, pp. 365380 [Brätter, P & Schramel, P, editors]. New York, NY: de Gruyter.
National Research Council (1983) Selenium in Nutrition, revised ed., p. 24. Washington, DCNational Academy Press.
Navarro-Alarcon, M, De, LaSerrana, HL, Perez-Valero, V & Lopez-Martinez, C (1998) Serum selenium levels as indicators of body status in cancer patients and their relationships with other nutritional and biochemical markers. Science of the Total Environment 212, 195202.
Navarro-Alarcon, M, Lopez, G, De, LaSerrana, HL, Perez-Valero, V & Lopez-Martinez, C (1999) Serum and urine selenium concentrations as indicators of body status in patients with diabetes mellitus. Science of the Total Environment 228, 7985.
Nève, J (1995) Human selenium supplementation as assessed by changes in blood selenium concentration and glutathione peroxidase activity. Journal of Trace Elements in Medicine and Biology 9, 6573.
Nève, J, Chamart, S, van Erum, S, Vertongen, F, Dramaix, M (1988 a) Selenium status in humans as investigated by the effects of supplementation with Se-enriched yeast tablets. Selenium in Medicine and Biology pp. 315320 [J, Neève & A, Favier, editors]. New York, NY: de Gruyter.
Nève, J, Molle, L, Hanocq, M, Sinet, PM & van Geffel, R (1983 a) Erythrocyte and plasma trace element levels in clinical assessments. Zinc, copper and selenium in normals and patients with Down's syndrome and cystic fibrosis. Biological Trace Elements Research 5, 7579.
Nève, J, Sinet, PM, Molle, L & Nicolle, A (1983 b) Selenium, zinc and copper in Down's syndrome (trisomy 21): blood and relations with glutathione peroxidase and superoxide dismutase. Clinica Chimica Acta 133, 209214.
Nève, J, Vertongen, F & Capel, P (1988 b) Selenium supplementation in healthy Belgian adults: response in platelet glutathione peroxidase activity and other blood indices. American Journal of Clinical Nutrition 48, 139143.
Nève, J, Vertongen, F, Thonnart, N, Carpentier, YA (1984) Assessment of selenium status in patients receiving long-term total parenteral nutrition. In Trace Element Analytical Chemistry in Medicine and Biology vol. 3, pp. 139149 [Brätter, P & Schramel, P, editors]. New York, NY: de Gruyter.
Noble, RM & Barry, GA (1982) Survey of selenium concentrations in wheat, sorghum and soybean grains, prepared poultry feeds and feed ingredients from Queensland. Queensland Journal of Agricultural and Animal Sciences 39, 18.
Nomura, AMY, Lee, J, Stemmermann, GN & Combs, GF (2000) Serum selenium and subsequent risk of prostate cancer. Cancer Prevention Biomarkers 9, 883887.
Oldfield, JE (1999) Selenium World Atlas, BrusselsSelenium Tellurium Development Association.
Olivieri, O, Girelli, D, Azzini, M, Stanzial, AM, Russo, C, Ferroni, M & Corrocher, R (1995) Low selenium status in the elderly influences thyroid hormones. Clinical Science 89, 637642.
Olivieri, O, Stanzial, A, Girelli, D, Trevisan, M, Guarini, P, Terzi, M, Caffi, S, Fontana, F, Casaril, M, Ferrari, S & Corrocher, R (1994) Selenium status, fatty acids, vitamins A and E, and aging: the Nove Study. American Journal of Clinical Nutrition 60, 510517.
Olmsted, L, Schrauzer, GN, Flores-Arce, M & Dowd, J (1989) Selenium supplementation of symptomatic human immunodeficiency virus infected patients. Biological Trace Elements Research 20, 5965.
Ojo, OJ, Oluwolfe, AF, Durosinmi, AM, Ogunsola, OJ, Akanle, OA & Spyrou, NM (1994) Baseline levels of elemental concentrations in whole blood, plasma and erythrocytes of Nigerian subjects. Biological Trace Elements Research 46, 461469.
Orack, H & Yanavdag, R (1996) Selenium content of milk and milk products of Turkey. Part I. Chimica Acta Turcica 24, 239243.
Oster, O, Drexler, M, Schenk, J, Meinertz, T, Kasper, W, Schuster, CJ & Prellwitz, W (1986) The serum selenium concentration of patients with acute myocardial infarction. Annals of Clinical Research 18, 3642.
Oster, O & Prellwitz, W (1982) A methodological comparison of hydride and carbon furnace atomic absorption spectroscopy for the determination of selenium. Clinica Chimica Acta 124, 277291.
Oster, O & Prellwitz, W (1990 a) Selenium and cardiovascular disease. Biological Trace Elements Research 24, 91103.
Oster, O & Prellwitz, W (1990 b) The renal excretion of selenium. Biological Trace Elements Research 24, 119146.
Oster, O, Prellwitz, W, Kasper, W & Meinertz, T (1983) Congestive cardiomyopathy and the selenium content of plasma. Clinica Chimica Acta 128, 125132.
Oster, O, Schmiedel, G & Prellwitz, W (1988 a) The organ distribution of selenium in German adults. Biological Trace Elements Research 15, 2345.
Oster, O, Schmiedel, G & Prellwitz, W (1988 b) Correlations of blood selenium with hematological parameters in West German adults. Biological Trace Elements Research 15, 4781.
Overvad, K, Wang, D, Olsen, J, Allen, D, Thorling, E, Bulbrook, R & Hayward, J (1991) Selenium in human mammary carcinogenesis: a case-control study. European Journal of Cancer 27, 900902.
Ozata, M, Salik, M, Aydin, A, Sayin, S, Oktenu, C, Beyhan, Z, Isimer, A & Ozdemir, IC (1999) Iodine and zinc, but not selenium and copper, deficiency exists in a male Turkish population with endemic goiter. Biological Trace Elements Research 69, 211216.
Panel on Dietary Antioxidants and Related Compounds (2000) Dietary Reference Intakes for Vitamin, C, Vitamin, E, Selenium and Beta-Carotene and other Carotenoids, Washington, DCNational Academy Press.
Pawlowicz, Z, Zachara, BA, Trafikowska, U, Maciag, A, Marchaluk, E & Nowicki, A (1991) Blood selenium concentrations and glutathione peroxidase activities in patients with breast cancer and with advanced gastrointestinal cancer. Journal of Trace Elements and Electrolytes in Health and Disease 5, 275277.
Pearn, J & McCay, CRW (1979) Blood selenium in chronic spinal muscular atrophy. Journal of Neurological Science 42, 199202.
Peleg, I, Morris, S & Hames, CG (1985) Is serum selenium a risk factor for cancer?. Medical Oncology and Tumor Pharmacotherapy 2, 157163.
Peng, A, Wang, WH, Wang, CX, Wang, ZJ, Rui, HF, Wang, WZ & Yang, ZW (1999) The role of humic substances in drinking water in Kaschin-Beck diesease in China. Environmental Health Perspectives 107, 293296.
Peng, A, Xu, Y, Lu, JH & Wang, ZJ (2000) Study on the dose–effect relationship of selenite with the growth of wheat. Biological Trace Elements Research 76, 175181.
Peretz, A, Nève, J, Desmedt, J, Duchateau, J, Dramaix, M & Famaey, JP (1991) Lymphocyte response is enhanced by supplementation of elderly subjects with selenium-enriched yeast. American Journal of Clinical Nutrition 53, 13231328.
Peretz, A, Nève, J, Fontaine, J, Vertongen, F, Famaey, JP (1988) Effects of corticosteroid treatment on selenium status in man and animal. In Selenium in Medicine and Biology, pp. 9396 [Neéve, j & Favier, A, editors]. New York, NY: de Gruyter.
Perona, G, Guidi, GC, Piga, A, Cellerino, R, Milani, G, Colautti, B, Moschini, G & Stievano, BM (1979) Neonatal erythrocyte glutathione peroxidase deficiency as a consequence of selenium imbalance during pregnancy. British Journal of Haematology 42, 567574.
Piccinini, L, Borella, P, Bargellini, A, Medici, CI & Zoboli, A (1996) A case-control study on selenium, zinc and copper in plasma and hair of subjects affected by breast and lung cancer. Biological Trace Elements Research 51, 2329.
Pleban, PA, Munyani, A & Beachum, J (1982) Determination of selenium concentration and glutathione peroxidase activity in plasma and erythrocytes. Clinical Chemistry 28, 311316.
Poirier, KA (1994) Summary of the derivation of the reference dose for selenium. In Risk Assessment of Essential Elements, pp. 157166 [Mertz, W, Abernathy, CO & Olin, SS, editors]. Washington, DC: ILSI Press.
Prieto, MA, Naranjo, CC, Lui, GP, de la Cruz, GM, de la Fe Napoles, C & Mestre, PF (1994) Determination of selenium in blood and serum of patients with epidemical neuritis by ETAAS. Quimica Analitica 13, 182186.
Primm, P, Anderson, HD & Morris, JS (1979) The effects of dialysis time on selenium loss from human blood sera. Transactions of the Missouri Academy of Sciences 23, 117124.
Pucheu, S, Coudray, C, Vanzetto, G, Favier, A, Machecourt, J & de Leiris, J (1995) Time-course of changes in plasma levels of trace elements after thrombolysis during the acute phase of myocardial infarction in humans. Biological Trace Elements Research 47, 171181.
Raines, DA, Kinsara, AJ, Fawzy, ME, Vasudevan, S, Mohamed, GE, Legayada, ES, Al-Rawithi, S & Al-Yazigi, A (1999) Plasma and urinary selenium in Saudi Arabian patients with dilated cardiomyopathy. Biological Trace Elements Research 69, 5968.
Ravaglia, G, Forti, P, Mailoli, F, Bastagli, L, Facchini, A, Mariani, E, Savarino, L, Sassi, S, Cucinotta, D & Lenaz, G (2000) Effect of micronutrient status on natural killer cell immune function in healthy, free-living subjects aged >90 y. American Journal of Clinical Nutrition 71, 590598.
Rayman, MP (1997) Dietary selenium: time to act. British Medical Journal (Clinical Research Edition) 314, 387388.
Rayman, MP (2000) The importance of selenium to human health. Lancet 356, 233241.
Rayman, MP, Abou-Shakra, FA, Ward, NI & Redman, CWG (1996) Comparison of selenium levels in pre-eclamptic and normal pregnancies. Biological Trace Elements Research 55, 920.
Rea, HM, Thomson, CD, Campbell, DR & Robinson, MF (1979) Relation between erythrocyte selenium concentrations and glutathione peroxidase (EC 1.11.1.9) activities of new Zealand residents and visitors to New Zealand British Journal of Nutrition 42, 201208.
Reilly, C (1998) Selenium: a new entrant into the functional food arena. Trends in Food Science and Technology 9, 114118.
Reinhold, U, Blitz, H, Bayer, W & Schmidt, KH (1989) Serum selenium levels in patients with malignant melanoma. Acta Dermatologica et Venereologica (Stockholm) 69, 132136.
Ribalta, J, Reyes, H, Hernandez, I, Fuentes, O, Baez, M, Gonzales, M & Palma, J (1995) Can a selenium deficiency affect the pathogenesis of cholestasis in pregnancy?. Gastroenterology and Hepatology 18, 114120.
Richard, MJ, Arnaud, J, Koukay, N, Favier, A, Jurkovits, C, Dechelette, E, Hachache, T, Meftahi, H, Foret, M, Laporte, DF (1988) Lipid peroxidation, relationship with selenium and glutathione peroxidase activities in patients with chronic renal failure. In Selenium in Medicine and Biology, pp. 283288 [Nève, J & Favier, A, editors]. New York, NY: de Gruyter.
Ringstad, J, Kildebo, S & Thamassen, Y (1993 a) Serum selenium, copper, and zinc concentrations in Crohn's disease and ulterative colitis. Scandinavian Journal of Gastroenterology 28, 605608.
Ringstad, J, Knutsen, SF, Nilssen, OR & Thomassen, Y (1993 b) A comparative study of serum selenium and vitamin E levels in a population of male risk drinkers and abstainers: A population-based matched-pair study. Biological Trace Elements Research 36, 6571.
Robberecht, HJ & Deelstra, HA (1994) Factors influencing blood selenium concentrations: a literature review. Journal of Trace Elements and Electrolytes in Health and Disease 8, 129143.
Robberecht, HJ, Hendrix, P, Van Cauwenbergh, R & Deelstra, HA (1994) Actual daily dietary intake of selenium in Belgium, using duplicate portion sampling. Zeitschrift fur Lebensmittel-Untersuchung und Forschung 199, 251254.
Robinson, MF, Campbell, DR, Stewart, RDH, Rea, HM, Thomson, CD, Snow, PG & Squires, IHW (1981) Effect of daily supplements of selenium on patients with muscular complaints in Otago and Canterbury. New Zealand Medical Journal 93, 289292.
Robinson, MF, Campbell, DR, Sutherland, HF, Herbison, GP, Paulin, JM & Simpson, FO (1983) Selenium and risk factors for cardiovascular disease in New Zealand. New Zealand Journal of Medicine 96, 755762.
Robinson, MF, Godfrey, PJ, Thomson, CD, Rea, HM & van Rij, AM (1979) Blood selenium and glutathione peroxidase activity in normal subjects and in surgical patients with and without cancer in New Zealand. American Journal of Clinical Nutrition 32, 14771485.
Robinson, MF, Thomson, CD (1987) Status of the food supply and residents of New Zealand. In Selenium in Biology and Medicine, vol. B, pp. 631644 [Combs, GF Jr, Spallholz, JE, Levander, OA and Oldfield, JE, editors]. Westport, CN: AVI Publishing Co.
Robinson, MF, Thomson, CD & Huemmer, PK (1985) Effect of a megadose of ascorbic acid, a meal and orange juice on the absorption of selenium as sodium selenite. New Zealand Medical Journal 98, 626628.
Robinson, MF, Thomson, CD, Jenkins, P, Luzhen, G & Whanger, PD (1997) Long-term supplementation with selenate and selenomethionine: urinary excretion by New Zealand women British Journal of Nutrition 77, 551563.
Robinson, MF, Thomson, CD, Ong, LK & Huemmer, P (1983 b) Effects of supplementation with high-selenium yeast wheat bread on glutathione peroxidase and related enzymes in women Proceedings of the Nutrition Society 43, 17A.
Rosenfeld, I & Beath, OA (1964) Selenium: Geobotany, Biochemistry, Toxicology and Nutrition, New York, NYAcademic Press.
Rotruck, JT, Ganther, HE, Swanson, AB, Hafeman, DG & Hoekstra, WG (1972) Selenium: Biochemical role as a component of glutathione peroxidase. Science 179, 588590.
Rudolph, N & Wong, SL (1978) Selenium and glutathione peroxidase activity in maternal and cord plasma and red cells. Pediatric Research 12, 789792.
Rukgauer, M, Klein, J & Kruse-Jarres, JD (1997) Reference values for the trace elements copper, manganese, selenium and zinc in the serum/plasma of children, adolescents and adults. Journal of Trace Elements in Medicine and Biology 11, 9298.
Saeed, K, Thomassen, Y & Langmyr, FJ (1979) Direct electrothermal atomic absorption spectrometric determination of selenium in serum. Analytica Chimica Acta 110, 285289.
Saint-Georges, M, d'Auzac, CL, Bonnefont, D, Bourely, B, Jaudon, MC, Galli, A (1988) Implication of selenium and glutathione peroxidase deficiency in the pathology of hemodialyzed patients. In Selenium in Medicine and Biology pp. 293296 [Nève, J & Favier, A, editors]. New York, NY: de Gruyter.
Salbe, AD, Hill, CH, Veillon, C, Howe, SM, Longnecker, MR, Taylor, PR & Levander, OA (1993) Relationship between serum somatomedin C levels and tissue selenium content among adults living in a seleniferous area. Nutrition Research 13, 399405.
Salonen, JT, Alfthan, G, Huttunen, JK, Pikkarainen, J & Puska, P (1982) Association between cardiovascular death and myocardial infarction and serum selenium as a matched-pair longitudinal study. Lancet 2, 175179.
Salonen, T, Halme, M, Sarna, S, Westermarck, T, Nordberg, UR, Bayer, W (1988) Selenium status improved among elderly due to selenium-enrichment of fertilizers in Finland. In Trace Element Metabolism in Man and Animals vol. 6, pp. 1920 [Hurley, LS, Keen, CL, Lönnerdal, B & Rucker, RB, editors]. New York, NY: Plenum Press.
Salvini, S, Hennekens, CH, Morris, JS, Willett, WC & Stampfer, MJ (1995) Plasma levels of the antioxidant selenium and risk of myocardial infarction among US physicians. American Journal of Cardiology 76, 12181221.
Samir, M & El-Awady, MY (1998) Serum selenium levels in multinodal goiter. Clinical Otolaryngology 23, 512514.
Sanchez-Ocampo, A, Torres-Perez, J & Jimeniz-Reyes, M (1996) Selenium levels in the serum of workers in a rubber tire repair shop. American Industrial Hygiene Association Journal 57, 7275.
Saraymen, R, Soylak, M, Elci, L & Dogan, M (1997) Blood serum selenium level of adults living in the province of Kayseri-Turkiye. Fresenius Environmental Bulletin 6, 694698.
Schramel, P, Hasse, S & Ovcar-Pavlu, J (1988) Selenium, cadmium, lead and mercury concentrations in human breast milk, in placenta, maternal blood and the blood of the newborn. Biological Trace Elements Research 15, 111124.
Schrauzer, GN, Molenaar, T, Mead, S, Luehn, K, Yamamoto, H & Araki, E (1985) Selenium in the blood of Japanese and American women with and without breast cancer and fibrocystic disease. Japanese Journal of Cancer Research (Gann) 76, 374377.
Schrauzer, GN, Rhead, WJ & Evans, GA (1973) Selenium and cancer: Chemical interpretation of a plasma 'cancer test'. Bioinorganic Chemistry 2, 329340.
Schrauzer, GN & White, DA (1978) Selenium in human nutrition: Dietary intakes and effects of supplementation. Bioinorganic Chemistry 8, 303318.
Schubert, A, Holden, JM & Wolf, WR (1987) Selenium content of a core group of foods based on a critical evaluation of published analytical data. Journal of the American Dietetic Association 87, 285292.
Schwarz, K, Bieri, JG, Briggs, GM & Scott, ML (1957) Prevention of exudative diathesis in chicks by factor 3 and selenium. Proceedings of the Society for Experimental Biology and Medicine 95, 621626.
Schwarz, K & Foltz, CM (1957) Selenium as an integral part of factor 3 against dietary necrotic liver degeneration. Journal of the American Chemical Society 79, 32923293.
Scieszka, M, Danch, A, Machalski, M & Drozdz, M (1997) Plasma selenium concentration in patients with stomach and colon cancer in the Upper Silesia. Neoplasma 44, 395397.
Scott, R, MacPherson, A, Yates, R (1997) Selenium supplementation in sub-fertile human males. In Trace Elements in Man and Animals-9 pp. 458459 [Fischer, PWF, L'Abbé, MR, Cockell, KA & Gibson, RS, editors]. Ottawa: NRC Research Press.
Segal, I, Gut, A, Schofield, D, Shiel, N & Braganza, JM (1995) Micronutrient antioxidant status in black South Africans with chronic pancreatitis: opportunity for prophylaxis. Clinica Chimica Acta 239, 7179.
Sekulovic, D, Maksimovic, S, Jakovljevic, M, Kresovic, M & Mihajlov, M (1996) Application of Se-fertilizers in cultivated mint and chamomile production in order to improve their pharmacological properties. Journal of Science and Agricultural Research 57, 9399.
Sesama, G, Baj, A, Toffoletto, F, Sega, R & Ghezzi, L (1992) Plasma selenium levels of the general population of an area of northern Italy. Science of the Total Environment 120, 97102.
Shamberger, RJ, Rukovena, E, Longfield, AK, Tytko, SA, Deadbar, S & Willis, CE (1973) Antioxidants and cancer: I. Selenium in the blood of normal and cancer patients. Journal of the National Cancer Institute 50, 863870.
Shin, WS, Hong, SI, Jung, MR, Kim, JH & Na, HB (1991) The study on concentration of serum selenium in patients with hepatoma. Korean Journal of Nutrition 24, 506515.
Shortt, CT, Duthie, GC, Robertson, JD, Morrice, PC, Nicol, F & Arthur, JR (1997) Selenium status of a group of Scottish adults. European Journal of Clinical Nutrition 51, 400404.
Shrift, A (1964) selenium cycle in nature?. Nature 201, 13041305.
Sima, A & Pfannhauser, W (1998) Selenium levels in foods produced in Austria. In Mengen-Spurenelem., Arbeitstag 18th pp. 197204 [Anke, M, editors]. Leipsig: Verlag Harald Schubert.
Sinet, PM, Nève, J, Nicole, A & Molle, L (1984) Low plasma selenium in Down's syndrome (trisomy 21). Acta Paediatrica Scandinavica 73, 275277.
Sippola, J (1979) Selenium in content of soil and timothy (Phleum pratense) in Finland. Annals of Agriculture in Finland 18, 182187.
Slejkovec, Z, van Elteren, JT, Wordoniecka, UD, Kroon, KJ, Falnoga, I & Byrne, AR (2000) Preliminary study on the determination of selenium compounds in some selenium-accumulating mushrooms. Biological Trace Elements Research 75, 139155.
Sluis, KB, Darlow, BA, George, PM, Mogridge, N, Dolamore, BA & Winterbourn, CC (1992) Selenium and glutathione peroxidase levels in premature infants in a low selenium community (Christchurch, New Zealand). Pediatric Research 32, 189194.
Smith, AM, Chang, MPH & Medeiros, LC (2000) Generational differences in selenium status of women. Biological Trace Elements Research 75, 157165.
Smith, JC, Lewis, S, Holbrook, S, Seidel, K & Rose, K (1987) Effect of heparin and citrate on measured concentrations of various analytes in plasma. Clinical Chemistry 33, 814816.
Snook, JT, Palmquist, DL, Moxon, AL, Cantor, AH & Vivian, WM (1983) Selenium status of a rural (predominantly Amish) community living in a low-selenium area. American Journal of Clinical Nutrition 38, 620630.
Squali, H, Arnaud, J, Richard, MJ, Renversez, JC & Favier, A (1997) Evaluation of oxidative stress and antioxidant defenses in malnourished Moroccan children. Annals of Nutrition and Metabolism 41, 149159.
Srikumar, TS, Johansson, GK, öckerman, PA, Gustafsson, JA & Åkesson, B (1992) Trace element status in healthy subjects switching from a mixed to a lactovegetarian diet for 12 mo. American Journal of Clinical Nutrition 55, 885890.
Stadtman, TC (1996) Selenocysteine. Annual Review of Biochemistry 65, 83100.
Stead, NW, Bishop, SL & Carroll, RM (1984) Selenium (Se) balance in the dependent elderly American Journal of Clinical Nutrition 39, 677.
Stewart, RDH, Griffiths, NM, Thomson, CD & Robinson, MF (1978) Quantitative selenium metabolism in normal New Zealand women British Journal of Nutrition 40, 4554.
Stoewsand, GS, Andrews, JL, Munson, L & Lisk, DJ (1989) Effect of dietary Brussels sprouts with increased selenium content on mammary carcinogenesis in the rat. Cancer Letters 45, 4348.
Stork, A, Jury, WA & Frankenberger, WT (1999) Accelerated volatilization of selenium from different soils. Biological Trace Element Research 69, 217234.
Strain, JJ, Bokje, E, Van't Veer, P, Coulter, J, Stewart, C, Logan, H, Odling-Smee, W, Spence, RAJ & Steele, K (1997) Thyroid hormones and selenium status in breast cancer. Nutrition and Cancer 27, 4852.
Suadicani, P, Hein, HO & Gyntelberg, F (1992) Serum selenium concentation and risk of ischemic heart disease in a prospective cohort study of 3000 males. Atherosclerosis 96, 3342.
Sullivan, JF, Blotcky, AJ, Jetton, MM, Hahn, HKJ & Burch, RE (1979) Serum levels of selenium, calcium, copper, magnesium, manganese and zinc in various human diseases. Journal of Nutrition 109, 14321437.
Sundström, H, Yrjanheikki, E & Kauppila, A (1986) Serum selenium and thromboxane in patients with gynecological cancer. Carcinogenesis 5, 10511052.
Sune, X & Zhou, Y (1997) Selenium-rich vinegar Faming Sheqing Gongkai Shoumingshu.
Suzuki, T, Hongo, T, Ohba, T, Kobayashi, K, Imai, H, Ishida, H & Suzuki, H (1989) The relation of dietary selenium to erythrocyte and plasma selenium concentrations in Japanese college women. Nutrition Research 9, 839848.
Suzuki, T, Imai, H & Kobatashi, K (1988) Dietary intake of selenium in Japanese: an estimation by analyzed and reported values in foodstuffs and cooked dishes. Journal of the Japanese Society of Nutrition and Food Science 41, 91102.
Swaine, DJ (1955) The trace element content of soils. Commonwealth Bureau of Soil Science Technical Committee 48, 1157.
Swanson, CA, Longnecker, MP, Veillon, C, Howve, SM, Levander, OA, Taylor, PR, McAdam, PA, Brown, C, Stampfer, MJ & Willet, WC (1990) Selenium intake, age, gender and smoking in relation to indices of selenium status of adults residing in a seleniferous area. American Journal of Clinical Nutrition 52, 852862.
Tan, JA, Zheng, DZ, Hou, SF, Zhu, WY, Li, RB, Zhu, ZY, Wang, WY (1987) Selenium in ecological and chemicogeography and endemic Keshan and Kaschin-Beck disease in China. In Selenium in Biology and Medicine vol. B, pp. 859876 [GF Combs, Jr, Spallholz, JE, Levander, OA & Oldfield, JE, editors]. Westport, CN: AVI Publishing Co.
Tanner, AR, Bantock, I, Hinks, L, Lloyd, B, Turner, NR & Wright, R (1986) Depressed selenium and vitamin E, levels in an alcoholic population. Possible relationship to hepatic injury through increased lipid peroxidation. Digestive Diseases and Sciences 31, 13071312.
Tarp, U, Hansen, JC & Overvad, K (1986) Blood selenium concentrations during long-term supplementation. Nutrition Research 6, 853855.
Tarp, U, Thorling, EB & Hansen, JC (1990) Longitudinal study of changes in blood selenium among Danish blood bank donors (1974–1988). Nutrition Research 10, 11711176.
Terrier, F, Hida, H, Favier, A & Marconnet, P (1995) Muscle GSH-Px activity after prolonged exercise, training, and selenium supplementation. Biological Trace Elements Research 47, 279285.
Terry, N, Zayed, AM, de Souza, MP & Tarum, AS (2000) Selenium in higher plants. Annual Review of Plant Physiology and Plant Molecular Biology 51, 401432.
Thérond, P, Marchand, M, Biou, D, Demelier, JF, Auzépy, P, Richard, C (1988) Plasma selenium and cardiomyopathy. In Selenium in Medicine and Biology pp. 277279 [J, Nève & A, Favier, editors]. New York, NY: de Gruyter.
Thérond, P, Marchand, M, Biou, D, Demelier, JF, Brion, F, Foucaud, P, Navarro, J (1988) Selenium and vitamin E supplementation in cystic fibrosis. In Selenium in Medicine and Biology pp. 333336 [J, Nève & A, Favier, editors]. New York, NY: de Gruyter.
Thiele, R, Schuffenhauer, M, Winnefled, K, Dawcnski, H, Pleissner, J & Pfeifer, R (1995) Selenium level in patients with acute myocardial infarct and in patients wth severe angina pectoris without myocardial infarct. Medicine Klinische 90 Suppl. 1, 4548.
Thilly, CH, Swennen, B, Bourdoux, P, Ntambue, K, Moreno-Reyes, R, Gillies, J & Vanderpas, JB (1993) The epidemiology of iodine-deficiency disorders in relation to goitrogenic factors and thyroid-stimulating hormone regulation American Journal of Clinical Nutrition 57 Suppl., 267S270S.
Thilly, CH, Vanderpas, JB, Beba, N, Ntambue, K, Contempre, B, Swennen, B, Moreno-Reyes, R, Bourdoux, P & Delange, F (1992) Iodine deficiency, other trace elements, and goitrogenic factors in the etiopathogeny of iodine deficiency disorders. Biological Trace Elements Research 32, 229243.
Thomson, CD, Ong, LK & Robinson, MF (1985) Effects of supplementation with high-selenium wheat bread on selenium, glutathione peroxidase and related enzymes in blood components of New Zealand residents. American Journal of Clinical Nutrition 41, 10151022.
Thomson, CD & Robinson, MF (1986) Urinary and fecal excretions and absorption of a large supplement of selenium: superiority of selenate over selenite. American Journal of Clinical Nutrition 44, 659663.
Thomson, CD & Robinson, MF (1993) Long-term supplementation with selenate and selenomethionine: selenium and glutathione peroxidase (EC 1.11.1.9) in blood components of New Zealand women British Journal of Nutrition 69, 577588.
Thomson, CD & Robinson, MF (1996) The changing selenium status of New Zealanders. European Journal of Clinical Nutrition 50, 107114.
Thomson, CD, Robinson, M, Butler, J & Whanger, P (1993) Long-term supplementation with selenate and selenomethionine: selenium and glutathione peroxidase in blood components of New Zealand residents. British Journal of Nutrition 69, 577588.
Thomson, CD, Robinson, MF, Campbell, DR & Rea, HM (1982) Effect of prolonged supplementation with daily supplements of selenomethionine and sodium selenite on glutathione peroxidase activity in blood of New Zealand residents. American Journal of Clinical Nutrition 36, 2431.
Thomson, CD, Robinson, MF, Whanger, PD (1989) Selenium (Se) and glutathione peroxidase (GSH-Px) in blood components of NZ women during long-term supplementation with selenate or selenomethionine (Semet). In Selenium in Biology and Medicine pp. 254257 [Wendel, A, editor]. New York, NY: Springer-Verlag.
Thomson, CD & Stevens, SM (1988) The absence of adaptive changes in tissue activities of glutathione-S-transferase, superoxide dismutase and catalase following selenium and vitamin, E supplementation in subjects of low selenium status. Biochemistry International 16, 8392.
Thomson, CD, Stevens, SM, van Rij, AM, Wade, CR & Robinson, MF (1988) Selenium and vitamin E supplementation: Activities of glutathione peroxidase in human tissues. American Journal of Clinical Nutrition 48, 316323.
Thorngren, M & Åkesson, B (1987) Effect of dietary fish on plasma selenium and its relation to haemostatic changes in healthy adults. International Journal of Vitamin and Nutrition Research 57, 429435.
Thorling, EB, Overvad, K & Geboers, J (1986) Selenium status in Europe -- Human data a multicenter study. Annals of Clinical Research 18, 37.
Thorling, EB, Overvad, K, Heerfordt, A & Fooldspang, A (1985) Serum selenium in Danish blood bank donors. Biological Trace Elements Research 8, 6573.
Thuluvath, PJ & Triger, DR (1992) Selenium and chronic liver disease. Journal of Haematology 14, 176182.
Thuong, T, Auzépy, P, Blondeau, M & Richard, C (1986 a) Decrease of the serum level of selenium in chronic alcoholics with or without dilated cardiomyopathy. Presse Médicine 15, 693696.
Turan, B, DelilbaŞi, E, Dalay, N, Sert, Ş, Afrasyap, L & Sayal, A (1992) Serum selenium and glutathione-peroxidase activities and their interaction with toxic metals in dialysis and renal transplantation patients. Biological Trace Elements Research 33, 95102.
Tiran, B, Tiran, A, Petck, W, Rossipol, E & Wawschinek, O (1992) Selenium status of healthy children and adults in Styra (Austria) Investigation of a possible undersupply in the Styrian population. Trace Elements in Medicine 9, 7579.
Tolonen, M, Sarna, S, Halme, M, Tuominen, SE, Westermarck, T, Nordberg, UR, Keinonen, M & Schrijver, J (1988) Anti-oxidant supplementation decreases TBA reactants in serum of elderly. Biological Trace Element Research 17, 221228.
Torra, M, Rodamilans, M, Montero, F & Corbella, J (1997) Serum selenium concentration of a healthy northwest Spanish population. Biological Trace Elements Research 58, 127133.
Trelease, SF (1945) Selenium in soils, plants and animals. Soil Science 60, 125132.
Uehara, S, Honjo, K, Hirano, F, Sakai, N, Hirayama, A & Jin, K (1988) Clinical significance of selenium levels in chronic pancreatitis. Journal of Clinical Biochemistry and Nutrition 5, 201207.
United States Department of Agriculture (1999) Nutrient database for standard reference. http://www.nal.usda.gov/fnic/foodcomp/Data/SR13/sr13.html.
United States Environmental Protection Agency (EPA), Integrated Risk Information System (IRIS) (1991) Reference dose (RfD) for Oral Exposure for Selenium. Online: Input pending (verification date 3/27/91). Cincinnati, OH: Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office.
Valentine, JL, Faraju, B & Akashi, K (1988) Selenium and glutathione peroxidase in mothers experiencing sudden infant death syndrome. In Trace Element Metabolism in Man and Animals vol. 6, pp. 1315 [Hurley, LS, Keen, CL, Lönnerdal, B & Rucker, RB, editors]. New York, NY: Plenum Press.
Valentine, JL, Kang, HK & Spivey, GH (1978) Selenium levels in human blood, urine, and hair in response to exposure via drinking water. Environmental Research 17, 347355.
VNlimNki, M, Alfthan, G, Pikkarainen, G, Ylikahri, R & Salaspuro, M (1987) Blood and liver selenium concentrations in patients with liver diseases. Clinica Chimica Acta 166, 171176.
VNlimNki, M, Harju, KJ & Ylikahri, R (1983) Decreased serum selenium in alcoholics -- a consequence of liver dysfunction. Clinica Chimica Acta 13, 291296.
Van Cauwenbergh, R, Robbercht, H, Deelstra, H, Picramenos, D & Kostakopoulos, A (1994) Selenium concentrations in serum of healthy Greek adults. Journal of Trace Elements and Electrolytes in Health and Disease 8, 99109.
Vanderpas, JB, Contrempre, B, Duale, N, Deckx, H, Bebe, N, Longombe, AO, Thilly, CH, Diplock, AT & Dumont, JE (1993) Selenium deficiency mitigates hypothyroxinemia in iodine-deficient subjects. American Journal of Clinical Nutrition 57, 271S275S.
Vanderpas, JB, Contrempre, B, Duale, N, Goosens, W, Bebe, N, Thorpe, R, Ntambue, K, Dumont, J, Thilly, CH & Diplock, AT (1990) Iodine and selenium deficiency associated with cretinism in northern Zaire. American Journal of Clinical Nutrition 57, 271S275S.
van der Torre, H, van Dokkum, W, Schaafsma, G, Wedel, M & Ockhuizen, T (1991) Effects of various levels of selenium in wheat and meat on blood selenium status indices and on selenium balance in Dutch men. British Journal of Nutrition 65, 6980.
van Gossum, A, Closset, P, Noel, E, Cremer, M & Nève, J (1996) Deficiency in antioxidant factors in patients with alcoholic-related chronic pancreatitis. Digestive Diseases and Sciences 41, 12251231.
van Gossum, A & Nève, J (1995) Low selenium status in alcoholic cirrhosis is correlated with aminopyrine breath test. Preliminary effects of selenium supplementation. Biological Trace Elements Research 47, 201207.
van Rij, AM, McKenzie, JM, Thomson, CD & Robinson, MF (1981) Selenium supplementation in total parenteral nutrition. Journal of Parenteral and Enteral Nutrition 5, 120124.
van't Veer, P, van der Weilen, RP, Kok, FJ, Hermus, RJ & Sturmans, F (1990) Selenium in diet, blood and toenails in relation to breast cancer: a case-control study. American Journal of Epidemiology 131, 987994.
Vendeland, SC, Beilstein, MA, Yeh, JY, Ream, W & Whanger, PD (1995) Rat skeletal muscle selenoprotein W: cDNA clone and mRNA modulation by dietary selenium. Proceedings of the National Academy of Sciences of the United States of America 92, 87498753.
Verlinden, M, van Sprundel, M, Van der Auwera, JC & Eylenbosch, WJ (1983) The selenium status of Belgian population groups. I. Healthy adults. Biological Trace Elements Research 5, 103113.
Vernie, L, de Vries, M, Benckhuijsen, C, de Goeij, J & Zegers, C (1983) Selenium levels in blood and plasma, and glutathione peroxidase activity in blood of breast cancer patients during adjuvant treatment with cyclophosphamide, methotrexate and 5-fluorouracil. Cancer Letters 18, 283289.
Vertongen, F, Nève, J, Cauchie, P, Molle, L (1984) Zinc, copper, selenium and glutathione peroxidase in plasma and erythrocytes of Down's sundrome (trisomy 21) patients. Interpretation of some variations. In Trace Element Analytical Chemistry in Medicine and Biology vol. 3, pp. 175181 [Brätter, P & Schramel, P, editors]. New York, NY: de Gruyter.
Vézina, D, Mauffette, F, Roberts, KD & Bleau, B (1996) Selenium-vitamin E, supplementation in infertile men. Effects on semen parameters and micronutrient levels and distribution. Biological Trace Elements Research 53, 6583.
Viegas-Crespo, AM, Nève, J, Monteiro, ML, Amorin, MF, Paulo, OS & Halpern, MJ (1994) Selenium and lipid parameters in plasma of Portuguese subjects. Journal of Trace Elements and Electrolytes in Health and Disease 8, 119–112.
Virtamo, J, Valkeila, E, Alfthan, G, Punsar, S, Huttunen, JK & Karvor, MJ (1987) Serum selenium and risk of cancer. A prospective follow-up of nine years. Cancer 10, 145148.
Waiyaki, B (2000) Status of cadmium, lead and selenium in the soils of selected African countries and perspectives of their effects on human and environmental health. In Soils Groundwater Pollution Remediatic pp. 347374 [Huang, PM, Islander, IK & Lewis, IK, editors]. Boca Raton, FL: Lewis.
Wallaeys, B, Cornelis, R, Mees, L & Lameire, N (1986) Trace elements in patients with renal insufficiency on continuous ambulatory peritoneal dialysis. Acta Physiologica et Toxicologica 59, 435437.
Wang, GY, Zhou, RH, Sun, SZ, Yin, TA, Wang, HZ, You, DQ & Yang, GQ (1979) The difference in blood and hair selenium contents in residents of Keshan disease endemic and non-endemic areas: correlation between blood selenium and hair selenium. Chinese Journal of Preventive Medicine 13, 204209.
Ward, KP, Arthur, JR, Russell, G & Aggett, PJ (1984) Blood selenium content and glutathione peroxidase activity in children with cystic fibrosis, coeliac disease, asthma and epilepsy. European Journal of Pediatrics 142, 2124.
Wasowicz, W, Wolkanin, P, Bednarski, M, Gromadzinska, J, Sklodowska, M & Grzybowska, K (1993) Plasma trace elements (Se, Zn, Cu) concentrations in maternal and umbilical cord blood in Poland. Relation with birth weight, gestational age and parity. Biological Trace Elements Research 38, 205215.
Wasowicz, W & Zachara, BA (1987) Selenium concentrations in the blood and urine of a healthy Polish sub-population. Journal of Clinical Chemistry Clinical Biochemistry 25, 409412.
Watkinson, JH (1974) The selenium status of New Zealanders. New Zealand Medical Journal 80, 202205.
Watkinson, JH (1987) Annual topdressing of pasture with selenate pellets to prevent selenium deficiency in grazing stock: Research and farming practice in New Zealand. In Selenium in Biology and Medicine vol. B, pp. 783792 [GF Combs, Jr, Spallholz, JE, Levander, OA & Oldfield, JE, editors]. Westport, CN: AVI Publishing Co.
Wei, A (1996) Soybean sprout. Zhengzhou Liangshi Xueyuan Xuebao 17, 6770.
Wells, N (1967) Total selenium in top soils, New Zealand Soil Bureau Atlas, maps 89 and 90. WellingtonGovernment Printer.
Wen, Z, Chen, X, Fu, P, Qian, P, Liu, R, Huang, J (1987) Effect of long-term selenium supplementation on the incidence of Keshan disease. In Selenium in Biology and Medicine vol. B, pp. 902904 [GF Combs, Jr, Spallholz, JE, Levander, OA & Oldfield, JE, editors]. Westport, CN: AVI Publishing Co.
Westermarck, T (1977) Selenium content of tissues in Finnish infants and adults with various diseases, and studies on the effects of selenium supplementation in neuronal ceroid lipofuscinosis patients. Acta Pharmacologica et Toxicologica 41, 121128.
Whanger, PD, Beilstein, MA, Thomson, CD, Robinson, MF & Howe, M (1988) Blood selenium and glutathione peroxidase activity of populations in New Zealand, Oregon and South Dakota. FASEB Journal 2, 29963002.
Whanger, PD, Xia, Y & Thomson, CD (1994) Protein technics for selenium speciation in human body fluids. Journal of Trace Elements and Electrolytes in Health and Disease 8, 17.
Wilke, B, Vidailhet, M, Guillemin, C, Favier, A, Ducros, Y, Arnaud, J, Richard, MJ (1988) Plasma and erythrocyte selenium (Se), glutathione peroxidase (GSH-Px), malondialdehyde (MDA) and plasma lipid hydroperoxides (LH) as a function of Se supplementation in 12 treated phenylketonuric (PKU) children. Selenium in Medicine and Biology pp. 337340 [Nève, J & Favier, A, editors]. New York, NY: de Gruyter.
Wikström, J, Westermarck, T & Palo, J (1976) Selenium, vitamin, E, and copper in multiple sclerosis. Acta Neurologica Scandinavica 54, 287290.
Willett, WC, Polk, BF, Morris, JS, Stampfer, MJ, Pressel, S, Rosner, B, Taylor, JO, Schneider, K & Hames, CG (1983) Prediagnostic serum selenium a risk factor for cancer?. Medical Oncology and Tumor Pharmacotherapy 2, 157163.
World Health Organization (1996) Selenium. In Trace Elements in Human Nutrition and Health pp. 105122,GenevaWHO.
Xia, Y, Paio, J, Hill, KE & Burk, RF (1992 a) Biochemical changes in a selenium-deficient population in China. Proceedings of the Fifth International Symposium on Selenium in Biology and Medicine, Vanderbilt University, p. 36 (abstract).
Xia, Y, Zhao, X, Zhu, L & Whanger, PD (1992 b) Distribution of selenium in erythrocytes, plasma and urine of Chinese men of different selenium status. Journal of Nutritional Biochemistry 3, 211216.
Xia, YM, Hill, KE & Burk, RF (1989) Biochemical studies of a selenium-deficient population in China: measurement of selenium, glutathione peroxidase and other antioxidant defense indices in blood. Journal of Nutrition 119, 13181326.
Xian, G, Cai, H, He, Y & Li, C (1997) Study of nutrition of Ca, P, Fe, Zn and Se of old people in Guangzhou city. Guangdong Weiliang Yuansu Kexue 4, 3841.
Xiong, Y, Mo, D, Bi, H, Li, S, Guo, X, Yu, Z, Luo, Y, Feng, J, Zhang, L & Yang, J (1998) Effect of selenium on lesion of articular cartilage fed on T-2 toxin in Chinese mini-pigs with experimental Kaschin-Beck disease. Xi'an Yike Daxue Xuebao 19, 523525.
Xu, B, Chia, SE & Ong, CN (1994) Concentrations of cadmium, lead, selenium and zinc in human blood and seminal plasma. Biological Trace Elements Research 40, 4957.
Xu, GL, Wang, SC, Sun, J, Gu, BQ, Yang, YX, Song, HB, Tan, W, Xua, W, Liang, WS & Zhang, P (1997 a) Role of selenium deficiency in the etiology and pathogenesis of Keshan disease. J Xi'an Medical University 9, 98106.
Xu, GL, Wang, SC, Gu, BQ, Yang, YX, Song, HB, Xue, HL, Liang, WS & Zhang, P (1997 b) Further investigation on the role of selenium deficiency in the aetiology and pathogenesis of Keshan disease. Biomedical and Environmental Science 10, 316326.
Xu, Q, Xu, Y, Liu, Y & Liu, S (1996) Compound low sodium content health table salt. Faming Sheqing Gongkai Shoumingshu (CN, 1,116,505. Cl. A23L1/237).
Xue, TL & Hartikainen, H (2000) Association of antioxidative enzymes with the synergistic effect of selenium and, UV, irradiation in enhancing plant growth. Agriculture and Food Science in Finland 9, 177187.
Yadav, S, Day, JP, Mohan, V, Snehalatha, C & Braganza, JM (1991) Selenium and diabetes in the tropics. Pancreas 6, 528533.
Yamaguchi, T, Chimura, K, Kurokawa, Y, Hamada, M, Inoue, K & Shibuya, N (1992) Selenium concentration and glutathione peroxidase activity in plasma and erythrocytes from human blood. Journal of Clinical Biochemistry Nutrition 12, 4150.
Yang, GQ, Qian, PC, Zhu, LZ, Huang, JH, Liu, SJ, Lu, MD (1987) Human selenium requirements in China. In Selenium in Biology and Medicine vol. A, pp. 589–594 [GF Combs, Jr, Spallholz, JE, Levander, OA & Oldfield, JE (1982) Relation between the distribution of Keshan disease and selenium status. Acta Nutrimentia Sinica 4, 191200.
Yang, GQ, Wang, S, Zhou, R & Sun, S (1983) Endemic selenium intoxication of humans in China. American Journal of Clinical Nutrition 37, 872881.
Yang, GQ, Yin, S, Zhou, R, Gu, L, Yan, B, Liu, Y & Liu, Y (1989 b) Studies of safe maximal daily dietary Se-intake in a seleniferous area in China. Part II Relation between Se-intake and the manifestations of clinical signs and certain biochemical alterations in blood and urine. Journal of Trace Elements and Electrolytes in Health and Disease 3, 123130.
Yang, GQ & Zhou, RH (1994) Further studies on human maximum safe dietary selenium intake and a discussion on some related problems. Journal of Trace Elements and Electrolytes in Health and Disease 8, 159165.
Yang, GQ, Zhou, R, Yin, S, Gu, L, Yan, B, Liu, Y & Li, X (1989 a) Studies of safe maximal daily dietary Se-intake in a seleniferous area in China. Part I Selenium intake and tissue selenium levels of the inhabitants. Journal of Trace Elements and Electrolytes in Health and Disease 3, 7785.
Yoshida, M, Fukunaga, K, Tsuchita, H & Yasumoto, K (1999) An evaluation of the bioavailability of selenium in high-selenium yeast. Journal of Nutritional Science and Vitaminology 45, 119128.
Yoshita, K, Tabata, M, Kimura, R, Miyashita, Y, Hayashi, K, Sagara, T & Nakagawa, H (1998) Relationship between selenium intake and foods intake and nutrients intake in middle-aged men. Eiyogaku Zasshi 56, 19148.
Yu, MW, Horng, IS, Hsu, KH, Chaing, YC, Liaw, YF & Chen, CJ (1999) Plasma selenium levels and risk of hepatocellular carcinoma among men with chronic hepatitis virus infection. American Journal of Epidemiology 150, 367374.
Yu, S, Mao, B, Xiao, P, Yu, W, Wang, Y, Huang, C, Chen, W & Xuan, X (1990) Intervention trial with selenium for the prevention of lung cancer among tin miners in Yunnan, China. A pilot study. Biological Trace Elements Research 24, 105108.
Yu, SY, Zhu, YJ & Li, WG (1997) Protective role of selenium against hepatitis B virus and primary lever cancer in Qidong. Biological Trace Elements Research 56, 117124.
Zachara, BA, Rybakowski, J, Borowska, K, Pilaczycska, E, Zamorski, R, Stefaniak, B (1988) Blood selenium concentration and glutathione peroxidase activity in male patients with alcohol dependence. In Selenium in Medicine and Biology, pp. 269272 [Nève, J & Favier, A, editors]. New York, NY: de Gruyter.
Zachara, BA, Wasowicz, W, Gromadzinska, J, Sklodowska, M & Krasomski, G (1986) Glutathione peroxidase activity, selenium, and lipid peroxide concentrations in blood from a healthy Polish population. I. Maternal and cord blood. Biological Trace Elements Research 10, 175187.
Zachara, BA, Wasowicz, W, Sklodowska, M & Gromadzinska, J (1987) Selenium status, lipid peroxides concentration and glutathione peroxidase activity in the blood of power station and rubber factory workers. Archives in Environmental Health 42, 223229.
Zhou, MH (1990) Influence of selenium on growth, root vigor and seed morphology of rice. Guizhou Journal of Agricultural Science (China) 15, 5759.
Zhuk, LI, Kist, AA, Mikolskaya, IN, Osinskaya, NS, Tillayev, T, Tursunbayev, SI & Agzamova, SV (1988) Elemental blood composition of the inhabitants of Uzbekistan. Journal of Radioanalytical and Nuclear Chemistry 120, 369377.
Zhuk, LI, Mikholskaya, IN, Danilova, EA & Kist, AA (1994) Mapping using human blood composition data. Biological Trace Elements Research 43–45, 371381.
Zima, T, Mestek, O, N'eme'cek, K & Bartova, V (1998) Trace elements in hemodialysis and continuously ambulatory peritoneal dialysis patients. Blood Purification 16, 253260.
Zimmleri, B, Haldimann, M & Siber, R (1998) Selenium status of the Swiss population. Part 3. Changes and its causes. Mitteilungen aus dem Gebiete der Lebensmitteluntersuchung und Hygiene 89, 257293.