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Studies on calcium absorption from milk using a double-label stable isotope technique

  • Susan J. Fairweather-Tait (a1), Amanda Johnson (a1), J. Eagles (a1), Smita Ganatra (a2), H. Kennedy (a3) and M. I. Gurr (a2)
  • DOI:
  • Published online: 01 March 2007

Calcium absorption was measured in ten male volunteers from skimmed milk, Ca-enriched skimmed milk or watercress (Nasturtium officinale) soup. The foods were labelled extrinsically with 30 mg 44Ca. Shortly after consuming the labelled meal, each subject was given an intravenous injection of 3 mg 42ca. Fractional absorption from the oral dose was determined from plasma and urine samples collected 24–72 h later, using fast atom bombardment mass spectrometry to measure isotope ratios. The values for urine and plasma were in good agreement. Mean percentage absorption was 45.5 (SEM 1.9)% from the skimmed milk, 35.7 (SEM 4.7) % from the Ca-enriched milk and 27.4 (SEM 1.9) % from the watercress soup. The effect of consuming 568 ml (1 pint) Ca-enriched milk each day for 4 weeks on the efficiency of absorption of Ca was studied. Although there was no statistically significant difference between Ca absorption before and after the supplementation period, the results were considered to be somewhat inconclusive due to the small number of subjects and wide individual variation in Ca absorption.

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S. J. Birge , W. A. Peck , M. Berman & G. D. Whedon (1969). Study of calcium absorption in man: a kinetic analysis and physiologic model. Journal of Clinical Investigations 48, 17051713.

P. Charley & P. Saltman (1963). Chelation of calcium by lactose: its role in transport mechanisms. Science 139, 12051206.

R. P. Heaney & T. G. Skillman (1971). Calcium metabolism in normal human pregnancy. Journal of Clinical Endocrinology 33, 661669.

L. S. Hillman , E. Tack , D. G. Covell , N. E. Vieira & A. L. Yergey (1988). Measurement of true calcium absorption in premature infants using intravenous 46Ca and oral 44Ca. Pediatric Research 23, 589594.

X. Jiang & D. L. Smith (1987). Quantitation of stable isotopic tracer of calcium by fast atom bombardment mass spectrometry. Analytical Chemistry 59, 25702574.

J. Kocián , I. Skála & K. Bakos (1973). Calcium absorption from milk and lactose-free milk in healthy subjects and patients with lactose intolerance. Digestion 9, 317324.

O. J. Malm (1953). On phosphate and phosphoric acid as dietary factors in the calcium balance of man. Scandinavian Journal of Clinical and Laboratory Investigation 5, 7584.

M. Nelson , G. F. Hague , C. Cooper & V. W. Bunker (1988). Calcium intake in the elderly: validation of a dietary questionnaire. Journal of Human Nutrition and Dietetics 1, 115127.

M. J. Nicar & Y. C. Pak (1985). Calcium bioavailability from calcium carbonate and calcium citrate. Journal of Clinical Endocrinology and Metabolism 61, 391393.

D. A. Norman , J. S. Fordtran , L. J. Brinkley , J. E. Zerwekh , M. J. Nicar , S. M. Strowig & C. Y. C. Pak (1981). Jejunal and ileal adaptation to alterations in dietary calcium. Journal of Clinical Investigation 67, 15991603.

D. L. Smith (1983). Determination of stable isotopes of calcium in biological fluids by fast atom bombardment mass spectrometry. Analytical Chemistry 55, 23912393.

D. L. Smith , C. Atkin & C. Westenfelder (1985). Stable isotopes of calcium as tracers: methodology. Clinica Chimica Acta 146, 97101.

C. M. Weaver , B. R. Martin , D. L. Smith , J. V. Chambers & C. H. Noller (1988). Endogenous labelling of bovine milk with the stable isotope 44Ca. Nutrition Research 8, 11831189.

A. L. Yergey , N. E. Vieira & D. G. Covell (1987). Direct measurement of dietary functional absorption using calcium isotopic tracers. Biomedical and Environmental Mass Spectrometry 14, 603607.

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