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    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.

    Cashman, Kevin D. and Kiely, Mairead 2016. Tackling inadequate vitamin D intakes within the population: fortification of dairy products with vitamin D may not be enough. Endocrine, Vol. 51, Issue. 1, p. 38.

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    Wang, Erica W. Collins, Andrew R. Pang, Marco Y. C. Siu, Parco P. M. Lai, Claudia K. Y. Woo, Jean and Benzie, Iris F. F. 2016. Vitamin D and oxidation-induced DNA damage: is there a connection?. Mutagenesis, Vol. 31, Issue. 6, p. 655.

    Cashman, Kevin D. 2015. Vitamin D: dietary requirements and food fortification as a means of helping achieve adequate vitamin D status. The Journal of Steroid Biochemistry and Molecular Biology, Vol. 148, p. 19.

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    Hoge, Axelle Donneau, Anne-Françoise Streel, Sylvie Kolh, Philippe Chapelle, Jean-Paul Albert, Adelin Cavalier, Etienne and Guillaume, Michèle 2015. Vitamin D deficiency is common among adults in Wallonia (Belgium, 51°30′ North): findings from the Nutrition, Environment and Cardio-Vascular Health study. Nutrition Research, Vol. 35, Issue. 8, p. 716.

    Kiely, M. and Cashman, K. D. 2015. The ODIN project: Development of food-based approaches for prevention of vitamin D deficiency throughout life. Nutrition Bulletin, Vol. 40, Issue. 3, p. 235.

    Alderton, S. 2014. Do we need free vitamins for all babies and young children in the UK?. Nutrition Bulletin, Vol. 39, Issue. 2, p. 187.

    Cashman, Kevin D. 2014. A review of vitamin D status and CVD. Proceedings of the Nutrition Society, Vol. 73, Issue. 01, p. 65.

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    Cashman, K. D. and Kiely, M. 2014. Recommended dietary intakes for vitamin D: where do they come from, what do they achieve and how can we meet them?. Journal of Human Nutrition and Dietetics, Vol. 27, Issue. 5, p. 434.

    Ramankutty, Padmaja de Klerk, Nicholas H Miller, Margaret Fenech, Michael O'Callaghan, Nathan Armstrong, Bruce K and Milne, Elizabeth 2014. Ultraviolet radiation exposure and serum vitamin D levels in young children. Journal of Paediatrics and Child Health, Vol. 50, Issue. 9, p. 713.

    Souberbielle, Jean-Claude 2014. Actualités sur la vitamine D. OCL, Vol. 21, Issue. 3, p. D304.

    Cashman, Kevin D. and Kiely, Mairead 2013. EURRECA—Estimating Vitamin D Requirements for Deriving Dietary Reference Values. Critical Reviews in Food Science and Nutrition, Vol. 53, Issue. 10, p. 1097.

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    Kiely, M 2013. Prevention of vitamin D deficiency during infancy is achieved by a combination of low-dose maternal and infant supplementation. European Journal of Clinical Nutrition, Vol. 67, Issue. 10, p. 1010.

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Towards prevention of vitamin D deficiency and beyond: knowledge gaps and research needs in vitamin D nutrition and public health

  • Kevin D. Cashman (a1) (a2) and Mairead Kiely (a1)
Abstract

The North American Institute of Medicine (IOM) recently published their report on dietary reference intakes (DRI) for Ca and vitamin D. The DRI committee's deliberations underpinning this most comprehensive report on vitamin D nutrition to date benefited hugely from a much expanded knowledge base in vitamin D over the last decade or more. However, since their release, the vitamin D DRI have been the subject of intense controversy, which is largely due to the persistence of fundamental knowledge gaps in vitamin D. These can be identified at the levels of exposure, metabolism, storage, status, dose–response, function and beneficial or adverse health effects, as well as safe and effective application of intake recommendations at the population level through sustainable food-based approaches. The present review provides a brief overview of the approach used by the IOM committee to revise the DRI for vitamin D and to collate from a number of authoritative sources key knowledge gaps in vitamin D nutrition from the public health perspective. A number of research topics are outlined and data requirements within these are identified and mapped to the risk assessment framework used by the DRI committee. While not intended as an exhaustive list, it provides a basis for organising and prioritising research efforts in the area of vitamin D, which may offer a perspective on the major areas in need of attention. It is intended to be of use to researchers, national policy makers, the public health community, industry groups and other relevant stakeholders including funding institutions.

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Copyright
COPYRIGHT: © The Authors 2011
Corresponding author
*Corresponding authors: Professor K. D. Cashman, fax +353 21 4270244, email k.cashman@ucc.ie; Dr M. Kiely, fax +353 21 4270244, email m.kiely@ucc.ie
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British Journal of Nutrition
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