Hostname: page-component-848d4c4894-ndmmz Total loading time: 0 Render date: 2024-05-06T22:03:11.162Z Has data issue: false hasContentIssue false
  • English
  • Français

Vitamin A absorption and metabolism in the chick: response to high dietary intake and to tocopherol

Published online by Cambridge University Press:  09 March 2007

David Sklan
David Sklan
Affiliation:
Faculty of Agriculture, The Hebrew University of Jerusalem, PO Box 12, Rehovot 76-100, Israel
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

1. Absorption of 14C-labelled retinol was determined along the gastrointestinal tract of chicks, using 141Cerium as a non-absorbed reference substance, as influenced by high dietary vitamin A and the addition of tocopherol to the diet.

2. The site of major vitamin A absorption was the proximal small intestine and high intake of vitamin A reduced slightly the percentage over-all absorption.

3. Labelled glucuronides were secreted into the duodenum and were 50–60% reabsorbed in the small intestines. High-vitamin-A intakes enhanced the duodenal flow of retinyl glucuronides.

4. In vitro hepatic retinol esterification and glucuronide production were enhanced in chicks given high dietary vitamin A.

5. Plasma transport and clearance of retinol were enhanced by feeding high levels of vitamin A and further enhanced when tocopherol at high concentrations was present in the diet.

6. Dietary tocopherol had no effect on absorption, increased hepatic vitamin A stores and in vitro retinol esterification, and decreased retinyl glucuronide flows through the duodenum.

Type
Papers on General Nutrition
Information
British Journal of Nutrition , Volume 50 , Issue 2 , September 1983 , pp. 401 - 407
Copyright
Copyright © The Nutrition Society 1983

References

REFERENCES

Cawthorne, M. A., Bunyan, J., Diplock, A. T., Murrell, E. A. & Greenm, J. (1968). British Journal of Nutrition 22, 133–140.CrossRefGoogle Scholar
Donoghue, S., Kronfeld, D. S., Berkowitz, S. J. & Copp, R. L. (1981). Journal of Nutrition 111, 365–370.CrossRefGoogle Scholar
Donoghue, S., Kronfeld, D. S. & Ramberg, C. F. (1979). Journal of Dairy Science 62, 326–332.Google Scholar
Donoghue, S., Kronfeld, D. S. & Sklan, D. (1983). British Journal of Nutrition 50, 235–248.Google Scholar
Duncan, D. B. (1955). Biometrics 11, 1–42.Google Scholar
Folch, J., Lees, M. & Stanley, G. H. S. (1957). Journal of Biological Chemistry 226, 497–509.Google Scholar
Harrison, E. H., Smith, J. E. & Goodman, D. S. (1979). Journal of Lipid Research 20, 760–771.CrossRefGoogle Scholar
Huang, H. S. & Goodman, D. S. (1965). Journal of Biological Chemistry 240, 1169–1176.Google Scholar
Hume, I. D., Mitchell, G. E. & Tucker, R. E. (1971). Journal of Nutrition 101, 1169–1176.CrossRefGoogle Scholar
Jenkins, M. Y. & Mitchell, G. V. (1975). Journal of Nutrition 105, 1600–1606.Google Scholar
Lewis, K. C., Green, M. H. & Underwood, B. A. (1981). Journal of Nutrition 111, 1135–1144.Google Scholar
Lippell, K. & Olson, J. A. (1968). Journal of Lipid Research 9, 168–175.Google Scholar
Mallia, A. K., Smith, J. E. & Goodman, D. S. (1975). Journal of Lipid Research 16, 180–188.Google Scholar
Muhilal, H. & Glover, J. (1974). British Journal of Nutrition 32, 549–558.Google Scholar
Nath, K. & Olson, J. A. (1967). Journal of Nutrition 93, 461–469.CrossRefGoogle Scholar
Neeld, J. B. & Pearson, W. N. (1963). Journal of Nutrition 79, 454–462.Google Scholar
Sklan, D., Budowski, P., Ascarelli, I. & Hurwitz, S. (1973). Journal of Nutrition 103, 1299–1305.Google Scholar
Sklan, D., Dahan, M., Budowski, P. & Hurwitz, S. (1977). Journal of Nutrition 107, 1996–2001.Google Scholar
Sklan, D. & Donoghue, S. (1982). Journal of Nutrition 112, 759–765.Google Scholar
Sklan, D., Dubrov, D., Eisner, U. & Hurwitz, S. (1975 a). Journal of Nutrition 105, 1549–1552.Google Scholar
Sklan, D., Hurwitz, S., Budowski, P. & Ascarelli, I. (1975 b). Journal of Nutrition 105, 57–63.CrossRefGoogle Scholar
Smith, J. E. & Goodman, D. S. (1979). Federation Proceedings 38, 60–65.Google Scholar
Sondergaard, E. (1972). Experientia 28, 773–774.Google Scholar
Varma, R. N. & Beaton, G. H. (1972). Canadian Journal of Physiology and Pharmacology 50, 1026–1077.Google Scholar