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What is the effect of diet and/or exercise interventions on behavioural compensation in non-exercise physical activity and related energy expenditure of free-living adults? A systematic review

  • Analiza M. Silva (a1), Pedro B. Júdice (a1), Eliana V. Carraça (a1), Neil King (a2), Pedro J. Teixeira (a1) and Luís B. Sardinha (a1)...
Abstract

Non-exercise physical activity (NEPA) and/or non-exercise activity thermogenesis (NEAT) reductions may occur from diet and/or exercise-induced negative energy balance interventions, resulting in less-than-expected weight loss. This systematic review describes the effects of prescribed diet and/or physical activity (PA)/exercise on NEPA and/or NEAT in adults. Studies were identified from PubMed, web-of-knowledge, Embase, SPORTDiscus, ERIC and PsycINFO searches up to 1 March 2017. Eligibility criteria included randomised controlled trials (RCT), randomised trials (RT) and non-randomised trials (NRT); objective measures of PA and energy expenditure; data on NEPA, NEAT and spontaneous PA; ≥10 healthy male/female aged>18 years; and ≥7 d length. The trial is registered at PROSPERO-2017-CRD42017052635. In all, thirty-six articles (RCT-10, RT-9, NRT-17) with a total of seventy intervention arms (diet, exercise, combined diet/exercise), with a total of 1561 participants, were included. Compensation was observed in twenty-six out of seventy intervention arms (fifteen studies out of thirty-six reporting declines in NEAT (eight), NEPA (four) or both (three)) representing 63, 27 and 23 % of diet-only, combined diet/exercise, and exercise-only intervention arms, respectively. Weight loss observed in participants who decreased NEAT was double the weight loss found in those who did not compensate, suggesting that the energy imbalance degree may lead to energy conservation. Although these findings do not support the hypothesis that prescribed diet and/or exercise results in decreased NEAT and NEPA in healthy adults, the underpowered trial design and the lack of state-of-the-art methods may limit these conclusions. Future studies should explore the impact of weight-loss magnitude, energetic restriction degree, exercise dose and participant characteristics on NEAT and/or NEPA.

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Corresponding author
* Corresponding author: A. M. Silva, email analiza@fmh.ulisboa.pt
References
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1. Hall, KD, Heymsfield, SB, Kemnitz, JW, et al. (2012) Energy balance and its components: implications for body weight regulation. Am J Clin Nutr 95, 989994.
2. King, NA, Caudwell, P, Hopkins, M, et al. (2007) Metabolic and behavioral compensatory responses to exercise interventions: barriers to weight loss. Obesity (Silver Spring) 15, 13731383.
3. Dulloo, AG, Jacquet, J, Montani, JP, et al. (2012) Adaptive thermogenesis in human body weight regulation: more of a concept than a measurable entity? Obes Rev 13, Suppl. 2, 105121.
4. Knuth, ND, Johannsen, DL, Tamboli, RA, et al. (2014) Metabolic adaptation following massive weight loss is related to the degree of energy imbalance and changes in circulating leptin. Obesity (Silver Spring) 22, 25632569.
5. Hall, KD, Sacks, G, Chandramohan, D, et al. (2011) Quantification of the effect of energy imbalance on bodyweight. Lancet 378, 826837.
6. Thomas, DM, Martin, CK, Heymsfield, S, et al. (2011) A simple model predicting individual weight change in humans. J Biol Dyn 5, 579599.
7. Melanson, EL, Keadle, SK, Donnelly, JE, et al. (2013) Resistance to exercise-induced weight loss: compensatory behavioral adaptations. Med Sci Sports Exerc 45, 16001609.
8. Levine, JA (2004) Nonexercise activity thermogenesis (NEAT): environment and biology. Am J Physiol Endocrinol Metab 286, E675E685.
9. Fedewa, MV, Hathaway, ED, Williams, TD, et al. (2017) Effect of exercise training on non-exercise physical activity: a systematic review and meta-analysis of randomized controlled trials. Sports Med 47, 11711182.
10. Washburn, RA, Lambourne, K, Szabo, AN, et al. (2014) Does increased prescribed exercise alter non-exercise physical activity/energy expenditure in healthy adults? A systematic review. Clin Obes 4, 120.
11. Levine, JA, Lanningham-Foster, LM, McCrady, SK, et al. (2005) Interindividual variation in posture allocation: possible role in human obesity. Science 307, 584586.
12. Heyman, MB, Young, VR, Fuss, P, et al. (1992) Underfeeding and body weight regulation in normal-weight young men. Am J Physiol 263, R250R257.
13. Velthuis-te Wierik, EJ, Westerterp, KR & van den Berg, H (1995) Impact of a moderately energy-restricted diet on energy metabolism and body composition in non-obese men. Int J Obes Relat Metab Disord 19, 318324.
14. Racette, SB, Schoeller, DA, Kushner, RF, et al. (1995) Effects of aerobic exercise and dietary carbohydrate on energy expenditure and body composition during weight reduction in obese women. Am J Clin Nutr 61, 486494.
15. Redman, LM, Heilbronn, LK, Martin, CK, et al. (2009) Metabolic and behavioral compensations in response to caloric restriction: implications for the maintenance of weight loss. PLoS ONE 4, e4377.
16. Martin, CK, Das, SK, Lindblad, L, et al. (2011) Effect of calorie restriction on the free-living physical activity levels of nonobese humans: results of three randomized trials. J Appl Physiol (1985) 110, 956963.
17. Dhurandhar, EJ, Kaiser, KA, Dawson, JA, et al. (2015) Predicting adult weight change in the real world: a systematic review and meta-analysis accounting for compensatory changes in energy intake or expenditure. Int J Obes (Lond) 39, 11811187.
18. Liberati, A, Altman, DG, Tetzlaff, J, et al. (2009) The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. PLoS Med 6, e1000100.
19. Church, TS, Martin, CK, Thompson, AM, et al. (2009) Changes in weight, waist circumference and compensatory responses with different doses of exercise among sedentary, overweight postmenopausal women. PLoS ONE 4, e4515.
20. Hollowell, RP, Willis, LH, Slentz, CA, et al. (2009) Effects of exercise training amount on physical activity energy expenditure. Med Sci Sports Exerc 41, 16401644.
21. Kozey-Keadle, S, Staudenmayer, J, Libertine, A, et al. (2014) Changes in sedentary time and physical activity in response to an exercise training and/or lifestyle intervention. J Phys Act Health 11, 13241333.
22. Martin, CK, Heilbronn, LK, de Jonge, L, et al. (2007) Effect of calorie restriction on resting metabolic rate and spontaneous physical activity. Obesity (Silver Spring) 15, 29642973.
23. Rosenkilde, M, Auerbach, P, Reichkendler, MH, et al. (2012) Body fat loss and compensatory mechanisms in response to different doses of aerobic exercise – a randomized controlled trial in overweight sedentary males. Am J Physiol Regul Integr Comp Physiol 303, R571R579.
24. Turner, JE, Markovitch, D, Betts, JA, et al. (2010) Nonprescribed physical activity energy expenditure is maintained with structured exercise and implicates a compensatory increase in energy intake. Am J Clin Nutr 92, 10091016.
25. Whybrow, S, Hughes, DA, Ritz, P, et al. (2008) The effect of an incremental increase in exercise on appetite, eating behaviour and energy balance in lean men and women feeding ad libitum. Br J Nutr 100, 11091115.
26. Willis, EA, Herrmann, SD, Honas, JJ, et al. (2014) Nonexercise energy expenditure and physical activity in the Midwest Exercise Trial 2. Med Sci Sports Exerc 46, 22862294.
27. Brehm, BJ, Spang, SE, Lattin, BL, et al. (2005) The role of energy expenditure in the differential weight loss in obese women on low-fat and low-carbohydrate diets. J Clin Endocrinol Metab 90, 14751482.
28. DeLany, JP, Kelley, DE, Hames, KC, et al. (2014) Effect of physical activity on weight loss, energy expenditure, and energy intake during diet induced weight loss. Obesity (Silver Spring) 22, 363370.
29. Kempen, KP, Saris, WH & Westerterp, KR (1995) Energy balance during an 8-wk energy-restricted diet with and without exercise in obese women. Am J Clin Nutr 62, 722729.
30. Nicklas, BJ, Gaukstern, JE, Beavers, KM, et al. (2014) Self-monitoring of spontaneous physical activity and sedentary behavior to prevent weight regain in older adults. Obesity (Silver Spring) 22, 14061412.
31. Rangan, VV, Willis, LH, Slentz, CA, et al. (2011) Effects of an 8-month exercise training program on off-exercise physical activity. Med Sci Sports Exerc 43, 17441751.
32. Schutz, Y, Nguyen, DM, Byrne, NM, et al. (2014) Effectiveness of three different walking prescription durations on total physical activity in normal- and overweight women. Obes Facts 7, 264273.
33. Wang, X, Lyles, MF, You, T, et al. (2008) Weight regain is related to decreases in physical activity during weight loss. Med Sci Sports Exerc 40, 17811788.
34. Weigle, DS (1988) Contribution of decreased body mass to diminished thermic effect of exercise in reduced-obese men. Int J Obes 12, 567578.
35. Bonomi, AG, Soenen, S, Goris, AHC, et al. (2013) Weight-loss induced changes in physical activity and activity energy expenditure in overweight and obese subjects before and after energy restriction. PLOS ONE 8, e59641.
36. Colley, RC, Hills, AP, King, NA, et al. (2010) Exercise-induced energy expenditure: implications for exercise prescription and obesity. Patient Educ Couns 79, 327332.
37. De Groot, LCPGM, Van Es, AJH, Van Raaij, JMA, et al. (1990) Energy metabolism of overweight women 1 mo and 1 y after an 8-week slimming period. Am J Clin Nutr 51, 578583.
38. Di Blasio, A, Ripari, P, Bucci, I, et al. (2012) Walking training in postmenopause: effects on both spontaneous physical activity and training-induced body adaptations. Menopause 19, 2332.
39. Goran, MI & Poehlman, ET (1992) Endurance training does not enhance total energy expenditure in healthy elderly persons. Am J Physiol 263, E950E957.
40. Herrmann, SD, Willis, EA, Honas, JJ, et al. (2015) Energy intake, nonexercise physical activity, and weight loss in responders and nonresponders: The Midwest Exercise Trial 2. Obesity (Silver Spring) 23, 15391549.
41. Hunter, GR, Byrne, NM, Sirikul, B, et al. (2008) Resistance training conserves fat-free mass and resting energy expenditure following weight loss. Obesity (Silver Spring) 16, 10451051.
42. Keytel, LR, Lambert, MI, Johnson, J, et al. (2001) Free living energy expenditure in post menopausal women before and after exercise training. Int J Sport Nutr Exerc Metab 11, 226237.
43. Leibel, RL, Rosenbaum, M & Hirsch, J (1995) Changes in energy expenditure resulting from altered body weight. N Engl J Med 332, 621628.
44. Matsuo, T, Okura, T, Nakata, Y, et al. (2007) The influence of physical activity-induced energy expenditure on the variance in body weight change among individuals during a diet intervention. Obes Res Clin Pract 1, 109117.
45. McLaughlin, R, Malkova, D & Nimmo, MA (2006) Spontaneous activity responses to exercise in males and females. Eur J Clin Nutr 60, 10551061.
46. Meijer, GA, Janssen, GM, Westerterp, KR, et al. (1991) The effect of a 5-month endurance-training programme on physical activity: evidence for a sex-difference in the metabolic response to exercise. Eur J Appl Physiol Occup Physiol 62, 1117.
47. Meijer, EP, Westerterp, KR & Verstappen, FT (1999) Effect of exercise training on total daily physical activity in elderly humans. Eur J Appl Physiol Occup Physiol 80, 1621.
48. Meijer, EP, Westerterp, KR & Verstappen, FT (2000) Effect of exercise training on physical activity and substrate utilization in the elderly. Int J Sports Med 21, 499504.
49. Van Dale, D, Schoffelen, PFM, Ten Hoor, F, et al. (1989) Effects of addition of exercise to energy restriction on 24-hour energy expenditure, sleeping metabolic rate and daily physical activity. Eur J Clin Nutr 43, 441451.
50. Van Etten, LM, Westerterp, KR, Verstappen, FT, et al. (1997) Effect of an 18-wk weight-training program on energy expenditure and physical activity. J Appl Physiol (1985) 82, 298304.
51. Weinsier, RL, Hunter, GR, Zuckerman, PA, et al. (2000) Energy expenditure and free-living physical activity in black and white women: Comparison before and after weight loss. Am J Clin Nutr 71, 11381146.
52. Armijo-Olivo, S, Stiles, CR, Hagen, NA, et al. (2012) Assessment of study quality for systematic reviews: a comparison of the Cochrane Collaboration Risk of Bias Tool and the Effective Public Health Practice Project Quality Assessment Tool: methodological research. J Eval Clin Pract 18, 1218.
53. Riou, ME, Jomphe-Tremblay, S, Lamothe, G, et al. (2015) Predictors of Energy compensation during exercise interventions: a systematic review. Nutrients 7, 36773704.
54. Westerterp, KR (2009) Assessment of physical activity: a critical appraisal. Eur J Appl Physiol 105, 823828.
55. Pontzer, H, Durazo-Arvizu, R, Dugas, LR, et al. (2016) Constrained total energy expenditure and metabolic adaptation to physical activity in adult humans. Curr Biol 26, 410417.
56. Schoeller, DA (1999) Recent advances from application of doubly labeled water to measurement of human energy expenditure. J Nutr 129, 17651768.
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