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Adherence to Practice Guidelines for Transient Ischemic Attacks in an Emergency Department

Published online by Cambridge University Press:  02 December 2014

Eddie Chang
Affiliation:
Division of Emergency Medicine, University of Alberta, Edmonton, Alberta, Canada Capital Health Authority, Edmonton, Alberta, Canada
Brian R. Holroyd
Affiliation:
Division of Emergency Medicine, University of Alberta, Edmonton, Alberta, Canada Capital Health Authority, Edmonton, Alberta, Canada
Peggy Kochanski
Affiliation:
Division of Neurology, University of Alberta, Edmonton, Alberta, Canada
Karen D. Kelly
Affiliation:
Department of Rural Health, The University of Northern Bristish Columbia, Prince George, BC Canada
Ashfaq Shuaib
Affiliation:
Capital Health Authority, Edmonton, Alberta, Canada
Brian H. Rowe
Affiliation:
Division of Emergency Medicine, University of Alberta, Edmonton, Alberta, Canada Department of Public Health Sciences, University of Alberta, Edmonton, Alberta, Canada Capital Health Authority, Edmonton, Alberta, Canada
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Abstract:

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Objective:

To evaluate the investigation and treatment of patients with a diagnosis of transient ischemic attacks (TIA) in the emergency department (ED) a tertiary care teaching hospital with a neuroscience referral program.

Methods:

A chart review was conducted in the hospital. Consecutive ED charts with a diagnosis of TIA were included; each was reviewed by independent coders using a standardized data form.

Results:

Two hundred and ninety-three TIAcharts were reviewed; the gender ratio was 1:1 with a mean age of 66 years. Most patients (75%; 95% CI: 70, 80) were evaluated by ED physicians; the remaining patients were seen directly by referral services. The median time from symptom onset to ED arrival was 2.9 hours and the duration of symptoms was 4.6 hours. Most patients received CT scans (81%; 95% CI: 73, 85), complete blood counts (74%; 95% CI: 68, 79), and electrocardiograms (75%; 95% CI: 70, 80) in the ED. In 16% (95% CI: 13, 22) a carotid doppler was performed and in 26% (95% CI: 21, 31) an outpatient doppler was booked. Among those who were discharged (75%; 95% CI: 70, 80), antithrombotic medications were not prescribed to 28% (95% CI: 22, 34).

Conclusion:

Practice variation exists with respect to the investigation and treatment of TIAs in this tertiary-care teaching hospital. Carotid doppler investigation and use of anti-platelet therapy for patients with TIAare suboptimal. Clinical practice guidelines and rapid assessment TIAclinics may change these results.

Résumé:

RÉSUMÉ:Objectif:

Évaluer l’investigation et le traitement à l’urgence des patients ayant un diagnostic d’accès ischémique cérébral transitoire (ICT).

Méthodes:

Une révision des dossiers d’un hôpital de soins tertiaires ayant un programme de référence en neurosciences a été effectuée. Chaque dossier de l’urgence comportant un diagnostic d’ICTa été révisé par des examinateurs indépendants qui attribuaient un code selon un formulaire standardisé.

Résultats:

Deux cent quatrevingt-treize dossiers de patients ayant reçu un diagnostic d’ICT ont été révisés; la proportion d’homme et de femmes était de 1:1 et l’âge moyen était de 66 ans. La plupart des patients (75%; IC 95%: 70 à 80) ont été évalués par des urgentologues; les autres patients ont été vus directement par les services de référence. L’intervalle médian du début des symptômes jusqu’à l’arrivée à l’urgence était de 2,9 heures et la durée des symptômes était de 4,6 heures. La plupart des patients ont subi une tomodensitométrie cérébrale (81%; IC 95%: 73 à 83), une formule sanguine complète (74%; IC 95%: 68 à 79), et un électrocardiogramme (75%; IC 95%: 70 à 80) à l’urgence. Chez 16% (IC 95%: 13 à 22), un Doppler carotidien a été fait et chez 26% (IC 95%: 21 à 31) un Doppler a été demandé en externe. Parmi ceux qui ont reçu leur congé de l’urgence (75%; IC 95%: 70 à 80), aucune medication antithrombotique n’a été prescrite chez 28% (IC 95%: 22 à 34).

Conclusion:

Il existe des variations quant à l’investigation et au traitement de l’ICT dans cet hôpital universitaire de soins tertiaire. L’investigation par Doppler carotidien et l’utilisation d’agents antiplaquettaires chez les patients présentant une ICT est sous-optimale. Des lignes directrices et des cliniques d’évaluation rapide de l’ICTpourraient modifier ces résultats.

Type
Research Article
Copyright
Copyright © The Canadian Journal of Neurological 2002

References

1. Goldstein, LB, Adams, R, Becker, K, et al. Primary prevention of ischemic stroke - statement for healthcare professionals from the stroke council of the American Heart Association. Circulation 2001;103:163182.CrossRefGoogle ScholarPubMed
2. Algra, A, Gijn, J. Aspirin at any dose above 30 mg offers only moderate protection after cerebral ischemia. J Neurol Neurosurg Psychiatr 1996;60:197199.Google Scholar
3. Johnston, SC, Smith, WS. Practice variability in management of transient ischemic attacks. Eur Neurol 1999;42:105108.Google Scholar
4. Barnett, HJM, Meldrum, HE, Eliasziw, M, for the North American Symptomatic Carotid Endarterectomy Trial (NASCET) Collaborators. The appropriate use of carotid endarterectomy. Can Med Assoc J 2002;166:11691175.Google ScholarPubMed
5. Gresham, GE, Phillips, TF, Wolf, PA. Epidemiological profile of long term stroke disability: the Framingham Study. Arch Phys Med Rehab 1979;60:478.Google ScholarPubMed
6. Kotila, M, Numminen, H, Waltirno, O, Kaste, M. Depression after stroke - results of the FINNSTROKE study. Stroke 1998;29:368372.CrossRefGoogle ScholarPubMed
7. Diener, HC, Cunha, L, Forbes, C, et al. European stroke prevention study 2: dipyridamole and acetylsalicylic acid in the secondary prevention of stroke. J Neurosci 1996;143:113.Google Scholar
8. Hart, RG, Benavente, O, McBride, R, Pearce, LA. Antithrombotic therapy to prevent stroke in patients with atrial fibrillation: a meta-analysis. Ann Intern Med 1999;131:492501.Google Scholar
9. Hass, WK, Easton, JD, Adams, HP Jr, et al. A randomized trial comparing ticlopidine hydrochloride with aspirin for the prevention of stroke in high-risk patients. N Engl J Med 1989;321:501507.Google Scholar
10. North American Symptomatic Carotid Endarterectory Trial Collaborators. Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade stenosis. N Engl J Med 1991;325:445458.Google Scholar
11. CAPRIE Sterring Committee. A randomized, blinded trial of clopidogrel versus aspirin in patients at risk of ischemic events. Lancet 1996;348:13291339.CrossRefGoogle Scholar
12. Dennis, M, Bamford, J, Sandercock, P, Warlow, C. Prognosis of transient ischemic attacks in the Oxfordshire community stroke project. Stroke 1990;21:848853.CrossRefGoogle ScholarPubMed
13. Bamford, J, Sandercock, P, Dennis, M, Burn, J, Warlow, C. Classification and natural history of clinically identifiable subtypes of cerebral infarction. Lancet 1991;337:1521.Google Scholar
14. Wozniak, MA, Kittner, SJ, Price, TR, et al. Stroke location is not associated with return to work after first ischemic stroke. Stroke 1999;30:25682573.Google Scholar
15. Culebras, A, Kase, CS, Masdeu, JC, et al. Practice guidelines for the use of imaging in transient ischemic attacks and acute stroke. Stroke 1997;28:14801497.Google Scholar
16. Kramer, MS, Feinstein, AR. Clinical biostatistics. LIV. The biostatistics of concordance. Clin Pharmacol Ther 1981;29:111123.CrossRefGoogle ScholarPubMed
17. Johnston, SC, Gress, DR, Browner, WS, Sidney, S. Short-term prognosis after emergency department diagnosis of TIA. JAMA 2000;284:29012906.CrossRefGoogle ScholarPubMed
18. Albers, GW, Hart, RG, Lutsep, HL, Newel, DW, Sacco, RL. Supplement to the guidelines for management of transient ischemic attack. Stroke 1999;30:25022511.Google Scholar
19. Levy, DE. How transient are transient ischemic attacks? Neurology 1988;38:674677.Google Scholar
20. Feinberg, WM, Albers, GW, Barnett, HJM, et al. Guidelines for the management of transient ischemic attacks. Circulation 1994;89:29502965.Google Scholar
21. Economic cost of cardiovascular disease. American Heart Association. 2001.Google Scholar