1.Amassian, VE, Steward, M.Quick, GJ, Rosenthal, JC.Physiological basis of motor effects of a transient stimulus to cerebral cortex. Neurosurgery 1987; 20: 74–93.
2.Day, BL, Dressier, D, Maertens, de Noordhout A, Marsden, CD, et al.Electrical and magnetic stimulation of the human motor cortex: surface EMG and single motor unit responses. J Physiol (Lond) 1989; 412: 449–473.
3.Edgley, SA, Eyre, JA, Lemon, RN, Miller, S.Excitation of the corti-cospinal tract by electromagnetic and electrical stimulation of the scalp in the macaque monkey. J Physiol (Lond) 1990; 425: 301–320.
4.Porter, R.The cortico-motoneuronal component of the pyramidal tract: corticomotoneuronal connections and functions in primates. Brain Res Rev 1985; 357: 1–26.
5.Porter, R.The corticomotoneuronal projections: synaptic events related to skilled movement. Proc Roy Soc Lond (Biol) 1987; 231: 147–168.
6.Phillips, CG, Porter, R.Corticospinal Motoneurons. Academic Press, New York, 1977.
7.Davidoff, RA. The pyramidal tract. Neurology 1990; 40: 332–339.
8.Iwatsubo, T, Kuzuhara, S, Kanemitsu, A, et al.Corticofugal projections to the motor nuclei of the brainstem and spinal cord in humans. Neurology 1990; 40: 309–312.
9.Sillevis, Smitt PAE, de, Jong JMBV. Animal models of amyotrophic lateral sclerosis and spinal muscular atrophy. J Neurol Sci 1989; 91: 231–258.
10.Eisen, A, Kim, S, Pant, B.Amyotrophic lateral sclerosis (ALS): a phylogenetic disease of the corticomotoneuron? Muscle Nerve 1992; 15: 219–228.
11.Eisen, A, Calne, DB. Amyotrophic lateral sclerosis, Parkinson's disease and Alzheimer's disease: phylogenetic disorders of the human neocortex sharing many characteristics. Can J Neurol Sci 1992; 19(Suppl): 117–120.
12.Charcot, JM. Clinical Lectures on Diseases of the Nervous System. Vol. III (translated by Savill, T), The New Sydenham Society, London, 1889: 164–182.
13.Keimahan, JA, Hudson, AJ. Changes in sizes of cortical and lower motor neurons in amyotrophic lateral sclerosis. Brain 1991; 114: 843–853.
14.Cheney, PD, Fetz, EE. Comparable patterns of muscle facilitation evoked by individual corticomotoneuronal (CM) cells and by single intracortical microstimuli in primates: evidence of functional groups of CM cells. J Neurophysiol 1985; 53: 786–804.
15.Humphrey, DR. Representation of movements and muscles within the primate precentral motor cortex: historical and current perspectives. Fed Proc 1986; 45: 2687–2699.
16.Wiesendanger, M.Output organization of the rolandic cortex as revealed by electrical stimulation. In: Rossini, PM, Marsden, CD, eds. Non-Invasive Stimulation of Brain and Spinal Cord: Fundamentals and Clinical Applications. New York: Alan R. Liss, Inc 1988; 23–35.
17.Homberg, V, Stephan, KM, Netz, J.Transcranial stimulation of motor cortex in upper motor neuron syndrome: its relation to motor deficit. Electroencephalogr Clin Neurophysiol 1991; 81: 377–388.
18.Rowland, LP. Ten central themes in a decade of ALS research. In: Rowland, LP, ed. Advances in Neurology, Vol. 56: Amyotrophic Lateral Sclerosis and Other Motor Neuron Diseases. Raven Press Ltd., 1991: 3–23.
19.Parry, GJ, Clarke, S.Multifocal acquired demyelinating neuropathy masquerading as motor neuron disease. Muscle Nerve 1988; 11: 103–107.
20.Pestronk, A.Invited review: motor neuronopathies, motor neuron disorders, and antiglycolipid antibodies. Muscle Nerve 1991; 14: 927–936.
21.Daube, JR. Electrophysiolgical studies in the diagnosis and prognosis of motor neuron diseases. Neurol Clin 1985; 3: 473–493.
22.Eisen, A, Shtybel, W.Clinical experience with transcranial magnetic stimulation. Muscle Nerve 1990; 13: 995–1011.
23.Hufnagel, A, Elger, CE, Marx, W, Ising, A.Magnetic stimulation motor-evoked potentials in epilepsy: effects of the disease and anticonvulsant medications. Ann Neurol 1990; 28: 680–686.
24.Caramia, MD, Cicinelli, P, Paradiso, C, Marioenzi, R, et al.Excitability changes of muscular responses to magnetic brain stimulation in patients with central motor disorders. Electroencephalogr Clin Neurophysiol 1991; 81: 243–250.
25.Wassermann, EM, McSahane, LM, Hallett, M, Cohen, LG. Noninvasive mapping of muscle representations in human motor cortex. Electroencephalogr Clin Neurophysiol 1992; 85: 1–8.
26.Hugon, J, Lubeau, M, Tabarard, F, Chazot, F, Vallat, JM, et al.Central motor conduction in motor neuron disease. Ann Neurol 1987; 22: 544–546.
27.Ingram, DA, Swash, M.Central motor conduction is abnormal in motor neuron disease. J Neurol Neurosurg Psychiatry 1987; 50: 159–166.
28.Schriefer, TN, Hess, CW, Mills, KR, Murray, NM. Central motor conduction studies in motor neuron disease using magnetic brain stimulation. Electroencephalogr Clin Neurophysiol 1989; 74: 431–437.
29.Eisen, A, Shytbel, W, Murphy, K, Hoirch, M.Cortical magnetic stimulation in amyotrophic lateral sclerosis. Muscle Nerve 1990; 13: 146–151.
30.Berardelli, A, Inghilleri, M, Cruccu, G, Mercuri, B, Manfredi, M.Electrical and magnetic transcranial stimulation in patients with corticospinal damage due to stroke or motor neuron disease. Electroencephalogr Clin Neurophysiol 1991; 81: 389–396.
31.Day, BL, Rothwell, JC, Thompson, PD, Dick, JP, Cowan, JMA, et al. 2. Multiple descending volleys. Brain 1987; 110: 1191–1209.
32.Muller, K, Homberg, V, Lenard, HG.Magnetic stimulation of motor cortex and nerve roots in children. Maturation of corticomotoneuronal projections. Electroencephalogr Clin Neurophysiol 1991; 81: 63–70.
33.Carpenter, S, Karpati, G, Durham, H.Dendritic attrition precedes motor neuron death in amyotrophic lateral sclerosis (ALS). Neurology 1988; 38 (Suppl): 252.
34.Hess, CW, Mills, KR, Murray, NMF. Magnetic stimulation of the human brain: facilitation of motor responses by voluntary contraction of ipsilateral and contralateral muscles with additional observations in an amputee. Neurosci Lett 1986; 71: 235–240.
35.Rothwell, JC, Thompson, PD, Day, BL, Dick, JPR, Kachi, T, et al.Motor cortical stimulation in intact man. 1. General characteristics of EMG responses in different muscles. Brain 1987; 110: 1173–1190.
36.Thompson, PD, Day, BL, Rothwell, JC, D, Dressier, Maertens, de Noordhout A, et al.Further observation on the facilitation of muscle responses to cortical stimulation by voluntary contraction. Electroencephalogr Clin Neurophysiol 1991; 81: 397–402.
37.Plaitakis, A.Glutamate dysfunction and selective motor neuron degeneration in amyotrophic lateral sclerosis: a hypothesis. Ann Neurol 1990; 28: 3–8.
38.Young, AB, Penney, JB, Dauth, GW, et al.Glutamate or aspartate as a possible neurotransmitter of cerebral corticofugal fibers in the monkey. Neurology 1983; 33: 1513–1516.
39.Shaw, PJ, Ince, PG, Johnson, M, EK, Perry, Candy, J.The quantitative autoradiographic distribution of [3H]MK-801 binding sites in normal human spinal cord. Brain Res 1991; 539: 164–168.
40.Malessa, S, Leigh, PN, Bertel, O, Sluga, E, Hornykeiwicz, O. Amyotrophic lateral sclerosis: glutamate dehydrogenase and transmitter amino acids in the spinal cord. J Neurol Neurosurg Psychiatry 1991; 54: 984–988.
41.Rothstein, JD, Martin, LJ, Kuncl, RW.Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis. N Engl J Med 1992; 326: 1464–1468.
