Gomez, CR. Time is Brain. J Stroke Cerebrovasc Dis. 1993;3(1):1-2.
Saver, JL. Time is brain—quantified. Stroke. 2006;37(1):263-266.
Hacke, W, Kaste, M, Bluhmki, E, Brozman, M, et al. Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. NEJM. 2008;359(13):1317-1329.
Bluhmki, E, Chamorro, A, Dávalos, A, et al. Stroke treatment with alteplase given 3.0–4.5 h after onset of acute ischaemic stroke (ECASS III): additional outcomes and subgroup analysis of a randomised controlled trial. Lancet Neurol. 2009;8(12):1095-1102.
Sandercock, P, Wardlaw, JM, Lindley, RI, et al. The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST-3]): a randomised controlled trial. Lancet. 2012;379(9834):2352-2363.
Alberts, MJ, Latchaw, RE, Jagoda, A, et al. Revised and updated recommendations for the establishment of primary stroke centers: A summary statement from the brain attack coalition. Stroke. 2011;42:2651-2665.
Marler, JR, Winters Jones, P, Emr, M. The National Institute of Neurological Disorders and Stroke: Proceedings of National Symposium on Rapid Identification and Treatment of Acute Stroke. Bethesda, MD: National Institute of Neurological Disorders and Stroke; 1997.
Schwamm, LH.. Primary Stroke Center Certification. Honolulu, HI: International Stroke Conference; 2013.
Casaubon, LK, Suddes, M, on behalf of the Acute Stroke Care Writing Group. Chapter 3: Hyperacute Stroke Care. In Lindsay MP, Gubitz G, Bayley M, Phillips S (Editors) on behalf of the Canadian Stroke Best Practices and Standards Advisory Committee Canadian Best Practice Recommendations for Stroke Care.
2013. Ottawa, Ontario Canada:Canadian Stroke Network and Heart and Stroke Foundation of Canada.
Parkinson, NC. Parkinson's law. Economist. 1955.
Christou, I, Alexandrov, AV, Burgin, WS, et al. Timing of recanalization after tissue plasminogen activator therapy determined by transcranial Doppler correlates with clinical recovery from ischemic stroke. Stroke. 2000;3:1812-1816.
Saver, JL, Fonarow, GC, Smith, EE, et al. Time to treatment with intravenous tissue plasminogen activator and outcome from acute ischemic stroke. JAMA. 2013;309(23):2480-2488.
Rawles, J.. Magnitude of benefit from earlier thrombolytic treatment in acute myocardial infarction: new evidence from Grampian region early anistreplase trial (GREAT). BMJ. 1996;312(7025):212-215.
Lerner, EB, Moscati, RM. The golden hour: scientific fact or medical “urban legend”?
Acad Emerg Med. 2001;8(7):758-760.
Lees, KR, Bluhmki, E, Von Kummer, R, et al. Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials. Lancet. 2010;375(9729):1695-1703.
Lindsberg, PJ, Häppölä, O, Kallela, M, Valanne, L, Kuisma, M, Kaste, M. Door to thrombolysis: ER reorganization and reduced delays to acute stroke treatment. Neurology. 2006;67(2):334-336.
Meretoja, A, Strbian, D, Mustanoja, S, Tatlisumak, T, Lindsberg, PJ, Kaste, M. Reducing in-hospital delay to 20 minutes in stroke thrombolysis. Neurology. 2012;79(4):306-313.
Meretoja, A, Weir, L, Ugalde, M, et al. Helsinki model cut stroke thrombolysis delays to 25 minutes in Melbourne in only 4 months. Neurology. 2013;81(12):1071-1076.
Fonarow, GC, Smith, EE, Saver, JL, et al. Improving door-to-needle times in acute ischemic stroke: The design and rationale for the american heart association/american stroke association's target: Stroke initiative. Stroke. 2011;42:2983-2989.
Fonarow, GC, Zhao, X, Smith, EE, et al. Door-to-needle times for tissue plasminogen activator administration and clinical outcomes in acute ischemic stroke before and after initiation of a quality improvement initiative. JAMA. 2014;311(16):1632-1640.
Fonarow, GC, Smith, EE, Saver, JL, et al. Improving door-to-needle times in acute ischemic stroke the design and rationale for the American Heart Association/American Stroke Association's target: stroke initiative. Stroke. 2011;42(10):2983-2989.
Schwamm, LH, Holloway, RG, Amarenco, P, et al. A review of the evidence for the use of telemedicine within stroke systems of care. A scientific statement from the American Heart Association/ American Stroke Association. Stroke. 2009;40:2616-2634.