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Oculodermal Melanosis (Naevus of Ota) Complicated by Multiple Intracranial Tumors

Published online by Cambridge University Press:  18 September 2015

W.J. Horsey*
Affiliation:
Departments of Neurosurgery, Department of Neuropathology and Dermatology, University of Toronto
J.M. Bilbao
Affiliation:
Departments of Neurosurgery, Department of Neuropathology and Dermatology, University of Toronto
J. Nethercott
Affiliation:
Departments of Neurosurgery, Department of Neuropathology and Dermatology, University of Toronto
R. Myers
Affiliation:
Departments of Neurosurgery, Department of Neuropathology and Dermatology, University of Toronto
H.J. Hoffman
Affiliation:
Departments of Neurosurgery, Department of Neuropathology and Dermatology, University of Toronto
*
Michael's Hospital, 30 Bond Street, Toronto, Ontario, M5B 1W8, Canada
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A thirty-seven year old, East Indian female was admitted to St. Michael's Hospital on July 26, 1979 complaining of headache, diplopia, nausea and vomiting.

In April of 1978 she was referred to a neurologist for investigation of headache. Neurological examination was normal. An X-ray of her skull revealed a lytic lesion, 2 cms. in diameter, in the right frontal area. A bone scan showed no abnormality. Further study was refused. A left facial “birth mark” was noted.

Type
University of Toronto Neurosurgical Rounds No. 2
Copyright
Copyright © Canadian Neurological Sciences Federation 1980

References

REFERENCES

Albert, E.M., Scheie, H.C. (1963). Naevus of Ota with malignant melanoma of the choroid. Arch. Ophthalmol. 69: 774777.CrossRefGoogle Scholar
Allen, A. and Spitz, S. (1953). Malignant Melanoma. Cancer, 6: 145.3.0.CO;2-C>CrossRefGoogle ScholarPubMed
Dodd, W.A. (1977). Naevus of Ota and naevus of Ito. Clinical Dermatology, Volume 2. Dennis, D.J., Dodson, R.L., and McGuire, J. (Ed.) Unit 11–45: 14. Harper & Row Publishers, Inc. Hagerstown, Maryland.Google Scholar
Dorsey, C, and Montgomery, H. (1954). Blue naevus and its distinction from Mongolian Spot and the naevus of Ota. J. Invest. Derm. 22: 225236.CrossRefGoogle Scholar
Enriquez, R., Egbert, B., Bullock, J. (1973). Primary malignant melanoma of central nervous system. Arch. Path. 95: 392395.Google ScholarPubMed
Fitzpatrick, T., and Mihm, M. (1971). Abnormalities of the melanin pigmentary system. Dermatology in General Medicine. McGraw-Hill, New York.Google Scholar
Font, R.L., Reynolds, A.M., Zimmerman, L.E. (1967). Diffuse malignant melanoma of the iris in the naevus of Ota. Arch. Ophthalmol. 77: 513518.CrossRefGoogle Scholar
Gomez-Gonzalez, J., Roselli, A., Rodriguez, A. (1965). Melanosis oculo-dermica, melanoblastosis leptomeningea and melanoma intracerebral primario. Univ. Med. 7: 4752.Google Scholar
Gottlieb, J.A., Frei, E., Luce, J.K., (1972). Evaluation of the management of patients with cerebral metastases from malignant melanoma. Cancer, 29: 701705.3.0.CO;2-S>CrossRefGoogle ScholarPubMed
Hadasa, A. (1970). Malignant melanoma in a case of bilateral naevus of Ota. Arch. Ophthalmol. 84: 176178.Google Scholar
Hagler, W.S., Brown, C.C. (1966). Malignant melanoma of the orbit arising in naevus of Ota. Trans. Am. Ac. Ophthalmol. & Otol., 70: A–17, A–22.Google Scholar
Harmer, C.L. (1976). The radiotherapy of melanoma. Clinical and Experimental Dermatology. 1, 29.CrossRefGoogle ScholarPubMed
Harwood, A.R. and Simpson, W.J. (1977). Radiation therapy of cerebral metastases: A randomized prospective clinical trial. Int. J. Radiation Oncol. Biol. Phys. 2: 10911094.CrossRefGoogle ScholarPubMed
Hidano, A., Kajima, H., Mizutani, Miyasata, H., and Niimura, M. (1967). Natural history of naevus of Ota. Arch. Derm. 95: 187195.CrossRefGoogle Scholar
Hulke, J.W. (1861). A series of cases of carcinoma of the eyeball. Ophthalmol. Hosp. Rep. 3: 279286.Google Scholar
Ito, M. (1954). Naevus fusco-caeruleus. Tohoku. J. Exp. Med. 60: 10.Google Scholar
Ito, M. and Yoshida, K. (1952). Studies on melain; VU naevus fusco-caeruleus oph-thalmo-maxillaris. Ota, Tohuko. J. Exper. Med. (Suppl. 1) 55: 3443.CrossRefGoogle Scholar
Keen, C. (1979). Personal communication.Google Scholar
Kojima, K., Natsume, C, Houda, A. et al (1959). A melanoma of the optic chiasm occurs in a case of Ota’s naevus and melanosis bulbi. Jap. J. Clin. Ophthalmol. 13: 502504.Google Scholar
Menter, M.A., Griessel, P.J.C., and Deklerk, D.J. (1971). Giant blue naevus of the scalp with underlying skull defect. Br. J. Derm., 85: 7375.CrossRefGoogle Scholar
Ota, M. (1939). Naevus fusco-caeruleus oph-thalmo-maxillaris. Jap. J. Dermatol. 46: 369.Google Scholar
Patel, J.K., Didolkar, M.S., Pickren, J.W., Moore, R.H. (1978). Metastatic pattern of malignant melanoma. Am. J. Surg. 235: 807810.CrossRefGoogle Scholar
Posner, J.B. (1977). Management of central nervous system metastases. Seminars in Oncology. 4: 8191.Google ScholarPubMed
Rodriguez, H., and Ackerman, L. (1968). Cellular blue naevus — clinico-pathological study of forty-five cases. Cancer, 21: 393405.3.0.CO;2-K>CrossRefGoogle Scholar
Sang, D.N., Albert, D.M., Sober, A.J., McMeekin, T.O. (1977). Naevus of Ota with contralateral cerebral melanoma. Arch. Ophthalmol. 95: 18201824.CrossRefGoogle ScholarPubMed
Silverberg, G., Kadin, M., Dorfman, R., Hanbery, J. and Prolo, D. (1971). Invasion of the brain by a cellular blue naevus of the scalp. A case report with light and electron microscopic studies. Cancer, 27: 349355.3.0.CO;2-R>CrossRefGoogle ScholarPubMed
Slaughter, J.C., Hartman, J.M. and Kempe, L. et al (1969). Neurocutaneous melanosis and leptomeningeal melanoma-tosis in children. Arch. Pathol. 88: 298304.Google ScholarPubMed
Speakman, J.S., Phillips, M.J. (1973). Cellular and malignant blue naevus complicating oculodermal melanosis. Can. J. Ophthalmol. 8: 539547.Google ScholarPubMed
Steinberg, J.M., Gillespie, J.J.. Mackay, B., Benjamin, R. and Leavens, R. (1978). Meningeal melan-ocytoma with invasion of the thoracic spinal cord. J. Neurosurg. 48: 818824.CrossRefGoogle ScholarPubMed
Willis, R.A. (1948). Pathology of Tumors. London, Butterworth & Co. (Publishers) Ltd. pp. 913914.Google Scholar