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Biometric and developmental gene–environment interactions: Looking back, moving forward

  • James Tabery (a1)
Abstract
Abstract

A history of research on gene–environment interaction (G × E) is provided in this article, revealing the fact that there have actually been two distinct concepts of G × E since the very origins of this research. R. A. Fisher introduced what I call the biometric concept of G × E (G × EB), whereas Lancelot Hogben introduced what I call the developmental concept of G × E (G × ED). Much of the subsequent history of research on G × E has largely consisted of the separate legacies of these separate concepts, along with the (sometimes acrimonious) disputes that have arisen time and again when employers of each have argued over the appropriate way to conceptualize the phenomenon. With this history in place, more recent attempts to distinguish between different concepts of G × E are considered, paying particular attention to the commonly made distinction between “statistical interaction” and “interactionism,” and Michael Rutter's distinction between statistical interaction and “the biological concept of interaction.” I argue that the history of the separate legacies of G × EB and G × ED better supports Rutter's analysis of the situation and that this analysis best paves the way for an integrative relationship between the various scientists investigating the place of G × E in the etiology of complex traits.

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Corresponding author
Address correspondence and reprint requests to: James Tabery, Department of Philosophy, University of Utah, Salt Lake City, UT 84112; E-mail: tabery@philosophy.utah.edu.
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G. E. Allen (1986). The Eugenics Record Office, Cold Spring Harbor, 1910–1940: An essay in institutional history. Osiris, 2, 225264.

A. Caspi , & T. E. Moffitt (2006). Gene–environment interactions in psychiatry: Joining forces with neuroscience. Nature Reviews Neuroscience, 7, 583590.

A. Caspi , J. McClay , T. E. Moffitt , J. Mill , J. Martin , I. W. Craig , (2002). Role of genotype in the cycle of violence in maltreated children. Science, 297, 851854.

R. M. Cooper , & J. P. Zubek (1958). Effects of enriched and restricted early environments on the learning ability of bright and dull rats. Canadian Journal of Psychology, 12, 159164.

M. W. Feldman , & R. C. Lewontin (1975). The heritability hang-up. Science, 190, 11631168.

J. Hagen (2003). The statistical frame of mind in systematic biology from Quantitative Zoology to Biometry. Journal of the History of Biology, 36, 353384.

D. Hamer (2002). Rethinking behavior genetics. Science, 298, 7172.

D. O. Hebb , & K. Williams (1946). A method of rating animal intelligence. Journal of General Psychology, 34, 5965.

A. R. Jensen (1969). How much can we boost IQ and scholastic achievement? Harvard Educational Review, 39, 1123..

K. S. Kendler (2005). Psychiatric genetics: A methodologic critique. American Journal of Psychiatry, 162, 311.

J. Krafka (1920). The effect of temperature upon facet number in the bar-eyed mutant of Drosophila. Journal of General Physiology, 2, 409464.

D. Layzer (1972). Science or superstition? (A physical scientist looks at the IQ controversy.) Cognition, 1, 265299.

S. Mitchell (2003). Biological complexity and integrative pluralism. Cambridge: Cambridge University Press.

J. D. Moreno (2003). Neuroethics: An agenda for neuroscience and society. Nature Reviews Neuroscience, 4, 149153.

E. Parens (2004). Genetic differences and human identities: On why talking about behavioral genetics is important and difficult. Hastings Center Report, Supplement 34, S1S36.

R. Plomin , J. C. DeFries , & J. C. Loehlin (1977). Genotype–environment interaction and correlation in the analysis of human behavior. Psychological Bulletin, 84, 309322.

R. Plomin , & S. Hershberger (1991). Genotype–environment interaction. In T. D. Wachs & R. Plomin (Eds.), Conceptualization and measurement of organism–environment interaction (pp. 2943). Washington, DC: American Psychological Association.

M. Rutter (2006). Genes and behavior: Nature–nurture interplay explained. Malden, MA: Blackwell.

M. Rutter , & A. Pickles (1991). Person–environment interactions: Concepts, mechanisms, and implications for data analysis. In R. Plomin & T. D. Wachs (Eds.), Conceptualization and measurement of organism–environment interaction (pp. 105141). Washington, DC: American Psychological Association.

S. Scarr (1995). Commentary on Gottlieb's “Some conceptual deficiencies in ‘developmental’ behavior genetics.” Human Development, 38, 154158.

K. F. Schaffner (2006). Reduction: The Cheshire cat problem and a return to roots. Synthese, 151, 377402.

N. Sesardic (2005). Making sense of heritability. Cambridge: Cambridge University Press.

M. K. Surbey (1994). Discussion: Why expect a horse to fly?, reply to Wahlsten. Canadian Psychology, 35, 261264.

J. Tabery (2004). The “evolutionary synthesis” of George Udny Yule. Journal of the History of Biology, 37, 73101.

E. A. Thompson (1990). R.A. Fisher's contributions to genetical statistics. Biometrics, 46, 905914.

G.-J. Vreeke (2000). Nature, nurture and the future of the analysis of variance. Human Development, 43, 3245.

D. Wasserman (2004). Is there value in identifying individual genetic predispositions to violence? Journal of Law, Medicine and Ethics, 32, 2433.

G. P. Wells (1978). Lancelot Thomas Hogben. Biographical Memoirs of Fellows of the Royal Society of London, 24, 183221.

F. Yates , & K. Mather (1963). Ronald Aylmer Fisher. Biographical Memoirs of Fellows of the Royal Society of London, 9, 91120.

G. U. Yule (1902). Mendel's laws and their probable relations to intra-racial heredity. The New Phytologist, 1, 193207, 222–238.

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Development and Psychopathology
  • ISSN: 0954-5794
  • EISSN: 1469-2198
  • URL: /core/journals/development-and-psychopathology
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