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Disinhibition and borderline personality disorder

Published online by Cambridge University Press:  12 December 2005

JOEL T. NIGG ,
KENNETH R. SILK ,
GILLIAN STAVRO  and
TORRI MILLER
JOEL T. NIGG
Affiliation:
Michigan State University
KENNETH R. SILK
Affiliation:
University of Michigan
GILLIAN STAVRO
Affiliation:
Michigan State University
TORRI MILLER
Affiliation:
Michigan State University
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Abstract

We review different conceptions of inhibitory control that may be relevant to the regulatory problems featured in borderline personality disorder (BPD). These conceptions have often been framed with regard to personality traits of inhibitory control, but can also be related to cognitive measures of response suppression as well as affect regulation. Reactive behavioral inhibition is relatively unstudied in relation to BPD. A substantial amount of literature links executive function problems with BPD, but that literature has not isolated executive response inhibition nor been controlled for other personality disorder symptoms of antisociality, attention-deficit/hyperactivity disorder (ADHD), or depression, anxiety, or posttraumatic symptoms. We therefore conducted a study of this question looking at BPD symptoms in an adult sample with a small number of BPD subjects and other disorders. Results indicated that symptoms of BPD were correlated with response inhibition (measured by stop signal reaction time) even after controlling for the overlap of stop inhibition with ADHD, antisociality, and other Axis II disorder symptoms. We conclude by hypothesizing discrete developmental routes to BPD, based on different mechanism breakdowns, which would be amenable to empirical investigation at the cognitive or trait level of analysis.Portions of this work were supported by National Institute of Mental Health Grant R01-MH63146 (J.N., PI).

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Type
Research Article
Information
Development and Psychopathology , Volume 17 , Issue 4 , December 2005 , pp. 1129 - 1149
Copyright
© 2005 Cambridge University Press

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References

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