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Effects of early intervention on EEG power and coherence in previously institutionalized children in Romania

  • Peter J. Marshall (a1), Bethany C. Reeb (a2), Nathan A. Fox (a2), Charles A. Nelson (a3) and Charles H. Zeanah (a4)...
Abstract
Abstract

Two groups of Romanian children were compared on spectral power and coherence in the electroencephalogram (EEG) in early childhood. One group consisted of previously institutionalized children who had been randomly assigned to a foster care intervention at a mean age of 23 months. The second group had been randomized to remain in institutional care. Because of a policy of noninterference, a number of these children also experienced placement into alternative family care environments. There were minimal group differences between the foster care and institutionalized groups in EEG power and coherence across all measured frequency bands at 42 months of age. However, age at foster care placement within the foster care group was correlated with certain measures of EEG power and coherence. Earlier age at foster care placement was associated with increased alpha power and decreased short-distance EEG coherence. Further analyses separating age at placement from duration of intervention suggest that this effect may be more robust for EEG coherence than EEG band power. Supplementary analyses examined whether the EEG measures mediated changes in intellectual abilities within the foster care children, but no clear evidence of mediation was observed.

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Address correspondence and reprint requests to: Peter J. Marshall, Department of Psychology, Temple University, 701 North 13th Street, Philadelphia, PA 19122; E-mail: pjmarsh@temple.edu.
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The work reported in this article was supported by funds from the John D. and Catherine T. MacArthur Foundation. We thank Anna Smyke and Don Guthrie for their valuable conceptual and statistical input, as well as Jennifer Windsor, Gwen Gordon, Hermi Woodward, Dana Johnson, Megan Gunnar, and Dante Cicchetti for their assistance and input during the conceptualization, preparation, and revision of this work. We also acknowledge Sebastian Koga for overseeing the project in Romania, the caregivers and children who participated in this project, the Bucharest Early Intervention Project staff for their tireless work, and our many colleagues in Romania who facilitated this work, particularly B. Simion, A. Stanescu, M. Iordachescu, and C. Tabacaru. We also acknowledge the many invaluable contributions of our Romanian partner institutions: The SERA Romania Foundation, the Institute of Maternal and Child Health, and the Bucharest Departments of Child Protection.

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This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

R. J. Barry , A. R. Clarke , & S. J. Johnstone (2003). A review of electrophysiology in attention-deficit/hyperactivity disorder: I. Qualitative and quantitative electroencephalography. Clinical Neurophysiology, 114, 171183.

R. J. Barry , A. R. Clarke , R. McCarthy , & M. Selikowitz (2005). Adjusting EEG coherence for inter-electrode distance effects: An exploration in normal children. International Journal of Psychophysiology, 55, 313321.

M. A. Bell (2001). Brain electrical activity associated with cognitive processing during a looking version of the A-Not-B task. Infancy, 2, 311330.

M. A. Bell , & N. A. Fox (1996). Crawling experience is related to changes in cortical organization during infancy: Evidence from EEG coherence. Developmental Psychobiology, 29, 551561.

M. A. Bell , & N. A. Fox (1997). Individual differences in object permanence performance at 8 months: Locomotor experience and brain electrical activity. Developmental Psychobiology, 31, 287297.

S. D. Calkins , N. A. Fox , & T. R. Marshall (1996). Behavioral and physiological antecedents of inhibited and uninhibited behavior. Child Development, 67, 523540.

R. J. Chabot , F. di Michele , & L. Prichep (2005). The role of quantitative electroencephalography in child and adolescent psychiatric disorders. Child and Adolescent Psychiatric Clinics of North America, 14, 2153, v–vi.

H. T. Chugani , M. E. Behen , O. Muzik , C. Juhasz , F. Nagy , & D. C. Chugani (2001). Local brain functional activity following early deprivation: A study of postinstitutionalized Romanian orphans. NeuroImage, 14, 12901301.

T. J. Eluvathingal , H. T. Chugani , M. E. Behen , C. Juhasz , O. Muzik , M. Maqbool , (2006). Abnormal brain connectivity in children after early severe socioemotional deprivation: A diffusion tensor imaging study. Pediatrics, 117, 20932100.

M. Essl , & P. Rappelsberger (1998). EEG coherence and reference signals: Experimental results and mathematical explanations. Medical and Biological and Engineering Computing, 36, 399406.

T. Gasser , C. Jennen-Steinmetz , L. Sroka , R. Verleger , & J. Mocks (1988). Development of the EEG of school-age children and adolescents. II. Topography. Electroencephalography and Clinical Neurophysiology, 69, 100109.

T. Harmony , E. Marosi , A. E. Diaz de Leon , J. Becker , & T. Fernandez (1990). Effect of sex, psychosocial disadvantages and biological risk factors on EEG maturation. Electroencephalography and Clinical Neurophysiology, 75, 482491.

E. R. John , H. Ahn , L. Prichep , M. Trepetin , D. Brown , & H. Kaye (1980). Developmental equations for the electroencephalogram. Science, 210, 12551258.

K. MacLean (2003). The impact of institutionalization on child development. Development and Psychopathology, 15, 853884.

E. Marosi , T. Harmony , J. Becker , A. Reyes , J. Bernal , T. Fernandez , (1995). Electroencephalographic coherences discriminate between children with different pedagogical evaluation. International Journal of Psychophysiology, 19, 2332.

P. J. Marshall , Y. Bar-Haim , & N. A. Fox (2002). Development of the EEG from 5 months to 4 years of age. Clinical Neurophysiology, 113, 11991208.

P. J. Marshall , N. A. Fox , & The BEIP Core Group. (2004). A comparison of the electroencephalogram (EEG) between institutionalized and community children in Romania. Journal of Cognitive Neuroscience, 16, 13271338 [Erratum, 19, 1173–1174].

J. Millum , & E. J. Emanuel (2007). The ethics of international research with abandoned children. Science, 318, 18741875.

P. Mundy , J. Card , & N. Fox (2000). EEG correlates of the development of infant joint attention skills. Developmental Psychobiology, 36, 325338.

P. Mundy , N. Fox , & J. Card (2003). EEG coherence, joint attention and language development in the second year. Developmental Science, 6, 4854.

C. A. Nelson , C. H. Zeanah , N. A. Fox , P. J. Marshall , A. T. Smyke , & D. Guthrie (2007). Cognitive recovery in socially deprived young children: The Bucharest Early Intervention Project. Science, 318, 19371940.

E. Niedermeyer , & F. da Silva (1993). Electroencephalography: Basic principles, clinical applications, and related fields. Baltimore, MD: Williams & Wilkins.

T. G. O'Connor (2003). Early experiences and psychological development: Conceptual questions, empirical illustrations, and implications for intervention. Development and Psychopathology, 15, 671690.

G. A. Otero , F. B. Pliego-Rivero , T. Fernandez , & J. Ricardo (2003). EEG development in children with sociocultural disadvantages: A follow-up study. Clinical Neurophysiology, 114, 19181925.

S. D. Pollak (2005). Early adversity and mechanisms of plasticity: Integrating affective neuroscience with developmental approaches to psychopathology. Development and Psychopathology, 17, 735752.

A. Raine , P. H. Venables , C. Dalais , K. Mellingen , C. Reynolds , & S. A. Mednick (2001). Early educational and health enrichment at age 3–5 years is associated with increased autonomic and central nervous system arousal and orienting at age 11 years: Evidence from the Mauritius Child Health Project. Psychophysiology, 38, 254266.

M. Rutter , J. M. Kreppner , & T. G. O'Connor (2001). Specificity and heterogeneity in children's responses to profound institutional privation. British Journal of Psychiatry, 179, 97103.

M. Rutter , T. O'Connor , & The ERA Study Team. (2004). Are there biological programming effects for psychological development? Findings from a study of Romanian adoptees. Developmental Psychology, 40, 8194.

M. Sarter , G. G. Berntson , & J. T. Cacioppo (1996). Brain imaging and cognitive neuroscience: Toward strong inference in attributing function to structure. American Psychologist, 51, 1321.

A. T. Smyke , S. F. Koga , D. E. Johnson , N. A. Fox , P. J. Marshall , C. A. Nelson , (2007). The caregiving context in institution-reared and family-reared infants and toddlers in Romania. Journal of Child Psychology and Psychiatry, 48, 210218.

R. J. Somsen , & B. van Beek (1998). Ocular artifacts in children's EEG: Selection is better than correction. Biological Psychology, 48, 281300.

R. J. Somsen , B. J. van't Klooster , M. W. van der Molen , H. M. van Leeuwen , & R. Licht (1997). Growth spurts in brain maturation during middle childhood as indexed by EEG power spectra. Biological Psychology, 44, 187209.

R. W. Thatcher (1992). Cyclic cortical reorganization during early childhood. Brain and Cognition, 20, 2450.

R. W. Thatcher , D. North , & C. Biver (2005). EEG and intelligence: relations between EEG coherence, EEG phase delay and power. Clinical Neurophysiology, 116, 21292141.

D. R. Wassenaar (2006). Commentary: Ethical considerations in international research collaborations: The Bucharest Early Intervention Project. Infant Mental Health Journal, 27, 577580.

S. Weiss , & H. M. Mueller (2003). The contribution of EEG coherence to the investigation of language. Brain and Language, 85, 325343.

J. Windsor , L. E. Glaze , S. F. Koga , & the BEIP Core Group. (2007). Language acquisition with limited input: Romanian institutions and foster care. Journal of Speech, Language, and Hearing Research, 50, 13651381.

C. H. Zeanah , S. F. Koga , B. Simion , A. Stanescu , C. Tabacaru , N. A. Fox , (2006). Ethical considerations in international research collaboration: The Bucharest Early Intervention Project. Infant Mental Health Journal, 27, 559576.

C. H. Zeanah , C. A. Nelson , N. A. Fox , A. T. Smyke , P. Marshall , S. W. Parker , (2003). Designing research to study the effects of institutionalization on brain and behavioral development: The Bucharest Early Intervention Project. Development and Psychopathology, 15, 885907.

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Development and Psychopathology
  • ISSN: 0954-5794
  • EISSN: 1469-2198
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