Skip to main content
    • Aa
    • Aa
  • Get access
    Check if you have access via personal or institutional login
  • Cited by 7
  • Cited by
    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.

    Singh, Manpreet K. and Chang, Kiki D. 2012. The Neural Effects of Psychotropic Medications in Children and Adolescents. Child and Adolescent Psychiatric Clinics of North America, Vol. 21, Issue. 4, p. 753.

    Kondo, Douglas G. Hellem, Tracy L. Sung, Young-Hoon Kim, Namkug Jeong, Eun-Kee DelMastro, Kristen K. Shi, Xianfeng and Renshaw, Perry F. 2011. Review: Magnetic Resonance Spectroscopy Studies of Pediatric Major Depressive Disorder. Depression Research and Treatment, Vol. 2011, p. 1.

    Simeonova, Diana I. Jackson, Valerie Attalla, Ashraf Karchemskiy, Asya Howe, Meghan Adleman, Nancy and Chang, Kiki 2009. Subcortical volumetric correlates of anxiety in familial pediatric bipolar disorder: A preliminary investigation. Psychiatry Research: Neuroimaging, Vol. 173, Issue. 2, p. 113.

    Youngstrom, Eric A. Freeman, Andrew J. and McKeown Jenkins, Melissa 2009. The Assessment of Children and Adolescents with Bipolar Disorder. Child and Adolescent Psychiatric Clinics of North America, Vol. 18, Issue. 2, p. 353.

    Hazell, Philip and Williams, Richard 2008. Editorial review: shifting views on juvenile bipolar disorder and pervasive developmental disorder. Current Opinion in Psychiatry, Vol. 21, Issue. 4, p. 328.

    Jarvis, Kelly DelBello, Melissa P. Mills, Neil Elman, Igor Strakowski, Stephen M. and Adler, Caleb M. 2008. Neuroanatomic Comparison of Bipolar Adolescents With and Without Cannabis Use Disorders. Journal of Child and Adolescent Psychopharmacology, Vol. 18, Issue. 6, p. 557.

    Singh, Manpreet K and Chang, Kiki D 2007. Impact of bipolar disorder on selected areas of pediatric development: a research update. Pediatric Health, Vol. 1, Issue. 2, p. 199.


Will neuroimaging ever be used to diagnose pediatric bipolar disorder?

  • DOI:
  • Published online: 01 December 2006

There is a great need for discovery of biological markers that could be used diagnostically for pediatric onset disorders, particularly those with potentially confusing phenomenology such as pediatric-onset bipolar disorder (BD). Obtaining these markers would help overcome current subjective diagnostic techniques of relying on parent and child interview and symptomatic history. Brain imaging may be the most logical choice for a diagnostic tool, and certain neurobiological abnormalities have already been found in pediatric BD. However, much work remains to be done before neuroimaging can be used reliably to diagnose this disorder, and because of the nature of BD and the limitations of imaging technology and technique, neuroimaging will likely at most be only a diagnostic aide in the near future. In this paper we discuss the characteristics of pediatric BD that complicate the use of biological markers as diagnostic tools, how neuroimaging techniques have been used to study pediatric BD so far, and the limitations and potential of such techniques for future diagnostic use.This work was supported in part by NIH Grant MH64460-01 (to K.C.).

Corresponding author
Address correspondence and reprint requests to: Kiki Chang, Division of Child and Adolescent Psychiatry, Stanford University School of Medicine, 401 Quarry Road, Stanford, CA 94305-5540; E-mail:
Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Development and Psychopathology
  • ISSN: 0954-5794
  • EISSN: 1469-2198
  • URL: /core/journals/development-and-psychopathology
Please enter your name
Please enter a valid email address
Who would you like to send this to? *