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Accepted manuscript

Boulevard of Broken Rhythms: A systematic review and meta-analysis on the relationship between sleep disturbances and suicidal behavior in bipolar disorder

Published online by Cambridge University Press:  24 October 2025

Marta Bort Open the ORCID record for Marta Bort [Opens in a new window] ,
Chiara Possidente Open the ORCID record for Chiara Possidente [Opens in a new window] ,
Vincenzo Oliva Open the ORCID record for Vincenzo Oliva [Opens in a new window] ,
Michele De Prisco Open the ORCID record for Michele De Prisco [Opens in a new window] ,
Constanza Sommerhoff Open the ORCID record for Constanza Sommerhoff [Opens in a new window] ,
Giovanna Fico Open the ORCID record for Giovanna Fico [Opens in a new window] ,
Tábatha Fernández-Plaza Open the ORCID record for Tábatha Fernández-Plaza [Opens in a new window] ,
Amadeu Obach ,
Laura Montejo Open the ORCID record for Laura Montejo [Opens in a new window]  and
Anabel Martinez-Aran Open the ORCID record for Anabel Martinez-Aran [Opens in a new window]
...Show all authors
Marta Bort
Affiliation:
Departament de Medicina, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona (UB), c. Casanova, 143, 08036 Barcelona, Spain. Bipolar and Depressive Disorders Unit, Hospital Clínic de Barcelona. c. Villarroel, 170, 08036 Barcelona, Spain. Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), c. Villarroel, 170, 08036 Barcelona, Spain. Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.
Chiara Possidente
Affiliation:
Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.
Vincenzo Oliva
Affiliation:
Departament de Medicina, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona (UB), c. Casanova, 143, 08036 Barcelona, Spain. Bipolar and Depressive Disorders Unit, Hospital Clínic de Barcelona. c. Villarroel, 170, 08036 Barcelona, Spain. Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), c. Villarroel, 170, 08036 Barcelona, Spain. Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.
Michele De Prisco
Affiliation:
Departament de Medicina, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona (UB), c. Casanova, 143, 08036 Barcelona, Spain. Bipolar and Depressive Disorders Unit, Hospital Clínic de Barcelona. c. Villarroel, 170, 08036 Barcelona, Spain. Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), c. Villarroel, 170, 08036 Barcelona, Spain. Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.
Constanza Sommerhoff
Affiliation:
Departament de Medicina, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona (UB), c. Casanova, 143, 08036 Barcelona, Spain. Bipolar and Depressive Disorders Unit, Hospital Clínic de Barcelona. c. Villarroel, 170, 08036 Barcelona, Spain. Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), c. Villarroel, 170, 08036 Barcelona, Spain. Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.
Giovanna Fico
Affiliation:
Departament de Medicina, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona (UB), c. Casanova, 143, 08036 Barcelona, Spain. Bipolar and Depressive Disorders Unit, Hospital Clínic de Barcelona. c. Villarroel, 170, 08036 Barcelona, Spain. Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), c. Villarroel, 170, 08036 Barcelona, Spain. Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.
Tábatha Fernández-Plaza
Affiliation:
Departament de Medicina, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona (UB), c. Casanova, 143, 08036 Barcelona, Spain. Bipolar and Depressive Disorders Unit, Hospital Clínic de Barcelona. c. Villarroel, 170, 08036 Barcelona, Spain. Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), c. Villarroel, 170, 08036 Barcelona, Spain. Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.
Amadeu Obach
Affiliation:
Departament de Medicina, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona (UB), c. Casanova, 143, 08036 Barcelona, Spain.
Laura Montejo
Affiliation:
Departament de Medicina, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona (UB), c. Casanova, 143, 08036 Barcelona, Spain. Bipolar and Depressive Disorders Unit, Hospital Clínic de Barcelona. c. Villarroel, 170, 08036 Barcelona, Spain. Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), c. Villarroel, 170, 08036 Barcelona, Spain. Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.
Anabel Martinez-Aran
Affiliation:
Departament de Medicina, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona (UB), c. Casanova, 143, 08036 Barcelona, Spain. Bipolar and Depressive Disorders Unit, Hospital Clínic de Barcelona. c. Villarroel, 170, 08036 Barcelona, Spain. Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), c. Villarroel, 170, 08036 Barcelona, Spain. Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.
Eduard Vieta
Affiliation:
Departament de Medicina, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona (UB), c. Casanova, 143, 08036 Barcelona, Spain. Bipolar and Depressive Disorders Unit, Hospital Clínic de Barcelona. c. Villarroel, 170, 08036 Barcelona, Spain. Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), c. Villarroel, 170, 08036 Barcelona, Spain. Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.
Andrea Murru*
Affiliation:
Departament de Medicina, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona (UB), c. Casanova, 143, 08036 Barcelona, Spain. Bipolar and Depressive Disorders Unit, Hospital Clínic de Barcelona. c. Villarroel, 170, 08036 Barcelona, Spain. Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), c. Villarroel, 170, 08036 Barcelona, Spain. Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.
*
*Corresponding author: Dr. Andrea Murru, Bipolar and Depressive Disorders Unit, Department of Psychiatry and Psychology, Institute of Neurosciences, Hospital Clínic Barcelona, Address: C. de Villarroel, 170, 08036 Barcelona, Catalonia, Spain. Email: amurru@clinic.cat

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Keywords

bipolar disordersleep disturbancessuicidal ideationsuicidal attemptsinsomnia

Information

Type
Review/Meta-analysis
Information
European Psychiatry , Accepted manuscript , pp. 1 - 34
Creative Commons
Creative Common License - CCCreative Common License - BYCreative Common License - NCCreative Common License - ND
This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is unaltered and is properly cited. The written permission of Cambridge University Press must be obtained for commercial re-use or in order to create a derivative work.
Copyright
© The Author(s), 2025. Published by Cambridge University Press on behalf of European Psychiatric Association

Footnotes

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The authors contributed equally to this work.

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