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P01-223 - A Study on the Polymorphism of DRD4exoniii48bp VNTR and Executive Function in Han Chinese children with Tourette's Syndrome
Published online by Cambridge University Press: 17 April 2020
Abstract
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Objective
The relationship of DRD4exonIII48bp VNTR and executive function were studied in 86 children with Tourette's Syndrome.
Methods
86 Han Chinese children with GTS were tested using a set of neuropsychological test(Stroop test, trail making test,modified Wisconsin Card sorting test) and compared with 51 healthy control group to understand the relationship between executive deficits and genetics.
Results
Compared with normal children, The GTS group showed impairment on almost all psychological measures. In some stroop test, combined ADHD group differed from the GTS-alone group. No evidence show significantly difference among DRD4exonIII48bp VNTR and executive function.
Conclusion
GTS patient has executive function deficits,these deficits may have nothing to do with DRD4exonIII48bp VNTR.For comorbid, there is a certain influence in the executive function.
- Type
- Child and adolescent psychiatry
- Information
- Copyright
- Copyright © European Psychiatric Association 2010
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