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Brain health INnovation Diplomacy: a model binding diverse disciplines to manage the promise and perils of technological innovation

Published online by Cambridge University Press:  13 February 2020

Kylie Ternes
School of Medicine, Baylor College of Medicine, Houston, Texas, USA
Vijeth Iyengar
U.S. Administration on Aging/Administration for Community Living, U.S. Department of Health and Human Services, Washington, DC, USA
Helen Lavretsky
Department of Psychiatry, Semel Institute for Neuroscience and Human Behavior, UCLA, Los Angeles, California, USA
Walter D. Dawson
Memory and Aging Center, School of Medicine, UCSF, San Francisco, California, USA Global Brain Health Institute, San Francisco, California, USA Trinity College Dublin, Dublin, Ireland School of Medicine, Oregon Health and Science University, Portland, Oregon, USA Institute on Aging, School of Urban and Public Affairs, Portland State University, Portland, Oregon, USA
Laura Booi
Global Brain Health Institute, San Francisco, California, USA Trinity College Dublin, Dublin, Ireland
Agustin Ibanez
Memory and Aging Center, School of Medicine, UCSF, San Francisco, California, USA Global Brain Health Institute, San Francisco, California, USA Trinity College Dublin, Dublin, Ireland Institute of Cognitive and Translational Neuroscience (INCYT), INECO Foundation, Favaloro University, Buenos Aires, Argentina National Scientific and Technical Research Council (CONICET), Buenos Aires, Argentina Center for Social and Cognitive Neuroscience (CSCN), Universidad Adolfo Ibanez, Santiago, Chile Universidad Autónoma del Caribe, Barranquilla, Colombia ARC Centre of Excellence in Cognition and its Disorders, Sydney, Australia
Ipsit Vahia
McLean Hospital, Belmont, Massachusetts, USA Harvard Medical School, Cambridge, Massachusetts, USA
Charles Reynolds III
Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Steven DeKosky
McKnight Brain Institute and Department of Neurology, College of Medicine, University of Florida, Miami, Florida, USA
Jeffrey Cummings
Department of Brain Health, School of Integrated Health Sciences, Cleveland Clinic Lou Ruvo Center for Brain Health, UNLV, Las Vegas, Nevada, USA
Bruce Miller
Memory and Aging Center, School of Medicine, UCSF, San Francisco, California, USA Global Brain Health Institute, San Francisco, California, USA Trinity College Dublin, Dublin, Ireland
Carla Perissinotto
Division of Geriatrics, School of Medicine, UCSF, San Francisco, California, USA
Jeffrey Kaye
School of Medicine, Oregon Health and Science University, Portland, Oregon, USA
Harris A. Eyre*
Innovation Institute, Texas Medical Center, Houston, Texas, USA Department of Psychiatry, University of Melbourne, Melbourne, Victoria, Australia IMPACT SRC, School of Medicine, Deakin University, Geelong, Victoria, Australia Brainstorm Laboratory for Mental Health Innovation, Department of Psychiatry, Stanford University School of Medicine, Palo Alto, California, USA Discipline of Psychiatry, School of Medicine, The University of Adelaide, Adelaide, South Australia, Australia
Correspondence should be addressed to: Dr Harris Eyre, MBBS, PhD, Innovation Institute, Texas Medical Center, Suite X, 2450 Holcombe Blvd, Houston, Texas, 77006, USA. Email:



Brain health diplomacy aims to influence the global policy environment for brain health (i.e. dementia, depression, and other mind/brain disorders) and bridges the disciplines of global brain health, international affairs, management, law, and economics. Determinants of brain health include educational attainment, diet, access to health care, physical activity, social support, and environmental exposures, as well as chronic brain disorders and treatment. Global challenges associated with these determinants include large-scale conflicts and consequent mass migration, chemical contaminants, air quality, socioeconomic status, climate change, and global population aging. Given the rapidly advancing technological innovations impacting brain health, it is paramount to optimize the benefits and mitigate the drawbacks of such technologies.


We propose a working model of Brain health INnovation Diplomacy (BIND).


We prepared a selective review using literature searches of studies pertaining to brain health technological innovation and diplomacy.


BIND aims to improve global brain health outcomes by leveraging technological innovation, entrepreneurship, and innovation diplomacy. It acknowledges the key role that technology, entrepreneurship, and digitization play and will increasingly play in the future of brain health for individuals and societies alike. It strengthens the positive role of novel solutions, recognizes and works to manage both real and potential risks of digital platforms. It is recognition of the political, ethical, cultural, and economic influences that brain health technological innovation and entrepreneurship can have.


By creating a framework for BIND, we can use this to ensure a systematic model for the use of technology to optimize brain health.

Review Article
© International Psychogeriatric Association 2020

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The views expressed in this paper are those of the authors and not necessarily of the authors’ organizations including the U.S. Administration on Aging/Administration for Community Living, U.S. Department of Health and Human Services.


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