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Language impairment in euthymic, elderly patients with bipolar disorder but no dementia

  • Marcia Radanovic (a1), Paula Villela Nunes (a1), Wagner Farid Gattaz (a1) and Orestes Vicente Forlenza (a1)
  • DOI: http://dx.doi.org/10.1017/S1041610208007084
  • Published online: 01 August 2008
Abstract
ABSTRACT

Background: Neurocognitive impairment is known to occur in euthymic bipolar patients, but language alterations have not been thoroughly investigated. The aim of this study is to examine the performance in language tests of a sample of elderly patients with bipolar disorder.

Methods: We studied 33 euthymic elderly patients with bipolar disorder but no dementia and 33 healthy individuals, matched for age and education, who were compared in terms of their CAMCOG global score and its subitems.

Results: The scores obtained in language-related abilities for patients and controls, respectively, were: language (total): 27.3 (1) and 28.5 (1), p < 0.0001; comprehension: 8.6 (0.5) and 8.9 (0.3), p = 0.006; production: 18.7 (1) and 19.6 (0.9), p = <0.0001; abstraction: 6.8 (1.1) and 7.3 (0.7), p = 0.016; verbal fluency: 16.3 (4.3) and 19.6 (4.1), p = 0.003.

Conclusion: A mild but significant impairment in language-related ability scores was detected when comparing patients and controls.

Copyright
Corresponding author
Correspondence should be addressed to: Marcia Radanovic, Rua Cristiano Viana, 163 ap. 92, São Paulo – SP –Brazil05411-000. Phone: +55 11 30889708; Fax: +55 11 30889708. Email: marciaradanovic@yahoo.com.br; radano@tecway.com.br.
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International Psychogeriatrics
  • ISSN: 1041-6102
  • EISSN: 1741-203X
  • URL: /core/journals/international-psychogeriatrics
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