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Exploration of interactions of ‘blood-nano interface’ of carbon-based nanomaterials for biomedical applications

Published online by Cambridge University Press:  31 May 2019

Vishal Singh ,
Aparajita Basu ,
P.M. Shivapriya ,
Pritish Kumar Varadwaj ,
Sintu Kumar Samanta  and
Amaresh Kumar Sahoo Open the ORCID record for Amaresh Kumar Sahoo [Opens in a new window]
Vishal Singh
Affiliation:
Department of Applied Sciences, Indian Institute of Information Technology Allahabad, Allahabad, Uttar Pradesh 211012, India
Aparajita Basu
Affiliation:
Department of Applied Sciences, Indian Institute of Information Technology Allahabad, Allahabad, Uttar Pradesh 211012, India
P.M. Shivapriya
Affiliation:
Department of Applied Sciences, Indian Institute of Information Technology Allahabad, Allahabad, Uttar Pradesh 211012, India
Pritish Kumar Varadwaj
Affiliation:
Department of Applied Sciences, Indian Institute of Information Technology Allahabad, Allahabad, Uttar Pradesh 211012, India
Sintu Kumar Samanta*
Affiliation:
Department of Applied Sciences, Indian Institute of Information Technology Allahabad, Allahabad, Uttar Pradesh 211012, India
Amaresh Kumar Sahoo*
Affiliation:
Department of Applied Sciences, Indian Institute of Information Technology Allahabad, Allahabad, Uttar Pradesh 211012, India
*
a)Address all correspondence to these authors. e-mail: samantasintu@iiita.ac.in
b)e-mail: asahoo@iiita.ac.in
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Abstract

One of the most promising nanoscale materials which fascinated researchers for the last few decades owing to its unique optoelectronics and physicochemical properties are carbon-based nanomaterials (CBNs). Various forms of CBNs have been developed such as single and multi-walled carbon nanotubes, graphene, fullerenes, nanodiamonds, and fluorescent carbon quantum dots (C-Dots) whereas each form is having its own exceptional properties owing to its dimensionalities and architectures. The advent of these unique classes of nanoscale materials opens up a spectrum of new opportunities and possibilities in employing these in emerging areas of biomedical. However, successful biomedical applications greatly rely on the likelihood of the comprehensive understanding of physicochemical interactions and biological responses of CBNs. Herein, we have tried to explore the ‘blood-CBNs’ interface by including the findings of recent studies. The role of surface modifications and functionalization in order to mitigate the adverse outcomes has also been incorporated.

Keywords

nanostructurebiomedicalnanoscale
Type
REVIEW
Information
Journal of Materials Research , Volume 34 , Issue 11: Focus Issue: (Nano)materials for Biomedical Applications , 14 June 2019 , pp. 1950 - 1964
Copyright
Copyright © Materials Research Society 2019 

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Footnotes

c)

These authors contributed equally to this work.

This section of Journal of Materials Research is reserved for papers that are reviews of literature in a given area.

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