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Luminogen-functionalized mesoporous SBA-15 for fluorescent detection of antibiotic cefalexin

  • Lei Liu (a1), Xinyu Fu (a1), Hongliang Zhang (a1), Weiqing Ma (a1), Lili Zhang (a1), Yixin Zhang (a1), Meng Liu (a1), Kehan Liang (a1), Senlin Hou (a2) and Aibing Chen (a1)...

A novel luminogen-functionalized SBA-15, denoted as SNT, was developed by incorporating tris(4-bromophenyl)amine (TBPA) into SBA-15 via a “fixation-induced emission” strategy. The emission of TBPA on the matrix of SBA-15 was greatly enhanced, making the SNT possible as a fluorescence sensor. Cefalexin, a typical antibiotic, was chosen as the model analyte to be assayed and sensitive detection performance was achieved. This is the first time for cefalexin to be detected by a fluorescent method. Moreover, the SNT can be recycled by simply washing with proper solvents then used for next detection. This work provides a strategy to greatly improve the emission characteristics of fluorophores, even if a mediocre small fluorophore. It can be extended to design practical fluorescent sensors with high performance and recyclability by this strategy.

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Journal of Materials Research
  • ISSN: 0884-2914
  • EISSN: 2044-5326
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