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Body side of motor symptom onset in Parkinson's disease is associated with memory performance

Published online by Cambridge University Press:  08 September 2006

M.M. AMICK ,
J. GRACE  and
K.L. CHOU
M.M. AMICK
Affiliation:
Department of Medical Rehabilitation, Memorial Hospital of Rhode Island, Pawtucket, Rhode Island Department of Psychiatry and Human Behavior, Brown Medical School, Providence, Rhode Island
J. GRACE
Affiliation:
Department of Medical Rehabilitation, Memorial Hospital of Rhode Island, Pawtucket, Rhode Island Department of Psychiatry and Human Behavior, Brown Medical School, Providence, Rhode Island
K.L. CHOU
Affiliation:
Department of Clinical Neurosciences, Brown Medical School, Providence, Rhode Island NeuroHealth, Warwick, Rhode Island
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Abstract

The relation of body side of motor symptom onset in Parkinson's disease (PD) to memory measures associated with hemispheric dominance was examined. Fourteen patients with right body side motor symptom onset (RPD, inferred left hemisphere dysfunction) and 16 patients with left side onset (LPD, right hemisphere dysfunction) were administered measures of verbal (Hopkins Verbal Learning Test-Revised) and visual memory (Brief Visual Memory Test-Revised), that require similar task demands and are associated with left or right hemisphere dominance, respectively. The LPD group demonstrated poorer visual than verbal memory, both within group and in comparison to the RPD group. By contrast, the RPD group showed poorer verbal than visual memory within group. These findings suggest that side of motor symptom onset is associated with asymmetrical memory dysfunction (JINS, 2006, 12, 736–740.)

Keywords

LateralityDopamineLearningNeuropsychologyMovement disordersBasal ganglia
Type
BRIEF COMMUNICATIONS
Information
Journal of the International Neuropsychological Society , Volume 12 , Issue 5 , September 2006 , pp. 736 - 740
Copyright
© 2006 The International Neuropsychological Society

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