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The Cognition Battery of the NIH Toolbox for Assessment of Neurological and Behavioral Function: Validation in an Adult Sample

  • Sandra Weintraub (a1), Sureyya S. Dikmen (a2), Robert K. Heaton (a3), David S. Tulsky (a4) (a5), Philip David Zelazo (a6), Jerry Slotkin (a7), Noelle E. Carlozzi (a8), Patricia J. Bauer (a9), Kathleen Wallner-Allen (a10), Nathan Fox (a11), Richard Havlik (a10), Jennifer L. Beaumont (a7), Dan Mungas (a12), Jennifer J. Manly (a13), Claudia Moy (a14), Kevin Conway (a15), Emmeline Edwards (a16), Cindy J. Nowinski (a7) and Richard Gershon (a7)...


This study introduces a special series on validity studies of the Cognition Battery (CB) from the U.S. National Institutes of Health Toolbox for the Assessment of Neurological and Behavioral Function (NIHTB) (Gershon, Wagster et al., 2013) in an adult sample. This first study in the series describes the sample, each of the seven instruments in the NIHTB-CB briefly, and the general approach to data analysis. Data are provided on test–retest reliability and practice effects, and raw scores (mean, standard deviation, range) are presented for each instrument and the gold standard instruments used to measure construct validity. Accompanying papers provide details on each instrument, including information about instrument development, psychometric properties, age and education effects on performance, and convergent and discriminant construct validity. One study in the series is devoted to a factor analysis of the NIHTB-CB in adults and another describes the psychometric properties of three composite scores derived from the individual measures representing fluid and crystallized abilities and their combination. The NIHTB-CB is designed to provide a brief, comprehensive, common set of measures to allow comparisons among disparate studies and to improve scientific communication. (JINS, 2014, 20, 1–12)


Corresponding author

Correspondence and reprint requests to: Cognitive Neurology and Alzheimer's Disease Center Northwestern Feinberg School of Medicine 320 E. Superior, Searle 11-467 Chicago, IL 60610E-mail:


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