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  • Journal of the International Neuropsychological Society, Volume 17, Issue 2
  • January 2011, pp. 364-368

Cognitive and Functional Outcome After Out of Hospital Cardiac Arrest

  • Michael P. Alexander (a1) (a2), Ginette Lafleche (a3), David Schnyer (a4), Chun Lim (a1) and Mieke Verfaellie (a3)
  • DOI: http://dx.doi.org/10.1017/S1355617710001633
  • Published online: 04 January 2011
Abstract
Abstract

The nature of residual cognitive deficits after out of hospital cardiac arrest (OHCA) is incompletely described and has never been defined against a cardiac control (CC) group. The objective of this study is to examine neuropsychological outcomes 3 months after OHCA in patients in a “middle range” of acute severity. Thirty prospective OHCA admissions with coma >1 day and responsive but confused at 1 week, and 30 non-OHCA coronary care admissions were administered standard tests in five cognitive domains. OHCA subjects fell into two deficit profiles. One group (N = 20) had mild memory deficits and borderline psychomotor deficits compared to the CC group; 40% had returned to work. The other group (N = 10) had severe impairments in all domains. Coma duration was associated with group. Neither group had a high prevalence of depression. For most patients within the “middle range” of acute severity of OHCA, cognitive and functional outcomes at 3 months were encouraging. (JINS, 2011, 17, 364–368)

Copyright
Corresponding author
Correspondence and reprint requests to: Michael P. Alexander, MD, Cognitive Neurology Unit, KS 253, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215. E-mail: malexand@bidmc.harvard.edu
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Journal of the International Neuropsychological Society
  • ISSN: 1355-6177
  • EISSN: 1469-7661
  • URL: /core/journals/journal-of-the-international-neuropsychological-society
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