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Cognitive flexibility in anorexia nervosa and bulimia nervosa

  • KATE TCHANTURIA (a1), MARIJA BRECELJ ANDERLUH (a1), ROBIN G. MORRIS (a2), SOPHIA RABE-HESKETH (a3), DAVID A. COLLIER (a4), PATRICIA SANCHEZ (a1) and JANET L. TREASURE (a1)...
Abstract

The aim of this study was to determine if there are differences in cognitive flexibility in anorexia nervosa and bulimia nervosa. Fifty-three patients with an eating disorder (34 with anorexia nervosa and 19 with bulimia nervosa) and 35 healthy controls participated in the study. A battery of neuropsychological tests for cognitive flexibility was used, including Trail Making B, the Brixton Test, Verbal Fluency, the Haptic Illusion Test, a cognitive shifting task (CatBat) and a picture set test. Using exploratory factor analysis, four factors were obtained: 1: Simple Alternation; 2: Mental Flexibility; 3: Perseveration; and 4: Perceptual Shift. Patients with anorexia nervosa had abnormal scores on Factors 1 and 4. Patients with bulimia nervosa showed a different pattern, with significant impairments in Factors 2 and 4. These findings suggest that differential neuropsychological disturbance in the domain of mental flexibility/rigidity may underlie the spectrum of eating disorders. (JINS, 2004, 10, 513–520.)

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Corresponding author
Reprint requests to: Kate Tchanturia, P059 Eating Disorders Research Unit, Institute of Psychiatry, King's College, University of London, De Crespigny Park, London, SE5 8AF, UK. E-mail: spjeket@iop.kcl.ac.uk
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Journal of the International Neuropsychological Society
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