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Hot and Cool Executive Functions in Children with Attention-Deficit/Hyperactivity Disorder and Comorbid Oppositional Defiant Disorder

  • Tanya N. Antonini (a1), Stephen P. Becker (a1), Leanne Tamm (a1) and Jeffery N. Epstein (a1)
Abstract

While neuropsychological deficits in both “hot” and “cool” executive functions (EFs) have been documented among individuals with attention-deficit/hyperactivity disorder (ADHD), these EF deficits are not universal across all individuals with this diagnosis. One potential moderator of executive dysfunction may be the presence of comorbid oppositional defiant disorder (ODD). This study examined the association between “hot” and “cool” EFs and comorbid ODD in children with ADHD. Thirty-three children with ADHD and comorbid ODD (ADHD+ODD), 67 with ADHD without ODD (ADHD-ODD), and 30 typically developing controls participated. Children were 7–12 years of age. “Cool” EFs were assessed with a spatial span task and a card sorting test. “Hot” EFs were assessed using a delay discounting task and a gambling task. ADHD-ODD and ADHD+ODD groups performed more poorly on “cool” EF tasks than controls, but did not differ from each other. Furthermore, the number of ADHD symptoms, but not ODD symptoms, was associated with “cool” EF scores. The three groups did not differ on “hot” EF tasks and the number of ADHD or ODD symptoms was unrelated to “hot” EF scores. In sum, children with ADHD presented with “cool” EF deficits which appear to be unrelated to ODD comorbidity. However, “hot” EF deficits were not present among children with ADHD, irrespective of comorbid ODD status. (JINS, 2015, 21, 584–595)

Copyright
Corresponding author
Correspondence and reprint requests to: Jeffery Epstein, Behavioral Medicine and Clinical Psychology, Cincinnati Children’s Hospital Medical Center, 3333 Burnet Avenue, MLC 10006, Cincinnati, OH 45229-3039. E-mail: jeff.epstein@cchmc.org
References
Hide All
American Psychiatric Association (2013). Diagnostic and statistical manual of mental disorders (5th ed.) Washington, DC: Author.
American Academy of Pediatrics (2011). ADHD: Clinical practice guideline for the diagnosis, evaluation, and treatment of attention-deficit/hyperactivity disorder in children and adolescents. Pediatrics. peds-2011.
Angold, A., Costello, E.J., & Erkanli, A. (1999). Comorbidity. Journal of Child Psychology and Psychiatry, 40, 5787.
Arcos-Burgos, M., Castellanos, F.X., Pineda, D., Lopera, F., David Palacio, J., Guillermo Palacio, L., & Muenke, M. (2004). Attention-deficit/hyperactivity disorder in a population isolate: Linkage to loci at 4q13. 2, 5q33. 3, 11q22, and 17p11. The American Journal of Human Genetics, 75(6), 9981014.
Barkley, R.A. (1997). Behavioral inhibition, sustained attention, and executive functions: Constructing a unifying theory of ADHD. Psychological Bulletin, 121(1), 6594.
Barkley, R.A. (2010). Differential diagnosis of adults with ADHD: The role of executive function and self-regulation. The Journal of Clinical Psychiatry, 71(7), e17e17.
Barkley, R.A., & Fischer, M. (2010). The unique contribution of emotional impulsiveness to impairment in major life activities in hyperactive children as adults. Journal of the American Academy of Child & Adolescent Psychiatry, 49(5), 503513.
Barkley, R.A., Fischer, M., Edelbrock, C., & Smallish, L. (1991). The adolescent outcome of hyperactive children diagnosed by research criteria—III. Mother–child interactions, family conflicts and maternal psychopathology. Journal of Child Psychology and Psychiatry, 32(2), 233255.
Barkley, R.A., Edwards, G., Laneri, M., Fletcher, K., & Metevia, L. (2001). Executive functioning, temporal discounting, and sense of time in adolescents with attention deficit hyperactivity disorder (ADHD) and oppositional defiant disorder (ODD). Journal of Abnormal Child Psychology, 29(6), 541556.
Becker, S.P., Luebbe, A.M., & Langberg, J.M. (2012). Co-occurring mental health problems and peer functioning among youth with Attention-Deficit/Hyperactivity Disorder: A review and recommendations for future research. Clinical Child and Family Psychology Review, 15, 279302.
Bobadilla, L., Wampler, M., & Taylor, J. (2012). Proactive and reactive aggression are associated with different physiological and personality profiles. Journal of Social and Clinical Psychology, 31, 458487. doi:10.1521/jscp.2012.31.5.458.
Bull, R., & Scerif, G. (2001). Executive functioning as a predictor of children’s mathematics ability: Inhibition, switching, and working memory. Developmental Neuropsychology, 19(3), 273293.
Casey, B.J., Castellanos, F.X., Giedd, J.N., Marsh, W.L., Hamburger, S.D., Schubert, A.B., & Rapoport, J.L. (1997). Implication of right frontostriatal circuitry in response inhibition and attention-deficit/hyperactivity disorder. Journal of the American Academy of Child & Adolescent Psychiatry, 36(3), 374383.
Castellanos, F.X., Sonuga-Barke, E.J., Milham, M.P., & Tannock, R. (2006). Characterizing cognition in ADHD: Beyond executive dysfunction. Trends in Cognitive Sciences, 10(3), 117123.
Crosbie, J., & Schachar, R. (2001). Deficient inhibition as a marker for familial ADHD. American Journal of Psychiatry, 158(11), 18841890.
Demurie, E., Roeyers, H., Baeyens, D., & Sonuga-Barke, E. (2012). Temporal discounting of monetary rewards in children and adolescents with ADHD and autism spectrum disorders. Developmental Science, 15(6), 791800. doi:10.1111/j.1467-7687.2012.01178.x.
Dennis, M., Francis, D.J., Cirino, P.T., Schachar, R., & Fletcher, J.M. (2009). Why IQ is not a covariate in cognitive studies of neurodevelopmental disorders. Journal of the International Neuropsychological Society, 15(3), 331343.
Doyle, A.E., Faraone, S.V., Seidman, L.J., Willcutt, E.G., Nigg, J.T., Waldman, I.D., & Biederman, J. (2005). Are endophenotypes based on measures of executive functions useful for molecular genetic studies of ADHD? Journal of Child Psychology and Psychiatry, 46(7), 774803.
Factor, P.I., Rosen, P.J., & Reyes, R.A. (2013). The relation of poor emotional awareness and externalizing behavior among children with ADHD. Journal of Attention Disorders, [Epub ahead of print].
Faraone, S.V., Biederman, J., Weber, W., & Russell, R.L. (1998). Psychiatric, neuropsychological, and psychosocial features of DSM-IV subtypes of attention-deficit/hyperactivity disorder: Results from a clinically referred sample. Journal of the American Academy of Child and Adolescent Psychiatry, 37, 185193.
Fisher, S.E., Francks, C., McCracken, J.T., McGough, J.J., Marlow, A.J., MacPhie, I.L., & Smalley, S.L. (2002). A genomewide scan for loci involved in attention-deficit/hyperactivity disorder. American Journal of Medical Genetics, 70, 11831196.
Garon, N., Moore, C., & Waschbusch, D.A. (2006). Decision making in children with ADHD only, ADHD-anxious/depressed, and control children using a child version of the Iowa gambling task. Journal of Attention Disorders, 9(4), 607619.
Gau, S.S., & Shang, C.Y. (2010). Executive functions as endophenotypes in ADHD: Evidence from the Cambridge Neuropsychological Test Battery (CANTAB). Journal of Child Psychology and Psychiatry, 51(7), 838849.
Geurts, H.M., Van der Oord, S., & Crone, E.A. (2006). Hot and cool aspects of cognitive control in children with ADHD: decision-making and inhibition. Journal of Abnormal Child Psychology, 34(6), 811822.
Geurts, H.M., Verté, S., Oosterlaan, J., Roeyers, H., & Sergeant, J.A. (2005). ADHD subtypes: Do they differ in their executive functioning profile? Archives of Clinical Neuropsychology, 20, 457477.
Grant, D.A., & Berg, E. (1948). A behavioral analysis of degree of reinforcement and ease of shifting to new responses to Weigl-type card-sorting problem. Journal of Experimental Psychology, 38, 404411.
Hale, J.B., Reddy, L.A., Semrud-Clikeman, M., Hain, L.A., Whitaker, J., Morley, J., & Jones, N. (2011). Executive impairment determines ADHD medication response: Implications for academic achievement. Journal of Learning Disabilities, 44(2), 196212.
Heaton, R.K. (2003). WCST-64™: Computer version 2 research edition. Lutz, FL: Psychological Assessment Resources.
Hobson, C.W., Scott, S., & Rubia, K. (2011). Investigation of cool and hot executive function in ODD/CD independently of ADHD. Journal of Child Psychology and Psychiatry, 52(10), 10351043.
Hongwanishkul, D., Happaney, K.R., Lee, W.S., & Zelazo, P.D. (2005). Assessment of hot and cool executive function in young children: Age-related changes and individual differences. Developmental Neuropsychology, 28(2), 617644.
Humphreys, K.L., & Lee, S.S. (2011). Risk taking and sensitivity to punishment in children with ADHD, ODD, ADHD+ODD, and controls. Journal of Psychopathology and Behavioral Assessment, 33(3), 299307.
Johnson, M.W., & Bickel, W.K. (2008). An algorithm for identifying nonsystematic delay-discounting data. Experimental and Clinical Psychopharmacology, 16(3), 264.
Kalff, A.C., Hendriksen, J.G., Kroes, M., Vles, J.S., Steyaert, J., Feron, F.J., & Jolles, J. (2002). Neurocognitive performance of 5-and 6-year-old children who met criteria for attention deficit/hyperactivity disorder at 18 months follow-up: Results from a prospective population study. Journal of Abnormal Child Psychology, 30(6), 589598.
Kaufman, J., Birmaher, B., Brent, D., Rao, U., & Ryan, N. (1996). Kiddie schedule for affective disorders and schizophrenia – Present and lifetime version (K-SADS-PL).
Kaufman, A., & Kaufman, N. (2004). Kaufman Brief Intelligence Test-2. Circle Pines, MN: AGS.
Kessels, R.P., Van Zandvoort, M.J., Postma, A., Kappelle, L.J., & De Haan, E.H. (2000). The Corsi block-tapping task: standardization and normative data. Applied Neuropsychology, 7(4), 252258.
Klorman, R., Hazel-Fernandez, L.A., Shaywitz, S.E., Fletcher, J.M., Marchione, K.E., Holahan, J.M., & Shaywitz, B.A. (1999). Executive functioning deficits in attention‐deficit/hyperactivity disorder are independent of oppositional defiant or reading disorder. Journal of the American Academy of Child & Adolescent Psychiatry, 38(9), 11481155.
Kopecky, H., Chang, H.T., Klorman, R., Thatcher, J.E., & Borgstedt, A.D. (2005). Performance and private speech of children with attention-deficit/hyperactivity disorder while taking the tower of hanoi test: Effects of depth of search, diagnostic subtype, and methylphenidate. Journal of Abnormal Child Psychology, 33(5), 625638.
Krain, A.L., Wilson, A.M., Arbuckle, R., Castellanos, F.X., & Milham, M.P. (2006). Distinct neural mechanisms of risk and ambiguity: a meta-analysis of decision-making. Neuroimage, 32(1), 477484.
Luman, M., Sergeant, J.A., Knol, D.L., & Oosterlaan, J. (2010). Impaired decision making in oppositional defiant disorder related to altered psychophysiological responses to reinforcement. Biological Psychiatry, 68(4), 337344.
Martinussen, R., Hayden, J., Hogg-Johnson, S., & Tannock, R. (2005). A meta-analysis of working memory impairments in children with attention-deficit/hyperactivity disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 44(4), 377384.
Matthys, W., Van Goozen, S.H., Snoek, H., & Van Engeland, H. (2004). Response perseveration and sensitivity to reward and punishment in boys with oppositional defiant disorder. European Child & Adolescent Psychiatry, 13(6), 362364.
Miller, E.K., & Cohen, J.D. (2001). An integrative theory of prefrontal cortex function. Annual Reviews of Neuroscience, 24, 167202.
Mitchell, S.H. (1999). Measures of impulsivity in cigarette smokers and non-smokers. Psychopharmacology, 146, 455464.
Moffitt, T.E. (1990). Juvenile delinquency and attention deficit disorder: Boys’ developmental trajectories from age 3 to age 15. Child Development, 61(3), 893910.
The MTA Cooperative Group. (1999). A 14-month randomized clinical trial of treatment strategies for attention-deficit/hyperactivity disorder. Archives of General Psychiatry, 56(12), 10731086. doi:10.1001/archpsyc.56.12.1073.
Miyake, A., Friedman, N.P., Emerson, M.J., Witzki, A.H., Howerter, A., & Wager, T.D. (2000). The unity and diversity of executive functions and their contributions to complex “frontal lobe” tasks: A latent variable analysis. Cognitive Psychology, 41(1), 49100.
Mullane, J.C., & Corkum, P.V. (2007). The relationship between working memory, inhibition, and performance on the Wisconsin Card Sorting Test in children with and without ADHD. Journal of Psychoeducational Assessment, 25, 211221.
Nigg, J.T., Blaskey, L.G., Huang-Pollock, C.L., & Rappley, M.D. (2002). Neuropsychological executive functions and DSM-IV ADHD subtypes. Journal of the American Academy of Child and Adolescent Psychiatry, 41(1), 5966.
Oosterlaan, J., Scheres, A., & Sergeant, J.A. (2005). Which executive functioning deficits are associated with AD/HD, ODD/CD and comorbid AD/HD+ ODD/CD? Journal of Abnormal Child Psychology, 33(1), 6985.
Phan, K.L., Wagner, T.D., Taylor, S.F., & Liberzon, I. (2004). Functioning neuroimaging studies of human emotions. CNS Spectrums, 9(4), 258266.
Piper, B.J., Li, V., Eiwaz, M.A., Kobel, Y.V., Benice, T.S., Chu, A.M., & Mueller, S.T. (2012). Executive function on the psychology experiment building language tests. Behavior Research Methods, 44(1), 110123.
Prencipe, A., Kesek, A., Cohen, J., Lamm, C., Lewis, M.D., & Zelazo, P.D. (2011). Development of hot and cool executive function during the transition to adolescence. Journal of Experimental Child Psychology, 108(3), 621637.
Qian, Y., Shuai, L., Cao, Q., Chan, R.C., & Wang, Y. (2010). Do executive function deficits differentiate between children with attention deficit hyperactivity disorder (ADHD) and ADHD comorbid with oppositional defiant disorder? A cross-cultural study using performance-based tests and the behavior rating inventory of executive function. Clinical Neuropsychology, 24(5), 793810.
Romine, C.B., Lee, D., Wolfe, M.E., Homack, S., George, C., & Riccio, C.A. (2004). Wisconsin card sorting test with children: A meta-analytic study of sensitivity and specificity. Archives of Clinical Neuropsychology, 19(8), 10271041.
Rubia, K. (2011). “Cool” inferior frontostriatal dysfunction in Attention-Deficit/Hyperactivity Disorder versus “hot” ventromedial orbitofrontal-limbic dysfunction in conduct disorder: A review. Biological Psychiatry, 69, e69e87.
Sarkis, S.M., Sarkis, E.H., Marshall, D., & Archer, J. (2005). Self-regulation and inhibition in comorbid ADHD children: An evaluation of executive functions. Journal of Attention Disorders, 8(3), 96108.
Scarpa, A., Haden, S.C., & Tanaka, A. (2010). Being hot-tempered: Autonomic, emotional, and behavioral distinctions between childhood reactive and proactive aggression. Biological Psychiatry, 84, 488496.
Scheres, A., Tontsch, C., Thoeny, A.L., & Kaczkurkin, A. (2010). Temporal reward discounting in attention-deficit/hyperactivity disorder: The contribution of symptom domains, reward magnitude, and session length. Biological Psychiatry, 67(7), 641648.
Seidman, L.J., Biederman, J., Monuteaux, M.C., Valera, E., Doyle, A.E., & Faraone, S.V. (2005). Impact of gender and age on executive functioning: Do girls and boys with and without attention deficit hyperactivity disorder differ neuropsychologically in preteen and teenage years? Developmental Neuropsychology, 27(1), 79105.
Shiels, K., Hawk, L.W. Jr., Reynolds, B., Mazzullo, R.J., Rhodes, J.D., Pelham, W.E. Jr., &Gangloff, B.P. (2009). Effects of methylphenidate on discounting of delayed rewards in attention deficit/hyperactivity disorder. Experimental and Clinical Psychopharmacology, 17(5), 291301.
Skogli, E.W., Egeland, J., Andersen, P.N., Hovik, K.T., & Øie, M. (2014). Few differences in hot and cool executive functions in children and adolescents with combined and inattentive subtypes of ADHD. Child Neuropsychology, 20, 162181. doi:10.1080/09297049.2012.753998.
Solanto, M.V., Abikoff, H., Sonuga-Barke, E., Schachar, R., Logan, G.D., Wigal, T., & Turkel, E. (2001). The ecological validity of delay aversion and response inhibition as measures of impulsivity in AD/HD: A supplement to the NIMH multimodal treatment study of AD/HD. Journal of Abnormal Child Psychology, 29, 215228.
Sonuga-Barke, E.J. (2003). The dual pathway model of AD/HD: An elaboration of neuro-developmental characteristics. Neuroscience & Biobehavioral Reviews, 27(7), 593604.
Thorell, L.B., & Wåhlstedt, C. (2006). Executive functioning deficits in relation to symptoms of ADHD and/or ODD in preschool children. Infant and Child Development, 15(5), 503518.
Weyandt, L.L., & Willis, W.G. (1994). Executive functions in school‐aged children: Potential efficacy of tasks in discriminating clinical groups. Developmental Neuropsychology, 10(1), 2738.
Willcutt, E.G., Doyle, A.E., Nigg, J.T., Faraone, S.V., & Pennington, B.F. (2005). A meta-analytic review of the executive function theory of ADHD. Biological Psychiatry, 57, 13361346.
Wilson, V.B., Mitchell, S.H., Musser, E.D., Schmitt, C.F., & Nigg, J.T. (2011). Delay discounting of reward in ADHD: Application in young children. Journal of Child Psychology and Psychiatry, 52(3), 256264.
Yang, B.R., Chan, R.C.K., Gracia, N., Cao, X.Y., Zou, X.B., Jing, J., & Shum, D. (2011). Cool and hot executive functions in medication-naive attention deficit hyperactivity disorder children. Psychological Medicine, 41(12), 25932602.
Zelazo, P.D., & Carlson, S.M. (2012). Hot and cool executive function in childhood and adolescence: Development and plasticity. Child Development Perspectives, 6, 354360.
Zelazo, P.D., & Müller, U. (2011). Executive function in typical and atypical development. In U. Goswami (Ed.) The Wiley-Blackwell Handbook of Childhood Cognitive Development (2nd ed.) Oxford: Wiley-Blackwell.
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