Fengler, Sophie Liepelt-Scarfone, Inga Brockmann, Kathrin Schäffer, Eva Berg, Daniela and Kalbe, Elke 2017. Cognitive changes in prodromal Parkinson's disease: A review. Movement Disorders,
Peall, K.J. Lorentzos, M.S. Heyman, I. Tijssen, M.A.J. Owen, M.J. Dale, R.C. and Kurian, M.A. 2017. A review of psychiatric co-morbidity described in genetic and immune mediated movement disorders. Neuroscience & Biobehavioral Reviews, Vol. 80, p. 23.
Chen, Yueh-Sheng Chen, Meng-Hsiang Lu, Cheng-Hsien Chen, Pei-Chin Chen, Hsiu-Ling Yang, I-Hsiao Tsai, Nai-Wen and Lin, Wei-Che 2017. Associations among Cognitive Functions, Plasma DNA, and White Matter Integrity in Patients with Early-Onset Parkinson's Disease. Frontiers in Neuroscience, Vol. 11,
Pal, Gian D. Hall, Deborah Ouyang, Bichun Phelps, Jessica Alcalay, Roy Pauciulo, Michael W. Nichols, William C. Clark, Lorraine Mejia-Santana, Helen Blasucci, Lucia Goetz, Christopher G. Comella, Cynthia Colcher, Amy Gan-Or, Ziv Rouleau, Guy A. and Marder, Karen 2016. Genetic and Clinical Predictors of Deep Brain Stimulation in Young-Onset Parkinson's Disease. Movement Disorders Clinical Practice, Vol. 3, Issue. 5, p. 465.
Makovac, Elena Cercignani, Mara Serra, Laura Torso, Mario Spanò, Barbara Petrucci, Simona Ricciardi, Lucia Ginevrino, Monia Caltagirone, Carlo Bentivoglio, Anna Rita Valente, Enza Maria Bozzali, Marco and Herholz, Karl 2016. Brain Connectivity Changes in Autosomal Recessive Parkinson Disease: A Model for the Sporadic Form. PLOS ONE, Vol. 11, Issue. 10, p. e0163980.
Anderson-Mooney, Amelia J. Guller, Leila Combs, Hannah L. and Dunham, Kathryn J. 2016. Neurocognitive & neuropsychiatric phenotypes of PARK2-associated early-onset Parkinson’s disease in two siblings. Clinical Neurology and Neurosurgery, Vol. 142, p. 137.
Haddad, Dominik and Nakamura, Ken 2015. Understanding the susceptibility of dopamine neurons to mitochondrial stressors in Parkinson's disease. FEBS Letters, Vol. 589, Issue. 24PartA, p. 3702.
Alcalay, Roy N. Mejia-Santana, Helen Mirelman, Anat Saunders-Pullman, Rachel Raymond, Deborah Palmese, Christina Caccappolo, Elise Ozelius, Laurie Orr-Urtreger, Avi Clark, Lorraine Giladi, Nir Bressman, Susan and Marder, Karen 2015. Neuropsychological performance in LRRK2 G2019S carriers with Parkinson's disease. Parkinsonism & Related Disorders, Vol. 21, Issue. 2, p. 106.
Nombela, Cristina Rowe, James B. Winder-Rhodes, Sophie E. Hampshire, Adam Owen, Adrian M. Breen, David P. Duncan, Gordon W. Khoo, Tien K. Yarnall, Alison J. Firbank, Michael J. Chinnery, Patrick F. Robbins, Trevor W. O’Brien, John T. Brooks, David J. Burn, David J. and Barker, Roger A. 2014. Genetic impact on cognition and brain function in newly diagnosed Parkinson’s disease: ICICLE-PD study. Brain, Vol. 137, Issue. 10, p. 2743.
Halliday, Glenda M. Leverenz, James B. Schneider, Jay S. and Adler, Charles H. 2014. The neurobiological basis of cognitive impairment in Parkinson's disease. Movement Disorders, Vol. 29, Issue. 5, p. 634.
Sharp, Madeleine E. Marder, Karen S. Côté, Lucien Clark, Lorraine N. Nichols, William C. Vonsattel, Jean-Paul and Alcalay, Roy N. 2014. Parkinson's disease with Lewy bodies associated with a heterozygousPARKINdosage mutation. Movement Disorders, Vol. 29, Issue. 4, p. 566.
The cognitive profile of early onset Parkinson’s disease (EOPD) has not been clearly defined. Mutations in the parkin gene are the most common genetic risk factor for EOPD and may offer information about the neuropsychological pattern of performance in both symptomatic and asymptomatic mutation carriers. EOPD probands and their first-degree relatives who did not have Parkinson’s disease (PD) were genotyped for mutations in the parkin gene and administered a comprehensive neuropsychological battery. Performance was compared between EOPD probands with (N = 43) and without (N = 52) parkin mutations. The same neuropsychological battery was administered to 217 first-degree relatives to assess neuropsychological function in individuals who carry parkin mutations but do not have PD. No significant differences in neuropsychological test performance were found between parkin carrier and noncarrier probands. Performance also did not differ between EOPD noncarriers and carrier subgroups (i.e., heterozygotes, compound heterozygotes/homozygotes). Similarly, no differences were found among unaffected family members across genotypes. Mean neuropsychological test performance was within normal range in all probands and relatives. Carriers of parkin mutations, whether or not they have PD, do not perform differently on neuropsychological measures as compared to noncarriers. The cognitive functioning of parkin carriers over time warrants further study. (JINS, 2011, 17, 1–10)
Email your librarian or administrator to recommend adding this journal to your organisation's collection.
Full text views reflects the number of PDF downloads, PDFs sent to Google Drive, Dropbox and Kindle and HTML full text views.
* Views captured on Cambridge Core between September 2016 - 16th January 2018. This data will be updated every 24 hours.