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Neuropsychological studies of asymptomatic Human Immunodeficiency Virus-Type-1 infected individuals

Published online by Cambridge University Press:  26 February 2009

Desirée A. White ,
Robert K. Heaton  and
Andreas U. Monsch
Desirée A. White
Affiliation:
Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093
Robert K. Heaton
Affiliation:
Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093
Andreas U. Monsch
Affiliation:
Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093 San Diego Department of Veterans Affairs Medical Center, San Diego, CA 92161
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Abstract

The current review was conducted to address the ongoing debate regarding the presence or absence of neuropsychological impairment in asymptomatic HIV-Type 1 (HIV-1) seropositive individuals. Results were summarized from 57 studies that compared the performances of seropositive asymptomatic and seronegative individuals. Overall, the differences observed between median rates of impairment for asymptomatic (35%) and seronegative (12%) groups provided the clearest indication of deficits in asymptomatics. In addition, five variables were examined as possible contributors to inconsistencies found in the literature: mode of infection, test battery type, test battery size, sample size, and method of data analysis. Of these variables, only mode of infection and test battery size appeared to substantially influence the outcome of the studies reviewed with regard to identifying neuropsychological impairment in asymptomatics. (JINS, 1995, I, 304–315.)

Keywords

Human Immunodeficiency VirusNeuropsychologyAsymptomatic

Information

Type
Critical Review
Information
Journal of the International Neuropsychological Society , Volume 1 , Issue 3 , May 1995 , pp. 304 - 315
Copyright
Copyright © The International Neuropsychological Society 1995

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