The National Institutes of Health (NIH) Magnetic Resonance Imaging
(MRI) Study of Normal Brain Development is a landmark study in which
structural and metabolic brain development and behavior are followed
longitudinally from birth to young adulthood in a population-based sample
of healthy children. The neuropsychological assessment protocol for
children aged 6 to 18 years is described and normative data are presented
for participants in that age range (N = 385). For many measures,
raw score performance improved steeply from 6 to 10 years, decelerating
during adolescence. Sex differences were documented for Block Design (male
advantage), CVLT, Pegboard and Coding (female advantage). Household income
predicted IQ and achievement, as well as externalizing problems and social
competence, but not the other cognitive or behavioral measures.
Performance of this healthy sample was generally better than published
norms. This linked imaging-clinical/behavioral database will be an
invaluable public resource for researchers for many years to come.
(JINS, 2007, 13, 729–746.)
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