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Physical Activity Is Positively Associated with Episodic Memory in Aging

  • Scott M. Hayes (a1) (a2), Michael L. Alosco (a1) (a3), Jasmeet P. Hayes (a4) (a5), Margaret Cadden (a6), Kristina M. Peterson (a1), Kelly Allsup (a7), Daniel E. Forman (a7) (a8), Reisa A. Sperling (a9) (a10) (a11) (a12) and Mieke Verfaellie (a1)...
Abstract
Abstract

Aging is associated with performance reductions in executive function and episodic memory, although there is substantial individual variability in cognition among older adults. One factor that may be positively associated with cognition in aging is physical activity. To date, few studies have objectively assessed physical activity in young and older adults, and examined whether physical activity is differentially associated with cognition in aging. Young (n=29, age 18–31 years) and older adults (n=31, ages 55–82 years) completed standardized neuropsychological testing to assess executive function and episodic memory capacities. An experimental face-name relational memory task was administered to augment assessment of episodic memory. Physical activity (total step count and step rate) was objectively assessed using an accelerometer, and hierarchical regressions were used to evaluate relationships between cognition and physical activity. Older adults performed more poorly on tasks of executive function and episodic memory. Physical activity was positively associated with a composite measure of visual episodic memory and face-name memory accuracy in older adults. Physical activity associations with cognition were independent of sedentary behavior, which was negatively correlated with memory performance. Physical activity was not associated with cognitive performance in younger adults. Physical activity is positively associated with episodic memory performance in aging. The relationship appears to be strongest for face-name relational memory and visual episodic memory, likely attributable to the fact that these tasks make strong demands on the hippocampus. The results suggest that physical activity relates to cognition in older, but not younger adults. (JINS, 2015, 21, 780–790)

Copyright
Corresponding author
Correspondence and reprint requests to: Scott M. Hayes, Memory Disorders Research Center (151A), VA Boston Healthcare System, 150 South Huntington Avenue, Boston, MA 02130. E-mail: smhayes@bu.edu
References
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Barnes D.E., Blackwell T., Stone K.L., Goldman S.E., Hillier T., & Yaffe K. (2008). Cognition in older women: The importance of daytime movement. Journal of the American Geriatric Society, 56(9), 16581664. doi:JGS1841 [pii] 10.1111/j.1532-5415.2008.01841.x
Benedict R. (1997). Brief Visuospatial Memory Test-Revised: Professional Manual. Lutz, FL: Psychological Assessment Resources, Inc.
Bherer L., Erickson K.I., & Liu-Ambrose T. (2013). A review of the effects of physical activity and exercise on cognitive and brain functions in older adults. Journal of Aging Research, 2013, 657508. doi:10.1155/2013/657508
Brown B.M., Peiffer J.J., Sohrabi H.R., Mondal A., Gupta V.B., & Rainey-Smith S.R. (2012). Intense physical activity is associated with cognitive performance in the elderly. Translational Psychiatry, 2, e191. doi:tp2012118 [pii]10.1038/tp.2012.118
Buchman A.S., Boyle P.A., Yu L., Shah R.C., Wilson R.S., & Bennett D.A. (2012). Total daily physical activity and the risk of AD and cognitive decline in older adults. Neurology, 78(17), 13231329. doi:WNL.0b013e3182535d35 [pii]10.1212/WNL.0b013e3182535d35
Buchman A.S., Wilson R.S., & Bennett D.A. (2008). Total daily activity is associated with cognition in older persons. American Journal of Geriatric Psychiatry, 16(8), 697701. doi:16/8/697 [pii] 10.1097/JGP.0b013e31817945f6
Caspersen C.J., Powell K.E., & Christenson G.M. (1985). Physical activity, exercise, and physical fitness: Definitions and distinctions for health-related research. Public Health Report, 100(2), 126131.
Colcombe S., & Kramer A.F. (2003). Fitness effects on the cognitive function of older adults: A meta-analytic study. Psychological Science, 14(2), 125130. doi:10.1111/1467-9280.t01-1-01430
Colcombe S.J., Kramer A.F., Erickson K.I., Scalf P., McAuley E., & Cohen N.J. (2004). Cardiovascular fitness, cortical plasticity, and aging. Proceedings of the National Academy of Sciences of the United States of America, 101(9), 33163321.
Cotman C.W., Berchtold N.C., & Christie L.A. (2007). Exercise builds brain health: Key roles of growth factor cascades and inflammation. Trends in Neurosciences, 30(9), 464472. doi:10.1016/J.Tins.2007.06.011
Craft L.L., Zderic T.W., Gapstur S.M., Vaniterson E.H., Thomas D.M., & Siddique J. (2012). Evidence that women meeting physical activity guidelines do not sit less: An observational inclinometry study. The International Journal of Behavioral Nutrition and Physical Activity, 9, 122. doi:1479-5868-9-122 [pii]10.1186/1479-5868-9-122
Delis D., Kaplan E., & Kramer J. (2001). Delis-Kaplan Executive Function System. San Antonio, TX: The Psychological Corporation.
Delis D., Kramer J., Kaplan E., & Ober B. (2000). California Verbal Learning Test-Second Edition: Adult Version. San Antonio, TX: The Psychological Coporation.
Freedson P., Bowles H.R., Troiano R., & Haskell W. (2012). Assessment of physical activity using wearable monitors: Recommendations for monitor calibration and use in the field. Medicine and Science in Sports and Exercise, 44(1 Suppl 1), S1S4. doi:10.1249/MSS.0b013e3182399b7e 00005768-201201001-00001 [pii]
Freedson P.S., Melanson E., & Sirard J. (1998). Calibration of the Computer Science and Applications, Inc. accelerometer. Medicine and Science in Sports and Exercise, 30(5), 777781.
Giovanello K.S., Verfaellie M., & Keane M.M. (2003). Disproportionate deficit in associative recognition relative to item recognition in global amnesia. Cognitive, Affectice and Behavioral Neuroscience, 3(3), 186194. doi:10.3758/CABN.3.3.186
Goh J.O., An Y., & Resnick S.M. (2012). Differential trajectories of age-related changes in components of executive and memory processes. Psycholog and Aging, 27(3), 707719. doi:2011-30106-001 [pii]10.1037/a0026715.
Haskell W.L., Lee I.M., Pate R.R., Powell K.E., Blair S.N., & Franklin B.A. (2007). Physical activity and public health: Updated recommendation for adults from the American College of Sports Medicine and the American Heart Association. Medicine and Science in Sports and Exercise, 39(8), 14231434. doi:10.1249/mss.0b013e3180616b2700005768-200708000-00027 [pii].
Hayes S.M., Buchler N., Stokes J., Kragel J., & Cabeza R. (2011). Neural correlates of confidence during item recognition and source memory retrieval: Evidence for both dual-process and strength memory theories. Journal of Cognitive Neuroscience, 23(12), 39593971. doi:10.1162/jocn_a_00086
Hayes S.M., Forman D.E., & Verfaellie M. (2014). Cardiorespiratory fitness is associated with cognitive performance in older but not younger adults. The Journals of Gerontology Series B Psychological Sciences and Social Sciences (doi:gbu167 [pii] 10.1093/geronb/gbu167
Hayes S.M., Hayes J.P., Cadden M., & Verfaellie M. (2013). A review of cardiorespiratory fitness-related neuroplasticity in the aging brain. Frontiers in Aging Neuroscience, 5, 31. doi:10.3389/fnagi.2013.00031
Hayes S.M., Salat D.H., Forman D.E., Sperling R.A., & Verfaellie M. (2015). Cardiorespiratory fitness is associated with white matter integrity in aging. Annals of Clinical and Translational Neurology, 2(6), 688698. doi:10.1002/acn3.204
Hotting K., & Roder B. (2013). Beneficial effects of physical exercise on neuroplasticity and cognition. Neuroscience and Biobehavioral Reviews, 37(9 Pt B), 22432257. doi:S0149-7634(13)00101-2 [pii]10.1016/j.neubiorev.2013.04.005
Moscovitch M. (1992). Memory and working-with-memory: A component process model based on modules and central systems. Journal of Cognitive Neuroscience, 4(3), 257267. doi:10.1162/jocn.1992.4.3.257
Naveh-Benjamin M. (2000). Adult age differences in memory performance: Tests of an associative deficit hypothesis. Journal of Experimental Psychology. Learning, Memory, and Cognition, 26(5), 11701187. doi:10.1037/0278-7393.26.5.1170
Nichol K., Deeny S.P., Seif J., Camaclang K., & Cotman C.W. (2009). Exercise improves cognition and hippocampal plasticity in APOE epsilon 4 mice. Alzheimers & Dementia, 5(4), 287294. doi:10.1016/J.Jalz.2009.02.006
Old S.R., & Naveh-Benjamin M. (2008). Differential effects of age on item and associative measures of memory: A meta-analysis. Psychology and Aging, 23(1), 104118. doi:10.1037/0882-7974.23.1.104|issn 0882-7974
Pescatello L.S., American College of Sports Medicine (2014). ACSM’s guidelines for exercise testing and prescription (9th ed.). Wolters Kluwer/Lippincott Williams & Wilkins Health.
Prakash R.S., Voss M.W., Erickson K.I., & Kramer A.F. (2015). Physical activity and cognitive vitality. Annual Review of Psychology, 66, 769797. doi:10.1146/annurev-psych-010814-015249
Prince S.A., Adamo K.B., Hamel M.E., Hardt J., Connor Gorber S., & Tremblay M. (2008). A comparison of direct versus self-report measures for assessing physical activity in adults: A systematic review. The International Journal of Behavioral Nutrition and Physical Activity, 5, 56. doi:1479-5868-5-56 [pii] 10.1186/1479-5868-5-56
Reese C.M., Cherry K.E., & Norris L.E. (1999). Practical memory concerns of older adults. Journal of Clinical Geropsychology, 5(4), 231244. doi:10.1023/A:1022984622951
Rzewnicki R., Vanden Auweele Y., & De Bourdeaudhuij I. (2003). Addressing overreporting on the International Physical Activity Questionnaire (IPAQ) telephone survey with a population sample. Public Health Nutrition, 6(3), 299305. doi:10.1079/PHN2002427 S1368980003000399 [pii].
Shepard R.J. (2003). Limits to the measurement of habitual physical activity by questionnaires. British Journal of Sports Medicine, 37, 197206.
Shimamura A.P., Berry J.M., Mangels J.A., Rusting C.L., & Jurica P.J. (1995). Memory and Cognitive-abilities in university professors - Evidence for successful aging. Psychological Science, 6(5), 271277.
Smith P.J., Blumenthal J.A., Hoffman B.M., Cooper H., Strauman T.A., & Welsh-Bohmer K. (2010). Aerobic exercise and neurocognitive performance: A meta-analytic review of randomized controlled trials. Psychosomatic Medicine, 72(3), 239252. doi:10.1097/Psy.0b013e3181d14633
Sofi F., Valecchi D., Bacci D., Abbate R., Gensini G.F., & Casini A. (2011). Physical activity and risk of cognitive decline: A meta-analysis of prospective studies. Journal of Internal Medicine, 269(1), 107117. doi:10.1111/j.1365-2796.2010.02281.x
Sperling R., Chua E., Cocchiarella A., Rand-Giovannetti E., Poldrack R., & Schacter D.L. (2003). Putting names to faces: Successful encoding of associative memories activates the anterior hippocampal formation. Neuroimage, 20(2), 14001410. doi:10.1016/S1053-8119(03)00391-4S1053811903003914 [pii].
Tudor-Locke C., & Bassett D.R. Jr. (2004). How many steps/day are enough? Preliminary pedometer indices for public health. Sports Medicine, 34(1), 18. doi:3411 [pii].
Tudor-Locke C., & Schuna J.M. Jr. (2012). Steps to preventing type 2 diabetes: Exercise, walk more, or sit less? Frontiers in Endocrinology (Lausanne), 3, 142. doi:10.3389/fendo.2012.00142
van Praag H., Shubert T., Zhao C.M., & Gage F.H. (2005). Exercise enhances learning and hippocampal neurogenesis in aged mice. Journal of Neuroscience, 25(38), 86808685. doi:10.1523/Jneurosci.1731-05-2005
Vaynman S., & Gomez-Pinilla F. (2006). Revenge of the “sit”: How lifestyle impacts neuronal and cognitive health through molecular systems that interface energy metabolism with neuronal plasticity. Journal of Neuroscience Research, 84(4), 699715. doi:10.1002/jnr.20979
Voss M.W., Carr L.J., Clark R., & Weng T. (2014). Revenge of the “sit” II: Does lifestyle impact neuronal and cognitive health through distinct mechanisms associated with sedentary behavior and physical activity? Mental Health and Physical Activity. doi:http://dx.doi.org/10.1016/j.mhpa.2014.01.001
Voss M.W., Vivar C., Kramer A.F., & van Praag H. (2013). Bridging animal and human models of exercise-induced brain plasticity. Trends in Cognitive Science, 17(10), 525544. doi:S1364-6613(13)00166-6 [pii]10.1016/j.tics.2013.08.001.
Wechsler D. (1997). Wechsler Adult Intelligence Scale-Third Edition. San Antonio, TX: The Psychological Corporation.
Wechsler D. (1997). Wechsler Memory Scale-Third Edition. San Antonio, TX: The Psychological Corporation.
Wilbur J., Marquez D.X., Fogg L., Wilson R.S., Staffileno B.A., & Hoyem R.L. (2012). The relationship between physical activity and cognition in older Latinos. The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences, 67(5), 525534. doi:gbr137 [pii]10.1093/geronb/gbr137
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