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Predicting Fatigue 12 Months after Child Traumatic Brain Injury: Child Factors and Postinjury Symptoms

  • Alison Crichton (a1) (a2) (a3), Ed Oakley (a1) (a4) (a5), Franz E Babl (a1) (a4) (a5), Mardee Greenham (a1) (a3), Stephen Hearps (a1), Carmel Delzoppo (a1) (a5), Miriam H. Beauchamp (a6) (a7), James S. Hutchison (a8) (a9) (a10), Anne-Marie Guerguerian (a8), Kathy Boutis (a8) (a10) and Vicki Anderson (a1) (a3) (a5)...
Abstract

Objectives: Fatigue is a common and persisting symptom after childhood brain injury. This study examined whether child characteristics and symptomatology preinjury or 6 months postinjury (pain, sleep, and mood, inattention) predicted fatigue at 12months postinjury. Methods: Parents of 79 children (0–18 years) rated fatigue at 12 months after injury on a multidimensional scale (general, sleep/rest, and cognitive). Demographic and clinical data were collected at injury. Parents rated child sleep, pain, physical/motor function, mood, and inattention at injury (preinjury description), and 6 months postinjury. Children were divided into two traumatic brain injury severity groups: mild TBI (n=57) and moderate/severe TBI (n=27). Hierarchical regression models were used to examine (i) preinjury factors and (ii) symptoms 6 months postinjury predictive of fatigue (general, sleep/rest, and cognitive) at 12 months postinjury. Results: Sleep/rest fatigue was predicted by preinjury fatigue (7% of variance) and psychological symptoms preinjury (10% of variance). General fatigue was predicted by physical/motor symptoms (27%), sleep (10%) and mood symptoms (9%) 6 months postinjury. Sleep/rest fatigue was predicted by physical/motor symptoms (10%), sleep symptoms (13%) and mood symptoms (9%) 6 months postinjury. Cognitive fatigue was predicted by physical/motor symptoms (17%) 6 months postinjury. Conclusions: Preinjury fatigue and psychological functioning identified those at greatest risk of fatigue 12 months post-TBI. Predictors of specific fatigue domains at 12 months differed across each of the domains, although consistently included physical/motor function as well as sleep and mood symptoms postinjury. (JINS, 2018, 24, 224–236)

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Corresponding author
Correspondence and reprint requests to: Alison Crichton, Murdoch Childrens Research Institute, 50 Flemington Road, Parkville, Victoria, 3052, Australia. E-mail: ali.crichton@mcri.edu.au
References
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