Skip to main content
×
Home
    • Aa
    • Aa

Self-perceived Difficulties in Everyday Function Precede Cognitive Decline among Older Adults in the ACTIVE Study

  • Sarah Tomaszewski Farias (a1), Tania Giovannetti (a2), Brennan R. Payne (a3), Michael Marsiske (a4), George W. Rebok (a5), K. Warner Schaie (a6), Kelsey R. Thomas (a7), Sherry L. Willis (a6), Joseph M. Dzierzewski (a8), Frederick Unverzagt (a9) and Alden L. Gross (a10)...
Abstract
Abstract

Objectives: Careful characterization of how functional decline co-evolves with cognitive decline in older adults has yet to be well described. Most models of neurodegenerative disease postulate that cognitive decline predates and potentially leads to declines in everyday functional abilities; however, there is mounting evidence that subtle decline in instrumental activities of daily living (IADLs) may be detectable in older individuals who are still cognitively normal. Methods: The present study examines how the relationship between change in cognition and change in IADLs are best characterized among older adults who participated in the ACTIVE trial. Neuropsychological and IADL data were analyzed for 2802 older adults who were cognitively normal at study baseline and followed for up to 10 years. Results: Findings demonstrate that subtle, self-perceived difficulties in performing IADLs preceded and predicted subsequent declines on cognitive tests of memory, reasoning, and speed of processing. Conclusions: Findings are consistent with a growing body of literature suggesting that subjective changes in everyday abilities can be associated with more precipitous decline on objective cognitive measures and the development of mild cognitive impairment and dementia. (JINS, 2017, 23, 1–9)

Copyright
Corresponding author
Correspondence and reprint requests to: Sarah Tomaszewski Farias, University of California, Davis, Department of Neurology 4860 Y Street, suite 3700 Sacramento CA 95817. E-mail: farias@ucdavis.edu
Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Journal of the International Neuropsychological Society
  • ISSN: 1355-6177
  • EISSN: 1469-7661
  • URL: /core/journals/journal-of-the-international-neuropsychological-society
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Keywords:

Type Description Title
WORD
Supplementary Materials

Tomaszewski Farias supplementary material
Table S6

 Word (17 KB)
17 KB
WORD
Supplementary Materials

Tomaszewski Farias supplementary material
Table S8

 Word (15 KB)
15 KB
WORD
Supplementary Materials

Tomaszewski Farias supplementary material
Table S1

 Word (15 KB)
15 KB
WORD
Supplementary Materials

Tomaszewski Farias supplementary material
Table S3

 Word (20 KB)
20 KB
WORD
Supplementary Materials

Tomaszewski Farias supplementary material
Table S5

 Word (16 KB)
16 KB
WORD
Supplementary Materials

Tomaszewski Farias supplementary material
Table S2

 Word (18 KB)
18 KB
WORD
Supplementary Materials

Tomaszewski Farias supplementary material
Table S4

 Word (15 KB)
15 KB
WORD
Supplementary Materials

Tomaszewski Farias supplementary material
Table S7

 Word (17 KB)
17 KB

Metrics

Altmetric attention score

Full text views

Total number of HTML views: 3
Total number of PDF views: 52 *
Loading metrics...

Abstract views

Total abstract views: 257 *
Loading metrics...

* Views captured on Cambridge Core between 11th August 2017 - 26th September 2017. This data will be updated every 24 hours.