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Stroop performance in drug users classified by HIV and hepatitis C virus serostatus

Published online by Cambridge University Press:  01 March 2004

EILEEN M. MARTIN ,
RICHARD M. NOVAK ,
MICHAEL FENDRICH ,
JASMIN VASSILEVA ,
RAUL GONZALEZ ,
SILVANA GRBESIC ,
GERALD NUNNALLY  and
LISA SWOROWSKI
EILEEN M. MARTIN
Affiliation:
Department of Psychiatry, University of Illinois, Chicago, Illinois Chicago Veterans Healthcare System-West Side Division, Chicago Illinois
RICHARD M. NOVAK
Affiliation:
Department of Medicine, Section of Infectious Diseases, University of Illinois, Chicago, Illinois
MICHAEL FENDRICH
Affiliation:
Department of Psychiatry, University of Illinois, Chicago, Illinois
JASMIN VASSILEVA
Affiliation:
Department of Psychiatry, University of Illinois, Chicago, Illinois
RAUL GONZALEZ
Affiliation:
Department of Psychiatry, University of Illinois, Chicago, Illinois Joint Doctoral Program, San Diego State University, San Diego, California University of California-San Diego, San Diego, California
SILVANA GRBESIC
Affiliation:
Department of Psychiatry, University of Illinois, Chicago, Illinois
GERALD NUNNALLY
Affiliation:
Chicago Veterans Healthcare System-West Side Division, Chicago Illinois
LISA SWOROWSKI
Affiliation:
Department of Psychiatry, University of Illinois, Chicago, Illinois
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Extract

Hepatitis C virus (HCV) can be detected in the brain (Radkowski et al., 2002) and investigators speculate that HCV has neuroinvasive properties (Forton et al., 2003) with direct effects on cerebral function. MRS studies show that the basal ganglia and white matter of individuals with HCV have abnormal choline/creatine ratios, indicating CNS inflammation or infection (Forton et al., 2003). Patients with HCV show defects in working memory and information processing speed (Forton et al., 2003; Hilsabeck et al., 2002), similar to patients with basal ganglia disorders and HIV (e.g., Heaton et al., 1995).

Information

Type
RESEARCH LETTER
Information
Journal of the International Neuropsychological Society , Volume 10 , Issue 2 , March 2004 , pp. 298 - 300
Copyright
© 2004 The International Neuropsychological Society

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References

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