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Two Immersive Virtual Reality Tasks for the Assessment of Spatial Orientation in Older Adults with and Without Cognitive Impairment: Concurrent Validity, Group Comparison, and Accuracy Results

Published online by Cambridge University Press:  03 June 2021

Raquel Quimas Molina da Costa Open the ORCID record for Raquel Quimas Molina da Costa [Opens in a new window] ,
José Eduardo Pompeu ,
Emerson Moretto ,
Juliana Magalhães Silva ,
Michelle Didone dos Santos ,
Ricardo Nitrini  and
Sonia Maria Dozzi Brucki
Raquel Quimas Molina da Costa*
Affiliation:
Departamento de Neurologia, Faculdade de Medicina da Universidade de São Paulo, Cerqueira César, SP, Brazil
José Eduardo Pompeu
Affiliation:
Departamento de Fisioterapia, Fonoaudiologia e Terapia ocupacional da Faculdade de Medicina da Universidade de São Paulo, Butantã, SP, Brazil
Emerson Moretto
Affiliation:
Departamento de Engenharia de Sistemas Eletrônicos, Escola Politécnica, Universidade de São Paulo, Butantã, SP, Brazil
Juliana Magalhães Silva
Affiliation:
Departamento de Fisioterapia, Fonoaudiologia e Terapia ocupacional da Faculdade de Medicina da Universidade de São Paulo, Butantã, SP, Brazil
Michelle Didone dos Santos
Affiliation:
Departamento de Fisioterapia, Fonoaudiologia e Terapia ocupacional da Faculdade de Medicina da Universidade de São Paulo, Butantã, SP, Brazil
Ricardo Nitrini
Affiliation:
Departamento de Neurologia, Faculdade de Medicina da Universidade de São Paulo, Cerqueira César, SP, Brazil
Sonia Maria Dozzi Brucki
Affiliation:
Departamento de Neurologia, Faculdade de Medicina da Universidade de São Paulo, Cerqueira César, SP, Brazil
*
*Correspondence and reprint requests to: Raquel Quimas Molina da Costa, R. Diniz Cordeiro 30, 3rd floor, Botafogo, Rio de Janeiro – RJ, 22281-100, Brazil. Email: raquel_quimas@hotmail.com. Phone: +55 21 3883-6000
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Abstract

Objective:

Spatial disorientation is common in Alzheimer’s disease (AD), Mild Cognitive Impairment (MCI), and preclinical individuals with AD biomarkers. However, traditional neuropsychological tests lack ecological validity for the assessment of spatial orientation and to date, there is still no gold standard. The current study aimed to determine the validity and accuracy of two virtual reality tasks for the assessment of spatial orientation.

Methods:

We adapted two spatial orientation tasks to immersive virtual environments: a “survey to route” task in which participants had to transfer information from a map to their body position within a maze [Spatial Orientation in Immersive Virtual Environment Test (SOIVET) Maze], and an allocentric-type, route learning task, with well-established topographic landmarks (SOIVET Route). A total of 19 MCI patients and 29 cognitively healthy older adults aged 61–92 participated in this study. Regular neuropsychological assessments were used for correlation analysis and participant performances were compared between groups. Receiver Operating Characteristic (ROC) curve analysis was performed for accuracy.

Results:

The SOIVET Maze correlated with measures of visuoperception, mental rotation, and planning, and was not related to age, educational level, or technology use profile. The SOIVET Route immediate correlated with measures of mental rotation, memory, and visuoconstruction, and was influenced only by education. Both tasks significantly differentiated MCI and control groups, and demonstrated moderate accuracy for the MCI diagnosis.

Conclusion:

Traditional neuropsychological assessment presents limitations and immersive environments allow for the reproduction of complex cognitive processes. The two immersive virtual reality tasks are valid tools for the assessment of spatial orientation and should be considered for cognitive assessments of older adults.

Keywords

Cognitive dysfunctionAlzheimer’s diseaseSpatial navigationValidation studiesBiomedical technologyNeuropsychological tests
Type
Regular Research
Information
Journal of the International Neuropsychological Society , Volume 28 , Issue 5 , May 2022 , pp. 460 - 472
Copyright
Copyright © INS. Published by Cambridge University Press, 2021

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