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Two-domain DNA strand displacement

Published online by Cambridge University Press:  28 February 2013

LUCA CARDELLI
LUCA CARDELLI*
Affiliation:
Microsoft Research, J. J. Thomson Avenue, Cambridge, CB3 0FB, United Kingdom Email: luca@microsoft.com
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Abstract

We investigate the computing power of a restricted class of DNA strand displacement structures: those that are made of double strands with nicks (interruptions) in the top strand. To preserve this structural invariant, we impose restrictions on the single strands they interact with: we consider only two-domain single strands consisting of one toehold domain and one recognition domain. We study fork and join signal processing gates based on these structures, and show that these systems are amenable to formalisation and mechanical verification.

Type
Paper
Information
Mathematical Structures in Computer Science , Volume 23 , Special Issue 2: Developments In Computational Models 2010 , April 2013 , pp. 247 - 271
Copyright
Copyright © Cambridge University Press 2013

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