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Cryptosporidium species in humans and animals: current understanding and research needs

  • UNA RYAN (a1), RONALD FAYER (a2) and LIHUA XIAO (a3)
Summary

Cryptosporidium is increasingly recognized as one of the major causes of moderate to severe diarrhoea in developing countries. With treatment options limited, control relies on knowledge of the biology and transmission of the members of the genus responsible for disease. Currently, 26 species are recognized as valid on the basis of morphological, biological and molecular data. Of the nearly 20 Cryptosporidium species and genotypes that have been reported in humans, Cryptosporidium hominis and Cryptosporidium parvum are responsible for the majority of infections. Livestock, particularly cattle, are one of the most important reservoirs of zoonotic infections. Domesticated and wild animals can each be infected with several Cryptosporidium species or genotypes that have only a narrow host range and therefore have no major public health significance. Recent advances in next-generation sequencing techniques will significantly improve our understanding of the taxonomy and transmission of Cryptosporidium species, and the investigation of outbreaks and monitoring of emerging and virulent subtypes. Important research gaps remain including a lack of subtyping tools for many Cryptosporidium species of public and veterinary health importance, and poor understanding of the genetic determinants of host specificity of Cryptosporidium species and impact of climate change on the transmission of Cryptosporidium.

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Corresponding author
* Corresponding author: School of Veterinary and Life Sciences, Murdoch University, Murdoch, Western Australia, 6150 Australia. E-mail: Una.Ryan@murdoch.edu.au
References
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Abal-Fabeiro, J. L., Maside, X., Bello, X., Llovo, J. and Bartolomé, C. (2013). Multilocus patterns of genetic variation across Cryptosporidium species suggest balancing selection at the gp60 locus. Molecular Ecology 22, 47234732.
Abd El Kader, N. M., Blanco, M. A., Ali-Tammam, M., Abd El Ghaffar Ael, R., Osman, A., El Sheikh, N., Rubio, J. M. and de Fuentes, I. (2012). Detection of Cryptosporidium parvum and Cryptosporidium hominis in human patients in Cairo, Egypt. Parasitology Research 110, 161166.
Abeywardena, H., Jex, A. R., Nolan, M. J., Haydon, S. R., Stevens, M. A., McAnulty, R. W. and Gasser, R. B. (2012). Genetic characterisation of Cryptosporidium and Giardia from dairy calves: discovery of species/genotypes consistent with those found in humans. Infection Genetics and Evolution 12, 19841993.
Abeywardena, H., Jex, A. R., Koehler, A. V., Rajapakse, R. J., Udayawarna, K., Haydon, S. R., Stevens, M. A. and Gasser, R. B. (2014). First molecular characterization of Cryptosporidium and Giardia from bovines (Bos taurus and Bubalus bubalis) in Sri Lanka: unexpected absence of C. parvum from pre-weaned calves. Parasites and Vectors 7, 75.
Adamu, H., Petros, B., Zhang, G., Kassa, H., Amer, S., Ye, J., Feng, Y. and Xiao, L. (2014). Distribution and clinical manifestations of Cryptosporidium species and subtypes in HIV/AIDS patients in Ethiopia. PLOS Neglected Tropical Diseases 8, e2831.
Agholi, M., Hatam, G. R. and Motazedian, M. H. (2013). HIV/AIDS-associated opportunistic protozoal diarrhea. AIDS Research and Human Retroviruses 29, 3541.
Alvarez-Pellitero, P. and Sitja-Bobadilla, A. (2002). Cryptosporidium molnari n. sp. (Apicomplexa:Cryptosporidiidae) infecting two marine fish species, Sparus aurata L. and Dicentrarchus labrax L. International Journal of Parasitology 32, 10071021.
Alvarez-Pellitero, P., Quiroga, M. I., Sitja-Bobadilla, A., Redondo, M. J., Palenzuela, O., Padros, F., Vazquez, S. and Nieto, J. M. (2004). Cryptosporidium scophthalmi n. sp. (Apicomplexa: Cryptosporidiidae) from cultured turbot Scophthalmus maximus. Light and electron microscope description and histopathological study. Diseases of Aquatic Organisms 62, 133145.
Amer, S., Honma, H., Ikarashi, M., Oishi, R., Endo, M., Otawa, K. and Nakai, Y. (2009). The first detection of Cryptosporidium deer-like genotype in cattle in Japan. Parasitology Research 104, 745752.
Amer, S., Harfoush, M. and He, H. (2010). Molecular and phylogenetic analyses of Cryptosporidium SPP from dairy cattle in Egypt. Journal of the Egyptian Society for Parasitology 40, 349366.
Amer, S., Zidan, S., Adamu, H., Ye, J., Roellig, D., Xiao, L. and Feng, Y. (2013). Prevalence and characterization of Cryptosporidium spp. in dairy cattle in Nile River delta provinces, Egypt. Experimental Parasitology 135, 518523.
Anderson, D. E., Duszynski, D. W. and Marquardt, W. C. (1968). Three new coccidia (Protozoa:Telosporea) from kingsnakes, Lampropeltis spp. in Illinois, with a redescription of Eimeria zamensis Phisaux, 1921. Journal of Parasitology 54, 577581.
ANOFEL Cryptosporidium National Network (2010). Laboratory-based surveillance for Cryptosporidium in France, 2006–2009. Euro Surveillance 15, 19642.
Anonymous (2010). Annual epidemiological report on communicable diseases in Europe, revised edition 2009. European Center for Disease Prevention and Control. http://ecdc.europa.eu/en/publications/Publications/0910_SUR_Annual_Epidemiological_Report_on_Communicable_Diseases_in_Europe.pdf#page=101.
Arcay-de-Peraza, L. and Bastardo-de-San-Jose, T. (1969). Cryptosporidium ameivae sp. nov. (Coccidia, Cryptosporidiidae) del intestino delgado de Ameiva ameiva de Venezuela. Acta Cientifica Venezolana 20, 125 [conf. abstract].
Asano, Y., Karasudani, T., Okuyama, M., Takami, S., Oseto, M., Inouye, H., Yamamoto, K., Aokage, J., Saiki, N., Fujiwara, M., Shiraishi, M., Uchida, K., Saiki, H., Suzuki, M., Yamamoto, T., Udaka, M., Kan, K., Matsuura, S. and Kimura, M. (2006). An outbreak of gastroenteritis associated with Cryptosporidium meleagridis among high school students of dormitory in Ehime, Japan. Annual Report of Ehime Prefecture Institute of Public Health and Environmental Science 9, 2125.
Baldursson, S. and Karanis, P. (2011). Waterborne transmission of protozoan parasites: review of worldwide outbreaks – an update 2004–2010. Water Research 45, 66036614.
Barker, I. K. and Carbonnell, P. L. (1974). Cryptosporidium agni sp.n. from lambs, and Cryptosporidium bovis sp.n. from a calf, with observations on the oocyst. Zeitschrift fur Parasitenkunde 44, 289298.
Bass, A. L., Wallace, C. C., Yund, P. O. and Ford, T. E. (2012). Detection of Cryptosporidium sp. in two new seal species, Phoca vitulina and Cystophora cristata, and a novel Cryptosporidium genotype in a third seal species, Pagophilus groenlandicus, from the Gulf of Maine. Journal of Parasitology 98, 316322.
Berrilli, F., D'Alfonso, R., Giangaspero, A., Marangi, M., Brandonisio, O., Kabore, Y., Gle, C., Cianfanelli, C., Lauro, R. and Di Cave, D. (2012). Giardia duodenalis genotypes and Cryptosporidium species in humans and domestic animals in Cote d'Ivoire: occurrence and evidence for environmental contamination. Transactions of the Royal Society of Tropical Medicine and Hygiene 106, 191195.
Bird, R. G. (1981). Parasitological topics, a presentation volume to P. C. Garnham, FRS on the occasion of his 80th birthday. In Protozoa and Viruses. Human Cryptosporidiosis and Concomitant Viral Enteritis (ed. Canning, E. U.), Vol. 1, pp. 3947. Society for Protozoology Special Publication, Lawrence, KS, USA.
Bornay-Llinares, F. J., da Silva, A. J., Mourna, I. N., Myjap, P., Pietkiewicz, H., Kruminis-Lozowska, W., Graczak, T. K. and Pieniazek, N. J. (1999). Identification of Cryptosporidium felis in a cow by morphologic and molecular methods. Applied and Environmental Microbiology 65, 14551458.
Budu-Amoako, E., Greenwood, S. J., Dixon, B. R., Barkema, H. W., Hurnik, D., Estey, C. and McClure, J. T. (2011). Occurrence of Giardia and Cryptosporidium in pigs on Prince Edward Island, Canada. Veterinary Parasitology 184, 1824.
Budu-Amoako, E., Greenwood, S. J., Dixon, B. R., Sweet, L., Ang, L., Barkema, H. W. and McClure, J. T. (2012 a). Molecular epidemiology of Cryptosporidium and Giardia in humans on Prince Edward Island, Canada: evidence of zoonotic transmission from cattle. Zoonoses and Public Health 59, 424433.
Budu-Amoako, E., Greenwood, S. J., Dixon, B. R., Barkema, H. W. and McClure, J. T. (2012 b). Giardia and Cryptosporidium on dairy farms and the role these farms may play in contaminating water sources in Prince Edward Island, Canada. Journal of Veterinary Internal Medicine 26, 668–73.
Burnet, J. B., Ogorzaly, L., Tissier, A., Penny, C. and Cauchie, H. M. (2012). Novel quantitative TaqMan real-time PCR assays for detection of Cryptosporidium at the genus level and genotyping of major human and cattle-infecting species. Journal of Applied Microbiology 114, 12111222.
Cacciò, S. M., Sannella, A. R., Mariano, V., Valentini, S., Berti, F., Tosini, F. and Pozio, E. (2013). A rare Cryptosporidium parvum genotype associated with infection of lambs and zoonotic transmission in Italy. Veterinary Parasitology 191, 128131.
Cama, V., Gilman, R. H., Vivar, A., Ticona, E., Ortega, Y., Bern, C. and Xiao, L. (2006). Mixed Cryptosporidium infections and HIV. Emerging Infectious Diseases 12, 10251028.
Cama, V. A., Ross, J. M., Crawford, S., Kawai, V., Chavez-Valdez, R., Vargas, D., Vivar, A., Ticona, E., Navincopa, M., Williamson, J., Ortega, Y., Gilman, R. H., Bern, C. and Xiao, L. (2007). Differences in clinical manifestations among Cryptosporidium species and subtypes in HIV-infected persons. Journal of Infectious Diseases 196, 684691.
Cama, V. A., Bern, C., Roberts, J., Cabrera, L., Sterling, C. R., Ortega, Y., Gilman, R. H. and Xiao, L. (2008). Cryptosporidium species and subtypes and clinical manifestations in children, Peru. Emerging Infectious Diseases 14, 15671574.
Chalmers, R. M., Ferguson, C., Cacciò, S., Gasser, R. B., Abs EL-Osta, Y. G., Heijnen, L., Xiao, L., Elwin, K., Hadfield, S., Sinclair, M. and Stevens, M. (2005). Direct comparison of selected methods for genetic categorisation of Cryptosporidium parvum and Cryptosporidium hominis species. International Journal for Parasitology 35, 397410.
Chalmers, R. M., Elwin, K., Thomas, A. L., Guy, E. C. and Mason, B. (2009 a). Long-term Cryptosporidium typing reveals the aetiology and species-specific epidemiology of human cryptosporidiosis in England and Wales, 2000 to 2003. Euro Surveillance 14, pii: 19086.
Chalmers, R. M., Robinson, G., Elwin, K., Hadfield, S. J., Xiao, L., Ryan, U., Modha, D. and Mallaghan, C. (2009 b). Cryptosporidium sp. rabbit genotype, a newly identified human pathogen. Emerging Infectious Diseases 15, 829830.
Chalmers, R. M., Smith, R., Elwin, K., Clifton-Hadley, F. A. and Giles, M. (2011 a). Epidemiology of anthroponotic and zoonotic human cryptosporidiosis in England and Wales, 2004–2006. Epidemiology and Infection 139, 700712.
Chalmers, R. M., Smith, R. P., Hadfield, S. J., Elwin, K. and Giles, M. (2011 b). Zoonotic linkage and variation in Cryptosporidium parvum from patients in the United Kingdom. Parasitology Research 108, 13211325.
Chappell, C. L., Okhuysen, P. C., Langer-Curry, R., Widmer, G., Akiyoshi, D. E., Tanriverdi, S. and Tzipori, S. (2006). Cryptosporidium hominis: experimental challenge of healthy adults. American Journal of Tropical Medicine and Hygiene 75, 851857.
Chen, Z., Mi, R., Yu, H., Shi, Y., Huang, Y., Chen, Y., Zhou, P., Cai, Y. and Lin, J. (2011). Prevalence of Cryptosporidium spp. in pigs in Shanghai, China. Veterinary Parasitology 181, 113119.
Cinque, K., Stevens, M. A., Haydon, S. R., Jex, A. R., Gasser, R. B. and Campbell, B. E. (2008). Investigating public health impacts of deer in a protected drinking water supply watershed. Water Science and Technology 58, 127132.
Connelly, L., Craig, B. H., Jones, B. and Alexander, C. L. (2013). Genetic diversity of Cryptosporidium spp. within a remote population of Soay Sheep on St. Kilda Islands, Scotland. Applied and Environmental Microbiology 79, 22402246.
Current, W. L., Upton, S. J. and Haynes, T. B. (1986). The life cycle of Cryptosporidium baileyi n. sp. (Apicomplexa, Cryptosporidiidae) infecting chickens. Journal of Protozoology 33, 289296.
Del Chierico, F., Onori, M., Di Bella, S., Bordi, E., Petrosillo, N., Menichella, D., Caccio, S. M., Callea, F. and Putignani, L. (2011). Cases of cryptosporidiosis co-infections in AIDS patients: a correlation between clinical presentation and GP60 subgenotype lineages from aged formalin-fixed stool samples. Annals of Tropical Medicine and Parasitology 105, 339349.
De Waele, V., Van den Broeck, F., Huyse, T., McGrath, G., Higgins, I., Speybroeck, N., Berzano, M., Raleigh, P., Mulcahy, G. M. and Murphy, T. M. (2013). Panmictic structure of the Cryptosporidium parvum population in Irish calves: influence of prevalence and host movement. Applied and Environmental Microbiology 79, 25342541.
Diaz, P., Quilez, J., Chalmers, R. M., Panadero, R., Lopez, C., Sanchez-Acedo, C., Morrondo, P. and Diez-Banos, P. (2010 a). Genotype and subtype analysis of Cryptosporidium isolates from calves and lambs in Galicia (NW Spain). Parasitology 137, 11871193.
Diaz, P., Quilez, J., Robinson, G., Chalmers, R. M., Diez-Banos, P. and Morrondo, P. (2010 b). Identification of Cryptosporidium xiaoi in diarrhoeic goat kids (Capra hircus) in Spain. Veterinary Parasitology 172, 132134.
Diaz, P., Hadfield, S. J., Quilez, J., Soilan, M., Lopez, C., Panadero, R., Diez-Banos, P., Morrondo, P. and Chalmers, R. M. (2012). Assessment of three methods for multilocus fragment typing of Cryptosporidium parvum from domestic ruminants in north west Spain. Veterinary Parasitology 186, 188195.
Dillingham, R. A., Lima, A. A. and Guerrant, R. L. (2002). Cryptosporidiosis: epidemiology and impact. Microbes and Infection 4, 10591066.
Drumo, R., Widmer, G., Morrison, L. J., Tait, A., Grelloni, V., D'Avino, N., Pozio, E. and Caccio, S. M. (2012). Evidence of host-associated populations of Cryptosporidium parvum in Italy. Applied and Environmental Microbiology 78, 35233529.
Duszynski, D. W. (1969). Two new coccidia (Protozoa: Eimeriidae) from Costa Rican lizards with a review of the Eimeria from lizards. Journal of Protozoology 16, 581585.
Elwin, K., Hadfield, S. J., Robinson, G. and Chalmers, R. M. (2012 a). The epidemiology of sporadic human infections with unusual cryptosporidia detected during routine typing in England and Wales, 2000–2008. Epidemiology and Infection 140, 673683.
Elwin, K., Hadfield, S. J., Robinson, G., Crouch, N. D. and Chalmers, R. M. (2012 b). Cryptosporidium viatorum n. sp. (Apicomplexa: Cryptosporidiidae) among travellers returning to Great Britain from the Indian subcontinent, 2007–2011. International Journal of Parasitology 42, 675682.
Farzan, A., Parrington, L., Coklin, T., Cook, A., Pintar, K., Pollari, F., Friendship, R., Farber, J. and Dixon, B. (2011). Detection and characterization of Giardia duodenalis and Cryptosporidium spp. on swine farms in Ontario, Canada. Foodborne Pathogens and Disease 8, 12071213.
Fayer, R. and Santín, M. (2009). Cryptosporidium xiaoi n. sp. (Apicomplexa: Cryptosporidiidae) in sheep (Ovis aries). Veterinary Parasitology 164, 192200.
Fayer, R., Speer, C. A. and Dubey, J. P. (1997). The general biology of Cryptosporidium . In Cryptosporidium and Cryptosporidiosis (ed. Fayer, R.), pp. 141. Taylor & Francis, Boca Raton, FL, USA.
Fayer, R., Trout, J. M., Xiao, L., Morgan, U. M., Lal, A. A. and Dubey, J. P. (2001). Cryptosporidium canis n. sp. from domestic dogs. Journal of Parasitology 87, 14151422.
Fayer, R., Santin, M. and Xiao, L. (2005). Cryptosporidium bovis n. sp. (Apicomplex: Cryptosporidiidae) in cattle (Bos taurus). Journal of Parasitology 91, 624629.
Fayer, R., Santin, M. and Trout, J. M. (2008). Cryptosporidium ryanae n. sp. (Apicomplex: Cryptosporidiidae) in cattle (Bos taurus). Veterinary Parasitology 156, 191–190.
Fayer, R., Santin, M. and Macarisin, D. (2010). Cryptosporidium ubiquitum n. sp. in animals and humans. Veterinary Parasitology 172, 2332.
Feng, Y. (2010). Cryptosporidium in wild placental mammals. Experimental Parasitology 124, 128137.
Feng, Y., Ortega, Y., He, G., Das, P., Xu, M., Zhang, X., Fayer, R., Gatei, W., Cama, V. and Xiao, L. (2007). Wide geographic distribution of Cryptosporidium bovis and the deer-like genotype in bovines. Veterinary Parasitology 144, 19.
Feng, Y., Dearen, T., Cama, V. and Xiao, L. (2009). 90-kilodalton heat shock protein (hsp90) as a target for genotyping Cryptosporidium spp. known to infect humans. Eukaryotic Cell 8, 478482.
Feng, Y., Lal, A. A., Li, N. and Xiao, L. (2011 a). Subtypes of Cryptosporidium spp. in mice and other small mammals. Experimental Parasitology 127, 238242.
Feng, Y., Yang, W., Ryan, U., Zhang, L., Kvac, M., Koudela, B., Modry, D., Li, N., Fayer, R. and Xiao, L. (2011 b). Development of a multilocus sequence tool for typing Cryptosporidium muris and Cryptosporidium andersoni . Journal of Clinical Microbiology 49, 3441.
Feng, Y., Zhao, X., Chen, J., Jin, W., Zhou, X., Li, N., Wang, L. and Xiao, L. (2011 c). Occurrence, source, and human infection potential of Cryptosporidium and Giardia spp. in source and tap water in Shanghai, China. Applied and Environmental Microbiology 77, 36093616.
Feng, Y., Wang, L., Duan, L., Gomez-Puerta, L. A., Zhang, L., Zhao, X., Hu, J., Zhang, N. and Xiao, L. (2012). Extended outbreak of cryptosporidiosis in a pediatric hospital, China. Emerging Infectious Diseases 18, 312314.
Feng, Y., Torres, E., Li, N., Wang, L., Bowman, D. and Xiao, L. (2013). Population genetic characterisation of dominant Cryptosporidium parvum subtype IIaA15G2R1. International Journal of Parasitology 43, 11411147.
Feng, Y., Tiao, N., Li, N., Hlavsa, M. and Xiao, L. (2014). Multilocus sequence typing of an emerging Cryptosporidium hominis subtype in the United States. Journal of Clinical Microbiology 52, 524530.
Fiuza, V. R., Cosendey, R. I., Frazão-Teixeira, E., Santín, M., Fayer, R. and de Oliveira, F. C. (2011 a). Molecular characterization of Cryptosporidium in Brazilian sheep. Veterinary Parasitology 175, 360362.
Fiuza, V. R., Gallo, S. S., Frazão-Teixeira, E., Santín, M., Fayer, R. and Oliveira, F. C. (2011 b). Cryptosporidium pig genotype II diagnosed in pigs from the state of Rio de Janeiro, Brazil. Journal of Parasitology 97, 146147.
Foo, C., Farrell, J., Boxell, A., Robertson, I. and Ryan, U. M. (2007). Novel Cryptosporidium genotype in wild Australian mice (Mus domesticus). Applied and Environmental Microbiology 73, 76937696.
García-Presedo, I., Pedraza-Díaz, S., González-Warleta, M., Mezo, M., Gómez-Bautista, M., Ortega-Mora, L. M. and Castro-Hermida, J. A. (2013 a). Presence of Cryptosporidium scrofarum, C. suis and C. parvum subtypes IIaA16G2R1 and IIaA13G1R1 in Eurasian wild boars (Sus scrofa). Veterinary Parasitology 196, 497502.
García-Presedo, I., Pedraza-Díaz, S., González-Warleta, M., Mezo, M., Gómez-Bautista, M., Ortega-Mora, L. M. and Castro-Hermida, J. A. (2013 b). The first report of Cryptosporidium bovis, C. ryanae and Giardia duodenalis sub-assemblage A-II in roe deer (Capreolus capreolus) in Spain. Veterinary Parasitology 197, 658664.
Gatei, W., Wamae, C. N., Mbae, C., Waruru, A., Mulinge, E., Waithera, T., Gatika, S. M., Kamwati, S. K., Revathi, G. and Hart, C. A. (2006). Cryptosporidiosis: prevalence, genotype analysis, and symptoms associated with infections in children in Kenya. American Journal of Tropical Medicine and Hygiene 75, 7882.
Gatei, W., Das, P., Dutta, P., Sen, A., Cama, V., Lal, A. A. and Xiao, L. (2007). Multilocus sequence typing and genetic structure of Cryptosporidium hominis from children in Kolkata, India. Infection, Genetics and Evolution 7, 197205.
Geurden, T., Thomas, P., Casaert, S., Vercruysse, J. and Claerebout, E. (2008). Prevalence and molecular characterisation of Cryptosporidium and Giardia in lambs and goat kids in Belgium. Veterinary Parasitology 155, 142145.
Giles, M., Chalmers, R., Pritchard, G., Elwin, K., Mueller-Doblies, D. and Clifton-Hadley, F. (2009). Cryptosporidium hominis in a goat and a sheep in the UK. Veterinary Record 164, 2425.
Goh, S., Reacher, M., Casemore, D. P., Verlander, N. Q., Chalmers, R., Knowles, M., Williams, J., Osborn, K. and Richards, S. (2004). Sporadic cryptosporidiosis, North Cumbria, England, 1996–2000. Emerging Infectious Diseases 10, 10071015.
Goma, F. Y., Geurden, T., Siwila, J., Phiri, I. G. K., Claerebout, E. and Vercruysse, J. (2007). The prevalence and molecular characterisation of Cryptosporidium spp. in small ruminants in Zambia. Small Ruminant Research 72, 7780.
Grinberg, A., Biggs, P. J., Dukkipati, V. S. and George, T. T. (2013). Extensive intra-host genetic diversity uncovered in Cryptosporidium parvum using next generation sequencing. Infection Genetics and Evolution 15, 1824.
Hadfield, S. J., Robinson, G., Elwin, K. and Chalmers, R. M. (2011). Detection and differentiation of Cryptosporidium spp. in human clinical samples using real-time PCR. Journal of Clinical Microbiology 49, 918924.
Helmy, Y. A., Krücken, J., Nöckler, K., von Samson-Himmelstjerna, G. and Zessin, K. H. (2013). Molecular epidemiology of Cryptosporidium in livestock animals and humans in the Ismailia province of Egypt. Veterinary Parasitology 193, 1524.
Herges, G. R., Widmer, G., Clark, M. E., Khan, E., Giddings, C. W., Brewer, M. and McEvoy, J. M. (2012). Evidence that Cryptosporidium parvum populations are panmictic and unstructured in the upper midwest of the United States. Applied and Environmental Microbiology 78, 80968101.
Hoover, D. M., Hoerr, F. J., Carlton, W. W., Hinsman, E. J. and Ferguson, H. W. (1981). Enteric cryptosporidiosis in a naso tang, Naso lituratus Block and Schneider. Journal of Fish Disease 4, 425428.
Hunter, P. R., Hughes, S., Woodhouse, S., Syed, Q., Verlander, N. Q., Chalmers, R. M., Morgan, K., Nichols, G., Beeching, N. and Osborn, K. (2004). Sporadic cryptosporidiosis case-control study with genotyping. Emerging Infectious Disease 10, 12411249.
Imre, K., Lobo, L. M., Matos, O., Popescu, C., Genchi, C. and Dărăbuş, G. (2011). Molecular characterisation of Cryptosporidium isolates from pre-weaned calves in Romania: is there an actual risk of zoonotic infections? Veterinary Parasitology 181, 321324.
Inman, L. R. and Takeuchi, A. (1979). Spontaneous cryptosporidiosis in an adult female rabbit. Veterinary Pathology 16, 8995.
Insulander, M., Silverlas, C., Lebbad, M., Karlsson, L., Mattsson, J. G. and Svenungsson, B. (2013). Molecular epidemiology and clinical manifestations of human cryptosporidiosis in Sweden. Epidemiology and Infection 141, 10091020.
Intergovernmental Panel on Climate Change (IPCC). (2013). Fifth Assessment Report. http://www.ipcc.ch/report/ar5/wg1/.
Iseki, M. (1979). Cryptosporidium felis sp. n. (Protozoa: Eimeriorina) from the domestic cat. Japanese Journal of Parasitology 28, 285307.
Jeníková, M., Němejc, K., Sak, B., Květoňová, D. and Kváč, M. (2010). New view on the age-specificity of pig Cryptosporidium by species-specific primers for distinguishing Cryptosporidium suis and Cryptosporidium pig genotype II. Veterinary Parasitology 176, 120125.
Jenkins, M. B., Liotta, J. L., Lucio-Forster, A. and Bowman, D. D. (2010). Concentrations, viability, and distribution of Cryptosporidium genotypes in lagoons of swine facilities in the Southern Piedmont and in coastal plain watersheds of Georgia. Applied and Environmental Microbiology, 76, 57575763.
Jirku, M., Valigurova, A., Koudela, B., Krzek, J., Modry, D. and Slapeta, J. (2008). New species of Cryptosporidium Tyzzer, 1907 (Apicomplexa) from amphibian host: morphology, biology, and phylogeny. Folia Parasitologica 55, 8194.
Johnson, J., Buddle, R., Reid, S., Armson, A. and Ryan, U. M. (2008). Prevalence of Cryptosporidium genotypes in pre and post-weaned pigs in Australia. Experimental Parasitology 119, 418421.
Jothikumar, N., da Silva, A. J., Moura, I., Qvarnstrom, Y. and Hill, V. R. (2008). Detection and differentiation of Cryptosporidium hominis and Cryptosporidium parvum by dual TaqMan assays. Journal of Medical Microbiology 57, 10991105.
Khan, S. M., Debnath, C., Pramanik, A. K., Xiao, L., Nozaki, T. and Ganguly, S. (2010). Molecular characterization and assessment of zoonotic transmission of Cryptosporidium from dairy cattle in West Bengal, India. Veterinary Parasitology 171, 4147.
Koinari, M., Karl, S., Ng-Hublin, J., Lymbery, A. J. and Ryan, U. M. (2013). Identification of novel and zoonotic Cryptosporidium species in fish from Papua New Guinea. Veterinary Parasitology 198, 19.
Koinari, M., Lymbery, A. J. and Ryan, U. M. (2014). Cryptosporidium species in sheep and goats from Papua New Guinea. Experimental Parasitology 41, 134137.
Kotloff, K. L., Nataro, J. P., Blackwelder, W. C., Nasrin, D., Farag, T. H., Panchalingam, S., Wu, Y., Sow, S. O., Sur, D., Breiman, R. F., Faruque, A. S., Zaidi, A. K., Saha, D., Alonso, P. L., Tamboura, B., Sanogo, D., Onwuchekwa, U., Manna, B., Ramamurthy, T., Kanungo, S., Ochieng, J. B., Omore, R., Oundo, J. O., Hossain, A., Das, S. K., Ahmed, S., Qureshi, S., Quadri, F., Adegbola, R. A., Antonio, M., Hossain, M. J., Akinsola, A., Mandomando, I., Nhampossa, T., Acacio, S., Biswas, K., O'Reilly, C. E., Mintz, E. D., Berkeley, L. Y., Muhsen, K., Sommerfelt, H., Robins-Browne, R. M. and Levine, M. M. (2013). Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study. Lancet 382, 209222.
Koudela, B. and Modry, D. (1998). New species of Cryptosporidium (Apicomplexa, Cryptosporidiidae) from lizards. Folia Parasitologia 45, 93100.
Kváč, M., Hanzlíková, D., Sak, B. and Kvetonová, D. (2009 a). Prevalence and age-related infection of Cryptosporidium suis, C. muris and Cryptosporidium pig genotype II in pigs on a farm complex in the Czech Republic. Veterinary Parasitology 160, 319322.
Kváč, M., Kvetonová, D., Sak, B. and Ditrich, O. (2009 b). Cryptosporidium pig genotype II in immunocompetent man. Emerging Infectious Diseases 15, 982983.
Kváč, M., Sakova, K., Kvetonova, D., Kicia, M., Wesolowska, M., McEvoy, J. and Sak, B. (2013 a). Gastroenteritis caused by the Cryptosporidium hedgehog genotype in an immunocompetent man. Journal of Clinical Microbiology 52, 347349.
Kváč, M., Kestřánová, M., Pinková, M., Květoňová, D., Kalinová, J., Wagnerová, P., Kotková, M., Vítovec, J., Ditrich, O., McEvoy, J., Stenger, B. and Sak, B. (2013 b). Cryptosporidium scrofarum n. sp. (Apicomplexa: Cryptosporidiidae) in domestic pigs (Sus scrofa). Veterinary Parasitology 191, 218227.
Kváč, M., McEvoy, J., Loudová, M., Stenger, B., Sak, B., Květoňová, D., Ditrich, O., Rašková, V., Moriarty, E., Rost, M., Macholán, M. and Piálek, J. (2013 c). Coevolution of Cryptosporidium tyzzeri and the house mouse (Mus musculus). International Journal for Parasitology 43, 805817.
Kváč, M., Saková, K., Kvĕtoňová, D., Kicia, M., Wesołowska, M., McEvoy, J. and Sak, B. (2014 a). Gastroenteritis caused by the Cryptosporidium hedgehog genotype in an immunocompetent man. Journal of Clinical Microbiology 52, 347349.
Kváč, M., Hofmannová, L., Hlásková, L., Květoňová, D., Vítovec, J., McEvoy, J. and Sak, B. (2014 b). Cryptosporidium erinacei n. sp. (Apicomplexa: Cryptosporidiidae) in hedgehogs. Veterinary Parasitology 201, 917.
Lalonde, L. F., Reyes, J. and Gajadhar, A. A. (2013). Application of a qPCR assay with melting curve analysis for detection and differentiation of protozoan oocysts in human fecal samples from Dominican Republic. American Journal of Tropical Medicine and Hygiene 89, 892898.
Learmonth, J. J., Ionas, G., Ebbett, K. A. and Kwan, E. S. (2004). Genetic characterization and transmission cycles of cryptosporidium species isolated from humans in New Zealand. Applied and Environmental Microbiology 70, 39733978.
Leoni, F., Amar, C., Nichols, G., Pedraza-Díaz, S. and McLauchlin, J. (2006). Genetic analysis of Cryptosporidium from 2414 humans with diarrhoea in England between 1985 and 2000. Journal of Medical Microbiology 55, 703707.
Levine, N. D. (1980). Some corrections of coccidian (Apicomplexa: Protozoa) nomenclature. Journal of Parasitology 66, 830834.
Li, N., Xiao, L., Cama, V. A., Ortega, Y., Gilman, R. H., Guo, M. and Feng, Y. (2013). Genetic recombination and Cryptosporidium hominis virulent subtype IbA10G2. Emerging Infectious Diseases 19, 15731582.
Li, N., Xiao, L., Alderisio, K., Elwin, K., Cebelinski, E., Chalmers, R., Santin, M., Fayer, R., Kvac, M., Ryan, U., Sak, B., Stanko, M., Guo, Y., Wang, L., Zhang, L., Cai, J., Roellig, D. and Feng, Y. (2014). Subtyping Cryptosporidium ubiquitum, a zoonotic pathogen emerging in humans. Emerging Infectious Diseases 20, 217224.
Lindsay, D. S., Upton, S. J., Owens, D. S., Morgan, U. M., Mead, J. R. and Blagburn, B. L. (2000). Cryptosporidium andersoni n. sp. (Apicomplexa: Cryptosporidiidae) from cattle, Bos taurus . Journal of Eukaryotic Microbiology 47, 91–85.
Liu, L., Johnson, H. L., Cousens, S., Perin, J., Scott, S., Lawn, J. E., Rudan, I., Campbell, H., Cibulskis, R., Li, M., Mathers, C. and Black, R. E. (2012). Global, regional, and national causes of child mortality: an updated systematic analysis for 2010 with time trends since 2000. Lancet 379, 21512161.
Liu, H., Shen, Y., Yin, J., Yuan, Z., Jiang, Y., Xu, Y., Pan, W., Hu, Y. and Cao, J. (2014). Prevalence and genetic characterization of Cryptosporidium, Enterocytozoon, Giardia and Cyclospora in diarrheal outpatients in China. BMC Infectious Diseases 14, 25.
Llorente, M. T., Clavel, A., Goni, M. P., Varea, M., Seral, C., Becerril, R., Suarez, L. and Gomez-Lus, R. (2007). Genetic characterization of Cryptosporidium species from humans in Spain. Parasitology International 51, 201205.
Lucio-Forster, A., Griffiths, J. K., Cama, V. A., Xiao, L. and Bowman, D. D. (2010). Minimal zoonotic risk of cryptosporidiosis from pet dogs and cats. Trends in Parasitology 26, 174179.
Lv, C., Zhang, L., Wang, R., Jian, F., Zhang, S., Ning, C., Wang, H., Feng, C., Wang, X., Ren, X., Qi, M. and Xiao, L. (2009). Cryptosporidium spp. in wild, laboratory, and pet rodents in China: prevalence and molecular characterization. Applied and Environmental Microbiology 75, 76927699.
Mallon, M., MacLeod, A., Wastling, J., Smith, H., Reilly, B. and Tait, A. (2003). Population structures and the role of genetic exchange in the zoonotic pathogen Cryptosporidium parvum . Journal of Molecular Evolution 56, 407417.
Mary, C., Chapey, E., Dutoit, E., Guyot, K., Hasseine, L., Jeddi, F., Menotti, J., Paraud, C., Pomares, C., Rabodonirina, M., Rieux, A. and Derouin, F. (2013). Multicentric evaluation of a new real-time PCR assay for quantification of Cryptosporidium sp and identification of Cryptosporidium parvum and hominis . Journal of Clinical Microbiology 51, 25562563.
Matschoulsky, S. N. (1947). Coccidia of wild birds of Buryatia: second communication. Trudy Buryat-Mongolskogo Zooveterinarnogo Instituta (Ulan-Ude) 3, 93101 (in Russian).
McDonald, V. (2011). Cryptosporidiosis: host immune responses and the prospects for effective immunotherapies. Expert Reviews on Antibodies, Infection and Therapy 9, 10771086.
Meireles, M., de Oliveira, F., Teixeira, W., Coelho, W. and Mendes, L. (2011). Molecular characterization of Cryptosporidium spp. in dairy calves from the state of Sao Paulo, Brazil. Parasitology Research 109, 949951.
Molloy, S. F., Smith, H. V., Kirwan, P., Nichols, R. A., Asaolu, S. O., Connelly, L. and Holland, C. V. (2010). Identification of a high diversity of Cryptosporidium species genotypes and subtypes in a pediatric population in Nigeria. American Journal of Tropical Medicine and Hygiene 82, 608613.
Morgan, U. M., Buddle, R., Armson, A. and Thompson, R. C. A. (1999 a). Molecular and biological characterisation of Cryptosporidium in pigs. Australian Veterinary Journal 77, 4447.
Morgan, U. M., Sturdee, A. P., Singleton, G., Gomez, M. S., Gracenea, M., Torres, J., Hamilton, S. G., Woodside, D. P. and Thompson, R. C. (1999 b). The Cryptosporidium ‘mouse’ genotype is conserved across geographic areas. Journal of Clinical Microbiology 37, 13021305.
Morgan-Ryan, U. M., Fall, A., Ward, L. A., Hijjawi, N., Sulaiman, I., Fayer, R., Thompson, R. C. A., Olson, M., Lal, A. A. and Xiao, L. (2002). Cryptosporidium hominis n. sp. (Apicompolexa: Cryptosporidiidae) from Homo sapiens . Journal of Eukaryotic Microbiology 49, 433440.
Morse, T. D., Nichols, R. A., Grimason, A. M., Campbell, B. M., Tembo, K. C. and Smith, H. V. (2007). Incidence of cryptosporidiosis species in paediatric patients in Malawi. Epidemiology and Infection 135, 13071315.
Mosier, D. A. and Oberst, R. D. (2000). Cryptosporidiosis. A global challenge. Annals of the New York Academy of Science 916, 102111.
Muhid, A., Robertson, I., Ng, J. and Ryan, U. (2011). Prevalence of and management factors contributing to Cryptosporidium sp. infection in pre-weaned and post-weaned calves in Johor, Malaysia. Experimental Parasitology 127, 534538.
Muthusamy, D., Rao, S. S., Ramani, S., Monica, B., Banerjee, I., Abraham, O. C., Mathai, D. C., Primrose, B., Muliyil, J., Wanke, C. A., Ward, H. D. and Kang, G. (2006). Multilocus genotyping of Cryptosporidium sp. isolates from human immunodeficiency virus-infected individuals in South India. Journal of Clinical Microbiology 44, 632634.
Nazemalhosseini-Mojarad, E., Feng, Y. and Xiao, L. (2012). The importance of subtype analysis of Cryptosporidium spp. in epidemiological investigations of human cryptosporidiosis in Iran and other Mideast countries. Gastroenterology and Hepatology from Bed to Bench 5, 6770.
Němejc, K., Sak, B., Květoňová, D., Hanzal, V., Jeníková, M. and Kváč, M. (2012). The first report on Cryptosporidium suis and Cryptosporidium pig genotype II in Eurasian wild boars (Sus scrofa) (Czech Republic). Veterinary Parasitology 184, 122125.
Němejc, K., Sak, B., Květoňová, D., Kernerová, N., Rost, M., Cama, V. A. and Kváč, M. (2013). Occurrence of Cryptosporidium suis and Cryptosporidium scrofarum on commercial swine farms in the Czech Republic and its associations with age and husbandry practices. Parasitology Research 112, 11431154.
Ng, J., Yang, R., Whiffin, V., Cox, P. and Ryan, U. (2011). Identification of zoonotic Cryptosporidium and Giardia genotypes infecting animals in Sydney's water catchments. Experimental Parasitology 128, 138144.
Ng, J. S., Eastwood, K., Walker, B., Durrheim, D. N., Massey, P. D., Porigneaux, P., Kemp, R., McKinnon, B., Laurie, K., Miller, D., Bramley, E. and Ryan, U. (2012). Evidence of Cryptosporidium transmission between cattle and humans in northern New South Wales. Experimental Parasitology 130, 437441.
Nolan, M. J., Jex, A. R., Koehler, A. V., Haydon, S. R., Stevens, M. A., Gasser, R. B. (2013). Molecular-based investigation of Cryptosporidium and Giardia from animals in water catchments in southeastern Australia. Water Research 47, 17261740.
O'Connor, R. M., Wanyiri, J. W., Cevallos, A. M., Priest, J. W. and Ward, H. D. (2007). Cryptosporidium parvum glycoprotein gp40 localizes to the sporozoite surface by association with gp15. Molecular and Biochemical Parasitology 156, 8083.
Ogassawara, S., Benassi, S., Larsson, C. E. and Hagiwara, M. K. (1986). Cryptosporidium curyi sp. n., in the feces of cats in the city of Sao Paulo, Brazil. Revista de Microbiologia 17, 346349.
Okhuysen, P. C., Chappell, C. L., Crabb, J. H., Sterling, C. R. and DuPont, H. L. (1999). Virulence of three distinct Cryptosporidium parvum isolates for healthy adults. Journal of Infectious Diseases 180, 12751281.
Palenzuela, O., Alvarez-Pellitero, P. and Sitjà-Bobadilla, A. (2010). Molecular characterization of Cryptosporidium molnari reveals a distinct piscine clade. Applied and Environmental Microbiology 76, 76467649.
Palmer, C. S., Traub, R. J., Robertson, I. D., Devlin, G., Rees, R. and Thompson, R. C. (2008). Determining the zoonotic significance of Giardia and Cryptosporidium in Australian dogs and cats. Veterinary Parasitology 154, 142147.
Paperna, I. and Vilenkin, M. (1996). Cryptosporidiosis in the gourami Trichogaster leeri: description of a new species and a proposal for a new genus, Piscicryptosporidium, for species infecting fish. Diseases of Aquatic Organisms 27, 95101.
Paperna, I., Landsberg, J. H. and Ostrovska, K. (1986). Cryptosporidia of lower vertebrates. Society of Protozoology, Abstract No. 145.
Park, J. H., Guk, S. M., Han, E. T., Shin, E. H., Kim, J. L. and Chai, J. Y. (2006). Genotype analysis of Cryptosporidium spp. prevalent in a rural village in Hwasun-gun, Republic of Korea. Korean Journal of Parasitology 44, 2733.
Pavlásek, I. (1999). Cryptosporidia: biology, diagnosis, host spectrum, specificity, and the environment. Remedia Klinicka Mikrobiologie 3, 290301.
Pavlasek, I. and Ryan, U. (2008). Cryptosporidium varanii takes precedence over C. saurophilum . Experimental Parasitology 118, 434437.
Pavlásek, I., Lávicková, M., Horák, P., Král, J. and Král, B. (1995). Cryptosporidium varanii n. sp. (Apicomplexa: Cryptosporidiidae) in Emerald monitor (Varanus prasinus Schlegal, 1893) in captivity in Prague zoo. Gazella 22, 99108.
Payne, P., Lancaster, L. A., Heinzman, M. and McCutchan, J. A. (1983). Identification of Cryptosporidium in patients with acquired immunodeficiency syndrome. New England Journal of Medicine 309, 613614.
Power, M. L. (2010). Biology of Cryptosporidium from marsupial hosts. Experimental Parasitology 124, 4044.
Power, M. L. and Ryan, U. M. (2008). A new species of Cryptosporidium (Apicomplexa: Cryptosporidiidae) from eastern grey kangaroos (Macropus giganteus). Journal of Parasitology 94, 11141117.
Power, M. L., Cheung-Kwok-Sang, C., Slade, M. and Williamson, S. (2009). Cryptosporidium fayeri: diversity within the GP60 locus of isolates from different marsupial hosts. Experimental Parasitology 121, 219223.
Proctor, S. J. and Kemp, R. L. (1974). Cryptosporidium anserinum sp. n. (Sporozoa) in a domestic goose Anser anser L., from Iowa. Journal of Protozoology 21, 664666.
Quílez, J., Torres, E., Chalmers, R. M., Hadfield, S. J., Del Cacho, E. and Sánchez-Acedo, C. (2008). Cryptosporidium genotypes and subtypes in lambs and goat kids in Spain. Applied and Environmental Microbiology 74, 60266031.
Quilez, J., Vergara-Castiblanco, C., Monteagudo, L., Del Cacho, E. and Sanchez-Acedo, C. (2011). Multilocus fragment typing and genetic structure of Cryptosporidium parvum isolates from diarrheic preweaned calves in Spain. Applied and Environmental Microbiology 77, 77797786.
Quilez, J., Vergara-Castiblanco, C., Monteagudo, L., Del Cacho, E. and Sanchez-Acedo, C. (2013). Host-association of C. parvum populations infecting domestic ruminants in Spain. Applied and Environmental Microbiology 79, 53635371.
Raskova, V., Kvetonova, D., Sak, B., McEvoy, J., Edwinson, A., Stenger, B. and Kvac, M. (2013). Human cryptosporidiosis caused by Cryptosporidium tyzzeri and C. parvum isolates presumably transmitted from wild mice. Journal of Clinical Microbiology 51, 360362.
Ren, X., Zhao, J., Zhang, L., Ning, C., Jian, F., Wang, R., Lv, C., Wang, Q., Arrowood, M. J. and Xiao, L. (2012). Cryptosporidium tyzzeri n. sp. (Apicomplexa: Cryptosporidiidae) in domestic mice (Mus musculus). Experimental Parasitology 130, 274281.
Rengifo-Herrera, C., Ortega-Mora, L. M., Gómez-Bautista, M., García-Moreno, F. T., García-Párraga, D., Castro-Urda, J. and Pedraza-Díaz, S. (2011). Detection and characterization of a Cryptosporidium isolate from a southern elephant seal (Mirounga leonina) from the Antarctic peninsula. Applied and Environmental Microbiology 77, 15241527.
Rengifo-Herrera, C., Ortega-Mora, L. M., Gómez-Bautista, M., García-Peña, F. J., García-Párraga, D. and Pedraza-Díaz, S. (2013). Detection of a novel genotype of Cryptosporidium in Antarctic pinnipeds. Veterinary Parasitology 191, 112118.
Robertson, L. J. (2009). Giardia and Cryptosporidium infections in sheep and goats: a review of the potential for transmission to humans via environmental contamination. Epidemiology and Infection 137, 913921.
Robertson, L. J. and Fayer, R. (2013). Cryptosporidium . In Foodborne Protozoan Parasites (ed. Robertson, L. J. and Smith, H. V.), pp. 3364. Nova Science Publishers, Hauppauge, NY, USA.
Robertson, B., Sinclair, M. I., Forbes, A. B., Veitch, M., Cunliffe, D., Willis, J. and Fairley, C. K. (2002). Case-control studies of sporadic cryptosporidiosis in Melbourne and Adelaide, Australia. Epidemiology and Infection 128, 419431.
Robinson, G. and Chalmers, R. M. (2012). Assessment of polymorphic genetic markers for multi-locus typing of Cryptosporidium parvum and Cryptosporidium hominis . Experimental Parasitology 132, 200215.
Robinson, G., Wright, S., Elwin, K., Hadfield, S. J., Katzer, F., Bartley, P. M., Hunter, P. R., Nath, M., Innes, E. A. and Chalmers, R. M. (2010). Re-description of Cryptosporidium cuniculus Inman and Takeuchi, 1979 (Apicomplexa: Cryptosporidiidae): morphology, biology and phylogeny. International Journal for Parasitology 40, 15391548.
Roy, S. L., DeLong, S. M., Stenzel, S. A., Shiferaw, B., Roberts, J. M., Khalakdina, A., Marcus, R., Segler, S. D., Shah, D., Thomas, S., Vugia, D. J., Zansky, S. M., Dietz, V., and Beach, M. J. (2004). Risk factors for sporadic cryptosporidiosis among immunocompetent persons in the United States from 1999 to 2001. Journal of Clinical Microbiology 42, 29442951.
Ruecker, N. J., Matsune, J. C., Wilkes, G., Lapen, D. R., Topp, E., Edge, T. A., Sensen, C. W., Xiao, L. and Neumann, N. F. (2012). Molecular and phylogenetic approaches for assessing sources of Cryptosporidium contamination in water. Water Research 46, 51355150.
Ruecker, N. J., Matsune, J. C., Lapen, D. R., Topp, E., Edge, T. A. and Neumann, N. F. (2013). The detection of Cryptosporidium and the resolution of mixtures of species and genotypes from water. Infection Genetics and Evolution 15, 39.
Ryan, U. (2010). Cryptosporidium in birds, fish and amphibians. Experimental Parasitology 124, 113120.
Ryan, U. and Power, M. (2012). Cryptosporidium species in Australian wildlife and domestic animals. Parasitology 139, 16731688.
Ryan, U. M. and Xiao, L. (2014). Taxonomy and Molecular Taxonomy. In Cryptosporidium: Parasite and Disease (ed. Cacciò, S. M. and Widmer, G.). Springer, New York, NY, USA. In press.
Ryan, U. M., Samarasinghe, B., Read, C., Buddle, J. R., Robertson, I. D. and Thompson, R. C. (2003 a). Identification of a novel Cryptosporidium genotype in pigs. Applied and Environmental Microbiology 69, 39703974.
Ryan, U. M., Xiao, L., Read, C., Zhou, L., Lal, A. A. and Pavlasek, I. (2003 b). Identification of novel Cryptosporidium genotypes from the Czech Republic. Applied and Environmental Microbiology 69, 43024307.
Ryan, U. M., Xiao, L., Read, C., Sulaiman, I., Monis, P., Lal, A. A., Fayer, R. and Pavlasek, I. (2003 c). A redescription of Cryptosporidium galli Pavlasek, 1999 (Apicomplexa: Cryptosporidiidae) from birds. Journal of Parasitology 89, 809813.
Ryan, U. M., Monis, P., Enemark, H. L., Sulaiman, I., Samarasinge, B., Read, C., Buddle, R., Robertson, I., Zhou, L., Thompson, R. C. A. and Xiao, L. (2004). Cryptosporidium suis n. sp. (Apicomplexa: Cryptosporidiidae) in pigs (Sus scrofa). Journal of Parasitology 90, 769773.
Ryan, U. M., Bath, C., Robertson, I., Read, C., Elliot, A., McInnes, L., Traub, R. and Besier, B. (2005). Sheep may not be an important zoonotic reservoir for Cryptosporidium and Giardia parasites. Applied and Environmental Microbiology 71, 49924997.
Ryan, U. M., Power, M. and Xiao, L. (2008). Cryptosporidium fayeri n. sp. (Apicomplexa: Cryptosporidiidae) from the red kangaroo (Macropus rufus). Journal of Eukaryotic Microbiology 55, 2226.
Santín, M. (2013). Clinical and subclinical infections with Cryptosporidium in animals. New Zealand Veterinary Journal 61, 110.
Santín, M., Dixon, B. R. and Fayer, R. (2005). Genetic characterization of Cryptosporidium isolates from ringed seals (Phoca hispida) in Northern Quebec, Canada. Journal of Parasitology 91, 712716.
Santín, M., Trout, J. M. and Fayer, R. (2007). Prevalence and molecular characterization of Cryptosporidium and Giardia species and genotypes in sheep in Maryland. Veterinary Parasitology 146, 1724.
Scallan, E., Hoekstra, R. M., Angulo, F. J., Tauxe, R. V. and Hoekstra, R. M. (2011). Foodborne illness acquired in the United States – major pathogens. Emerging Infectious Diseases 17, 715.
Sevá Ada, P., Funada, M. R., Souza Sde, O., Nava, A., Richtzenhain, L. J. and Soares, R. M. (2010). Occurrence and molecular characterization of Cryptosporidium spp. isolated from domestic animals in a rural area surrounding Atlantic dry forest fragments in Teodoro Sampaio municipality, State of São Paulo, Brazil. Revista Brasileira de Parasitologia Veterinaria 19, 249253.
Silva, S. O., Richtzenhain, L. J., Barros, I. N., Gomes, A. M., Silva, A. V., Kozerski, N. D., de Araújo Ceranto, J. B., Keid, L. B. and Soares, R. M. (2013). A new set of primers directed to 18S rRNA gene for molecular identification of Cryptosporidium spp. and their performance in the detection and differentiation of oocysts shed by synanthropic rodents. Experimental Parasitology 135, 551557.
Silverlås, C. and Blanco-Penedo, I. (2013). Cryptosporidium spp. in calves and cows from organic and conventional dairy herds. Epidemiology and Infection 141, 529539.
Silverlås, C., de Verdier, K., Emanuelson, U., Mattsson, J. G. and Björkman, C. (2010). Cryptosporidium infection in herds with and without calf diarrhoeal problems. Parasitology Research 107, 14351444.
Silverlås, C., Mattsson, J. G., Insulander, M. and Lebbad, M. (2012). Zoonotic transmission of Cryptosporidium meleagridis on an organic Swedish farm. International Journal for Parasitology 42, 963967.
Slapeta, J. (2006). Cryptosporidium species found in cattle: a proposal for a new species. Trends in Parasitology 22, 469474.
Slapeta, J. (2013). Cryptosporidiosis and Cryptosporidium species in animals and humans: a thirty colour rainbow? International Journal for Parasitology 43, 957970.
Slavin, D. (1955). Cryptosporidium meleagridis (sp. nov.). Journal of Comparative Pathology 65, 262270.
Staggs, S. E., Beckman, E. M., Keely, S. P., Mackwan, R., Ware, M. W., Moyer, A. P., Ferretti, J. A., Sayed, A., Xiao, L. and Villegas, E. N. (2013). The applicability of TaqMan-based quantitative real-time PCR assays for detecting and enumerating spp. oocysts in the environment. PLOS ONE 8, e66562.
Striepen, B. (2013). Time to tackle cryptosporidiosis. Nature 503, 189191.
Sulaiman, I. M., Hira, P. R., Zhou, L., Al-Ali, F. M., Al-Shelahi, F. A., Shweiki, H. M., Iqbal, J., Khalid, N. and Xiao, L. (2005). Unique endemicity of cryptosporidiosis in children in Kuwait. Journal of Clinical Microbiology 43, 28052809.
Sweeny, J. P., Ryan, U. M., Robertson, I. D., Yang, R., Bell, K. and Jacobson, C. (2011). Longitudinal investigation of protozoan parasites in meat lamb farms in southern Western Australia. Preventive Veterinary Medicine 101, 192203.
Tanriverdi, S., Grinberg, A., Chalmers, R. M., Hunter, P. R., Petrovic, Z., Akiyoshi, D. E., London, E., Zhang, L., Tzipori, S., Tumwine, J. K. and Widmer, G. (2008). Inferences about the global population structure of Cryptosporidium parvum and Cryptosporidium hominis . Applied and Environmental Microbiology 74, 72277234.
Tosini, F., Drumo, R., Elwin, K., Chalmers, R. M., Pozio, E. and Caccio, S. M. (2010). The CpA135 gene as a marker to identify Cryptosporidium species infecting humans. Parasitology International 59, 606609.
Traversa, D. (2010). Evidence of a new species of Cryptosporidium infecting tortoises: Cryptosporidium ducimarci . Parasites and Vectors 3, 21.
Triffit, M. J. (1925). Observations on two new species of coccidia parasitic in snakes. Protozoology 1, 1926.
Tyzzer, E. E. (1907). A sporozoan found in the peptic glands of the common mouse. Proceedings of the Society for Experimental Biology and Medicine 5, 1213.
Tyzzer, E. E. (1910). An extracellular coccidium, Cryptosporidium muris (gen. et sp. nov) of the gastric glands of the common mouse. Journal of Medical Research 23, 487511.
Tyzzer, E. E. (1912). Cryptosporidium parvum (sp. nov.), a coccidium found in the small intestine of the common mouse. Archives fur Protistenkunde 26, 394412.
Upton, S. J. and Current, W. L. (1985). The species of Cryptosporidium (Apicomplexa: Cryptosporidiidae) infecting mammals. Journal of Parasitology 74, 625629.
Venu, R., Latha, B. R., Basith, S. A., Raj, G. D., Sreekumar, C. and Raman, M. (2012). Molecular prevalence of Cryptosporidium spp. in dairy calves in Southern states of India. Veterinary Parasitology 188, 1924.
Vetterling, J. M., Jervis, H. R., Merrill, T. G. and Sprinz, H. (1971). Cryptosporidium wrairi sp. n. from the guinea pig Cavia porcellus, with an amendation of the genus. Journal of Protozoology 18, 243247.
Waldron, L. S., Cheung-Kwok-Sang, C. and Power, M. L. (2010). Wildlife-associated Cryptosporidium fayeri in humans, Australia. Emerging Infectious Disease 16, 20062007.
Waldron, L. S., Dimeski, B., Beggs, P. J., Ferrari, B. C. and Power, M. L. (2011). Molecular epidemiology, spatiotemporal analysis, and ecology of sporadic human cryptosporidiosis in Australia. Applied and Environmental Microbiology 77, 77577765.
Walker, C. L., Rudan, I., Liu, L., Nair, H., Theodoratou, E., Bhutta, Z. A., O'Brien, K. L., Campbell, H. and Black, R. E. (2013). Childhood pneumonia and diarrhea 1. Global burden of childhood pneumonia and diarrhea. Lancet 381, 14051416.
Wang, Y., Feng, Y., Cui, B., Jian, F., Ning, C., Wang, R., Zhang, L. and Xiao, L. (2010 a). Cervine genotype is the major Cryptosporidium genotype in sheep in China. Parasitology Research 106, 341347.
Wang, R., Qiu, S., Jian, F., Zhang, S., Shen, Y., Zhang, L., Ning, C., Cao, J., Qi, M. and Xiao, L. (2010 b). Prevalence and molecular identification of Cryptosporidium spp. in pigs in Henan, China. Parasitology Research 107, 14891494.
Wang, R., Wang, H., Sun, Y., Zhang, L., Jian, F., Qi, M., Ning, C. and Xiao, L. (2011 a). Characteristics of Cryptosporidium transmission in preweaned dairy cattle in Henan, China. Journal of Clinical Microbiology 49, 10771082.
Wang, R., Jian, F., Zhang, L., Ning, C., Liu, A., Zhao, J., Feng, Y., Qi, M., Wang, H., Lv, C., Zhao, G. and Xiao, L. (2012). Multilocus sequence subtyping and genetic structure of Cryptosporidium muris and Cryptosporidium andersoni . PLOS ONE 7, e43782.
Wang, L., Zhang, H., Zhao, X., Zhang, L., Zhang, G., Guo, M., Liu, L., Feng, Y. and Xiao, L. (2013). Zoonotic Cryptosporidium species and Enterocytozoon bieneusi genotypes in HIV-positive patients on antiretroviral therapy. Journal of Clinical Microbiology 51, 557–63.
Wetzel, R. (1938). Ein neues Coccid (Cryptosporidium vulpis sp. nov.) aus dem Rotfuchs. [New coccidia (Cryptosporidium vulpis sp. nov.) from Red Fox.]. Archiv fur Wissenschaftliche und Praktische Tierheilkunde 74, 3940.
Widmer, G. and Lee, Y. (2010). Comparison of single- and multilocus genetic diversity in the protozoan parasites Cryptosporidium parvum and C. hominis . Applied and Environmental Microbiology 76, 66396644.
Widmer, G. and Sullivan, S. (2012). Genomics and population biology of Cryptosporidium species. Parasite Immunology 34, 6171.
Widmer, G., Lee, Y., Hunt, P., Martinelli, A., Tolkoff, M. and Bodi, K. (2012). Comparative genome analysis of two Cryptosporidium parvum isolates with different host range. Infection Genetics and Evolution, 12, 12131221.
Wielinga, P. R., de Vries, A., van der Goot, T. H., Mank, T., Mars, M. H., Kortbeek, L. M. and van der Giessen, J. W. (2008). Molecular epidemiology of Cryptosporidium in humans and cattle in the Netherlands. International Journal for Parasitology 38, 809817.
Xiao, L. (2010). Molecular epidemiology of cryptosporidiosis: an update. Experimental Parasitology 124, 8089.
Xiao, L. and Feng, Y. (2008). Zoonotic cryptosporidiosis. FEMS Immunology and Medical Microbiology 52, 309323.
Xiao, L., Morgan, U. M., Limor, J., Escalante, A., Arrowood, M., Shulaw, W., Thompson, R. C., Fayer, R. and Lal, A. A. (1999). Genetic diversity within Cryptosporidium parvum and related Cryptosporidium species. Applied and Environmental Microbiology 65, 33863391.
Xiao, L., Bern, C., Arrowood, M., Sulaiman, I., Zhou, L., Kawai, V., Vivar, A., Lal, A. A. and Gilman, R. H. (2002 a). Identification of the Cryptosporidium pig genotype in a human patient. Journal of Infectious Diseases 185, 18461848.
Xiao, L., Sulaiman, I. M., Ryan, U. M., Zhou, L., Atwill, E. R., Tischler, M. L., Zhang, X., Fayer, R. and Lal, A. A. (2002 b). Host adaptation and host-parasite co-evolution in Cryptosporidium: implications for taxonomy and public health. International Journal of Parasitology 32, 17731785.
Xiao, L., Fayer, R., Ryan, U. and Upton, S. J. (2004). Cryptosporidium taxonomy: recent advances and implications for public health. Clinical Microbiology Reviews 17, 7297.
Xiao, L., Moore, J. E., Ukoh, U., Gatei, W., Lowery, C. J., Murphy, T. M., Dooley, J. S., Millar, B. C., Rooney, P. J. and Rao, J. R. (2006). Prevalence and identity of Cryptosporidium spp. in pig slurry. Applied and Environmental Microbiology 72, 44614463.
Xiao, L., Fayer, R., Ryan, U. and Upton, S. J. (2007). Response to the newly proposed species Cryptosporidium pestis . Trends in Parasitology 23, 4142.
Yang, R., Jacobson, C., Gordon, C. and Ryan, U. (2009). Prevalence and molecular characterisation of Cryptosporidium and Giardia species in pre-weaned sheep in Australia. Veterinary Parasitology 161, 1924.
Yang, R., Murphy, C., Song, Y., Ng-Hublin, J., Estcourt, A., Hijjawi, N., Chalmers, R., Hadfield, S., Bath, A., Gordon, C. and Ryan, U. (2013). Specific and quantitative detection and identification of Cryptosporidium hominis and C. parvum in clinical and environmental samples. Experimental Parasitology 135, 142147.
Yang, R., Jacobson, C., Gardner, G., Carmichael, I., Campbell, A. J., Ng-Hublin, J. and Ryan, U. (2014). Longitudinal prevalence, oocyst shedding and molecular characterisation of Cryptosporidium species in sheep across four states in Australia. Veterinary Parasitology 200, 5058.
Ye, J., Xiao, L., Wang, Y., Wang, L., Amer, S., Roellig, D. M., Guo, Y., and Feng, Y. (2013). Periparturient transmission of Cryptosporidium xiaoi from ewes to lambs. Veterinary Parasitology 197, 627633.
Yin, J., Shen, Y., Yuan, Z., Lu, W., Xu, Y. and Cao, J. (2011). Prevalence of the Cryptosporidium pig genotype II in pigs from the Yangtze River Delta, China. PLOS ONE 6, e20738.
Yui, T., Nakajima, T., Yamamoto, N., Kon, M., Abe, N., Matsubayashi, M. and Shibahara, T. (2014). Age-related detection and molecular characterization of Cryptosporidium suis and Cryptosporidium scrofarum in pre- and post-weaned piglets and adult pigs in Japan. Parasitology Research 113, 359365.
Zhang, W., Wang, R., Yang, F., Zhang, L., Cao, J., Zhang, X., Ling, H., Liu, A. and Shen, Y. (2013 a). Distribution and genetic characterizations of Cryptosporidium spp. in pre-weaned dairy calves in Northeastern China's Heilongjiang Province. PLOS ONE 8, e54857.
Zhang, W., Yang, F., Liu, A., Wang, R., Zhang, L., Shen, Y., Cao, J. and Ling, H. (2013 b). Prevalence and genetic characterizations of Cryptosporidium spp. in pre-weaned and post-weaned piglets in Heilongjiang Province, China. PLOS ONE 8, e67564.
Zhao, G. H., Ren, W. X., Gao, M., Bian, Q. Q., Hu, B., Cong, M. M., Lin, Q., Wang, R. J., Qi, M., Qi, M. Z., Zhu, X. Q. and Zhang, L. X. (2013). Genotyping Cryptosporidium andersoni in cattle in Shaanxi Province, Northwestern China. PLOS ONE 8, e60112.
Zintl, A., Neville, D., Maguire, D., Fanning, S., Mulcahy, G., Smith, H. V. and De Waal, T. (2007). Prevalence of Cryptosporidium species in intensively farmed pigs in Ireland. Parasitology 134, 15751582.
Zintl, A., Proctor, A. F., Read, C., Dewaal, T., Shanaghy, N., Fanning, S. and Mulcahy, G. (2009). The prevalence of Cryptosporidium species and subtypes in human faecal samples in Ireland. Epidemiology and Infection 137, 270277.
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Parasitology
  • ISSN: 0031-1820
  • EISSN: 1469-8161
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