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Global distribution of Echinococcus granulosus genotypes in domestic and wild canids: a systematic review and meta-analysis

Published online by Cambridge University Press:  20 May 2022

Morteza Shams Open the ORCID record for Morteza Shams [Opens in a new window] ,
Sasan Khazaei ,
Razi Naserifar Open the ORCID record for Razi Naserifar [Opens in a new window] ,
Seyyed Ali Shariatzadeh ,
Davood Anvari Open the ORCID record for Davood Anvari [Opens in a new window] ,
Fattaneh Montazeri ,
Majid Pirestani  and
Hamidreza Majidiani
Morteza Shams*
Affiliation:
Zoonotic Diseases Research Center, Ilam University of Medical Sciences, Ilam, Iran Student Research Committee, Ilam University of Medical Sciences, Ilam, Iran
Sasan Khazaei
Affiliation:
Department of Parasitology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
Razi Naserifar
Affiliation:
Zoonotic Diseases Research Center, Ilam University of Medical Sciences, Ilam, Iran
Seyyed Ali Shariatzadeh
Affiliation:
Department of Parasitology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran Student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran
Davood Anvari
Affiliation:
School of Medicine, Iranshahr University of Medical Sciences, Iranshahr, Iran
Fattaneh Montazeri
Affiliation:
Department of Parasitology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
Majid Pirestani
Affiliation:
Department of Parasitology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
Hamidreza Majidiani*
Affiliation:
Department of Basic Medical Sciences, Neyshabur University of Medical Sciences, Neyshabur, Iran
*
Authors for correspondence: Morteza Shams, E-mail: Shamsimorteza55@gmail.com; Hamidreza Majidiani, E-mail: Majidianih1@nums.ac.ir
Authors for correspondence: Morteza Shams, E-mail: Shamsimorteza55@gmail.com; Hamidreza Majidiani, E-mail: Majidianih1@nums.ac.ir
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Abstract

The current systematic review and meta-analysis demonstrate the genotypic distribution of canine echinococcosis worldwide. Studies published from the inception until 21 May 2021 were screened, relevant articles were selected and the random-effect model was used to draw forest plots with 95% confidence intervals (CIs). Totally, 44 articles were included, mostly examined dogs (37 records), followed by wolf (8 records), jackal (7 records), fox (3 records), pump fox (3 records) and coyote (1 record). Echinococcus granulosus sensu stricto (G1–G3) and G6/7 cluster of Echinococcus canadensis were the most common genotypes among canids. Most studies were conducted in Asia and Europe with 17 and 15 datasets, respectively. Exclusively, Iran possessed the highest number of studies (10 records). Meta-analysis showed that the pooled molecular prevalence of echinococcosis was 33.82% (95% CI 24.50–43.83%). Also, the highest and lowest prevalence of canine echinococcosis was calculated for South America (66.03%; 95% CI 25.67–95.85%) and Europe (19.01%; 95% CI 9.95–30.16%). Additionally, there were statistically significant differences between the global prevalence of echinococcosis in canines and publication year, continent, country, sample type, host and molecular test. These findings will elevate our knowledge on the poorly known canine echinococcosis worldwide.

Keywords

Canine echinococcosisE. canadensisE. granulosus sensu latoE. granulosus sensu strictogenotype diversitymeta-analysissystematic review

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Type
Review Article
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Parasitology , Volume 149 , Issue 9 , August 2022 , pp. 1147 - 1159
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Copyright © The Author(s), 2022. Published by Cambridge University Press

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