Llewellyn, Stacey Inpankaew, Tawin Nery, Susana Vaz Gray, Darren J. Verweij, Jaco J. Clements, Archie C. A. Gomes, Santina J. Traub, Rebecca McCarthy, James S. and Bethony, Jeffrey Michael 2016. Application of a Multiplex Quantitative PCR to Assess Prevalence and Intensity Of Intestinal Parasite Infections in a Controlled Clinical Trial. PLOS Neglected Tropical Diseases, Vol. 10, Issue. 1, p. e0004380.
Truscott, J.E. Turner, H.C. Farrell, S.H. and Anderson, R.M. 2016. Mathematical Models for Neglected Tropical Diseases - Essential Tools for Control and Elimination, Part B.
Brooker, Simon J. and Bundy, Donald A.P. 2014. Manson's Tropical Infectious Diseases.
Garira, Winston Mathebula, Dephney and Netshikweta, Rendani 2014. A mathematical modelling framework for linked within-host and between-host dynamics for infections with free-living pathogens in the environment. Mathematical Biosciences, Vol. 256, p. 58.
Wammes, Linda J Mpairwe, Harriet Elliott, Alison M and Yazdanbakhsh, Maria 2014. Helminth therapy or elimination: epidemiological, immunological, and clinical considerations. The Lancet Infectious Diseases, Vol. 14, Issue. 11, p. 1150.
Bundy, Donald A P de Silva, Nilanthi and Brooker, Simon 2013. Hunter's Tropical Medicine and Emerging Infectious Disease.
Walker, Martin Hall, Andrew and Basáñez, María-Gloria 2013. Ascaris: The Neglected Parasite.
Florey, Lia S. King, Charles H. Van Dyke, Melissa K. Muchiri, Eric M. Mungai, Peter L. Zimmerman, Peter A. Wilson, Mark L. and Brooker, Simon 2012. Partnering Parasites: Evidence of Synergism between Heavy Schistosoma haematobium and Plasmodium Species Infections in Kenyan Children. PLoS Neglected Tropical Diseases, Vol. 6, Issue. 7, p. e1723.
Okech, B.A. and Mwandawiro, C.S. 2011. Encyclopedia of Environmental Health.
Walker, Martin Hall, Andrew Basáñez, María-Gloria and Diemert, David Joseph 2011. Individual Predisposition, Household Clustering and Risk Factors for Human Infection with Ascaris lumbricoides: New Epidemiological Insights. PLoS Neglected Tropical Diseases, Vol. 5, Issue. 4, p. e1047.
Brooker, Simon 2010. Estimating the global distribution and disease burden of intestinal nematode infections: Adding up the numbers – A review. International Journal for Parasitology, Vol. 40, Issue. 10, p. 1137.
Cox, F.E.G. and Wakelin, Derek 2010. Topley & Wilson's Microbiology and Microbial Infections.
Holland, Celia V. 2010. Topley & Wilson's Microbiology and Microbial Infections.
Jardim-Botelho, Anne Brooker, Simon Geiger, Stefan Michael Fleming, Fiona Souza Lopes, Aline Cristine Diemert, David Joseph Corrêa-Oliveira, Rodrigo and Bethony, Jeffrey Michael 2008. Age patterns in undernutrition and helminth infection in a rural area of Brazil: associations with ascariasis and hookworm. Tropical Medicine & International Health, Vol. 13, Issue. 4, p. 458.
Pullan, Rachel L. Bethony, Jeffrey M. Geiger, Stefan M. Cundill, Bonnie Correa-Oliveira, Rodrigo Quinnell, Rupert J. Brooker, Simon and Raso, Giovanna 2008. Human Helminth Co-Infection: Analysis of Spatial Patterns and Risk Factors in a Brazilian Community. PLoS Neglected Tropical Diseases, Vol. 2, Issue. 12, p. e352.
PULLAN, R. and BROOKER, S. 2008. The health impact of polyparasitism in humans: are we under-estimating the burden of parasitic diseases?. Parasitology, Vol. 135, Issue. 07,
Kolaczinski, Jan H. Kabatereine, Narcis B. Onapa, Ambrose W. Ndyomugyenyi, Richard Kakembo, Abbas S.L. and Brooker, Simon 2007. Neglected tropical diseases in Uganda: the prospect and challenge of integrated control. Trends in Parasitology, Vol. 23, Issue. 10, p. 485.
Brooker, Simon Alexander, Neal Geiger, Stefan Moyeed, Rana A. Stander, Julian Fleming, Fiona Hotez, Peter J. Correa-Oliveira, Rodrigo and Bethony, Jeffrey 2006. Contrasting patterns in the small-scale heterogeneity of human helminth infections in urban and rural environments in Brazil. International Journal for Parasitology, Vol. 36, Issue. 10-11, p. 1143.
Brooker, S. Clements, A.C.A. and Bundy, D.A.P. 2006. Global Mapping of Infectious Diseases: Methods, Examples and Emerging Applications.
TORGERSON, P. R. 2006. Canid immunity to Echinococcus spp.: impact on transmission. Parasite Immunology, Vol. 28, Issue. 7, p. 295.
The morbidity and transmission dynamics of geohelminthiases are determined by the patterns of infection intensity in the community. Understanding the determinants of these patterns requires a combination of field, laboratory and theoretical study. Studies of age-specific reinfection, and of the phenomenon of predisposition, indicate that the major determinant of convex age-intensity profiles and of heterogeneity in infection intensity is the rate of establishment of infection, rather than the rate of adult worm mortality. The rate of establishment is, in turn, determined by exposure to, and protection from, infection. The evidence indicates that exposure, at least to the orally-transmitted geohelminths, varies with age and is highly heterogeneous between hosts. The immune response in geohelminthiasis is vigorous, parasite-specific, hetero geneous between hosts, and both age and infection dose dependent, but has yet to be convincingly shown to be protective. Since the immune response is itself a function of exposure, unravelling the interaction between ecology and immunology as determinants of geohelminth worm burden will require simultaneous assessment of both processes via immuno epidemiological study.
This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.
Email your librarian or administrator to recommend adding this journal to your organisation's collection.
Full text views reflects the number of PDF downloads, PDFs sent to Google Drive, Dropbox and Kindle and HTML full text views.
Abstract views reflect the number of visits to the article landing page.
* Views captured on Cambridge Core between September 2016 - 26th May 2017. This data will be updated every 24 hours.