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Process evaluation of schistosomiasis control in Uganda, 2003 to 2006: perceptions, attitudes and constraints of a national programme

  • F. M. FLEMING (a1), A. FENWICK (a1), E. M. TUKAHEBWA (a2), R. G. N. LUBANGA (a3), H. NAMWANGYE (a2), S. ZARAMBA (a4) and N. B. KABATEREINE (a2)
  • DOI:
  • Published online: 21 August 2009

Schistosomiasis is widespread in Uganda along large lakes and rivers with approximately 4 million people infected. Hookworm infections also prevalent throughout the country, while infections with Ascaris lumbricoides and Trichuris trichiura are mainly found in south-western Uganda. A national programme aimed at controlling morbidity due to these infections was launched in 2003. This article describes the perceptions, attitudes, constraints and experiences of those implementing the programme and those receiving the treatment. The study used qualitative data collected largely in two districts but also from 18 other districts implementing the programme. Results showed that mass treatment was perceived to be beneficial because the drugs make people feel better. However, side-effects of praziquantel (PZQ), the smell and size of the tablets and the use of height, not weight, to determine dose were raised as major factors discouraging people from taking the drug. Generally, most of the end-users were appreciative of the programme and were beginning to demand regular treatment. Nevertheless, intensive and sustained health education is still vital for improvement of treatment coverage, especially among the non-compliers. It was repeatedly highlighted that there is a need to stock PZQ in all health facilities in endemic areas. Provision of incentives to drug distributors and to involve as many stakeholders as possible in the planning phase were also raised by respondents. Lessons learned for the development and success of a helminth control programme at a national scale are discussed.

Corresponding author
*Corresponding author: Schistosomiasis Control Initiative, Department of Infectious Disease Epidemiology, Imperial College London, St. Mary's Campus, Norfolk Place, London, W2 1PG, UK. Tel: +44 (0)20 7594 3626; Fax: +44 (0)20 7262 8140. E-mail:
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S. O. Asaolu and I. E. Ofoezie (2003). The role of health educations and sanitation in the control of helminth infections. Acta Tropica 86, 283294.

S. Brooker , N. B. Kabatereine , F. Fleming and N. Devlin (2008). Cost and cost-effectiveness of nationwide school-based helminth control in Uganda: intra-country variation and effects of scaling-up. Health Policy and Planning 23, 2435.

S. Brooker , H. Marriot , A. Hall , S. Adjei , E. Allan , C. Maier , D. A. P. Bundy , L. J. Drake , M. D. Coombes , G. Azene , R. G. Lansdown , S. T. Wen , M. Dzodemenyo , J. Cobbinah , N. Obro , C. M. Kihamia , W. Issae , L. Mwanri , M. R. Mweta , A. Mwaikemwa , M. Salimu , P. Ntimbwa , V. M. Kiwelu , A. Turuka , D. R. Nkungu and J. Magingo (2001). Community perception of school-based delivery of anthelmintics in Ghana and Tanzania. Tropical Medicine and International Health 6, 10751083.

A. Danso-Appiah , S. J. de Vlas , K. M. Bosompem and J. D. F. Habbema (2004). Determinants of health-seeking behaviour for schistosomiasis-related symptoms in the context of integrating schistosomiasis control within the regular health services in Ghana. Tropical Medicine and International Health 9, 784794.

B. Gryseels , K. Polman , J. Clerinx and L. Kestens (2006). Human schistosomiasis. Lancet 368, 11061118.

N. B. Kabatereine , S. Brooker , E. M. Tukahebwa , F. Kazibwe and A. W. Onapa (2004). Epidemiology and geography of Schistosoma mansoni in Uganda: implications for planning control. Tropical Medicine and International Health 9, 372380.

N. K. Kabatereine , F. M. Fleming , U. Nyandindi , J. C. L. Mwanza and L. Blair (2006 b). The control of schistosomiasis and soil-transmitted helminths in East Africa. Trends in Parasitology 22, 332339.

N. B. Kabatereine , J. Kemijumba , J. H. Ouma , R. F. Sturrock , A. E. Butterworth , H. Madsen , N. Ørnbjerg , D. W. Dunne and B. J. Vennervald (2003). Efficacy and side-effects of praziquantel treatment in a highly endemic Schistosoma mansoni focus at Lake Albert, Uganda. Transactions of the Royal Society of Tropical Medicine and Hygiene 97, 599603.

N. B. Kabatereine , E. Tukahebwa , F. Kazibwe , H. Namwangye , S. Zaramba , S. Brooker , J. R. Stothard , C. Kamenka , S. Whawell , J. P. Webster and A. Fenwick (2006 a). Progress towards countrywide control of schistosomiasis and soil-transmitted helminthiasis in Uganda. Transactions of the Royal Society of Tropical Medicine and Hygiene 100, 208215.

N. B. Kabatereine , E. M. Tukahebwa , F. Kazibwe , J. M. Twa-Twa , J. F. Barenzi , S. Zaramba , J. R. Stothard , A. Fenwick and S. Brooker (2005). Soil-transmitted helminthiasis in Uganda: epidemiology and cost of control. Tropical Medicine and International Health 10, 11871189.

M. N Katabarwa , D. Mutabazi and F. O. Richards Jr. (1999). The community-directed, ivermectin-treatment programme for onchocerciasis control in Uganda–an evaluative study (1993–1997). Annals of Tropical Medicine and Parasitology 93, 727735.

A. Landouré , M. J. van der Werf , M. Traoré and S. J. de Vlas (2003). Evaluation of case management in the integrated schistosomiasis-control programme in Mali. Annals of Tropical Medicine and Parasitology 97, 723736.

R. Lansdown , A. Ledward , A. Hall , W. Issae , E. Yona , J. Matulu , M. Mweta , C. Kihamia , U. Nyandindi and D. Bundy (2002). Schistosomiasis, helminth infection and health education in Tanzania: achieving behaviour change in primary schools. Health Education Research 17, 425433.

A. Montresor , D. Engels , L. Chitsulo , D. A. P. Bundy , S. Brooker and L. Savioli (2001). Development and validation of a ‘tablet pole’ for the administration of praziquantel in sub-Saharan Africa. Transactions of the Royal Society of Tropical Medicine and Hygiene 95, 542544.

F. Nuwaha , J. Okware and R. Ndyomugyenyi (2005). Predictors of compliance with community-directed ivermectin treatment in Uganda: quantitative results. Tropical Medicine and International Health 10, 659667.

O. C. Nwaorgu , J. Okeibunor , E. Madu , U. Amazigo , N. Onyegegbu and D. Evans (1998). A school-based schistosomiasis and intestinal helminthiasis control programme in Nigeria: acceptability to community members. Tropical Medicine and International Health 3, 842849.

G. Poggensee , I. Krantz , P. Nordin , S. Mtweve , B. Ahlberg , G. Mosha and S. Freudenthal (2005). A six-year follow-up of schoolchildren for urinary and intestinal schistosomiasis and soil-transmitted helminthiasis in Northern Tanzania. Acta Tropica 93, 131140.

G. Raso , E. K. N'Goran , A. Toty , A. Luginbühl , C. A. Adjoua , N. T. Tian-Bi , I. I. Bogoch , P. Vounatsou , M. Tanner and J. Utzinger (2004). Efficacy and side-effects of praziquantel against Schistosoma mansoni in a community of western Côte d'Ivoire. Transactions of the Royal Society of Tropical Medicine and Hygiene 98, 1824.

J. Utzinger , R. Bergquist , S. H. Xiao , B. H. Singer and M. Tanner (2003). Schistosomiasis control – the way forward. Lancet 362, 19321934.

M. J. van der Werf , S. J. de Vlas , A. Landouré , K. M. Bosompem and J. D. F. Habbema (2004). Measuring schistosomiasis case management of the health services in Ghana and Mali. Tropical Medicine and International Health 9, 149157.

L. Wang , J. Utzinger and X. N. Zhou (2008). Schistosomiasis control – experience and lessons from China. Lancet 372, 17931795.

X. N. Zhou , L. Y. Wang , M. G. Chen , X. H. Wu , Q. W. Jiang , X. Y. Chen , J. Zheng and J. Utzinger (2005). The public health significance and control of schistosomiasis in China–then and now. Acta Tropica 96, 97105.

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