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Quinanil as a Bactericidal Agent in the Isolation of an Insect Flagellate

Published online by Cambridge University Press:  06 April 2009

G. N. Boxhall ,
F. C. Happold  and
Ll. Lloyd
G. N. Boxhall
Affiliation:
From the Departments of Pathology and Bacteriology and Department of Zoology, University of Leeds
F. C. Happold
Affiliation:
From the Departments of Pathology and Bacteriology and Department of Zoology, University of Leeds
Ll. Lloyd
Affiliation:
From the Departments of Pathology and Bacteriology and Department of Zoology, University of Leeds
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Extract

A flagellate from Polietes lardaria, closely allied to Herpetomonas muscarum, has been repeatedly isolated in bacteria-free culture by the use of quinanil after numerous attempts to isolate it by other methods with one exception had failed. The flagellates were exposed to 1/10,000 or 1/100,000 quinanil for 2–4 or more hours and cultivated in Locke serum agar, the medium for the first subculture containing quinanil in concentrations of 1/10,000 or 1/50,000. The proofs of the purity of the cultures were exhaustive.

We are greatly indebted to Dr St John-Brooks and the National Collection of Type Cultures for certain of the flagellates isolated by Noguchi and Tilden. One of us (F. C. H.) has also been in receipt of grants from the Medical Research Council, and he would like to take this opportunity of expressing his thanks to that body.

Type
Research Article
Information
Parasitology , Volume 26 , Issue 1 , April 1934 , pp. 44 - 48
Copyright
Copyright © Cambridge University Press 1934

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References

Anderson, J., Happold, F. C., Mcleod, J. W. and Thomson, J. G. (1931). On the existence of two forms of diphtheria bacillus, B. diphtheria gravis and B. diphtheria mitis, and a new medium for their differentiation and for the bacteriological diagnosis of diphtheria. J. Path. and Bact. 34, 667.CrossRefGoogle Scholar
Armitage, G., Gordon, J., Cohen, J. B., Ellingworth, S. and Dobson, J. (1929). The use of a new quinoline derivative in the treatment of infection. Lancet, ii, 968.CrossRefGoogle Scholar
Bishop, A. (1931). The morphology and method of division of Trichomonas. Parasitology, 23, 129.CrossRefGoogle Scholar
Browning, C. H., Cohen, J. B., Ellingworth, S. and Gulbranson, R. (1929). Trypanocidal action of some derivatives of anil and styryl quinoline. Proc. Roy. Soc. B, 105, 99.Google Scholar
Dobell, C. and Laidlaw, P. P. (1926). On the cultivation of Entamoeba histolytica and some other entozoic amoebae. Parasitology, 18, 283.CrossRefGoogle Scholar
Drbohlav, J. J. (1926). The cultivation of H. muscarum from Lucilia sericata. J. Parasitol. 12, 183.Google Scholar
Jameson, A. P. (1927). The behaviour of Balantidium coli Malm. in cultures. Parasitology, 19, 411.Google Scholar
Keilin, D. and Tate, P. (1930). On certain semi-carnivorous anthomyid larvae. Parasitology. 22, 168.CrossRefGoogle Scholar
Koch, D. A. (1926). An experimental study of the effects of dyes and dye mixtures upon Endamoeba gingivalis (Gros) in vitro. Univ. Calif. Publ. Zool. 29, No. 11.Google Scholar
Luck, J. M. and Sheets, G. (1931). The sterilisation of Protozoa. Arch. Protistenk. 75, 255.Google Scholar
Mackinnon, D. L. (1910). Herpetomonads from the alimentary tract of certain dung flies. Parasitology, 3, 255.Google Scholar
Noguchi, H. and Tilden, E. B. (1926). Comparative studies of Herpetomonads and Leishmanias. I. Cultivation of Herpetomonads from insects and plants. J. Exp. Med. 44, 307.CrossRefGoogle ScholarPubMed
NÖller, W. (1917). Blut- und Insektenflagellatenzüchtung auf Platten. Arch. Schiffs- u. Tropenhyg. 21, 53.Google Scholar
Novy, F. G., MacNeal, W. J. and Torrey, H. N. (1907). The trypanosomes of mosquitoes and other insects. J. Inf. Dis. 4, 223.CrossRefGoogle Scholar
Weiss, D. and Weiss, C. (1926). Experiments on the purification of cultures of S. pallida by chemical methods. J. Inf. Dis.. 38, 281.CrossRefGoogle Scholar
Wenyon, C. M. (1926). Protozoology. London.Google Scholar