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Defining Dysfunction: Natural Selection, Design, and Drawing a Line

Published online by Cambridge University Press:  01 January 2022

Abstract

Accounts of the concepts of function and dysfunction have not adequately explained what factors determine the line between low-normal function and dysfunction. I call the challenge of doing so the line-drawing problem. Previous approaches emphasize facts involving the action of natural selection (Wakefield 1992a, 1999a, 1999b) or the statistical distribution of levels of functioning in the current population (Boorse 1977, 1997). I point out limitations of these two approaches and present a solution to the line-drawing problem that builds on the second one.

Type
Research Article
Copyright
Copyright © The Philosophy of Science Association

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Footnotes

Thanks to Christopher Boorse, Randall Dipert, Gary Ebbs, Gary Hatfield, Harold Kincaid, Eric Meslin, Shari Rudavsky, and Alfred Tauber for conversation and encouragement regarding my work on these issues. Thanks to two anonymous reviewers for Philosophy of Science for critique and questions that significantly contributed to the final product. Thanks also to audiences at the University of Alabama, Birmingham, the University of Buffalo, and Indiana University–Purdue University, Indianapolis (IUPUI), where I presented earlier versions of this paper.

References

Allen, Collin, and Bekoff, Marc (1995), “Biological Function, Adaptation, and Natural Design”, Biological Function, Adaptation, and Natural Design 62:609622.Google Scholar
Boorse, Christopher (1976), “Wright on Functions”, Wright on Functions 85:7086.Google Scholar
Boorse, Christopher (1977), “Health as a Theoretical Concept”, Health as a Theoretical Concept 44:542573.Google Scholar
Boorse, Christopher (1987), “Concepts of Health”, in Van De Veer, D. and Regan, T. (eds.), Health Care Ethics: An Introduction. Philadelphia: Temple University Press, 359393.Google Scholar
Boorse, Christopher (1997), “A Rebuttal on Health”, in Humber, J. M. and Almeder, R. F. (eds.), What Is Disease? Totowa, NJ: Humana Press, 1134.Google Scholar
Boorse, Christopher (2002), “A Rebuttal on Functions”, in Ariew, A., Cummins, R., and Perlman, M. (eds.), Functions: New Readings in the Philosophy of Psychology and Biology. Oxford: Oxford University Press, 63112.Google Scholar
Bosch, J. L. H., et al. (1995), “Natural History of Benign Prostatic Hyperplasia: Appropriate Case Definition and Estimation of Its Prevalence in the Community”, Natural History of Benign Prostatic Hyperplasia: Appropriate Case Definition and Estimation of Its Prevalence in the Community 46 (Supplement 3A): 3440.Google Scholar
Buchanan, Allen, et al. (2000), From Chance to Choice: Genetics and Justice. Cambridge: Cambridge University Press.CrossRefGoogle Scholar
Caplan, Arthur (2004), “The ‘Unnaturalness’ of Aging—Give Me Reason to Live!”, in Caplan, A. L. and McCartney, J. J. (eds.), Health, Disease, and Illness: Concepts in Medicine. Washington, DC: Georgetown University Press, 117127.Google Scholar
Culver, Charles, and Gert, Bernard (1982), Philosophy in Medicine: Conceptual and Ethical Issues in Medicine and Psychiatry. New York: Oxford University Press.Google Scholar
Cummins, Robert (1975), “Functional Analysis”, Functional Analysis 72:741764.Google Scholar
Daniels, Norman (1985), Just Health Care. Cambridge: Cambridge University Press.CrossRefGoogle ScholarPubMed
Dennett, Daniel C. (1995), Darwin’s Dangerous Idea. New York: Touchstone, Simon and Schuster.Google Scholar
Gert, Bernard, Culver, Charles M., and Clouser, K. Danner (1997), Bioethics: A Return to Fundamentals. New York: Oxford University Press.Google Scholar
Lewens, Tim (2004), Organisms and Artifacts: Design in Nature and Elsewhere. Cambridge, MA: MIT Press.CrossRefGoogle Scholar
Lewontin, Richard (1983), “Gene, Organism and Environment”, in Bendall, D. S. (ed.), Evolution from Molecules to Men. Cambridge: Cambridge University Press, 273285.Google Scholar
Lilienfeld, Scott, and Marino, Lori (1995), “Mental Disorder as a Roschian Concept: A Critique of Wakefield’s ‘Harmful Dysfunction’ Analysis”, Mental Disorder as a Roschian Concept: A Critique of Wakefield’s ‘Harmful Dysfunction’ Analysis 104:411420.Google Scholar
Matthen, Mohan, (1997), “Teleology and the Product Analogy”, Teleology and the Product Analogy 75:2137.Google Scholar
Millikan, Ruth Garrett (1989), “In Defense of Proper Functions”, In Defense of Proper Functions 56:288302.Google Scholar
Neander, Karen (1991), “Functions as Selected Effects: The Conceptual Analyst’s Defense”, Functions as Selected Effects: The Conceptual Analyst’s Defense 58:168184.Google Scholar
Neander, Karen (1995), “Misrepresenting and Malfunctioning”, Misrepresenting and Malfunctioning 79:109141.Google Scholar
Polvikoski, T., et al. (2001), “Prevalence of Alzheimer’s Disease in Very Elderly People: A Prospective Neuropathological Study”, Prevalence of Alzheimer’s Disease in Very Elderly People: A Prospective Neuropathological Study 56:16901696.Google ScholarPubMed
Ramsey, William (1992), “Prototypes and Conceptual Analysis”, Prototypes and Conceptual Analysis 11:5970.Google Scholar
Rettenmaier, J. L., et al. (2002), “Prevalence of Canine Hip Dysplasia in a Veterinary Teaching Hospital Population”, Prevalence of Canine Hip Dysplasia in a Veterinary Teaching Hospital Population 43:313318.Google Scholar
Schwartz, Peter H. (2004), “Moving beyond Conceptual Analysis in the Function Debate”, Moving beyond Conceptual Analysis in the Function Debate 87:136153.Google Scholar
Schwartz, Peter H. (2007), “Decision and Discovery in Defining `Disease'”, in Kincaid, H. and McKitrick, J. (eds.), Establishing Medical Reality: Essays in the Metaphysics and Epistemology of Biomedical Science. Dordrecht: Springer, 4764.CrossRefGoogle Scholar
Wakefield, Jerome C. (1992a), “The Concept of Mental Disorder: On the Boundary between Biological Facts and Social Values”, The Concept of Mental Disorder: On the Boundary between Biological Facts and Social Values 47:373388.Google Scholar
Wakefield, Jerome C. (1992b), “Disorder as Harmful Dysfunction: A Conceptual Critique of DSM-III-R’s Definition of Mental Disorder”, Disorder as Harmful Dysfunction: A Conceptual Critique of DSM-III-R’s Definition of Mental Disorder 99:232247.Google Scholar
Wakefield, Jerome C. (1999a), “Evolutionary versus Prototype Analyses of the Concept of Disorder”, Evolutionary versus Prototype Analyses of the Concept of Disorder 108:374399.Google Scholar
Wakefield, Jerome C. (1999b), “Mental Disorder as a Black Box Essentialist Concept”, Mental Disorder as a Black Box Essentialist Concept 108:465472.Google Scholar