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Pathways to Biomedical Discovery

Published online by Cambridge University Press:  01 January 2022

Paul Thagard
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Abstract

A biochemical pathway is a sequence of chemical reactions in a biological organism. Such pathways specify mechanisms that explain how cells carry out their major functions by means of molecules and reactions that produce regular changes. Many diseases can be explained by defects in pathways, and new treatments often involve finding drugs that correct those defects. This paper presents explanation schemas and treatment strategies that characterize how thinking about pathways contributes to biomedical discovery. It discusses the significance of pathways for understanding the nature of diseases, explanations, and theories.

Type
Research Article
Information
Philosophy of Science , Volume 70 , Issue 2 , April 2003 , pp. 235 - 254
Copyright
Copyright © The Philosophy of Science Association

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Footnotes

‡

I am grateful to Lindley Darden and two anonymous referees for very helpful suggestions. This research is supported by the Natural Sciences and Engineering Research Council of Canada.

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