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Dietary fibre and colon cancer: where do we go from here?

  • Michael Hill (a1)
  • DOI: http://dx.doi.org/10.1079/PNS2002238
  • Published online: 05 March 2007
Abstract

The relationship between intake of dietary fibre and risk of colon cancer has been studied for 30 years and still the data are inconclusive. There are many possible reasons for this outcome, and they include a failure to consider exposure to dietary fibre separately by source, or colon cancers separately by subsite. These potential confounders have been known for at least 20 years. However, the disease is normally considered by epidemiologists as a single entity. More recently, it has become clear that colon cancer can arise via various histological pathways, and by various genetic pathways. There is no reason at all for assuming that risk factors for these possible pathways are the same. There is a need, therefore, for a more detailed approach to the study of diet and colon cancer, with fibre source and cancer subsite, genetic pathway and histological pathway taken into account.

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Copyright
Corresponding author
Corresponding author: Professor M. Hill, fax +44 20 7815 8101 or +44 1256 880416 email, michael.hill.ecp@care4free.net, or, hillmj@sbu.ac.uk
Linked references
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This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

MC Boutron-Ruault , P Senesse , S Meance , C Belghiti , J Faivre (2001) Energy intake, body mass index, physical activity and the colorectal adenoma-carcinoma sequence. Nutrition and Cancer 39, 5057.

U de Jong , NE Day , CS Muir , TH Barclay , G Bras , FH Foster , DJ Jussawalla , N Ringertz , T Shanmugaratnam (1972) The distribution of cancer within the large bowel. International Journal of Cancer 10, 463477.

European Cancer, Prevention Consensus Panel (1998) Consensus statement on cereals, fibre and colorectal and breast cancers. European Journal of Cancer Prevention 7, s1s4 Suppl. 2

CS Fuchs , EL Giovannucci , GA Colditz , DJ Hunter , MJ Stampfer , B Rosner , FE Speizer , WC Willett (1999) Dietary fiber and the risk of colorectal cancer and adenoma in women. New England Journal of Medicine 340, 169176.

MJ Hill (1997) Cereals, cereal fibre and colorectal cancer risk: a review of the epidemiological literature. European Journal of Cancer Prevention 6, 219225.

MJ Hill (2000) Molecular and genetic risk markers in colon cancer trials. European Journal of Cancer 36, 12881291.

MJ Hill (2001) ECP dietary advice on cancer prevention. European Journal of Cancer Prevention 10, 183190.

MJ Hill (2002) Vegetables, fruits, fibres and colorectal cancer. European Journal of Cancer Prevention 11, 12.

MJ Hill , F Fernandez (1990) Bacterial metabolism, fiber and colorectal cancer. In Dietary Fiber: Chemistry, Physiology and Health Effects, pp.417–430 [D Kritchevsky , C Bonfield , JW Anderson , editors]. New York Plenum.

OM Jensen (1984) Different age and sex relationship for cancer of subsites of the large bowel. British Journal of Cancer 50, 825829.

OM Jensen (1989) Dietary fibre, carbohydrate and cancer: epidemiological evidence. In Diet and the Aetiology of Cancer, 21–30 [AB Miller , editors]. Heidelberg, Germany: Springer Verlag.

J Little , L Sharp (2002) Colorectal neoplasia and genetic polymorphisms associated with folate metabolism. European Journal of Cancer Prevention 11, 105110.

S Olschwang (1999) Germline mutation and genome instability. European Journal of Cancer Prevention 8, s33s38 Suppl. 1

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Proceedings of the Nutrition Society
  • ISSN: 0029-6651
  • EISSN: 1475-2719
  • URL: /core/journals/proceedings-of-the-nutrition-society
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