1.United Nations (2015) Department of Economic and Social Affairs, Population Division. World Population Ageing. New York, United States: United Nations.
2.Kirkwood, TBL (2008) A systematic look at an old problem. Nature 451, 644.
3.Pirlich, M & Lochs, H (2001) Nutrition in the elderly. Best Pract Res Clin Gastroenterol 15, 869–884.
4.de Groot, CPGM & van Staveren, WA (2010) Nutritional concerns, health and survival in old age. Biogerontology 11, 597–602.
5.de Groot, LCPGM (2016) Nutritional issues for older adults: addressing degenerative ageing with long-term studies. Proc Nutr Soc 75, 169–173.
6.Moore, K, Hughes, CF, Ward, M et al. (2018) Diet, nutrition and the ageing brain: current evidence and new directions. Proc Nutr Soc 77, 152–163.
7.Ruxton, CHS, Derbyshire, E & Toribio-Mateas, M (2016) Role of fatty acids and micronutrients in healthy ageing: a systematic review of randomised controlled trials set in the context of European dietary surveys of older adults. J Hum Nutr Diet 29, 308–324.
8.Zhu, K, Devine, A, Suleska, A et al. (2010) Adequacy and change in nutrient and food intakes with aging in a seven-year cohort study in elderly women. J Nutr Health Aging 14, 723–729.
9.Wysokiński, A, Sobów, T, Kłoszewska, I et al. (2015) Mechanisms of the anorexia of aging – a review. Age (Omaha) 37, 81.
10.EFSA Panel on Dietetic Products Nutrition and Allergies (2010) Scientific opinion on principles for deriving and applying dietary reference values. EFSA Journal 8, 1458.
11.EFSA Panel on Dietetic Products Nutrition and Allergies (2010) Scientific opinion on dietary reference values for fats, including saturated fatty acids, polyunsaturated fatty acids, monounsaturated fatty acids, trans fatty acids, and cholesterol. EFSA Journal 8, 1461.
12.Nordic Council of Ministers (2014) Nordic Nutrition recommendations 2012. Copenhagen: Nordisk Ministerråd.
13.Department of Health (1991) Dietary reference values for food energy and nutrients for the United Kingdom: report of the Panel on Dietary Reference Values of the Committee on Medical Aspects of Food Policy. United Kingdom: HMSO.
14.Sanders, TAB (2013) Reappraisal of SFA and cardiovascular risk. Proc Nutr Soc 72, 390–398.
15.Calder, PC (2015) Functional roles of fatty acids and their effects on human health. J Parenter Enteral Nutr 39, 18S–32S.
16.Burlingame, B, Nishida, C, Uauy, R et al. (2009) Fats and fatty acids in human nutrition: introduction. Ann Nutr Metab 55, 5–7.
19.Ocké, M, Buurma-Rethans, EJM, de Boer, EJ et al. (2013) Diet of community-dwelling older adults: Dutch National Food Consumption Survey Older Adults 2010–2012. National Institute for Public Health and the Environment.
20.Li, K, McNulty, BA, Tiernery, AM et al. (2016) Dietary fat intakes in Irish adults in 2011: how much has changed in 10 years? Br J Nutr 115, 1798–1809.
21.Carrière, I, Delcourt, C, Lacroux, A et al. (2007) Nutrient Intake in an Elderly Population in Southern France (POLANUT): deficiency in some vitamins, minerals and ω−3 PUFA. Int J Vitam Nutr Res 77, 57–65.
22.EFSA Panel on Dietetic Products Nutrition and Allergies (2012) Scientific opinion on dietary reference values for protein. EFSA Journal 10, 2557.
23.ter Borg, S, Verlaan, S, Mijnarends, DM et al. (2015) Macronutrient intake and inadequacies of community-dwelling older adults, a systematic review. Ann Nutr Metab 66, 242–255.
24.Cruz-Jentoft, AJ, Baeyens, JP, Bauer, JM et al. (2010) Sarcopenia: European consensus on definition and diagnosis Report of the European Working Group on Sarcopenia in Older People. Age Ageing 39, 412–423.
25.Bauer, J, Biolo, G, Cederholm, T et al. (2013) Evidence-based recommendations for optimal dietary protein intake in older people: a position paper from the PROT-AGE study group. J Am Med Dir Assoc 14, 542–559.
26.Nowson, C & O'Connell, S (2015) Protein requirements and recommendations for older people: a review. Nutrients 7, 6874–6899.
27.Gray-Donald, K, Arnaud-McKenzie, DS, Gaudreau, P et al. (2014) Protein intake protects against weight loss in healthy community-dwelling older adults. J Nutr 144, 321–326.
28.Houston, DK, Nicklas, BJ, Ding, J et al. (2008) Dietary protein intake is associated with lean mass change in older, community-dwelling adults: the health, aging, and body composition (Health ABC) study. Am J Clin Nutr 87, 150–155.
29.Granic, A, Mendonça, N, Sayer, AA et al. (2017) Low protein intake, muscle strength and physical performance in the very old: the Newcastle 85+ study. Clin Nutr 37, 2260–2270.
30.Cruz-Jentoft, AJ, Landi, F, Schneider, SM et al. (2014) Prevalence of and interventions for sarcopenia in ageing adults: a systematic review. Report of the International Sarcopenia Initiative (EWGSOP and IWGS). Age Ageing 43, 748–759.
31.EFSA Panel on Dietetic Products Nutrition and Allergies (2010) Scientific opinion on dietary reference values for carbohydrates and dietary fibre. EFSA Journal 8, 1462.
32.Scientific Advisory Committee on Nutrition (2015) Carbohydrates and Health. London: The Stationery Office.
33.World Health Organisation (2015) Sugars intake for adults and children. Geneva, Switzerland: World Health Organisation. 49p.
34.Ruiz, E, Rodriguez, P, Valero, T et al. (2017) Dietary intake of individual (free and intrinsic) sugars and food sources in the Spanish population: findings from the ANIBES study. Nutrients 9, 275.
35.Sluik, D, van Lee, L, Engelen, A et al. (2016) Total, free, and added sugar consumption and adherence to guidelines: the Dutch National Food Consumption Survey 2007–2010. Nutrients 8, 70.
38.Dubuisson, C, Lioret, S, Touvier, M et al. (2010) Trends in food and nutritional intakes of French adults from 1999 to 2007: results from the INCA surveys. Br J Nutr 103, 1035–1048.
39.Szeitz-Szabó, M, Bíró, L, Bíró, G et al. (2011) Dietary survey in Hungary, 2009. Part I. Macronutrients, alcohol, caffeine, fibre. Acta Aliment 40, 142–152.
40.Þorgeirsdóttir, H, Valgeirsdóttir, H, Gunnarsdóttir, I et al. (2011) Hvað borða Íslendingar? Könnun á mataræði Íslendinga 2010–2011 Helstu niðurstöður (A Survey of the diet of Icelanders 2010–2011). Reykjavik: Iceland: Embætti landlæknis, Matvælastofnun, Rannsóknastofa í næringarfræði við Háskóla Íslands, Landspítala-háskólasjúkrahús 2011.
41.Sette, S, Le Donne, C, Piccinelli, R et al. (2011) The third Italian National Food Consumption Survey, INRAN-SCAI 2005–06 – Part 1: nutrient intakes in Italy. Nutr, Metab Cardiovasc Dis 21, 922–932.
42.Barzda, A, Bartkevičiūtė, R, Baltušytė, I et al. (2016) Actual nutrition and nutrition habits of adults and elderly of Lithuania. Visuomenės Sveikata 1, 85–94.
44.Ruiz, E, Ávila, JM, Valero, T et al. (2016) Macronutrient distribution and dietary sources in the Spanish population: findings from the ANIBES study. Nutrients 8, 177.
47.Food Safety Authority of Ireland (2016) Salt and Health: Review of the Scientific Evidence and Recommendations for Public Policy in Ireland (Revision 1) Report No.: 1-904465-23-4. Dublin, Ireland: Food Safety Authority of Ireland.
48.DACH (2013) (Deutsche Gesellschaft für Ernährung – Österreichische Gesellschaft für Ernährung – Schweizerische Gesellschaft für Ernährungsforschung – Schweizerische Vereinigung für Ernährung). Referenzwerte für die Nährstoffzufuhr. Umschau Braus Verlag, Frankfurt am Main, Germany.
49.Strohm, D, Bechthold, A, Ellinger, S et al. (2018) Revised reference values for the intake of sodium and chloride. Ann Nutr Metab 72, 12–17.
50.Giltinan, M, Walton, J, Flynn, A et al. (2011) Report on Salt Intakes in Irish Adults.
52.Cappuccio, FP, Ji, C, Donfrancesco, C et al. (2015) Geographic and socioeconomic variation of sodium and potassium intake in Italy: results from the MINISAL-GIRCSI programme. BMJ Open 5, e007467.
53.Laatikainen, T, Pietinen, P, Valsta, L et al. (2006) Sodium in the Finnish diet: 20-year trends in urinary sodium excretion among the adult population. Eur J Clin Nutr 60, 965.
54.Moreira, P, Sousa, AS, Guerra, RS et al. (2018) Sodium and potassium urinary excretion and their ratio in the elderly: results from the nutrition UP 65 study. Food Nutr Res 62, 10·29219/fnr.v62·1288.
55.Institute of Medicine (2011) Dietary Reference Intakes for Calcium and Vitamin D. Washington, DC: Institute of Medicine.
56.Scientific Advisory Committee on Nutrition (2016) Vitamin D and Health. London: The Stationery Office.
57.Granic, A, Hill, T, Davies, K et al. (2017) Vitamin D status, muscle strength and physical performance decline in very old adults: a prospective study. Nutrients 9, 379.
58.EFSA Panel on Dietetic Products Nutrition and Allergies (2016) Dietary reference values for vitamin D. EFSA Journal 14, e04547.
59.Temme, E, Huybrechts, I, Vandevijvere, S et al. (2010) Energy and macronutrient intakes in Belgium: results from the first National Food Consumption Survey. Br J Nutr 103, 1823–1829.
60.Olza, J, Aranceta-Bartrina, J, González-Gross, M et al. (2017) Reported dietary intake, disparity between the reported consumption and the level needed for adequacy and food sources of calcium, phosphorus, magnesium and vitamin D in the Spanish population: findings from the ANIBES study. Nutrients 9, 168.
61.Brouwer-Brolsma, EM, Vaes, AMM, van der Zwaluw, NL et al. (2016) Relative importance of summer sun exposure, vitamin D intake, and genes to vitamin D status in Dutch older adults: The B-PROOF study. J Steroid Biochem Mol Biol 164, 168–176.
62.Imai, CM, Halldorsson, TI, Eiriksdottir, G et al. (2015) Depression and serum 25-hydroxyvitamin D in older adults living at northern latitudes – AGES-Reykjavik Study. J Nutr Sci 4, e37.
63.Rabenberg, M, Scheidt-Nave, C, Busch, MA et al. (2015) Vitamin D status among adults in Germany – results from the German health interview and examination survey for adults (DEGS1). BMC Public Health 15, 641.
64.Santos, A, Amaral, TF, Guerra, RS et al. (2017) Vitamin D status and associated factors among Portuguese older adults: results from the Nutrition UP 65 cross-sectional study. BMJ Open 7, e016123.
65.Cashman, KD, Muldowney, S, McNulty, B et al. (2013) Vitamin D status of Irish adults: findings from the National Adult Nutrition Survey. Br J Nutr 109, 1248–1256.
66.Ramnemark, A, Norberg, M, Pettersson-Kymmer, U et al. (2015) Adequate vitamin D levels in a Swedish population living above latitude 63°N: the 2009 Northern Sweden MONICA study. Int J Circumpolar Health 74, 27963.
68.Houston, DK, Cesari, M, Ferrucci, L et al. (2007) Association between vitamin D status and physical performance: the InCHIANTI study. J Gerontol, Ser A, Biol Sci Med Sci 62, 440–446.
69.Rodríguez Sangrador, M, Beltrán de Miguel, B, Quintanilla Murillas, L et al. (2008) Contribución de la dieta y la exposición solar al estatus nutricional de vitamina D en españolas de edad avanzada: Estudio de los Cinco Países (Proyecto OPTIFORD). Nutr Hosp 23, 567–576.
70.van Schoor, NM & Lips, P (2011) Worldwide vitamin D status. Best Pract Res Clin Endocrinol Metabol 25, 671–680.
71.Wilcken, B, Bamforth, F, Li, Z et al. (2003) Geographical and ethnic variation of the 677C>T allele of 5,10 methylenetetrahydrofolate reductase (MTHFR): findings from over 7000 newborns from 16 areas world wide. J Med Genet 40, 619–625.
72.EFSA Panel on Dietetic Products Nutrition and Allergies (2016) Dietary reference values for riboflavin. EFSA Journal 15, 4919.
73.Kehoe, L, Walton, J, Hopkins, SM et al. (2018) Intake, status and dietary sources of riboflavin in a representative sample of Irish adults aged 18–90 years. Proc Nutr Soc 77, E66.
74.Mensink, GBM, Fletcher, R, Gurinovic, M et al. (2013) Mapping low intake of micronutrients across Europe. Br J Nutr 110, 755–773.
75.Kehoe, L, Walton, J, Hopkins, SM et al. (2017) Intake, status and dietary sources of riboflavin in a representative sample of Irish adults aged 18–90 years. Proc Nutr 77, e66.
76.EFSA Panel on Dietetic Products Nutrition and Allergies (2014) Scientific opinion on dietary reference values for folate. EFSA Journal 12, 3893.
77.Koike, H, Takahashi, M, Ohyama, K et al. (2015) Clinicopathologic features of folate-deficiency neuropathy. Neurology 84, 1026.
78.Peng, Y, Dong, B & Wang, Z (2016) Serum folate concentrations and all-cause, cardiovascular disease and cancer mortality: a cohort study based on 1999–2010 National Health and Nutrition Examination Survey (NHANES). Int J Cardiol 219, 136–142.
79.Crider, KS, Bailey, LB & Berry, RJ (2011) Folic acid food fortification – its history, effect, concerns, and future directions. Nutrients 3, 370–384.
80.National Toxicology Program (NTP) (2015) Identifying research needs for safe use of high intakes of folic acid. NTP Monograph. U.S. Department of Health and Human Services.
81.ter Borg, S, Verlaan, S, Hemsworth, J et al. (2015) Micronutrient intakes and potential inadequacies of community-dwelling older adults: a systematic review. Br J Nutr 113, 1195–1206.
82.Mendonça, N, Mathers, J, Adamson, A et al. (2016) Intakes of folate and vitamin B12 and biomarkers of status in the very old: the Newcastle 85+ study. Nutrients 8, 604.
83.Laird, EJ, O'Halloran, AM, Carey, D et al. (2018) Voluntary fortification is ineffective to maintain the vitamin B12 and folate status of older Irish adults: evidence from the Irish Longitudinal Study on Ageing (TILDA). Br J Nutr 120, 111–120.
84.Polito, A, Intorre, F, Andriollo-Sanchez, M et al. (2005) Estimation of intake and status of vitamin A, vitamin E and folate in older European adults: the ZENITH. Eur J Clin Nutr 59, S42–SS7.
85.Conzade, R, Koenig, W, Heier, M et al. (2017) Prevalence and predictors of subclinical micronutrient deficiency in German older adults: results from the population-based KORA-age study. Nutrients 9, 1276.
87.Green, R (2011) Indicators for assessing folate and vitamin B-12 status and for monitoring the efficacy of intervention strategies. Am J Clin Nutr 94, 666S–672S.
88.Allen, LH (2009) How common is vitamin B-12 deficiency? Am J Clin Nutr 89, 693S–696S.
89.Hughes, CF, Ward, M, Hoey, L et al. (2013) Vitamin B12 and ageing: current issues and interaction with folate. Ann Clin Biochem 50, 315–329.
90.van Wijngaarden, JP, Doets, EL, Szczecińska, A et al. (2013) Vitamin B(12), folate, homocysteine, and bone health in adults and elderly people: a systematic review with meta-analyses. J Nutr Metab 2013, 486186.
91.Jacobsen, DW (1998) Homocysteine and vitamins in cardiovascular disease. Clin Chem 44, 1833–1843.
92.EFSA Panel on Dietetic Products Nutrition and Allergies (2015) Scientific opinion on dietary reference values for cobalamin (vitamin B12). EFSA Journal 13, 4150.
93.Brouwer-Brolsma, EM, Dhonukshe-Rutten, RAM, van Wijngaarden, JP et al. (2015) Dietary sources of vitamin B-12 and their association with vitamin B-12 status markers in healthy older adults in the B-PROOF study. Nutrients 7, 7781–7797.
94.EFSA Panel on Dietetic Products Nutrition and Allergies (2013) Scientific opinion on dietary reference values for vitamin C. EFSA Journal 11, 3418.
95.Knekt, P, Ritz, J, Pereira, MA et al. (2004) Antioxidant vitamins and coronary heart disease risk: a pooled analysis of 9 cohorts. Am J Clin Nutr 80, 1508–1520.
96.Juraschek, SP, Guallar, E, Appel, LJ et al. (2012) Effects of vitamin C supplementation on blood pressure: a meta-analysis of randomized controlled trials. Am J Clin Nutr 95, 1079–1088.
97.Balboa-Castillo, T, Struijk, EA, Lopez-Garcia, E et al. (2018) Low vitamin intake is associated with risk of frailty in older adults. Age Ageing 47, 872–879.
98.Olza, J, Aranceta-Bartrina, J, González-Gross, M et al. (2017) Reported dietary intake and food sources of zinc, selenium, and vitamins A, E and C in the Spanish population: findings from the ANIBES study. Nutrients 9, 697.
99.EFSA Panel on Dietetic Products Nutrition and Allergies (2015) Scientific opinion on dietary reference values for calcium. EFSA Journal 13, 4101.
100.Price, EA, Mehra, R, Holmes, TH et al. (2011) Anemia in older persons: etiology and evaluation. Blood Cells, Mol Dis 46, 159–165.
101.EFSA Panel on Dietetic Products Nutrition and Allergies (2015) Scientific opinion on dietary reference values for iron. EFSA Journal 13, 4254.
102.del, C, Valdés Hernández, M, Kyle, J et al. (2017) Dietary iodine exposure and brain structures and cognition in older people. Exploratory analysis in the Lothian Birth Cohort 1936. J Nutr Health Aging 21, 971–979.
103.EFSA Panel on Dietetic Products Nutrition and Allergies (2014) Scientific opinion on dietary reference values for iodine. EFSA Journal 12, 3660.
104.McNulty, BA, Nugent, AP, Walton, J et al. (2017) Iodine intakes and status in Irish adults: is there cause for concern? Br J Nutr 117, 422–431.
105.World Health Organization (2004) Iodine Status Worldwide WHO Global Databases on Iodine Deficiency. In [de Benoist, B, Andersson, M, Elgli, I, Takkouche, B and Allen, H, editors]. Geneva, Switzerland: World Health Organization.
106.Dominguez, LJ, Barbagallo, M, Lauretani, F et al. (2006) Magnesium and muscle performance in older persons: the InCHIANTI study. Am J Clin Nutr 84, 419–426.
107.DiNicolantonio, JJ, O'Keefe, JH & Wilson, W (2018) Subclinical magnesium deficiency: a principal driver of cardiovascular disease and a public health crisis. Open Heart 5, e000668.
108.EFSA Panel on Dietetic Products Nutrition and Allergies (2015) Scientific opinion on dietary reference values for magnesium. EFSA Journal 13, 4186.
109.FSAI (2011) Scientific Recommendations for Healthy Eating Guidelines in Ireland. Dublin, Ireland: Food Safety Authority of Ireland. Report No.: 1-904465-76-5.
110.Moore, K, Hughes, CF, Hoey, L et al. (2017) Role of fortification and supplementation in achieving optimal biomarker status of B-vitamins for better mental health in older adults. Proc Nutr Soc 76, E49.
111.Berendsen, AAM, van Lieshout, LELM, van den Heuvel, EGHM et al. (2016) Conventional foods, followed by dietary supplements and fortified foods, are the key sources of vitamin D, vitamin B6, and selenium intake in Dutch participants of the NU-AGE study. Nutr Res 36, 1171–1181.
112.Fabian, E, Bogner, M, Kickinger, A et al. (2012) Vitamin status in elderly people in relation to the use of nutritional supplements. J Nutr Health Aging 16, 206–212.
113.Jääskeläinen, T, Itkonen, ST, Lundqvist, A et al. (2017) The positive impact of general vitamin D food fortification policy on vitamin D status in a representative adult Finnish population: evidence from an 11-y follow-up based on standardized 25-hydroxyvitamin D data. Am J Clin Nutr 105, 1512–1520.
114.Max Rubner-Institut (2008) Nationale Verzehrsstudie II. Ergebnisbericht, Teil 2. Bundesforschungsinstitut für Ernährung und Lebensmittel, Karlsruhe, Germany.
117.Samaniego-Vaesken, M, Partearroyo, T, Olza, J et al. (2017) Iron intake and dietary sources in the Spanish population: findings from the ANIBES study. Nutrients 9, 203.