Arnalich, F, Garcia-Palomero, E, Lopez, J, Jiminez, M, Madero, R, Renart, J, Vazquez, JJ & Montiel, C (2000) Predictive value of nuclear factor kappaB activity and plasma cytokine levels in patients with sepsis. Infection and Immunity 68, 1942–1945.
Asano, H, Kobayashi, T, Uchida, K, Hayashi, S, Yokoyama, I, Inoko, H & Takagi, H (1997) Significance of tumor necrosis factor microsatellite polymorphism in renal transplantation. Tissue Antigens 50, 484–488.
Beale, RJ, Bryg, DJ & Bihari, DJ (1999) Immunonutrition in the critically ill: A systematic review of clinical outcome. Critical Care Medicine 27, 2799–2805.
Boya, P, de la Pena, A, Beloqui, O, Larrea, E, Conchillo, M, Castelruiz, Y, Civeira, MP & Prieto, J (1999) Antioxidant status and glutathione metabolism in peripheral blood mononuclear cells from patients with chronic hepatitis C. Journal of Hepatology 31, 808–814.
Braga, M, Gionotti, L, Radaelli, G, Vignoli, A, Mori, G, Gentilini, O & di Carlo, V (1999) Perioperative immunonutrition in patients undergoing cancer surgery. Results of a randomized double-blind phase 3 trial. Archives of Surgery 134, 428–433.
Breitkreutz, R, Pittack, N, Nebe, CT, Schuster, D, Brust, J, Beichert, M, Hack, V, Daniel, V, Edler, L & Droge, W (2000) Improvement of immune functions in HIV infection by sulfur supplementation: Two randomized trials. Journal of Molecular Medicine 78, 55–62.
Calder, PC (1997) n-3 Polyunsaturated fatty acids and cytokine production in health and disease. Annals of Nutrition and Metabolism 41, 203–234.
Cao, Y, Feng, Z, Hoos, A & Klimberg, VS (1998) Glutamine enhances gut glutathione production. Journal of Parenteral and Enteral Nutrition 22, 224–227.
Choi, SS, Gatanaga, M, Granger, GA & Gatanaga, T (1996) Prostaglandin-E2 regulation of tumor necrosis factor receptor release in human monocytic THP-1 cells. Cellular Immunology 170, 178–184.
Cowley, HC, Bacon, PJ, Goode, HF, Webster, NR, Jones, JG & Menon, DK (1996) Plasma antioxidant potential in severe sepsis: A comparison of survivors and nonsurvivors. Critical Care Medicine 24, 1179–1183.
Denno, R, Rounds, JD, Faris, R, Halejko, LB & Wilmore, DW (1996) Glutamine enriched TPN enhances plasma glutathione in resting state. Journal of Surgical Research 61, 35–38.
Dröge, W, Schulze-Osthoff, K, Mihm, S, Galter, D, Schenk, H, Eck, HP, Roth, S & Gmünder, H (1994) Functions of glutathione and glutathione disulphide in immunology and immunopathology. FASEB Journal 8, 1131–1138.
Elia, M (1992) Glutamine in parenteral nutrition. International Journal of Food Science and Nutrition 43, 47–49.
Endres, S, Ghorbani, R, Kelley, VE, Georgilis, K, Lonnemann, G, van der Meer, JWM, Cannon, JG, Rogers, TS, Klempner, MS, Weber, PC, Schaefer, EJ, Wolff, SM & Dinarello, CA (1989) The effect of dietary supplementation with n-3 polyunsaturated fatty acids on the synthesis of interleukin-1 and tumor necrosis factor by mononuclear cells. New England Journal of Medicine 320, 265–271.
Gadek, JE, De Michele, SJ, Karlstad, MD, Pocht, ER, Donahoe, M, Albertson, TE, Van Hoozen, C, Wennberg, AK, Nelson, JL, Nourselehi, M and the Enteral Nutrition in ARDS Study Group (1999) Effect of enteral feeding with eicosapentaenoic acid, g-linolenic acid, and antioxidants in patients with acute respiratory distress syndrome. Critical Care Medicine 27, 1409–1420.
Gerster, H (1995) The use of n-3 PUFAs (fish oil) in enteral nutrition. International Journal of Vitamin and Nutrition Research 65, 3–20.
Gionotti, L, Braga, M, Fortis, C, Soldini, L, Vignoli, A, Colombo, S, Radaelli, G & di Carlo, V (1999) A prospective randomized clinical trial on perioperative feeding with arginine, omega 3 fatty acid, and RNA-enriched enteral diet. Effect on host response and nutrient status. Journal of Parenteral and Enteral Nutrition 23, 314–320.
Grimble, RF (1998a) Nutritional modulation of cytokine biology. Nutrition 14, 634–640.
Grimble, RF (1998b) Dietary lipids and the inflammatory response. Proceedings of the Nutrition Society 57, 535–542.
Grimble, RF, Calder, PC, Howell, WM, O'Reilly, GM, Turner, S, Markovic, O & East, JM (2001) The ability of fish oil to suppress TNF-α production by peripheral blood mononuclear cells in healthy men is associated with polymorphisms in genes which influence TNF-α production. American Journal of Clinical Nutrition (In the Press).
Hohler, T, Kruger, A, Gerken, G, Schneider, PM, Meyer zum Buschenefelde, KH & Rittner, C (1998) A tumor necrosis factor-alpha (TNF-alpha) promoter polymorphism is associated with chronic hepatitis C infection. Journal of Medical Virology 54, 173–177.
Houdijk, APJ, Rijnsburger, ER, Jansen, J, Wesdorp, RIC, Weiss, JK, McCamish, MA, Teerlink, T, Meuwissen, SGM, Haarman, HJThM, Thijs, LG & Van Leeuwen, PAM (1998) Randomised trial of glutamine-enriched enteral nutrition on infectious morbidity in patients with multiple trauma. Lancet 352, 772–776.
Hutchinson, IV, Pravica, V, Hajeer, A & Sinnott, PJ (1999) Identification of high and low responders to allographs. Review in Immunogenetics 1, 323–333.
Jackson, MJ, McArdle, A & McArdle, F (1998) Antioxidant micronutrients and gene expression. Proceedings of the Nutrition Society 57, 301–305.
Jacob, CO, Franek, Z, Lewis, GD, Koo, M, Hansen, JA & McDevitt, HO (1990) Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor-a: Relevance to genetic predisposition to systemic lupus erythematosus. Proceedings of the National Academy of Sciences USA 87, 1233–1237.
Kelley, DS, Taylor, PC, Nelson, GJ, Schmidt, PC, Ferretti, A, Erickson, KL, Yu, R, Chandra, RK & Mackay, BE (1999) Docosahexaenoic acid ingestion inhibits natural killer cell activity and production of inflammatory mediators in healthy men. Lipids 34, 317–324.
Loguercio, C, Blanco, FD, De Girolamo, V, Disalvo, D, Nardi, G, Parente, A & Blanco, CD (1999) Ethanol consumption, amino acid and glutathione blood levels in patients with and without chronic liver disease. Alcohol Clinical and Experimental Research 23, 1780–1784.
Luo, JL, Hammarqvist, F, Andersson, K & Wernerman, J (1996) Skeletal muscle glutathione after surgical trauma. Annals of Surgery 223, 420–427.
McGuire, W, Hill, AV, Allsopp, CE, Greenwood, BM & Kwaitkowski, D (1994) Variations in the TNF-α promoter region associated with susceptibility to cerebral malaria. Nature 371, 508–511.
McWhirter, JP & Pennington, CR (1994) Incidence and recognition of malnutrition in hospital. British Medical Journal 308, 945–948.
Majetschak, M, Flohe, S, Obertacke, V, Schroder, J, Staubach, K, Nast-Kolb, D, Schade, V & Stuber, F (1999) Relationships of a TNF gene polymorphism to severe sepsis in trauma patients. Annals of Surgery 230, 207–214.
Meydani, SN, Meydani, M, Blumberg, JB, Leka, LS, Silber, G, Loszewski, R, Thompson, C, Pedrosa, MC, Diamond, RD & Stoller, D (1997) Vitamin E supplementation and in vivo immune response in healthy subjects. A randomized controlled trial. Journal of the American Medical Association 277, 1370–1386.
Micke, P, Beeh, KM, Schlaak, JF & Buhl, R (2001) Oral supplementation with whey proteins increases plasma glutathione levels in HIV-infected patients. European Journal of Clinical Investigation 31, 171–178.
Mol, JTM, de Rijke, YB, Demacher, PNM & Stalenhoef, AFH (1997) Plasma levels of lipid and cholesterol oxidation products and cytokines in diabetes mellitus and smokers: effect of vitamin E treatment. Atherosclerosis 129, 169–176.
Morlion, BJ, Stehle, P, Wachtler, P, Siedhoff, H-P, Koller, M, Konig, W, Furst, P & Puchstein, C (1998) Total parenteral nutrition with glutamine dipeptide after major surgery. A double blind controlled study. Annals of Surgery 227, 302–308.
Newsholme, EA, Crabtree, B, Salleh, M & Ardawi, M (1985) Glutamine metabolism in lymphocytes. Its biochemistry, physiology and clinical importance. Quarterly Journal of Experimental Physiology 70, 473–489.
Nuttall, SL, Dunne, F, Kendall, MJ & Martin, U (1999) Age-dependent oxidative stress in elderly patients with non-insulin-dependent diabetes mellitus. Quarterly Journal of Medicine 92, 33–38.
O'Flaherty, L & Bouchier-Hayes, DJ (1999) Immunonutrition and surgical practice. Proceedings of the Nutrition Society 58, 831–837.
Pociot, F, Briant, L & Jongeneel, CV (1993) Association of tumor necrosis factor (TNF) and class II major histocompatibility complex alleles with the secretion of TNF-α and TNF-β by human mononuclear cells: a possible link to insulin-dependent diabetes mellitus. European Journal of Immunology 23, 224–231.
Reid, M, Badaloo, A, Forrester, T, Morlese, JF, Frazer, M, Heird, WC & Jahoor, F (2000) In vivo rates of erythrocyte glutathione synthesis in children with severe protein-energy malnutrition. American Journal of Physiology 278, E405–E412.
Ross, R (1993) The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 362, 801–809.
Spapen, H, Zhang, H, Demanet, C, Vleminckx, W, Vincent, JL & Huyghens, L (1998) Does N-acetyl cysteine influence cytokine response during early human septic shock? Chest 113, 1616–1624.
Stüber, F, Petersen, M & Bokelmann, FA (1996) Genomic polymorphisms within the tumor necrosis factor locus influences plasma TNF-α concentrations and outcome of patients with sepsis. Critical Care Medicine 24, 381–384.
Turner, D, Grant, SC, Yonan, N, Sheldon, S, Dyer, PA, Sinnott, PJ & Hutchinson, IV (1997) Cytokine gene polymorphism and heart transplant rejection. Transplantation 64, 776–779.
Wu, D, Meydani, SN, Sastre, J, Hayek, M & Meydani, M (1994) In vitro glutathione supplementation enhances interleukin-2 production and mitogenic responses in peripheral blood mononuclear cells from young and old subjects. Journal of Nutrition 124, 655–663.
Yaqoob, P, Pala, HS, Cortina-Borja, M, Newsholme, EA & Calder, PC (2000) Encapsulated fish oil enriched in alpha-tocopherol alters plasma phospholipid and mononuclear cell fatty acid compositions but not mononuclear cell functions. European Journal of Clinical Nutrition 30, 399–410.