Skip to main content
    • Aa
    • Aa
  • Access
  • Cited by 103
  • Cited by
    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.

    Sharma, Pradeep and Singh, Rajender 2011. RNAi Technology.

    Edwards, Christine Parrett, Alison and Khanna, Sheila 2006. Carbohydrates in Food, Second Edition.

    Illanes, A. and Guerrero, C. 2016. Lactose-Derived Prebiotics.

    Yu, Xurun Zhang, Jing Shao, Shanshan Yu, Heng Xiong, Fei and Wang, Zhong 2015. Morphological and physicochemical properties of bulb and bulbil starches fromLilium lancifolium. Starch - Stärke, Vol. 67, Issue. 5-6, p. 448.

    Raigond, Pinky Ezekiel, Rajarathnam and Raigond, Baswaraj 2015. Resistant starch in food: a review. Journal of the Science of Food and Agriculture, Vol. 95, Issue. 10, p. 1968.

    Tsatsaragkou, Kleopatra Paximada, Paraskevi Protonotariou, Stylliani and Mandala, Ioanna 2015. Handbook of Food Processing.

    Rose, Devin J. and Hamaker, Bruce R. 2011. Nondigestible Carbohydrates and Digestive Health.

    Lamsal, Buddhi P 2012. Production, health aspects and potential food uses of dairy prebiotic galactooligosaccharides. Journal of the Science of Food and Agriculture, Vol. 92, Issue. 10, p. 2020.

    Bird, A. Conlon, M. Christophersen, C. and Topping, D. 2010. Resistant starch, large bowel fermentation and a broader perspective of prebiotics and probiotics. Beneficial Microbes, Vol. 1, Issue. 4, p. 423.

    Thompson, Donald B. 2011. Modulations of Starch Structure with Potential to Influence Health. Australian Journal of Chemistry, Vol. 64, Issue. 11, p. 1485.

    Rastall, R.A. 2010. Functional Oligosaccharides: Application and Manufacture. Annual Review of Food Science and Technology, Vol. 1, Issue. 1, p. 305.

    Oomah, B. Dave Patras, Ankit Rawson, Ashish Singh, Narpinder and Compos-Vega, Rocio 2011. Pulse Foods.

    Nasrin, Taslima Ayesha Aktar and Anal, Anil Kumar 2014. Functional Foods and Dietary Supplements.

    Sommer, Felix and Bäckhed, Fredrik 2016. Know your neighbor: Microbiota and host epithelial cells interact locally to control intestinal function and physiology. BioEssays, Vol. 38, Issue. 5, p. 455.

    Lunn, J. and Buttriss, J. L. 2007. Carbohydrates and dietary fibre. Nutrition Bulletin, Vol. 32, Issue. 1, p. 21.

    Laurentin, A. and Edwards, C.A. 2005. Encyclopedia of Human Nutrition.

    Fardet, Anthony 2015. A shift toward a new holistic paradigm will help to preserve and better process grain products’ food structure for improving their health effects. Food Funct., Vol. 6, Issue. 2, p. 363.

    Tousen, Yuko Abe, Fumiko Ishida, Tatsuya Uehara, Mariko and Ishimi, Yoshiko 2011. Resistant starch promotes equol production and inhibits tibial bone loss in ovariectomized mice treated with daidzein. Metabolism, Vol. 60, Issue. 10, p. 1425.

    Cho, Susan and Finocchiaro, E 2009. Handbook of Prebiotics and Probiotics Ingredients.

    Laurentin, A. and Edwards, C.A. 2013. Encyclopedia of Human Nutrition.

  • Proceedings of the Nutrition Society, Volume 62, Issue 1
  • February 2003, pp. 171-176

Resistant starch as a prebiotic and synbiotic: state of the art

  • David L. Topping (a1), Michihiro Fukushima (a1) (a2) and Anthony R. Bird (a1)
  • DOI:
  • Published online: 05 March 2007

Non-infectious diseases such as CHD and certain cancers have become major causes of death and disability in affluent countries. Probiotics (principally lactic acid bacteria; LAB) may assist in lowering the risk of these diseases. Experimental studies with probiotics have given generally inconclusive outcomes for infectious disease and for biomarkers for non-infectious disease. In part this situation may reflect their inability to colonise the adult human gut effectively. Prebiotics can assist in promoting colonisation, and resistant starch (RS), as a high-amylose starch, is a prebiotic and synbiotic. This starch exerts its synbiotic action through adhesion of the bacteria to the granule surface. Consumption of RS assists in recovery from infectious diarrhoea in man and animals. A rice porridge, high in RS, appears to modify the autochthonous porcine large-bowel microflora favourably through lowering Escherichia coli and coliform numbers. Many of the beneficial effects of RS on large-bowel function appear to beexerted through short-chain fatty acids (SCFA) formed by bacterial fermentation. In man LAB are found in relatively highest numbers in milk-fed infants where theprofile of fermentation products differs quite markedly from that in adults. It appearsunlikely that ingestion of current probiotics will alter either total SCFA or the proportions of the major acids. More emphasis needs to be given to the investigation of the effects of complex carbohydrates, including RS, on the autochthonous microflora of the human large bowel.

    • Send article to Kindle

      To send this article to your Kindle, first ensure is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle.

      Note you can select to send to either the or variations. ‘’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      Resistant starch as a prebiotic and synbiotic: state of the art
      Available formats
      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your Dropbox account. Find out more about sending content to Dropbox.

      Resistant starch as a prebiotic and synbiotic: state of the art
      Available formats
      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your Google Drive account. Find out more about sending content to Google Drive.

      Resistant starch as a prebiotic and synbiotic: state of the art
      Available formats
Corresponding author
*Corresponding author: Dr David L. Topping, fax +618 8303 8899,
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

P Colonna & C Mercier (1985) Gelatinization and melting of maize starches with normal and high amylose phenotypes. Phytochemistry 24, 16671674.

JH Cummings & GT Macfarlane (1991) The control and consequences of bacterial fermentation in the human colon. Journal of Applied Bacteriology 70, 443459.

CA Edwards , AM Parrett , SE Balmer & BA Wharton (1994) Faecal short chain fatty acids in breast-fed and formula-fed infants. Acta Paediatrica 83, 459462.

MJ Govers , NJ Gannon , FR Dunshea , PR Gibson & JG Muir (1999) Wheat bran affects the site of fermentation of resistant starch and luminal indexes related to colon cancer risk: a study in pigs. Gut 45, 840847.

DJ Hampson , ID Robertson , T La , SL Oxberry & DW Pethick (2000) Influences of diet and vaccination on colonisation of pigs by the intestinal spirochaete. Brachyspira (Serpulina) pilosicoli. Veterinary Microbiology 73, 7584.

LT Hansen , PM Allan-Wojtas , YL Jin & AT Paulson (2002) Survival of Ca-alginate microencapsulated Bifidobacterium spp. in milk and simulated gastrointestinal conditions. Food Microbiology 19, 3545.

MI McBurney (1991) Starch malabsorption and stool excretion are influenced by the menstrual cycle in women consuming lowfibre Western diets. Scandinavian Journal of Gastroenterology 26, 880886.

AS Naidu , WR Bidlack & RA Clemens (1999) Probiotic spectra of lactic acid bacteria (LAB). Critical Reviews in Food Science 39, 13126.

L Nase , K Hatakka , E Savilahti , M Saxelin , A Ponka , T Poussa , R Korpela & JH Meurman (2001) Effect of long-term consumption of a probiotic bacterium, Lactobacillus rhamnosus GG, in milk on dental caries and caries risk in children. Caries Research 35, 412420.

GH Rabbani , T Teka , B Zaman , N Majid , M Khatun & GJ Fuchs (2001) Clinical studies in persistent diarrhea: dietary management with green banana or pectin in Bangladeshi children. Gastroenterology 121, 554560.

BS Ramakrishna , S Venkataraman , P Srinivasan , P Dash , GP Young & HJ Binder (2000) Amylase-resistant starch plus oral rehydration solution for cholera. New England Journal of Medicine 342, 308313.

CW van Niel , C Feudtner , MM Garrison & DA Christakis (2002) Lactobacillus therapy for acute infectious diarrhea in children: a meta-analysis. Pediatrics 109, 678684.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Proceedings of the Nutrition Society
  • ISSN: 0029-6651
  • EISSN: 1475-2719
  • URL: /core/journals/proceedings-of-the-nutrition-society
Please enter your name
Please enter a valid email address
Who would you like to send this to? *